-
1
-
-
67649440886
-
The biology of ovarian cancer: New opportunities for translation
-
Bast RJ, Hennessy B, and Mills G (2009). The biology of ovarian cancer: new opportunities for translation. Nat Rev Cancer 9, 415-428.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 415-428
-
-
Bast, R.J.1
Hennessy, B.2
Mills, G.3
-
2
-
-
79955834631
-
Metformin suppresses ovarian cancer growth and metastasis with enhancement of cisplatin cytotoxicity in vivo
-
Rattan R, Graham R, Maguire J, Giri S, and Shridhar V (2011). Metformin suppresses ovarian cancer growth and metastasis with enhancement of cisplatin cytotoxicity in vivo. Neoplasia 13, 483-491.
-
(2011)
Neoplasia
, vol.13
, pp. 483-491
-
-
Rattan, R.1
Graham, R.2
Maguire, J.3
Giri, S.4
Shridhar, V.5
-
3
-
-
73949092289
-
An orally available smallmolecule inhibitor of c-Met, PF-2341066, reduces tumor burden and metastasis in a preclinical model of ovarian cancer metastasis
-
Zillhardt M, Christensen J, and Lengyel E (2010). An orally available smallmolecule inhibitor of c-Met, PF-2341066, reduces tumor burden and metastasis in a preclinical model of ovarian cancer metastasis. Neoplasia 12, 1-10.
-
(2010)
Neoplasia
, vol.12
, pp. 1-10
-
-
Zillhardt, M.1
Christensen, J.2
Lengyel, E.3
-
4
-
-
79951501975
-
Macitentan (ACT-064992), a tissue-targeting endothelin receptor antagonist, enhances therapeutic efficacy of paclitaxel by modulating survival pathways in orthotopic models of metastatic human ovarian cancer
-
Kim S, Kim J, Kim S, Brantley E, Yun S, He J, Maya M, Zhang F, Wu Q, Lehembre F, et al. (2011). Macitentan (ACT-064992), a tissue-targeting endothelin receptor antagonist, enhances therapeutic efficacy of paclitaxel by modulating survival pathways in orthotopic models of metastatic human ovarian cancer. Neoplasia 13, 167-179.
-
(2011)
Neoplasia
, vol.13
, pp. 167-179
-
-
Kim, S.1
Kim, J.2
Kim, S.3
Brantley, E.4
Yun, S.5
He, J.6
Maya, M.7
Zhang, F.8
Wu, Q.9
Lehembre, F.10
-
5
-
-
79955865397
-
Identification of an exon 4-deletion variant of epidermal growth factor receptor with increased metastasis-promoting capacity
-
Wang H, Zhou M, Shi B, Zhang Q, Jiang H, Sun Y, Liu J, Zhou K, Yao M, Gu J, et al. (2011). Identification of an exon 4-deletion variant of epidermal growth factor receptor with increased metastasis-promoting capacity. Neoplasia 13, 461-471.
-
(2011)
Neoplasia
, vol.13
, pp. 461-471
-
-
Wang, H.1
Zhou, M.2
Shi, B.3
Zhang, Q.4
Jiang, H.5
Sun, Y.6
Liu, J.7
Zhou, K.8
Yao, M.9
Gu, J.10
-
6
-
-
78049526522
-
Role of chemokine network in the development and progression of ovarian cancer: A potential novel pharmacological target
-
2010, 426956
-
Barbieri F, Bajetto A, and Florio T (2010). Role of chemokine network in the development and progression of ovarian cancer: a potential novel pharmacological target. J Oncol 2010, 426956.
-
(2010)
J Oncol
-
-
Barbieri, F.1
Bajetto, A.2
Florio, T.3
-
7
-
-
33748548126
-
Expression of chemokine CXCL12 and its receptor CXCR4 in human epithelial ovarian cancer: An independent prognostic factor for tumor progression
-
Jiang Y, Wu X, Shi B, Wu W, and Yin G (2006). Expression of chemokine CXCL12 and its receptor CXCR4 in human epithelial ovarian cancer: an independent prognostic factor for tumor progression. Gynecol Oncol 103, 226-233.
-
(2006)
Gynecol Oncol
, vol.103
, pp. 226-233
-
-
Jiang, Y.1
Wu, X.2
Shi, B.3
Wu, W.4
Yin, G.5
-
8
-
-
0035393583
-
Epithelial cancer cell migration: A role for chemokine receptors?
