Macrophages homing to metastatic lymph nodes can be monitored with ultrasensitive ferromagnetic iron-oxide nanocubes and a 1.5T clinical 0 scanner

PLoS ONE

Volumn 7, Issue 1, 2012, Pages

  Cho, Hye Rim ^a   Choi, Seung Hong ^a   Lee, Nohyun ^b   Hyeon, Taeghwan ^b   Kim, Hyeonjin ^a   Moon, Woo Kyung ^a  

^a Seoul National University College of Medicine   (South Korea)

^b Seoul National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

CONTRAST MEDIUM; FERROMAGNETIC MATERIAL; IRON OXIDE; DIAGNOSTIC AGENT; FERRIC ION; FERRIC OXIDE; MAGNETITE NANOPARTICLE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; AXILLARY LYMPH NODE; CELL HOMING; CELL ISOLATION; CELL LABELING; CELL MIGRATION; CELL VIABILITY; CONTROLLED STUDY; FLUORESCENCE ACTIVATED CELL SORTING; IN VIVO STUDY; INGUINAL LYMPH NODE; INTERMETHOD COMPARISON; LYMPH NODE METASTASIS; MACROPHAGE; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEAR MAGNETIC RESONANCE SCANNER; PERITONEUM MACROPHAGE; PHAGOCYTOSIS; PRIMARY TUMOR; ANIMAL; BAGG ALBINO MOUSE; CELL MOTION; CELL SURVIVAL; DISEASE MODEL; FLOW CYTOMETRY; HUMAN; INSTRUMENTATION; INTRACELLULAR SPACE; MALE; MELANOMA; METABOLISM; METHODOLOGY; PATHOLOGY; ULTRASTRUCTURE;

MUS; MUS MUSCULUS;

ANIMALS; CELL MOVEMENT; CELL SURVIVAL; DISEASE MODELS, ANIMAL; FERRIC COMPOUNDS; FLOW CYTOMETRY; HUMANS; INTRACELLULAR SPACE; LYMPHATIC METASTASIS; MACROPHAGES, PERITONEAL; MAGNETIC RESONANCE IMAGING; MAGNETITE NANOPARTICLES; MALE; MELANOMA; MICE; MICE, INBRED BALB C; PHAGOCYTOSIS;

EID: 84855566974     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0029575     Document Type: Article

References (38)

