STIM1/Orai1 contributes to sex differences in vascular responses to calcium in spontaneously hypertensive rats

Clinical Science

Volumn 122, Issue 5, 2012, Pages 215-226

  Giachini, Fernanda R C ^a,b   Lima, Victor V ^a,c   Filgueira, Fernando P ^c   Dorrance, Anne M ^d   Carvalho, Maria Helena C ^c   Fortes, Zuleica B ^c   Webb, R Clinton ^a   Tostes, Rita C ^a,c  

^a MEDICAL COLLEGE OF GEORGIA   (United States)

^b University of Mato Grosso   (Brazil)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

^d MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

Aorta; Calcium; Hypertension; Orai1; Sex difference; Stromal interaction molecule 1 (STIM1); Vascular protection

Indexed keywords

CALCIUM ION; CALCIUM RELEASE ACTIVATED CALCIUM CHANNEL 1; ESTRADIOL; NEUTRALIZING ANTIBODY; PROGESTERONE; STROMAL INTERACTION MOLECULE 1; TESTOSTERONE; THAPSIGARGIN; CALCIUM; CALCIUM CHANNEL; MEMBRANE PROTEIN; ORAI1 PROTEIN, RAT; SEX HORMONE; STIM1 PROTEIN, RAT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AORTA; ARTERY CONSTRICTION; ARTERY ENDOTHELIUM; ARTICLE; BLOOD VESSEL REACTIVITY; BODY WEIGHT; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CONTROLLED STUDY; FEMALE; MALE; NONHUMAN; OVARIECTOMY; PRIORITY JOURNAL; RAT; SARCOPLASMIC RETICULUM; SEX DIFFERENCE; STROKE PRONE SPONTANEOUSLY HYPERTENSIVE RAT; SYSTOLIC BLOOD PRESSURE; WISTAR KYOTO RAT; ANIMAL; CALCIUM SIGNALING; DRUG EFFECT; HOMEOSTASIS; HYPERTENSION; IN VITRO STUDY; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; SEXUAL DEVELOPMENT; SIGNAL TRANSDUCTION; SPONTANEOUSLY HYPERTENSIVE RAT;

ANIMALS; AORTA; BODY WEIGHT; CALCIUM; CALCIUM CHANNELS; CALCIUM SIGNALING; FEMALE; GONADAL STEROID HORMONES; HOMEOSTASIS; HYPERTENSION; MALE; MEMBRANE GLYCOPROTEINS; OVARIECTOMY; RATS; RATS, INBRED SHR; RATS, INBRED WKY; SEX CHARACTERISTICS; SIGNAL TRANSDUCTION;

EID: 84855517540     PISSN: 01435221     EISSN: None     Source Type: Journal    
DOI: 10.1042/CS20110312     Document Type: Article

References (41)

