Structural analysis of the core COMPASS family of histone H3K4 methylases from yeast to human

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 51, 2011, Pages 20526-20531

  Takahashi, Yoh Hei ^a   Westfield, Gerwin H ^b,c   Oleskie, Austin N ^b   Trievel, Raymond C ^c   Shilatifard, Ali ^a   Skiniotis, Georgios ^b,c  

^a STOWERS INSTITUTE FOR MEDICAL RESEARCH   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CORE COMPLEX OF PROTEINS ASSOCIATED WITH SET1; HISTONE H3 LYSINE 4 METHYLASE; METHYLTRANSFERASE; MULTIPROTEIN COMPLEX; UNCLASSIFIED DRUG;

ANTIBODY LABELING; ARTICLE; CRYOELECTRON MICROSCOPY; ENZYME ACTIVITY; ENZYME RECONSTITUTION; HISTONE METHYLATION; HUMAN; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN LOCALIZATION; YEAST;

ANIMALS; CONSERVED SEQUENCE; CRYOELECTRON MICROSCOPY; DNA METHYLATION; HISTONE-LYSINE N-METHYLTRANSFERASE; HISTONES; HUMANS; IMAGING, THREE-DIMENSIONAL; INSECTS; METHYLATION; MICROSCOPY, ELECTRON; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MYELOID-LYMPHOID LEUKEMIA PROTEIN; RECOMBINANT PROTEINS; SACCHAROMYCES CEREVISIAE;

EID: 84855488676     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1109360108     Document Type: Article

References (34)