-
Scotton C, Wilson J, Milliken D, Stamp G, and Balkwill F (2001). Epithelial cancer cell migration: a role for chemokine receptors? Cancer Res 61, 3.
-
(2001)
Cancer Res
, vol.61
, pp. 3
-
-
Scotton, C.1
Wilson, J.2
Milliken, D.3
Stamp, G.4
Balkwill, F.5
-
9
-
-
0035107880
-
Production of stromal cell-derived factor 1 by mesothelial cells and effects of this chemokine on peritoneal B lymphocytes
-
Foussat A, Balabanian K, Amara A, Bochet-Delbos L, Durand-Gasselin I, Baleux F, Couderc J, Galanaud P, and Emilie D (2001). Production of stromal cell-derived factor 1 by mesothelial cells and effects of this chemokine on peritoneal B lymphocytes. Eur J Immunol 31, 350-359.
-
(2001)
Eur J Immunol
, vol.31
, pp. 350-359
-
-
Foussat, A.1
Balabanian, K.2
Amara, A.3
Bochet-Delbos, L.4
Durand-Gasselin, I.5
Baleux, F.6
Couderc, J.7
Galanaud, P.8
Emilie, D.9
-
10
-
-
0037108923
-
Multiple actions of the chemokine CXCL12 on epithelial tumor cells in human ovarian cancer
-
Scotton C, Wilson J, Scott K, Stamp G, Wilbanks G, Fricker S, Bridger G, and Balkwill F (2002). Multiple actions of the chemokine CXCL12 on epithelial tumor cells in human ovarian cancer. Cancer Res 62, 5930-5938.
-
(2002)
Cancer Res
, vol.62
, pp. 5930-5938
-
-
Scotton, C.1
Wilson, J.2
Scott, K.3
Stamp, G.4
Wilbanks, G.5
Fricker, S.6
Bridger, G.7
Balkwill, F.8
-
11
-
-
35148893581
-
Stromal-cell derived factor-1 regulates epithelial ovarian cancer cell invasion by activating matrix metalloproteinase-9 and matrix metalloproteinase-2
-
Yuecheng Y and Xiaoyan X (2007). Stromal-cell derived factor-1 regulates epithelial ovarian cancer cell invasion by activating matrix metalloproteinase-9 and matrix metalloproteinase-2. Eur J Cancer Prev 16, 430-435.
-
(2007)
Eur J Cancer Prev
, vol.16
, pp. 430-435
-
-
Yuecheng, Y.1
Xiaoyan, X.2
-
12
-
-
78649700451
-
Involvement of autocrine CXCL12/CXCR4 system in the regulation of ovarian carcinoma cell invasion
-
Miyanishi N, Suzuki Y, Simizu S, Kuwabara Y, Banno K, and Umezawa K (2010). Involvement of autocrine CXCL12/CXCR4 system in the regulation of ovarian carcinoma cell invasion. Biochem Biophys Res Commun 403, 154-159.
-
(2010)
Biochem Biophys Res Commun
, vol.403
, pp. 154-159
-
-
Miyanishi, N.1
Suzuki, Y.2
Simizu, S.3
Kuwabara, Y.4
Banno, K.5
Umezawa, K.6
-
13
-
-
19944431949
-
CXCL12 and vascular endothelial growth factor synergistically induce neoangiogenesis in human ovarian cancers
-
Kryczek I, Lange A, Mottram P, Alvarez X, Cheng P, Hogan M, Moons L, Wei S, Zhou L, Machelon V, et al. (2005). CXCL12 and vascular endothelial growth factor synergistically induce neoangiogenesis in human ovarian cancers. Cancer Res 65, 465-472.
-
(2005)
Cancer Res
, vol.65
, pp. 465-472
-
-
Kryczek, I.1
Lange, A.2
Mottram, P.3
Alvarez, X.4
Cheng, P.5
Hogan, M.6
Moons, L.7
Wei, S.8
Zhou, L.9
Machelon, V.10
-
14
-
-
18844428327
-
Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion
-
Orimo A, Gupta P, Sgroi D, Arenzana-Seisdedos F, Delaunay T, Naeem R, Carey V, Richardson A, and Weinberg R (2005). Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion. Cell 121, 335-348.
