Disruption of alternative NAD(P)H dehydrogenases leads to decreased mitochondrial ROS in Neurospora crassa

Free Radical Biology and Medicine

Volumn 52, Issue 2, 2012, Pages 402-409

  Carneiro, Patrícia ^a   Duarte, Margarida ^a   Videira, Arnaldo ^a,b  

^a UNIVERSITY OF PORTO   (Portugal)

^b UNIVERSITY OF PORTO   (Portugal)

Author keywords

Free radicals; Mitochondria; NAD(P)H dehydrogenase; Neurospora crassa; Paraquat; Reactive oxygen species; Respiratory mutant

Indexed keywords

OXIDOREDUCTASE; PARAQUAT; REACTIVE OXYGEN METABOLITE; SCAVENGER;

ARTICLE; CONTROLLED STUDY; ENZYME DENATURATION; FUNGAL GENE; FUNGUS MUTANT; MITOCHONDRIAL RESPIRATION; MITOCHONDRION; NEUROSPORA CRASSA; NONHUMAN; PRIORITY JOURNAL;

CATALASE; GENE EXPRESSION; HYDROGEN PEROXIDE; MITOCHONDRIA; NADPH DEHYDROGENASE; NEUROSPORA CRASSA; OXIDANTS; OXIDATIVE STRESS; PARAQUAT; PHENOTYPE; PROTOZOAN PROTEINS; REACTIVE OXYGEN SPECIES; SUPEROXIDE DISMUTASE; UP-REGULATION;

NEUROSPORA; NEUROSPORA CRASSA;

EID: 84855438617     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2011.10.492     Document Type: Article

References (60)