1. 2+ channel function. J. Cell Biol. 169, 435-445
2. 2+ influx. Curr. Biol. 15, 1235-1241
3. 2+ channels. Proc. Natl. Acad. Sci. U.S.A. 103, 4040-4045
4. 2+ entry. Science 312, 1220-1223
5. Xu, P., Lu, J., Li, Z., Yu, X., Chen, L. and Xu, T. (2006) Aggregation of STIM1 underneath the plasma membrane induces clustering of Orai1. Biochem. Biophys. Res. Commun. 350, 969-976
6. 2+ entry. Cell Calcium 42, 163-172
7. Feske, S., Gwack, Y., Prakriya, M., Srikanth, S., Puppel, S. H., Tanasa, B., Hogan, P. G., Lewis, R. S., Daly, M. and Rao, A. (2006) A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function. Nature 441, 179-185
8. Noon, J. P., Rice, P. J. and Baldessarini, R. J. (1978) Calcium leakage as a cause of the high resting tension in vascular smooth muscle from the spontaneously hypertensive rat. Proc. Natl. Acad. Sci. U.S.A. 75, 1605-1607
9. Orlov, S., Resink, T. J., Bernhardt, J., Ferracin, F. and Buhler, F. R. (1993) Vascular smooth muscle cell calcium fluxes. Regulation by angiotensin II and lipoproteins. Hypertension 21, 195-203
10. Bendhack, L. M., Sharma, R. V. and Bhalla, R. C. (1992) Altered signal transduction in vascular smooth muscle cells of spontaneously hypertensive rats. Hypertension 19, II142-II148
11. Cortes, S. F., Lemos, V. S. and Stoclet, J. C. (1997) Alterations in calcium stores in aortic myocytes from spontaneously hypertensive rats. Hypertension 29, 1322-1328
12. Giachini, F. R., Chiao, C. W., Carneiro, F. S., Lima, V. V., Carneiro, Z. N., Dorrance, A. M., Tostes, R. C. and Webb, R. C. (2008) Increased activation of stromal interaction molecule-1/Orai-1 in aorta from hypertensive rats: a novel insight into vascular dysfunction. Hypertension 53, 409-416
13. 2+ handling? J. Hypertens. 20, 2139-2140
14. Loukotova, J., Kunes, J. and Zicha, J. (2002) Gender-dependent difference in cell calcium handling in VSMC isolated from SHR: the effect of angiotensin II. J. Hypertens. 20, 2213-2219
15. Karaki, H., Kubota, H. and Urakawa, N. (1979) Mobilization of stored calcium for phasic contraction induced by norepinephrine in rabbit aorta. Eur. J. Pharmacol. 56, 237-245
16. Perry, P. A. and Webb, R. C. (1991) Agonist-sensitive calcium stores in arteries from steroid hypertensive rats. Hypertension 17, 603-611
17. Morris, M. C., Depollier, J., Mery, J., Heitz, F. and Divita, G. (2001) A peptide carrier for the delivery of biologically active proteins into mammalian cells. Nat. Biotechnol. 19, 1173-1176
18. Keller, M., Lidington, D., Vogel, L., Peter, B. F., Sohn, H. Y., Pagano, P. J., Pitson, S., Spiegel, S., Pohl, U. and Bolz, S. S. (2006) Sphingosine kinase functionally links elevated transmural pressure and increased reactive oxygen species formation in resistance arteries. FASEB J. 20, 702-704
19. Clarke, C. J., Forman, S., Pritchett, J., Ohanian, V. and Ohanian, J. (2008) Phospholipase C-δ1 modulates sustained contraction of rat mesenteric small arteries in response to noradrenaline, but not endothelin-1. Am. J. Physiol. Heart Circ. Physiol. 295, H826-H834
20. Cambotti, L. J., Cole, F. E., Gerall, A. A., Frohlich, E. D. and Macphee, A. A. (1984) Neonatal gonadal hormones and blood pressure in the spontaneously hypertensive rat. Am. J. Physiol. 247, E258-E264
21. Crofton, J. T. and Share, L. (1997) Gonadal hormones modulate deoxycorticosterone-salt hypertension in male and female rats. Hypertension 29, 494-499
22. Bohr, D. F. and Webb, R. C. (1988) Vascular smooth muscle membrane in hypertension. Annu. Rev. Pharmacol. Toxicol. 28, 389-409
23. Tostes, R. C., Fortes, Z. B., Callera, G. E., Montezano, A. C., Touyz, R. M., Webb, R. C. and Carvalho, M. H. (2008) Endothelin, sex and hypertension. Clin. Sci. 114, 85-97