-
(2005)
Cell
, vol.121
, pp. 335-348
-
-
Orimo, A.1
Gupta, P.2
Sgroi, D.3
Arenzana-Seisdedos, F.4
Delaunay, T.5
Naeem, R.6
Carey, V.7
Richardson, A.8
Weinberg, R.9
-
15
-
-
35448930176
-
Stromal cell-derived factor-1 promotes cell migration and tumor growth of colorectal metastasis
-
Kollmar O, Rupertus K, Scheuer C, Junker B, Tilton B, Schilling M, and Menger M (2007). Stromal cell-derived factor-1 promotes cell migration and tumor growth of colorectal metastasis. Neoplasia 9, 862-870.
-
(2007)
Neoplasia
, vol.9
, pp. 862-870
-
-
Kollmar, O.1
Rupertus, K.2
Scheuer, C.3
Junker, B.4
Tilton, B.5
Schilling, M.6
Menger, M.7
-
16
-
-
49049108182
-
Imaging CXCR4 signaling with firefly luciferase complementation
-
Luker K, Gupta M, and Luker G (2008). Imaging CXCR4 signaling with firefly luciferase complementation. Anal Chem 80, 5565-5573.
-
(2008)
Anal Chem
, vol.80
, pp. 5565-5573
-
-
Luker, K.1
Gupta, M.2
Luker, G.3
-
17
-
-
70149109363
-
Imaging liganddependent activation of CXCR7
-
Luker K, Gupta M, Steele J, Foerster B, and Luker G (2009). Imaging liganddependent activation of CXCR7. Neoplasia 11, 1022-1035.
-
(2009)
Neoplasia
, vol.11
, pp. 1022-1035
-
-
Luker, K.1
Gupta, M.2
Steele, J.3
Foerster, B.4
Luker, G.5
-
18
-
-
84855423710
-
-
Nat Med, E-pub ahead of print December 4
-
Luker K, Mihalko L, Schmidt B, Lewin S, Ray P, Shcherbo D, Chudakov D, Luker G (2011). In vivo imaging of ligand receptor binding with Gaussia luciferase complementation. Nat Med, E-pub ahead of print December 4.
-
(2011)
In Vivo Imaging of Ligand Receptor Binding With Gaussia Luciferase Complementation
-
-
Luker, K.1
Mihalko, L.2
Schmidt, B.3
Lewin, S.4
Ray, P.5
Shcherbo, D.6
Chudakov, D.7
Luker, G.8
-
19
-
-
77957673657
-
Near infrared fluorescent proteins
-
Shcherbo D, Shemiakina I, Ryabova A, Luker K, Schmidt B, Souslova E, Gorodnicheva T, Strukova L, Shidlovskiy K, Britanova O, et al. (2010). Near infrared fluorescent proteins. Nat Methods 7, 827-829.
-
(2010)
Nat Methods
, vol.7
, pp. 827-829
-
-
Shcherbo, D.1
Shemiakina, I.2
Ryabova, A.3
Luker, K.4
Schmidt, B.5
Souslova, E.6
Gorodnicheva, T.7
Strukova, L.8
Shidlovskiy, K.9
Britanova, O.10
-
20
-
-
77955657351
-
Constitutive and chemokinedependent internalization and recycling of CXCR7 in breast cancer cells to degrade chemokine ligands
-
Luker K, Steele J, Mihalko L, and Luker G (2010). Constitutive and chemokinedependent internalization and recycling of CXCR7 in breast cancer cells to degrade chemokine ligands. Oncogene 29, 4599-4610.
-
(2010)
Oncogene
, vol.29
, pp. 4599-4610
-
-
Luker, K.1
Steele, J.2
Mihalko, L.3
Luker, G.4
-
21
-
-
70149106504
-
Bioluminescent CXCL12 fusion protein for cellular studies of CXCR4 and CXCR7
-
Luker K, Gupta M, and Luker G (2009). Bioluminescent CXCL12 fusion protein for cellular studies of CXCR4 and CXCR7. Biotechniques 47, 625-632.
-
(2009)
Biotechniques
, vol.47
, pp. 625-632
-
-
Luker, K.1
Gupta, M.2
Luker, G.3
-
22
-
-
61449217021
-
Imaging chemokine receptor dimerization with firefly luciferase complementation
-
Luker K, Gupta M, and Luker G (2009). Imaging chemokine receptor dimerization with firefly luciferase complementation. FASEB J 23, 823-834.