1. A. Videira, and M. Duarte From NADH to ubiquinone in Neurospora mitochondria Biochim. Biophys. Acta 1555 2002 187 191 (Pubitemid 35246026)
2. A.M. Melo, T.M. Bandeiras, and M. Teixeira New insights into type II NAD(P)H:quinone oxidoreductases Microbiol. Mol. Biol. Rev. 68 2004 603 616 (Pubitemid 39628528)
3. A.G. Rasmusson, D.A. Geisler, and I.M. Moller The multiplicity of dehydrogenases in the electron transport chain of plant mitochondria Mitochondrion 8 2008 47 60 (Pubitemid 350263739)
4. M.P. Murphy How mitochondria produce reactive oxygen species Biochem. J. 417 2009 1 13
5. A.J. Kowaltowski, N.C. de Souza-Pinto, R.F. Castilho, and A.E. Vercesi Mitochondria and reactive oxygen species Free Radic. Biol. Med. 47 2009 333 343
6. M.L. Circu, and T.Y. Aw Reactive oxygen species, cellular redox systems, and apoptosis Free Radic. Biol. Med. 48 2010 749 762
7. Y.J. Suzuki, H.J. Forman, and A. Sevanian Oxidants as stimulators of signal transduction Free Radic. Biol. Med. 22 1997 269 285 (Pubitemid 26399334)
8. H. Zhang, Y.M. Go, and D.P. Jones Mitochondrial thioredoxin-2/ peroxiredoxin-3 system functions in parallel with mitochondrial GSH system in protection against oxidative stress Arch. Biochem. Biophys. 465 2007 119 126 (Pubitemid 47283985)
9. 2 removal in brain mitochondria via the thioredoxin/peroxiredoxin system J. Biol. Chem. 285 2010 27850 27858
10. M. Zamocky, P.G. Furtmüller, and C. Obinger Evolution of catalases from bacteria to humans Antioxid. Redox Signal. 10 2008 1527 1548
11. B.T. Olesen, J. Clausen, and O. Vang Characterization of the transcriptional profile in primary astrocytes after oxidative stress induced by paraquat Neurotoxicology 29 2008 13 21
12. S.J. Ralph, S. Rodríguez-Enríquez, J. Neuzil, E. Saavedra, and R. Moreno-Sánchez The causes of cancer revisited: "mitochondrial malignancy" and ROS-induced oncogenic transformation-why mitochondria are targets for cancer therapy Mol. Aspects Med. 31 2010 145 170
13. B. Bandy, and A.J. Davison Mitochondrial mutations may increase oxidative stress: implications for carcinogenesis and aging? Free Radic. Biol. Med. 8 1990 523 539 (Pubitemid 20204417)
14. R.S. Balaban, S. Nemoto, and T. Finkel Mitochondria, oxidants and aging Cell 120 2005 483 495
15. E. Naik, and V.M. Dixit Mitochondrial reactive oxygen species drive proinflammatory cytokine production J. Exp. Med. 208 2011 417 420
16. V. Adam-Vizi, and C. Chinopoulos Bioenergetics and the formation of mitochondrial reactive oxygen species Trends Pharmacol. Sci. 27 2006 639 645 (Pubitemid 44767940)
17. L.A. Esposito, S. Melov, A. Panov, B.A. Cottrell, and D.C. Wallace Mitochondrial disease in mouse results in increased oxidative stress Proc. Natl. Acad. Sci. U. S. A. 96 1999 4820 4825 (Pubitemid 29214495)
18. V. Adam-Vizi Production of reactive oxygen species in brain mitochondria: contribution by electron transport chain and non-electron transport chain sources Antioxid. Redox Signal. 7 2005 1140 1149 (Pubitemid 41232509)
19. H. Fukui, and C.T. Moraes The mitochondrial impairment, oxidative stress and neurodegeneration connection: reality or just an attractive hypothesis? Trends Neurosci. 31 2008 251 256
20. A.J. Lambert, and M.D. Brand Inhibitors of the quinine binding site allow rapid superoxide production from mitochondrial NADH:ubiquinone oxidoreductase (complex I) J. Biol. Chem. 279 2004 39414 39420 (Pubitemid 39258206)
21. J. Hirst, M.S. King, and K.R. Pryde The production of reactive oxygen species by complex I Biochem. Soc. Trans. 36 2008 976 980
22. Q. Chen, E.J. Vazquez, S. Moghaddas, C.L. Hoppel, and E.J. Lesnefsky Production of reactive oxygen species by mitochondria: central role of complex III J. Biol. Chem. 278 2003 36027 36031 (Pubitemid 37139922)
23. S. Dröse, and U. Brandt The mechanism of mitochondrial superoxide production by the cytochrome bc1 complex J. Biol. Chem. 283 2008 21649 21654
