Inhibition of dendritic cell migration by transforming growth factor-1 increases tumor-draining lymph node metastasis

Journal of Experimental and Clinical Cancer Research

Volumn 31, Issue 1, 2012, Pages

  Imai, Kazuhiro ^a   Minamiya, Yoshihiro ^a   Koyota, Souichi ^a   Ito, Manabu ^a   Saito, Hajime ^a   Sato, Yusuke ^a   Motoyama, Satoru ^a   Sugiyama, Toshihiro ^a   Ogawa, Jun Ichi ^a  

^a AKITA UNIVERSITY   (Japan)

Author keywords

dendritic cell; lymph node metastasis; migration; transforming growth factor 1; tumor draining lymph node

Indexed keywords

FLUORESCENT DYE; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BONE MARROW CELL; CANCER CELL CULTURE; CELL ACTIVATION; CELL MATURATION; CELL MIGRATION; CONTROLLED STUDY; DENDRITIC CELL; EAR; IMMUNE RESPONSE; INOCULATION; LYMPH NODE METASTASIS; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SQUAMOUS CELL CARCINOMA; ANIMAL; BIOSYNTHESIS; BONE MARROW; CELL MOTION; EXPERIMENTAL NEOPLASM; GENE VECTOR; IMMUNOLOGY; LYMPH NODE; METABOLISM; PATHOLOGY;

ANIMALS; BONE MARROW; CELL MOVEMENT; DENDRITIC CELLS; GENETIC VECTORS; LYMPH NODES; LYMPHATIC METASTASIS; MALE; MICE; NEOPLASMS, EXPERIMENTAL; NEOPLASMS, SQUAMOUS CELL; TRANSFORMING GROWTH FACTOR BETA;

EID: 84855476775     PISSN: None     EISSN: 17569966     Source Type: Journal    
DOI: 10.1186/1756-9966-31-3     Document Type: Article

References (24)