-
(2009)
FASEB J
, vol.23
, pp. 823-834
-
-
Luker, K.1
Gupta, M.2
Luker, G.3
-
23
-
-
14044250981
-
Codon-optimized Gaussia luciferase cDNA for mammalian gene expression in culture and in vivo
-
Tannous B, Kim D, Fernandez J, Weissleder R, and Breakefield X (2005). Codon-optimized Gaussia luciferase cDNA for mammalian gene expression in culture and in vivo. Mol Ther 11, 435-443.
-
(2005)
Mol Ther
, vol.11
, pp. 435-443
-
-
Tannous, B.1
Kim, D.2
Fernandez, J.3
Weissleder, R.4
Breakefield, X.5
-
24
-
-
9244234390
-
CXCR4 regulates growth of both primary and metastatic breast cancer
-
Smith M, Luker K, Garbow J, Prior J, Jackson E, Piwnica-Worms D, and Luker G (2004). CXCR4 regulates growth of both primary and metastatic breast cancer. Cancer Res 64, 8604-8612.
-
(2004)
Cancer Res
, vol.64
, pp. 8604-8612
-
-
Smith, M.1
Luker, K.2
Garbow, J.3
Prior, J.4
Jackson, E.5
Piwnica-Worms, D.6
Luker, G.7
-
25
-
-
77952932498
-
Microenvironmental regulation of chemokine (C-X-C-motif) receptor 4 in ovarian carcinoma
-
Barbolina M, Kim M, Liu Y, Shepard J, Belmadani A, Miller R, Shea L, and Stack M (2010). Microenvironmental regulation of chemokine (C-X-C-motif) receptor 4 in ovarian carcinoma. Mol Cancer Res 8, 653-664.
-
(2010)
Mol Cancer Res
, vol.8
, pp. 653-664
-
-
Barbolina, M.1
Kim, M.2
Liu, Y.3
Shepard, J.4
Belmadani, A.5
Miller, R.6
Shea, L.7
Stack, M.8
-
26
-
-
33751208345
-
A highly sensitive protein-protein interaction assay based on Gaussia luciferase
-
Remy I and Michnick S (2006). A highly sensitive protein-protein interaction assay based on Gaussia luciferase. Nat Methods 3, 977-979.
-
(2006)
Nat Methods
, vol.3
, pp. 977-979
-
-
Remy, I.1
Michnick, S.2
-
27
-
-
0038681342
-
The bicyclam AMD3100 story
-
De Clercq E (2003). The bicyclam AMD3100 story. Nat Rev Drug Discov 2, 581-587.
-
(2003)
Nat Rev Drug Discov
, vol.2
, pp. 581-587
-
-
de Clercq, E.1
-
28
-
-
70349234110
-
Elucidation of CXCR7-mediated signaling events and inhibition of CXCR4-mediated tumor cell transendothelial migration by CXCR7 ligands
-
Zabel B, Wang Y, Lewen S, Berahovich R, Penfold M, Zhang P, Powers J, Summers B, Miao Z, Zhao N, et al. (2009). Elucidation of CXCR7-mediated signaling events and inhibition of CXCR4-mediated tumor cell transendothelial migration by CXCR7 ligands. J Immunol 183, 3204-3211.
-
(2009)
J Immunol
, vol.183
, pp. 3204-3211
-
-
Zabel, B.1
Wang, Y.2
Lewen, S.3
Berahovich, R.4
Penfold, M.5
Zhang, P.6
Powers, J.7
Summers, B.8
Miao, Z.9
Zhao, N.10
-
29
-
-
0037025357
-
A point mutation that confers constitutive activity to CXCR4 reveals that T140 is an inverse agonist and that AMD3100 and ALX40-4C are weak partial agonists
-
Zhang W, Navenot J, Haribabu B, Tamamura H, Hiramatu K, Omagari A, Pei G, Manfredi J, Fujii N, Broach J, et al. (2002). A point mutation that confers constitutive activity to CXCR4 reveals that T140 is an inverse agonist and that AMD3100 and ALX40-4C are weak partial agonists. J Biol Chem277, 24515-24521.