24. 2 signaling Antioxid. Redox Signal. 14 2011 459 468
25. B.B. Seo, M. Marella, T. Yagi, and A. Matsuno-Yagi The single subunit NADH dehydrogenase reduces generation of reactive oxygen species from complex I FEBS Lett. 580 2006 6105 6108 (Pubitemid 44666792)
26. A. Sanz, M. Soikkelia, M. Portero-Otínb, A. Wilsona, E. Kemppainena, G. McIlroya, S. Elliläa, K.K. Kemppainena, T. Tuomelaa, M. Lakanmaaa, E. Kivirantaa, R. Stefanatosa, E. Dufoura, B. Hutza, A. Naudíb, M. Jovéb, A. Zeba, S. Vartiainena, A. Matsuno-Yagic, T. Yagic, P. Rustind, R. Pamplonab, and H.T. Jacobs Expression of the yeast NADH dehydrogenase Ndi1 in Drosophila confers increased lifespan independently of dietary restriction Proc. Natl. Acad. Sci. U. S. A. 107 2010 9105 9110
27. S. Bahadorani, J. Cho, T. Lo, H. Contreras, H.O. Lawal, D.E. Krantz, T.J. Bradley, and D.W. Walker Neuronal expression of a single-subunit yeast NADH-ubiquinone oxidoreductase (Ndi1) extends Drosophila lifespan Aging Cell 9 2010 191 202
28. J. Fang, and D.S. Beattie External alternative NADH dehydrogenase of Saccharomyces cerevisiae: a potential source of superoxide Free Radic. Biol. Med. 34 2003 478 488 (Pubitemid 36140172)
29. D.A. Drechsel, and M. Patel Paraquat-induced production of reactive oxygen species in brain mitochondria Methods Enzymol. 456 2009 381 393
30. H.M. Cochemé, and M.P. Murphy Complex I is the major site of mitochondrial superoxide production by paraquat J. Biol. Chem. 283 2008 1786 1798
31. A.M. Melo, M. Duarte, and A. Videira Primary structure and characterisation of a 64 kDa NADH dehydrogenase from the inner membrane of Neurospora crassa mitochondria Biochim. Biophys. Acta 1412 1999 282 287 (Pubitemid 29356108)
32. M. Duarte, M. Peters, U. Schulte, and A. Videira The internal alternative NADH dehydrogenase of Neurospora crassa mitochondria Biochem. J. 37 2003 1005 1011 (Pubitemid 36578900)
33. P. Carneiro, M. Duarte, and A. Videira The main external alternative NAD(P)H dehydrogenase of Neurospora crassa mitochondria Biochim. Biophys. Acta 1608 2004 45 52 (Pubitemid 38115118)
34. P. Carneiro, M. Duarte, and A. Videira The external alternative NAD(P)H dehydrogenase NDE3 is localized both in the mitochondria and in the cytoplasm of Neurospora crassa J. Mol. Biol. 368 2007 1114 1121 (Pubitemid 46574668)
35. A.M. Melo, M. Duarte, I.M. Møller, H. Prokisch, P.L. Dolan, L. Pinto, M.A. Nelson, and A. Videira The external calcium-dependent NADPH dehydrogenase from Neurospora crassa mitochondria J. Biol. Chem. 276 2001 3947 3955
36. K. McCluskey The Fungal Genetics Stock Center: from molds to molecules Adv. Appl. Microbiol. 52 2003 245 262 (Pubitemid 37012800)
37. M. Westergaard, and H.K. Mitchell Neurospora. V. A synthetic medium favoring sexual reproduction Am. J. Bot. 34 1947 573 577
38. R.H. Davis, and F.J. de Serres Genetic and microbiological research techniques for Neurospora crassa Methods Enzymol. 17A 1970 79 143
39. M. Degli Esposti Measuring mitochondrial reactive oxygen species Methods 26 2002 335 340 (Pubitemid 34971573)
40. R. Fato, C. Bergaminia, M. Bortolus, A.L. Maniero, S. Leoni, T. Ohnishi, and G. Lenaz Differential effects of mitochondrial complex I inhibitors on production of reactive oxygen species Biochim. Biophys. Acta 1787 2009 384 392
41. H. Schägger Blue-native gels to isolate protein complexes from mitochondria Methods Cell Biol. 65 2001 231 244
42. L. Flohé, and F. Otting Superoxide dismutase assays Methods Enzymol. 105 1984 93 104 (Pubitemid 14165376)
43. S. Michán, F. Lledías, J.D. Baldwin, D.O. Natvig, and W. Hansberg Regulation and oxidation of two large monofunctional catalases Free Radic. Biol. Med. 33 2002 521 532 (Pubitemid 34874973)