1. Bhaumik SR, Smith E, Shilatifard A (2007) Covalent modifications of histones during development and disease pathogenesis. Nat Struct Mol Biol 14:1008-1016. (Pubitemid 350060343)
2. Shilatifard A (2006) Chromatin modifications by methylation and ubiquitination: implications in the regulation of gene expression. Annu Rev Biochem 75:243-269.
3. Zhang Y, Reinberg D (2001) Transcription regulation by histone methylation: interplay between different covalent modifications of the core histone tails. Genes Dev 15:2343-2360. (Pubitemid 32899739)
4. Miller T, et al. (2001) COMPASS: a complex of proteins associated with a trithoraxrelated SET domain protein. Proc Natl Acad Sci USA 98:12902-12907. (Pubitemid 33051292)
5. Krogan NJ, et al. (2002) COMPASS, a histone H3 (Lysine 4) methyltransferase required for telomeric silencing of gene expression. J Biol Chem 277:10753-10755. (Pubitemid 34952826)
6. Roguev A, et al. (2001) The Saccharomyces cerevisiae Set1 complex includes an Ash2 homologue and methylates histone 3 lysine 4. EMBO J 20:7137-7148. (Pubitemid 34062305)
7. Schlichter A, Cairns BR (2005) Histone trimethylation by Set1 is coordinated by the RRM, autoinhibitory, and catalytic domains. EMBO J 24:1222-1231. (Pubitemid 40516605)
8. Schneider J, et al. (2005) Molecular regulation of histone H3 trimethylation by COMPASS and the regulation of gene expression. Mol Cell 19:849-856. (Pubitemid 41316678)
9. Shilatifard A (2008) Molecular implementation and physiological roles for histone H3 lysine 4 (H3K4) methylation. Curr Opin Cell Biol 20:341-348.
10. Eissenberg JC, Shilatifard A (2010) Histone H3 lysine 4 (H3K4) methylation in development and differentiation. Dev Biol 339:240-249.
11. Southall SM, Wong PS, Odho Z, Roe SM, Wilson JR (2009) Structural basis for the requirement of additional factors for MLL1 SET domain activity and recognition of epigenetic marks. Mol Cell 33:181-191.
12. Dehe PM, et al. (2006) Protein interactions within the Set1 complex and their roles in the regulation of histone 3 lysine 4 methylation. J Biol Chem 281:35404-35412.
13. Lee JS, et al. (2007) Histone crosstalk between H2B monoubiquitination and H3 methylation mediated by COMPASS. Cell 131:1084-1096.
14. Nedea E, et al. (2008) The Glc7 phosphatase subunit of the cleavage and polyadenylation factor is essential for transcription termination on snoRNA genes. Mol Cell 29:577-587. (Pubitemid 351374686)
15. Cao F, et al. (2010) An Ash2L/RbBP5 heterodimer stimulates the MLL1 methyltransferase activity through coordinated substrate interactions with the MLL1 SET domain. PLoS One 5:e14102.
16. Patel A, Dharmarajan V, Vought VE, Cosgrove MS (2009) On the mechanism of multiple lysine methylation by the human mixed lineage leukemia protein-1 (MLL1) core complex. J Biol Chem 284:24242-24256.
17. Patel A, Vought VE, Dharmarajan V, Cosgrove MS (2011) A novel non-SET Domain multi-subunit methyltransferase required for sequential nucleosomal histone H3 methylation by the mixed lineage leukemia protein-1 (MLL1) core complex. J Biol Chem 286:3359-3369.
18. Brink J, et al. (2004) Experimental verification of conformational variation of human fatty acid synthase as predicted by normal mode analysis. Structure 12:185-191. (Pubitemid 38224542)
19. Menetret JF, et al. (2005) Architecture of the ribosome-channel complex derived from native membranes. J Mol Biol 348:445-457.
20. Odho Z, Southall SM, Wilson JR (2010) Characterization of a novel WDR5-binding site that recruits RbBP5 through a conserved motif to enhance methylation of histone H3 lysine 4 by mixed lineage leukemia protein-1. J Biol Chem 285:32967-32976.
21. Avdic V, et al. (2011) Structural and biochemical insights into MLL1 core complex assembly. Structure 19:101-108.
22. Takahashi YH, et al. (2009) Regulation of H3K4 trimethylation via Cps40 (Spp1) of COMPASS is monoubiquitination independent: implication for a Phe/Tyr switch by the catalytic domain of Set1. Mol Cell Biol 29:3478-3486.
23. Dou Y, et al. (2006) Regulation of MLL1 H3K4 methyltransferase activity by its core components. Nat Struct Mol Biol 13:713-719. (Pubitemid 44175164)
24. South PF, Fingerman IM, Mersman DP, Du HN, Briggs SD (2010) A conserved interaction between the SDI domain of Bre2 and the Dpy-30 domain of Sdc1 is required for histone methylation and gene expression. J Biol Chem 285:595-607.
25. Wysocka J, et al. (2005) WDR5 associates with histone H3 methylated at K4 and is essential for H3 K4 methylation and vertebrate development. Cell 121:859-872. (Pubitemid 40806418)
26. Cao R, et al. (2002) Role of histone H3 lysine 27 methylation in Polycomb-group silencing. Science 298:1039-1043. (Pubitemid 35247314)
27. Kuzmichev A, Nishioka K, Erdjument-Bromage H, Tempst P, Reinberg D (2002) Histone methyltransferase activity associated with a human multiprotein complex containing the Enhancer of Zeste protein. Genes Dev 16:2893-2905. (Pubitemid 35334738)
28. Nekrasov M, Wild B, Muller J (2005) Nucleosome binding and histone methyltransferase activity of Drosophila PRC2. EMBO Rep 6:348-353. (Pubitemid 40561627)
29. Kuzmichev A, Jenuwein T, Tempst P, Reinberg D (2004) Different EZH2-containing complexes target methylation of histone H1 or nucleosomal histone H3. Mol Cell 14:183-193. (Pubitemid 38515646)
30. Ohi M, Li Y, Cheng Y, Walz T (2004) Negative staining and image classification - powerful tools in modern electron microscopy. Biol Proced Online 6:23-34. (Pubitemid 38597695)
31. Frank J, et al. (1996) SPIDER and WEB: processing and visualization of images in 3D electron microscopy and related fields. J Struct Biol 116:190-199. (Pubitemid 26093143)
32. Radermacher M, Wagenknecht T, Verschoor A, Frank J (1987) Three-dimensional reconstruction from a single-exposure, random conical tilt series applied to the 50S ribosomal subunit of Escherichia coli. J Microsc 146:113-136.
33. Grigorieff N (2007) FREALIGN: high-resolution refinement of single particle structures. J Struct Biol 157:117-125.
34. Ludtke SJ, Baldwin PR, Chiu W (1999) EMAN: semiautomated software for high-resolution single-particle reconstructions. J Struct Biol 128:82-97. (Pubitemid 30013436)