-
(2002)
J Biol Chem277
, pp. 24515-24521
-
-
Zhang, W.1
Navenot, J.2
Haribabu, B.3
Tamamura, H.4
Hiramatu, K.5
Omagari, A.6
Pei, G.7
Manfredi, J.8
Fujii, N.9
Broach, J.10
-
30
-
-
33644546367
-
Role of the CXCL12/CXCR4 axis in peritoneal carcinomatosis of gastric cancer
-
Yasumoto K, Koizumi K, Kawashima A, Saitoh Y, Arita Y, Shinohara K, Minami T, Nakayama T, Sakurai H, Takahashi Y, et al. (2006). Role of the CXCL12/CXCR4 axis in peritoneal carcinomatosis of gastric cancer. Cancer Res 66, 2181-2187.
-
(2006)
Cancer Res
, vol.66
, pp. 2181-2187
-
-
Yasumoto, K.1
Koizumi, K.2
Kawashima, A.3
Saitoh, Y.4
Arita, Y.5
Shinohara, K.6
Minami, T.7
Nakayama, T.8
Sakurai, H.9
Takahashi, Y.10
-
31
-
-
28544436109
-
The inflammatory cytokine tumor necrosis factor-α regulates chemokine receptor expression on ovarian cancer cells
-
Kulbe H, Hagemann T, Szlosarek P, Balkwill F, and Wilson J (2005). The inflammatory cytokine tumor necrosis factor-α regulates chemokine receptor expression on ovarian cancer cells. Cancer Res 65, 10355-10362.
-
(2005)
Cancer Res
, vol.65
, pp. 10355-10362
-
-
Kulbe, H.1
Hagemann, T.2
Szlosarek, P.3
Balkwill, F.4
Wilson, J.5
-
32
-
-
36749003738
-
Involvement of SDF-1α/CXCR4 axis in the enhanced peritoneal metastasis of epithelial ovarian carcinoma
-
Kajiyama H, Shibata K, Terauchi M, Ino K, Nawa A, and Kikkawa F (2008). Involvement of SDF-1α/CXCR4 axis in the enhanced peritoneal metastasis of epithelial ovarian carcinoma. Int J Cancer 122, 91-99.
-
(2008)
Int J Cancer
, vol.122
, pp. 91-99
-
-
Kajiyama, H.1
Shibata, K.2
Terauchi, M.3
Ino, K.4
Nawa, A.5
Kikkawa, F.6
-
33
-
-
30044438368
-
Intraperitoneal cisplatin and paclitaxel in ovarian cancer
-
Armstrong D, Bundy B, Wenzel L, Huang H, Baergen R, Lele S, Copeland L, Walker J, Burger R, and Group GO (2006). Intraperitoneal cisplatin and paclitaxel in ovarian cancer. N Engl J Med 354, 34-43.
-
(2006)
N Engl J Med
, vol.354
, pp. 34-43
-
-
Armstrong, D.1
Bundy, B.2
Wenzel, L.3
Huang, H.4
Baergen, R.5
Lele, S.6
Copeland, L.7
Walker, J.8
Burger, R.9
Group, G.O.10
-
34
-
-
0034120373
-
Pharmacokinetics and safety of AMD-3100, a novel antagonist of the CXCR-4 chemokine receptor, in human volunteers
-
Hendrix C, Flexner C, MacFarland R, Giandomenico C, Fuchs E, Redpath E, Bridger G, and Henson G (2000). Pharmacokinetics and safety of AMD-3100, a novel antagonist of the CXCR-4 chemokine receptor, in human volunteers. Antimicrob Agents Chemother 44, 1667-1673.
-
(2000)
Antimicrob Agents Chemother
, vol.44
, pp. 1667-1673
-
-
Hendrix, C.1
Flexner, C.2
Macfarland, R.3
Giandomenico, C.4
Fuchs, E.5
Redpath, E.6
Bridger, G.7
Henson, G.8
-
35
-
-
80051690814
-
CXCL12/CXCR4 blockade induces multimodal antitumor effects that prolong survival in an immunocompetent mouse model of ovarian cancer
-
Righi E, Kashiwagi S, Yuan J, Santosuosso M, Leblanc P, Ingraham R, Forbes B, Edelblute B, Collette B, Xing D, et al. (2011). CXCL12/CXCR4 blockade induces multimodal antitumor effects that prolong survival in an immunocompetent mouse model of ovarian cancer. Cancer Res 71, 5522-5534.
-
(2011)
Cancer Res
, vol.71
, pp. 5522-5534
-
-
Righi, E.1
Kashiwagi, S.2
Yuan, J.3
Santosuosso, M.4
Leblanc, P.5
Ingraham, R.6
Forbes, B.7
Edelblute, B.8
Collette, B.9
Xing, D.10
|