Differential function of lysophosphatidic acid receptors in cell proliferation and migration of neuroblastoma cells

Cancer Letters

Volumn 316, Issue 1, 2012, Pages 91-96

  Hayashi, Mai ^a   Okabe, Kyoko ^a   Kato, Kohei ^a   Okumura, Mai ^a   Fukui, Rie ^a   Fukushima, Nobuyuki ^a   Tsujiuchi, Toshifumi ^a  

^a KINKI UNIVERSITY   (Japan)

Author keywords

B103; LPA; LPA receptor; Neuroblastoma; Rat

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; LYSOPHOSPHATIDIC ACID RECEPTOR; LYSOPHOSPHATIDIC ACID RECEPTOR 1; LYSOPHOSPHATIDIC ACID RECEPTOR 2; LYSOPHOSPHATIDIC ACID RECEPTOR 3; RHO KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CARCINOGENESIS; CELL ACTIVITY; CELL ASSAY; CELL INVASION; CELL MIGRATION; CELL MOTILITY; CELL PROLIFERATION; COLONY FORMATION; CONTROLLED STUDY; NEUROBLASTOMA; NEUROBLASTOMA CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT;

ANIMALS; CELL GROWTH PROCESSES; CELL MOVEMENT; MUTATION; NEOPLASM INVASIVENESS; NEUROBLASTOMA; RATS; RECEPTORS, LYSOPHOSPHATIDIC ACID; TUMOR CELLS, CULTURED;

RATTUS;

EID: 84855457979     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2011.10.030     Document Type: Article

References (27)

