메뉴 건너뛰기




Volumn 71, Issue 3, 2012, Pages 214-223

Hypocretin/orexin signaling in the hypothalamic paraventricular nucleus is essential for the expression of nicotine withdrawal

Author keywords

Hypocretin; nicotine; PVN; SB334867; TCSOX229; withdrawal

Indexed keywords

1 (2 METHYL 6 BENZOXAZOLYL) 3 (1,5 NAPHTHYRIDIN 4 YL)UREA; AGENTS INTERACTING WITH TRANSMITTER, HORMONE OR DRUG RECEPTORS; MECAMYLAMINE; MICROSPHERE; NICOTINE; OREXIN; OREXIN 1 RECEPTOR; PROTEIN C FOS; RHODAMINE; TCSOX 229; UNCLASSIFIED DRUG;

EID: 84855427935     PISSN: 00063223     EISSN: 18732402     Source Type: Journal    
DOI: 10.1016/j.biopsych.2011.06.025     Document Type: Article
Times cited : (76)

References (60)
  • 1
    • 65249154248 scopus 로고    scopus 로고
    • Pharmacology of nicotine: Addiction, smoking-induced disease, and therapeutics
    • N.L. Benowitz Pharmacology of nicotine: Addiction, smoking-induced disease, and therapeutics Annu Rev Pharmacol Toxicol 49 2009 57 71
    • (2009) Annu Rev Pharmacol Toxicol , vol.49 , pp. 57-71
    • Benowitz, N.L.1
  • 2
    • 38149057528 scopus 로고    scopus 로고
    • Craving, withdrawal, and smoking urges on days immediately prior to smoking relapse
    • S.S. Allen, T. Bade, D. Hatsukami, B. Center Craving, withdrawal, and smoking urges on days immediately prior to smoking relapse Nicotine Tob Res 10 2008 35 45
    • (2008) Nicotine Tob Res , vol.10 , pp. 35-45
    • Allen, S.S.1    Bade, T.2    Hatsukami, D.3    Center, B.4
  • 4
    • 33947182514 scopus 로고    scopus 로고
    • Effects of abstinence from tobacco: Valid symptoms and time course
    • DOI 10.1080/14622200701188919, PII 772841444
    • J.R. Hughes Effects of abstinence from tobacco: Valid symptoms and time course Nicotine Tob Res 9 2007 315 327 (Pubitemid 46404264)
    • (2007) Nicotine and Tobacco Research , vol.9 , Issue.3 , pp. 315-327
    • Hughes, J.R.1
  • 6
    • 0036800871 scopus 로고    scopus 로고
    • Lack of CB1 cannabinoid receptors modifies nicotine behavioural responses, but not nicotine abstinence
    • DOI 10.1016/S0028-3908(02)00118-1, PII S0028390802001181
    • A. Castaé, E. Valjent, C. Ledent, M. Parmentier, R. Maldonado, O. Valverde Lack of CB1 cannabinoid receptors modifies nicotine behavioural responses, but not nicotine abstinence Neuropharmacology 43 2002 857 867 (Pubitemid 35221396)
    • (2002) Neuropharmacology , vol.43 , Issue.5 , pp. 857-867
    • Castane, A.1    Valjent, E.2    Ledent, C.3    Parmentier, M.4    Maldonado, R.5    Valverde, O.6
  • 7
    • 41149089252 scopus 로고    scopus 로고
    • Differential role of nicotinic acetylcholine receptor subunits in physical and affective nicotine withdrawal signs
    • DOI 10.1124/jpet.107.132977
    • K.J. Jackson, B.R. Martin, J.P. Changeux, M.I. Damaj Differential role of nicotinic acetylcholine receptor subunits in physical and affective nicotine withdrawal signs J Pharmacol Exp Ther 325 2008 302 312 (Pubitemid 351439184)
    • (2008) Journal of Pharmacology and Experimental Therapeutics , vol.325 , Issue.1 , pp. 302-312
    • Jackson, K.J.1    Martin, B.R.2    Changeux, J.P.3    Damaj, M.I.4
  • 8
    • 44649184948 scopus 로고    scopus 로고
    • Decreased brain reward function during nicotine withdrawal in C57BL6 mice: Evidence from intracranial self-stimulation (ICSS) studies
    • P.M. Johnson, J.A. Hollander, P.J. Kenny Decreased brain reward function during nicotine withdrawal in C57BL6 mice: Evidence from intracranial self-stimulation (ICSS) studies Pharmacol Biochem Behav 90 2008 409 415
    • (2008) Pharmacol Biochem Behav , vol.90 , pp. 409-415
    • Johnson, P.M.1    Hollander, J.A.2    Kenny, P.J.3
  • 9
    • 77956465568 scopus 로고    scopus 로고
    • Neurobiological mechanisms involved in nicotine dependence and reward: Participation of the endogenous opioid system
    • F. Berrendero, P. Robledo, J.M. Trigo, E. Martín-García, R. Maldonado Neurobiological mechanisms involved in nicotine dependence and reward: Participation of the endogenous opioid system Neurosci Biobehav Rev 35 2010 220 231
