Stereoselective metabolism of nicotine and tobacco-specific N- nitrosamines to 4-hydroxy-4-(3-pyridyl)butanoic acid in rats

Chemical Research in Toxicology

Volumn 12, Issue 2, 1999, Pages 164-171

  Trushin, Neil ^a   Hecht, Stephen S ^b  

^a AMERICAN HEALTH FOUNDATION   (United States)

^b UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BUTYRIC ACID DERIVATIVE; CIGARETTE SMOKE; NICOTINE; NITROSAMINE;

ANIMAL EXPERIMENT; ARTICLE; CHIRALITY; CONTROLLED STUDY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; NONHUMAN; RAT; SMOKING; STEREOCHEMISTRY; TOXICOKINETICS; URINALYSIS;

ANIMALS; BIOTRANSFORMATION; CARCINOGENS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HUMANS; HYDROXYBUTYRATES; HYDROXYLATION; MALE; MICROSOMES, LIVER; NICOTINE; NITROSAMINES; PYRIDINES; RATS; RATS, INBRED F344; STEREOISOMERISM;

ANIMALIA; NICOTIANA TABACUM; RODENTIA;

EID: 0033010821     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx980213q     Document Type: Article

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