Determination of trace amount of enantiomeric impurity in therapeutic nicotine derivative using capillary electrophoresis with new imaging technology detection

Journal of Separation Science

Volumn 35, Issue 1, 2012, Pages 66-72

  Dahab, Ali A ^a   Smith, Norman W ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Chiral separation; Enantiomeric impurities; Highly sulphated cyclodextrin; Label free intrinsic imaging

Indexed keywords

BACK GROUND ELECTROLYTE; BASELINE SEPARATION; CARRIER PROTEINS; CHIRAL MOLECULE; CHIRAL SELECTOR; CHIRAL SEPARATIONS; DETECTION LIMITS; ENANTIOMERIC PURITY; ENANTIOSEPARATIONS; FUSED-SILICA CAPILLARIES; IMAGING TECHNOLOGY; LABEL FREE; REGULATORY AUTHORITIES; TOBACCO SMOKING; TRACE AMOUNTS; UV DETECTION;

BUTYRIC ACID; CAPILLARY ELECTROPHORESIS; CHEMICAL DETECTION; CHIRALITY; FATTY ACIDS; FUSED SILICA; IMAGING TECHNIQUES; IMPURITIES; PHOSPHORIC ACID; PYRIDINE; SEPARATION; STEREOCHEMISTRY; TRACE ANALYSIS;

ENANTIOMERS;

BETA CYCLODEXTRIN DERIVATIVE; BUTYRIC ACID DERIVATIVE; ELECTROLYTE; NICOTINE BUTYRIC ACID; NICOTINE DERIVATIVE; PHOSPHORIC ACID; SULFATED BETA CYCLODEXTRIN; TRIETHYLAMINE; UNCLASSIFIED DRUG;

ARTICLE; CAPILLARY ELECTROPHORESIS; ENANTIOMER; IMAGING SYSTEM; PH MEASUREMENT; PRIORITY JOURNAL; ULTRAVIOLET RADIATION;

BUTYRIC ACID; DRUG CONTAMINATION; ELECTROPHORESIS, CAPILLARY; HUMANS; NICOTINE; STEREOISOMERISM; TOBACCO USE DISORDER;

NICOTIANA TABACUM;

EID: 84855438935     PISSN: 16159306     EISSN: 16159314     Source Type: Journal    
DOI: 10.1002/jssc.201100513     Document Type: Article

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