    • (2010) Neurosci Biobehav Rev , vol.35 , pp. 220-231
    • Berrendero, F.1    Robledo, P.2    Trigo, J.M.3    Martín-García, E.4    Maldonado, R.5
  • 10
    • 63849115116 scopus 로고    scopus 로고
    • Nicotinic receptors in the habenulo-interpeduncular system are necessary for nicotine withdrawal in mice
    • R. Salas, R. Sturm, J. Boulter, M. De Biasi Nicotinic receptors in the habenulo-interpeduncular system are necessary for nicotine withdrawal in mice J Neurosci 29 2009 3014 3018
    • (2009) J Neurosci , vol.29 , pp. 3014-3018
    • Salas, R.1    Sturm, R.2    Boulter, J.3    De Biasi, M.4
  • 13
    • 77954566931 scopus 로고    scopus 로고
    • The orexin system: Roles in sleep/wake regulation
    • T. Sakurai, M. Mieda, N. Tsujino The orexin system: Roles in sleep/wake regulation Ann N Y Acad Sci 1200 2010 149 161
    • (2010) Ann N y Acad Sci , vol.1200 , pp. 149-161
    • Sakurai, T.1    Mieda, M.2    Tsujino, N.3
  • 14
    • 77954948437 scopus 로고    scopus 로고
    • Hypocretins in the control of sleep and wakefulness
    • P. Bonnavion, L. de Lecea Hypocretins in the control of sleep and wakefulness Curr Neurol Neurosci Rep 10 2010 174 179
    • (2010) Curr Neurol Neurosci Rep , vol.10 , pp. 174-179
    • Bonnavion, P.1    De Lecea, L.2
  • 16
    • 69049101933 scopus 로고    scopus 로고
    • Hypocretin mechanisms in nicotine addiction: Evidence and speculation
    • W.A. Corrigall Hypocretin mechanisms in nicotine addiction: Evidence and speculation Psychopharmacology (Berl) 206 2009 23 37
    • (2009) Psychopharmacology (Berl) , vol.206 , pp. 23-37
    • Corrigall, W.A.1
  • 17
    • 78650770353 scopus 로고    scopus 로고
    • Tobacco dependence, the insular cortex and the hypocretin connection
    • P.J. Kenny Tobacco dependence, the insular cortex and the hypocretin connection Pharmacol Biochem Behav 97 2011 700 707
    • (2011) Pharmacol Biochem Behav , vol.97 , pp. 700-707
    • Kenny, P.J.1
  • 19
    • 77952777621 scopus 로고    scopus 로고
    • Nicotine self-administration in the rat: Effects of hypocretin antagonists and changes in hypocretin mRNA
    • M.G. LeSage, J.L. Perry, C.M. Kotz, D. Shelley, W.A. Corrigall Nicotine self-administration in the rat: Effects of hypocretin antagonists and changes in hypocretin mRNA Psychopharmacology (Berl) 209 2010 203 212
    • (2010) Psychopharmacology (Berl) , vol.209 , pp. 203-212
    • Lesage, M.G.1    Perry, J.L.2    Kotz, C.M.3    Shelley, D.4    Corrigall, W.A.5
  • 20
    • 76649130906 scopus 로고    scopus 로고
    • Hypocretins regulate the anxiogenic-like effects of nicotine and induce reinstatement of nicotine-seeking behavior
    • A. Plaza-Zabala, E. Martín-García, L. de Lecea, R. Maldonado, F. Berrendero Hypocretins regulate the anxiogenic-like effects of nicotine and induce reinstatement of nicotine-seeking behavior J Neurosci 30 2010 2300 2310
    • (2010) J Neurosci , vol.30 , pp. 2300-2310
    • Plaza-Zabala, A.1    Martín-García, E.2    De Lecea, L.3    Maldonado, R.4    Berrendero, F.5
  • 24
    • 45549097012 scopus 로고    scopus 로고
    • Measurement of immediate-early gene activation- c-fos and beyond
    • DOI 10.1111/j.1365-2826.2008.01734.x
    • K.J. Kovács Measurement of immediate-early gene activation c-fos and beyond J Neuroendocrinol 20 2008 665 672 (Pubitemid 351858715)
    • (2008) Journal of Neuroendocrinology , vol.20 , Issue.6 , pp. 665-672
    • Kovacs, K.J.1
  • 25
    • 77954033594 scopus 로고    scopus 로고
    • Activation of the hypothalamic-pituitary-adrenal axis by addictive drugs: Different pathways, common outcome
    • A. Armario Activation of the hypothalamic-pituitary-adrenal axis by addictive drugs: Different pathways, common outcome Trends Neurosci 31 2010 318 325
    • (2010) Trends Neurosci , vol.31 , pp. 318-325
    • Armario, A.1
  • 28
    • 0035925698 scopus 로고    scopus 로고
    • Gene expression and protein distribution of the orexin-1 receptor in the rat brain and spinal cord
    • DOI 10.1016/S0306-4522(01)00033-1, PII S0306452201000331