44. W. Fecke, V.D. Sled, T. Ohnishi, and H. Weiss Disruption of the gene encoding the NADH-binding subunit of NADH:ubiquinone oxidoreductase in Neurospora crassa: formation of a partially assembled enzyme without FMN and the iron-sulphur cluster N-3 Eur. J. Biochem. 220 1994 551 558 (Pubitemid 24092823)
45. A. Castro, C. Lemos, A. Falcão, A.S. Fernandes, N.L. Glass, and A. Videira Rotenone enhances the antifungal properties of staurosporine Eukaryot. Cell 9 2010 906 914
46. P.R. Castello, D.A. Drechsel, and M. Patel Mitochondria are a major source of paraquat-induced reactive oxygen species production in the brain J. Biol. Chem. 282 2007 14186 14193 (Pubitemid 47100444)
47. J. Peng, M.L. Oo, and J.K. Andersen Synergistic effects of environmental risk factors and gene mutations in Parkinson's disease accelerate age-related neurodegeneration J. Neurochem. 115 2010 1363 1373
48. S.E. Schriner, A. Abrahamyan, A. Avanessian, I. Bussel, S. Maler, M. Gazarian, M.A. Holmbeck, and M. Jafari Decreased mitochondrial superoxide levels and enhanced protection against paraquat in Drosophila melanogaster supplemented with Rhodiola rósea Free Radic. Res. 43 2009 836 843
49. M. González-Guerrero, E. Oger, K. Benabdellah, C. Azcón-Aguilar, L. Lanfranco, and N. Ferrol Characterization of a CuZn superoxide dismutase gene in the arbuscular mycorrhizal fungus Glomus intraradices Curr. Genet. 56 2010 265 274
50. M. Salvi, V. Battaglia, A.M. Brunati, N. La Rocca, E. Tibaldi, P. Pietrangeli, L. Marcocci, B. Mondovi, C.A. Rossi, and A. Toninello Catalase takes part in rat liver mitochondria oxidative stress defense J. Biol. Chem. 282 2007 24407 24415 (Pubitemid 47328021)
51. V.Y. Petrova, D. Drescher, A.V. Kujumdzieva, and M.J. Schmitt Dual targeting of yeast catalase A to peroxisomes and mitochondria Biochem. J. 380 2004 393 400 (Pubitemid 38788110)
52. R.J. Mockett, A.C. Bayne, L.K. Kwong, W.C. Orr, and R.S. Sohal Ectopic expression of catalase in Drosophila mitochondria increases stress resistance but not longevity Free Radic. Biol. Med. 34 2003 207 217 (Pubitemid 36084324)
53. S.E. Schriner, N.J. Linford, G.M. Martin, P. Treuting, C.E. Ogburn, M. Emond, P.E. Coskun, W. Ladiges, N. Wolf, H. Van Remmen, D.C. Wallace, and P.S. Rabinovitch Extension of murine life span by overexpression of catalase targeted to mitochondria Science 308 2005 1909 1911 (Pubitemid 40941874)
54. I.O. Zubovych, S. Straud, and M.G. Roth Mitochondrial dysfunction confers resistance to multiple drugs in Caenorhabditis elegans Mol. Biol. Cell 6 2010 956 969
55. M.J. Falk, Z. Zhang, J.R. Rosenjack, I. Nissim, E. Daikhin, M.M. Sedensky, M. Yudkoff, and P.G. Morgan Metabolic pathway profiling of mitochondrial respiratory chain mutants in C. elegans Mol. Genet. Metab. 93 2008 388 397
56. Z. Liu, and R.A. Butow A transcriptional switch in the expression of yeast tricarboxylic acid cycle genes in response to a reduction or loss of respiratory function Mol. Cell. Biol. 19 1999 6720 6728 (Pubitemid 29441856)
57. J.S. Park, Y. Li, and Y. Bai Yeast NDI1 improves oxidative phosphorylation capacity and increases protection against oxidative stress and cell death in cells carrying a Leber's hereditary optic neuropathy mutation Biochim. Biophys. Acta 1772 2007 533 542 (Pubitemid 46589981)
58. B.B. Seo, E. Nakamaru-Ogiso, T.R. Flotte, A. Matsuno-Yagi, and T. Yagi In vivo complementation of complex I by the yeast Ndi1 enzyme: possible application for treatment of Parkinson disease J. Biol. Chem. 281 2006 14250 14255 (Pubitemid 43848352)
59. J. Barber-Singh, B.B. Seo, E. Nakamaru-Ogiso, Y.S. Lau, A. Matsuno-Yagi, and T. Yagi Neuroprotective effect of long-term NDI1 gene expression in a chronic mouse model of Parkinson disorder Rejuvenation Res. 12 2009 259 267
60. M. Marella, B.B. Seo, B.B. Thomas, A. Matsuno-Yagi, and T. Yagi Successful amelioration of mitochondrial optic neuropathy using the yeast NDI1 gene in a rat animal model PLoS One 5 2010 e11472