1. Intravital imaging illuminates transforming growth factor beta signaling switches during metastasis. Giampieri S, Pinner S, Sahai E, Cancer Res 2010 70 3435 3439 10.1158/0008-5472.CAN-10-0466 20424121
2. Targeting the transforming growth factor-beta signaling pathway in metastatic cancer. Korpal M, Kang Y, Eur J Cancer 2010 46 1232 1240 10.1016/j.ejca.2010.02.040 20307969
3. Transforming growth factor-beta and the immune response to malignant disease. Teicher BA, Clin Cancer Res 2007 13 6247 6251 10.1158/1078-0432.CCR-07- 1654 17975134 (Pubitemid 350075011)
4. Transforming growth factor-beta signaling in cancer invasion and metastasis. Leivonen SK, Kähäri VM, Int J Cancer 2007 121 2119 2124 10.1002/ijc.23113 17849476 (Pubitemid 47585589)
5. Distinct mechanisms of TGF-beta1-mediated epithelial-to-mesenchymal transition and metastasis during skin carcinogenesis. Han G, Lu SL, Li AG, He W, Corless CL, Kulesz-Martin M, Wang XJ, J Clin Invest 2005 115 1714 1723 10.1172/JCI24399 15937546 (Pubitemid 40979710)
6. Transforming growth factor beta-1 in rectal tumour, mucosa and plasma in relation to radiotherapy and clinical outcome in rectal cancer patients. Angenete E, Langenskiöld M, Palmgren I, Falk P, Oresland T, Ivarsson ML, Int J Colorectal Dis 2007 22 1331 1338 10.1007/s00384-007-0342-7 17657504 (Pubitemid 47456718)
7. Transforming growth factor beta1 is associated with angiogenesis, metastasis, and poor clinical outcome in prostate cancer. Wikström P, Stattin P, Franck-Lissbrant I, Damber JE, Bergh A, Prostate 1998 37 19 29 10.1002/(SICI)1097-0045(19980915)37:1<19::AID-PROS4>3.0.CO;2-3 9721065 (Pubitemid 28385181)
8. Transforming growth factor-beta1 level correlates with angiogenesis, tumor progression, and prognosis in patients with nonsmall cell lung carcinoma. Hasegawa Y, Takanashi S, Kanehira Y, Tsushima T, Imai T, Okumura K, Cancer 2001 91 964 971 10.1002/1097-0142(20010301)91:5<964::AID-CNCR1086>3.0.CO;2-O 11251948
9. The expression of transforming growth factor-beta1 is significantly correlated with the expression of vascular endothelial growth factor and poor prognosis of patients with advanced gastric carcinoma. Saito H, Tsujitani S, Oka S, Kondo A, Ikeguchi M, Maeta M, Kaibara N, Cancer 1999 86 1455 1462 10.1002/(SICI)1097-0142(19991015)86:8<1455::AID-CNCR11>3.0.CO;2-L 10526273 (Pubitemid 29489778)
10. Transforming growth factor beta 1 expression in human colorectal tumours: an independent prognostic marker in a subgroup of poor prognosis patients. Robson H, Anderson E, James RD, Schofield PF, Br J Cancer 1996 74 753 758 10.1038/bjc.1996.432 8795578 (Pubitemid 26300767)
11. Transforming growth factor-(beta)s and mammary gland involution; functional roles and implications for cancer progression. Flanders KC, Wakefield LM, J Mammary Gland Biol Neoplasia 2009 14 131 144 10.1007/s10911-009-9122-z 19396528
12. Tumor-derived TGF beta-1 induces dendritic cell apoptosis in the sentinel lymph node. Ito M, Minamiya Y, Kawai H, Saito S, Saito H, Nakagawa T, Imai K, Hirokawa M, Ogawa J, J Immunol 2006 176 5637 5643 16622033
13. Transforming growth factor-beta produced by progressor tumors inhibits, while IL-10 produced by regressor tumors enhances, Langerhans cell migration from skin. Halliday GM, Le S, Int Immunol 2001 13 1147 1154 10.1093/intimm/13.9. 1147 11526095 (Pubitemid 32899157)
14. Dendritic cells: making progress with tumour regression? Byrne SN, Halliday GM, Immunol Cell Biol 2002 80 520 530 10.1046/j.1440-1711.2002.01122.x 12406385 (Pubitemid 35335014)
15. TGFb1 inhibits the formation of benign skin tumors, but enhances progression to invasive spindle carcinomas in transgenic mice. Cui W, Fowlis DJ, Bryson S, Duffie E, Ireland H, Balmain A, Akhurst RJ, Cell 1996 86 531 542 10.1016/S0092-8674(00)80127-0 8752208 (Pubitemid 26299485)
16. Generation of tumor immunity by bone marrow-derived dendritic cells correlates with dendritic cell maturation stage. Labeur MS, Roters B, Pers B, Mehling A, Luger TA, Schwarz T, Grabbe S, J Immunol 1999 162 168 175 9886383 (Pubitemid 29018917)
17. Chemotactic response toward chemokines and its regulation by transforming growth factor-beta1 of murine bone marrow hematopoietic progenitor cell-derived different subset of dendritic cells. Ogata M, Zhang Y, Wang Y, Itakura M, Zhang YY, Harada A, Hashimoto S, Matsushima K, Blood 1999 93 3225 3232 10233873 (Pubitemid 29220888)
18. An elevated serum level of transforming growth factor-beta 1 (TGF-beta 1) significantly correlated with lymph node metastasis and poor prognosis in patients with gastric carcinoma. Saito H, Tsujitani S, Oka S, Kondo A, Ikeguchi M, Maeta M, Kaibara N, Anticancer Res 2000 20 4489 4493 11205293 (Pubitemid 32141808)
19. The dynamic roles of TGF- in cancer. Meulmeester E, Ten Dijke P, J Pathol 2011 223 205 218 20957627
20. Transforming growth factor-beta1 immobilises dendritic cells within skin tumours and facilitates tumour escape from the immune system. Weber F, Byrne SN, Le S, Brown DA, Breit SN, Scolyer RA, Halliday GM, Cancer Immunol Immunother 2005 54 898 906 10.1007/s00262-004-0652-3 15776284 (Pubitemid 40991332)
21. Roles of TGF beta in metastasis. Padua D, Massagué J, Cell Res 2009 19 89 102 10.1038/cr.2008.316 19050696
22. Loss of TGF-beta type II receptor in fibroblasts promotes mammary carcinoma growth and invasion through upregulation of TGF-alpha-, MSP-and HGF-mediated signaling networks. Cheng N, Bhowmick NA, Chytil A, Gorksa AE, Brown KA, Muraoka R, Arteaga CL, Neilson EG, Hayward SW, Moses HL, Oncogene 2005 24 5053 5068 10.1038/sj.onc.1208685 15856015 (Pubitemid 41129083)
23. Effect of conditional knockout of the type II TGF-beta receptor gene in mammary epithelia on mammary gland development and polyomavirus middle T antigen induced tumor formation and metastasis. Forrester E, Chytil A, Bierie B, Aakre M, Gorska AE, Sharif-Afshar AR, Muller WJ, Moses HL, Cancer Res 2005 65 2296 2302 10.1158/0008-5472.CAN-04-3272 15781643 (Pubitemid 40490139)
24. Abrogation of TGF beta signaling in mammary carcinomas recruits Gr-1+CD11b+ myeloid cells that promote metastasis. Yang L, Huang J, Ren X, Gorska AE, Chytil A, Aakre M, Carbone DP, Matrisian LM, Richmond A, Lin PC, Moses HL, Cancer Cell 2008 13 23 35 10.1016/j.ccr.2007.12.004 18167337 (Pubitemid 350309741)