24. Tostes, R. C., Nigro, D., Fortes, Z. B. and Carvalho, M. H. (2003) Effects of estrogen on the vascular system. Braz. J. Med. Biol. Res. 36, 1143-1158
25. 2+ entry mechanisms of vasoconstriction in Wistar-Kyoto and spontaneously hypertensive rats. Hypertension 34, 931-936
26. 2+ ]i in vascular smooth muscle cells of female rat. Am. J. Physiol. Cell Physiol. 278, C834-C844
27. 2+ entry mechanisms of arterial vasoconstriction by sex hormones. Clin. Exp. Pharmacol. Physiol. 26, 707-715
28. Loukotova, J., Kunes, J. and Zicha, J. (1998) Cytosolic free calcium response to angiotensin II in aortic VSMC isolated from male and female SHR. Physiol. Res. 47, 507-510
29. Peel, S. E., Liu, B. and Hall, I. P. (2008) ORAI and store-operated calcium influx in human airway smooth muscle cells. Am. J. Respir. Cell Mol. Biol. 38, 744-749
30. Dietrich, A., Kalwa, H., Storch, U.,Mederos, Y., Schnitzler, M., Salanova, B., Pinkenburg, O., Dubrovska, G., Essin, K., Gollasch, M., Birnbaumer, L. and Gudermann, T. (2007) Pressure-induced and store-operated cation influx in vascular smooth muscle cells is independent of TRPC1. Pflugers Arch. 455, 465-477
31. Peel, S. E., Liu, B. and Hall, I. P. (2006) A key role for STIM1 in store operated calcium channel activation in airway smooth muscle. Respir. Res. 7, 119
32. Takahashi, Y., Watanabe, H., Murakami, M., Ono, K., Munehisa, Y., Koyama, T., Nobori, K., Iijima, T. and Ito, H. (2007) Functional role of stromal interaction molecule 1 (STIM1) in vascular smooth muscle cells. Biochem. Biophys. Res. Commun. 361, 934-940
33. Hawkins, B. J., Irrinki, K. M., Mallilankaraman, K., Lien, Y. C., Wang, Y., Bhanumathy, C. D., Subbiah, R., Ritchie, M. F., Soboloff, J., Baba, Y. et al. (2010) S-glutathionylation activates STIM1 and alters mitochondrial homeostasis. J. Cell Biol. 190, 391-405
34. Chatham, J. C. and Marchase, R. B. (2010) The role of protein O-linked β-N-acetylglucosamine in mediating cardiac stress responses. Biochim. Biophys. Acta 1800, 57-66
35. Pozo-Guisado, E., Campbell, D. G., Deak, M., Alvarez-Barrientos, A., Morrice, N. A., Alvarez, I. S., Alessi, D. R. and Martin-Romero, F. J. (2010) Phosphorylation of STIM1 at ERK1/2 target sites modulates store-operated calcium entry. J. Cell Sci. 123, 3084-3093
36. Smyth, J. T., Petranka, J. G., Boyles, R. R., Dehaven, W. I., Fukushima, M., Johnson, K. L.,Williams, J. G. and Putney, Jr, J.W. (2009) Phosphorylation of STIM1 underlies suppression of store-operated calcium entry during mitosis. Nat. Cell Biol. 11, 1465-1472
37. 2+ entry. Biochim. Biophys. Acta 1803, 1083-1093
38. Watts, S. W., Traub, O. and Webb, R. C. (1994) Effects of ramipril on contractile oscillations in arteries from genetically hypertensive rats. Clin. Exp. Hypertens. 16, 881-898
39. Silva-Antonialli, M. M., Tostes, R. C., Fernandes, L., Fior-Chadi, D. R., Akamine, E. H., Carvalho, M. H., Fortes, Z. B. and Nigro, D. (2004) A lower ratio of AT1/AT2 receptors of angiotensin II is found in female than in male spontaneously hypertensive rats. Cardiovasc. Res. 62, 587-593
40. Gimenez, J., Garcia, P. M., Bonacasa, B., Carbonell, L. F., Quesada, T. and Hernandez, I. (2006) Effects of oestrogen treatment and angiotensin-converting enzyme inhibition on the microvasculature of ovariectomized spontaneously hypertensive rats. Exp. Physiol. 91, 261-268
41. Giachini, F. R., Webb, R. C. and Tostes, R. C. (2010) STIM and Orai proteins: players in sexual differences in hypertension-associated vascular dysfunction? Clin. Sci. 118, 391-396