1. Lin M-E., Herr D.R., Chun J. Lysophosphatidic acid (LPA) receptors: signaling properties and disease relevance. Prostaglandins Other Lipid Mediat. 2010, 91:130-138.
2. Aoki J., Inoue A., Okudaira S. Two pathway for lysophosphatidic acid production. Biochim. Biophys. Acta 2008, 1781:513-518.
3. Ishii I., Fukushima N., Ye X., Chun J. Lysophospholipid receptors: signaling and biology. Annu. Rev. Biochem. 2004, 73:321-354.
4. Furui T., LaPushin R., Mao M., Khan H., Watt S.R., Watt M.A.V. Overexpression of Edg-2/vzg-1 Induces apoptosis and anoikis in ovarian cancer cells in a lysophosphatidic acid-independent manner. Clinical Cancer Res. 1999, 5:4308-4318.
5. Fang X., Schummer M., Mao M., Yu S., Tabassam F.H., Swaby R., Hasegawa Y., Tanyi J.L., LaPushin R., Eder A., Jaffe R., Erickson J., Mills G.B. Lysophosphatidic acid is a bioactive mediator in ovarian cancer. Biochim. Biophys. Acta 2002, 1582:257-264.
6. Fujita T., Miyamoto S., Onoyama I., Sonoda K., Mekada E., Nakano H. Expression of lysophosphatidic acid receptors and vascular endothelial growth factor mediating lysophosphatidic acid in the development of human ovarian cancer. Cancer Lett. 2003, 192:161-169.
7. Goetzl E.J., Dolezalova H., Kong Y., Hu Y.L., Jaffe R.B., Kalli K.R., Conover C.A. Distinctive expression and functions of the type 4 endothelial differentiation gene-encoded G protein-coupled receptor for lysophosphatidic acid in ovarian cancer. Cancer Res. 1999, 59:5370-5375.
8. Shida D., Watanabe T., Aoki J., Hama K., Kitayama J., Sonoda H., Kishi Y., Yamaguchi H., Sasaki S., Sako A., Konishi T., Arai H., Nagawa H. Aberrant expression of lysophosphatidic acid (LPA) receptors in human colorectal cancer. Lab. Investigation 2004, 84:1352-1362.
9. Schulte K.M., Beyer A., Kohrer K., Oberhauser S., Roher H.D., acid Lysophosphatidic a novel lipid growth factor for human thyroid cells: over-expression of the high-affinity receptor edg4 in differentiated thyroid cancer. Int. J. Cancer 2001, 92:249-256.
10. Tsujiuchi T., Shimizu K., Onishi M., Sugata E., Fujii H., Mori T., Honoki K., Fukushima N. Involvement of aberrant DNA methylation on reduced expression of lysophosphatidic acid receptor-1 gene in rat tumor cell lines. Biochem. Biophys. Res. Commun. 2006, 349:1151-1155.
11. Okabe K., Hayashi M., Wakabayashi N., Yamawaki Y., Teranishi M., Fukushima N., Tsujiuchi T. Different expressions and DNA methylation patterns of lysophosphatidic acid receptor genes in mouse tumor cells. Pathobiology 2010, 77:278-282.
12. Tsujino M., Fujii M., Okabe K., Mori T., Fukushima N., Tsujiuchi T. Differential expressions and DNA methylation patterns of lysophosphatidic acid receptor genes in human colon cancer cells. Virchows Arch. 2010, 457:669-676.
13. Yamada T., Furukawa M., Hotta M., Yamasaki A., Honoki K., Fukushima N., Tsujiuchi T. Mutations of lysophosphatidic acid receptor-1 gene during progression of lung tumors in rats. Biochem. Biophys. Res. Commun. 2009, 378:424-427.
14. Obo Y., Yamada T., Furukawa M., Hotta M., Honoki K., Fukushima N., Tsujiuchi T. Frequent mutations of lysophosphatidic acid receptor-1 gene in rat liver tumors. Mutat. Res. 2009, 660:47-50.
15. A1 /edg-2 couples to G proteins and mediates multiple cellular responses to lysophosphatidic acid. Proc. Natl. Acad. Sci. USA 1998, 95:6151-6156.
16. A3/EDG-7 in nueral cell lines using a retrovirus expression system. Mol. Pharmacol. 2000, 58:895-902.
17. 9/GPR23 mediates Rho-dependent morphological changes in a rat neural cell line. J. Biol. Chem. 2007, 282:5814-5824.
18. Sayas C.L., Ariaens A., Ponsionen B., Moolenaar W.H. GSK-3 is activated by the tyrosine kinase Pyk2 during LPA1-mediated neurite retraction. Mol. Biol. Cell. 2006, 17:1834-1844.
19. Shano S., Hatanaka K., Ninose S., Moriyama R., Tsujiuchi T., Fukushima N. A Lysophosphatidic acid receptor lacking the PDZ-binding domain is constitutively active and stimulates cell proliferation. Biochim. Biophys. Acta 2008, 1783:748-759.
20. Shida D., Kitayama J., Yanaguchi H., Okaji Y., Tsuno N.H., Watanabe T., Takuwa Y., Nagawa H. Lysophosphatidic acid (LPA) enhances the metastatic potential of human colon carcinoma DLD1 cells through LPA1. Cancer Res. 2003, 63:1706-1711.
21. Yu S., Murph M.M., Lu Y., liu S., Hall H.S., Liu J., Stephens C., Fang X., Mills G.B. Lysophosphatidic acid receptors determine tumorigenicity and aggressiveness of ovarian cancer cells. J. Natl. Cancer Inst. 2008, 100:1630-1642.
22. Park S.Y., Jeong K.J., Panupinthu N., Yu S., Lee J., Han J.W., Kim J.M., Lee J-S., Kang J., Park C.G., Mills G.B., Lee H.Y. Lysophosphatidic acid augments human hepatocellular carcinoma cell invasion through LPA1 receptor and MMP-9 expression. Oncogene 2011, 30:1351-1359.
23. Hayashi M., Okabe K., Yamawaki Y., Teranishi M., Honoki K., Mori T., Fukushima N., Tsujiuchi T., Biochem Loss of lysophosphatidic acid receptor-3 enhances cell migration in rat lung tumor cells. Biophys. Res. Commun. 2011, 405:450-454.
24. Okabe K., Kato K., Teranishi M., Okumura M., Fukui R., Mori T., Fukushima N., Tsujiuchi T. Induction of lysophosphatidic acid receptor-3 by 12-O-tetradecanoylphorbol-13-acetate stimulates cell migration of rat liver cells. Cancer Lett 2011, 309:236-242.
25. /11-selective inhibitor. J. Biol. Chem. 2004, 279:47438-47445.
26. Tsujiuchi T., Furukawa M., Yamasaki A., Hotta M., Kusunoki C., Suyama N., Mori T., Honoki K., Fukushima N. Infrequent mutation of lysophosphatidic acid receptor-1 gene in hamster pancreatic duct adenocarcinomas and established cell lines. J. Toxicol. Pathol. 2009, 22:89-92.
27. Murph M.M., Nguyen G.H., Radhakrishna H., Mills G.B. Sharpening the edges of understanding the structure/function of the LPA1 receptor: expression in cancer and mechanisms of regulation. Biochim. Biophys. Acta 2008, 1781:547-557.