1. Mumprecht V, Detmar M, (2009) Lymphangiogenesis and cancer metastasis. J Cell Mol Med 13: 1405-1416.
2. Sleeman JP, Thiele W, (2009) Tumor metastasis and the lymphatic vasculature. Int J Cancer 125: 2747-2756.
3. Foster PJ, Dunn EA, Karl KE, Snir JA, Nycz CM, et al. (2008) Cellular magnetic resonance imaging: in vivo imaging of melanoma cells in lymph nodes of mice. Neoplasia 10: 207-216.
4. Weissleder R, (2002) Scaling down imaging: molecular mapping of cancer in mice. Nat Rev Cancer 2: 11-18.
5. Hill JM, Dick AJ, Raman VK, Thompson RB, Yu ZX, et al. (2003) Serial cardiac magnetic resonance imaging of injected mesenchymal stem cells. Circulation 108: 1009-1014.
6. Modo M, Hoehn M, Bulte JW, (2005) Cellular MR imaging. Mol Imaging 4: 143-164.
7. Heyn C, Ronald JA, Mackenzie LT, MacDonald IC, Chambers AF, et al. (2006) In vivo magnetic resonance imaging of single cells in mouse brain with optical validation. Magn Reson Med 55: 23-29.
8. Shapiro EM, Sharer K, Skrtic S, Koretsky AP, (2006) In vivo detection of single cells by MRI. Magn Reson Med 55: 242-249.
9. Virchow R, (1863) Aetologie der neoplastichen Geschwulste/Pathogenie der neoplastischen Geschwulste. Die Krankhaften Geschwulste Berlin Verlag von August Hirschwald pp. 57-101.
10. van Ravenswaay Claasen HH, Kluin PM, Fleuren GJ, (1992) Tumor infiltrating cells in human cancer. On the possible role of CD16+ macrophages in antitumor cytotoxicity. Lab Invest 67: 166-174.
11. Stephens TC, Currie GA, Peacock JH, (1978) Repopulation of gamma-irradiated Lewis lung carcinoma by malignant cells and host macrophage progenitors. Br J Cancer 38: 573-582.
12. Zhang J, Patel L, Pienta KJ, (2010) CC chemokine ligand 2 (CCL2) promotes prostate cancer tumorigenesis and metastasis. Cytokine Growth Factor Rev 21: 41-48.
13. McBride WH, (1986) Phenotype and functions of intratumoral macrophages. Biochim Biophys Acta 865: 27-41.
14. Deepak P, Acharya A, (2010) Anti-tumor immunity and mechanism of immunosuppression mediated by tumor cells: role of tumor-derived soluble factors and cytokines. Int Rev Immunol 29: 421-458.
15. Valable S, Barbier EL, Bernaudin M, Roussel S, Segebarth C, et al. (2007) In vivo MRI tracking of exogenous monocytes/macrophages targeting brain tumors in a rat model of glioma. Neuroimage 37 (Suppl 1): S47-S58.
16. Choi MR, Stanton-Maxey KJ, Stanley JK, Levin CS, Bardhan R, et al. (2007) A cellular Trojan Horse for delivery of therapeutic nanoparticles into tumors. Nano Lett 7: 3759-3765. 17.
17. Loebinger MR, Kyrtatos PG, Turmaine M, Price AN, Pankhurst Q, et al. (2009) Magnetic resonance imaging of mesenchymal stem cells homing to pulmonary metastases using biocompatible magnetic nanoparticles. Cancer Res 69: 8862-8867.
18. Bingle L, Brown NJ, Lewis CE, (2002) The role of tumour-associated macrophages in tumour progression: implications for new anticancer therapies. J Pathol 196: 254-265.
19. Serganova I, Doubrovin M, Vider J, Ponomarev V, Soghomonyan S, et al. (2004) Molecular imaging of temporal dynamics and spatial heterogeneity of hypoxia-inducible factor-1 signal transduction activity in tumors in living mice. Cancer Res 64: 6101-6108.
20. Lee JS, Sohn JY, Jung HD, Kim ST, Lee KG, et al. (2008) Pace of macrophage recruitment during different stages of soft tissue infection: semi-quantitative evaluation by in vivo magnetic resonance imaging. Eur Radiol 18: 2033-2039.
21. Lee JS, Kang HJ, Gong G, Jung HD, Lim KH, et al. (2006) MR imaging of in vivo recruitment of iron oxide-labeled macrophages in experimentally induced soft-tissue infection in mice. Radiology 241: 142-148.
22. Chae EY, Song EJ, Sohn JY, Kim ST, Woo CW, et al. (2010) Allogeneic renal graft rejection in a rat model: in vivo MR imaging of the homing trait of macrophages. Radiology 256: 847-854.
23. Kim D, Lee N, Park M, Kim BH, An K, et al. (2009) Synthesis of uniform ferrimagnetic magnetite nanocubes. J Am Chem Soc 131: 454-455.
24. Lee N, Kim H, Choi SH, Park M, Kim D, et al. (2011) Magnetosome-like ferrimagnetic iron oxide nanocubes for highly sensitive MRI of single cells and transplanted pancreatic islets. Proc Natl Acad Sci U S A 108: 2662-2667.
25. Minchinton AI, Tannock IF, (2006) Drug penetration in solid tumours. Nat Rev Cancer 6: 583-592.
26. Ohlfest JR, Demorest ZL, Motooka Y, Vengco I, Oh S, et al. (2005) Combinatorial antiangiogenic gene therapy by nonviral gene transfer using the sleeping beauty transposon causes tumor regression and improves survival in mice bearing intracranial human glioblastoma. Mol Ther 12: 778-788.
27. Nakamura K, Ito Y, Kawano Y, Kurozumi K, Kobune M, et al. (2004) Antitumor effect of genetically engineered mesenchymal stem cells in a rat glioma model. Gene Ther 11: 1155-1164.
28. Ehtesham M, Kabos P, Kabosova A, Neuman T, Black KL, et al. (2002) The use of interleukin 12-secreting neural stem cells for the treatment of intracranial glioma. Cancer Res 62: 5657-5663.
29. Brigati C, Noonan DM, Albini A, Benelli R, (2002) Tumors and inflammatory infiltrates: friends or foes? Clin Exp Metastasis 19: 247-258.
30. Coussens LM, Werb Z, (2002) Inflammation and cancer. Nature 420: 860-867.
31. Amsalem Y, Mardor Y, Feinberg MS, Landa N, Miller L, et al. (2007) Iron-oxide labeling and outcome of transplanted mesenchymal stem cells in the infarcted myocardium. Circulation 116: I38-45.
32. Terrovitis J, Stuber M, Youssef A, Preece S, Leppo M, et al. (2008) Magnetic resonance imaging overestimates ferumoxide-labeled stem cell survival after transplantation in the heart. Circulation 117: 1555-1562.
33. Fidler IJ, (1973) Selection of successive tumour lines for metastasis. Nat New Biol 242: 148-149.
34. Nguyen DX, (2011) Tracing the origins of metastasis. J Pathol 223: 195-204.
35. Turchyn LR, Baqinski TJ, Renkiewicz RR, Lesch CA, Mobley JL, (2007) Phenotypic and functional analysis of murine resident and induced peritoneal macrophages. Comp Med 57: 574-580.
36. Fortier AH, Falk LA, (2005) Isolation of Murine Macropahges. In: Coligan JE, Bierer B, Kruisbeek AM, Margulies DH, Shevach EM, Strober W, editors. Current protocols in immunology New York John Wiley and Sons pp. 14.11.11-14.11.19.
37. Hauger O, Delalande C, Deminiere C, Fouqueray B, Ohayon C, et al. (2000) Nephrotoxic nephritis and obstructive nephropathy: evaluation with MR imaging enhanced with ultrasmall superparamagnetic iron oxide-preliminary findings in a rat model. Radiology 217: 819-826.
38. Weissleder R, Stark DD, Engelstad BL, Bacon BR, Compton CC, et al. (1989) Superparamagnetic iron oxide: pharmacokinetics and toxicity. AJR Am J Roentgenol 152: 167-173.