    • G.J. Hervieu, J.E. Cluderay, D.C. Harrison, J.C. Roberts, R.A. Leslie Gene expression and protein distribution of the orexin-1 receptor in the rat brain and spinal cord Neuroscience 103 2001 777 797 (Pubitemid 32239341)
    • (2001) Neuroscience , vol.103 , Issue.3 , pp. 777-797
    • Hervieu, G.J.1    Cluderay, J.E.2    Harrison, D.C.3    Roberts, J.C.4    Leslie, R.A.5
  • 29
    • 0036460171 scopus 로고    scopus 로고
    • Orexin receptor-1 (OX-R1) immunoreactivity in chemically identified neurons of the hypothalamus: Focus on orexin targets involved in control of food and water intake
    • DOI 10.1046/j.0953-816x.2001.01859.x
    • M. Bckberg, G. Hervieu, S. Wilson, B. Meister Orexin receptor-1 (OX-R1) immunoreactivity in chemically identified neurons of the hypothalamus: Focus on orexin targets involved in control of food and water intake Eur J Neurosci 15 2002 315 328 (Pubitemid 35471953)
    • (2002) European Journal of Neuroscience , vol.15 , Issue.2 , pp. 315-328
    • Backberg, M.1    Hervieu, G.2    Wilson, S.3    Meister, B.4
  • 30
    • 0024389216 scopus 로고
    • Severity of withdrawal symptoms as a predictor of outcome of an attempt to quit smoking
    • R.J. West, P. Hajek, M. Belcher Severity of withdrawal symptoms as a predictor of outcome of an attempt to quit smoking Psychol Med 19 1989 981 985 (Pubitemid 20012264)
    • (1989) Psychological Medicine , vol.19 , Issue.4 , pp. 981-985
    • West, R.J.1    Hajek, P.2    Belcher, M.3
  • 31
    • 58249130368 scopus 로고    scopus 로고
    • Attempts to quit smoking and relapse: Factors associated with success or failure from the ATTEMPT cohort study
    • X. Zhou, J. Nonnemaker, B. Sherrill, A.W. Gilsenan, F. Coste, R. West Attempts to quit smoking and relapse: Factors associated with success or failure from the ATTEMPT cohort study Addict Behav 34 2009 365 373
    • (2009) Addict Behav , vol.34 , pp. 365-373
    • Zhou, X.1    Nonnemaker, J.2    Sherrill, B.3    Gilsenan, A.W.4    Coste, F.5    West, R.6
  • 33
    • 68249087462 scopus 로고    scopus 로고
    • Orexin/hypocretin signaling at the orexin 1 receptor regulates cue-elicited cocaine-seeking
    • R.J. Smith, R.E. See, G. Aston-Jones Orexin/hypocretin signaling at the orexin 1 receptor regulates cue-elicited cocaine-seeking Eur J Neurosci 30 2009 493 503
    • (2009) Eur J Neurosci , vol.30 , pp. 493-503
    • Smith, R.J.1    See, R.E.2    Aston-Jones, G.3
  • 34
    • 79955034382 scopus 로고    scopus 로고
    • Selective blockade of the orexin-2 receptor attenuates ethanol self-administration, place preference, and reinstatement
    • J.R. Shoblock, N. Welty, L. Aluisio, I. Fraser, S.T. Motley, K. Morton Selective blockade of the orexin-2 receptor attenuates ethanol self-administration, place preference, and reinstatement Psychopharmacology (Berl) 215 2011 191 203
    • (2011) Psychopharmacology (Berl) , vol.215 , pp. 191-203
    • Shoblock, J.R.1    Welty, N.2    Aluisio, L.3    Fraser, I.4    Motley, S.T.5    Morton, K.6
  • 35
    • 46249085450 scopus 로고    scopus 로고
    • Orexin mediates the expression of precipitated morphine withdrawal and concurrent activation of the nucleus accumbens shell
    • R. Sharf, M. Sarhan, R.J. DiLeone Orexin mediates the expression of precipitated morphine withdrawal and concurrent activation of the nucleus accumbens shell Biol Psychiatry 64 2008 175 183
    • (2008) Biol Psychiatry , vol.64 , pp. 175-183
    • Sharf, R.1    Sarhan, M.2    Dileone, R.J.3
  • 37
    • 0033081871 scopus 로고    scopus 로고
    • Synaptic interaction between hypocretin (orexin) and neuropeptide Y cells in the rodent and primate hypothalamus: A novel circuit implicated in metabolic and endocrine regulations
    • T.L. Horvath, S. Diano, A.N. van den Pol Synaptic interaction between hypocretin (orexin) and neuropeptide Y cells in the rodent and primate hypothalamus: A novel circuit implicated in metabolic and endocrine regulations J Neurosci 19 1999 1072 1087 (Pubitemid 29066169)
    • (1999) Journal of Neuroscience , vol.19 , Issue.3 , pp. 1072-1087
    • Horvath, T.L.1    Diano, S.2    Van Den Pol, A.N.3
  • 38
    • 34247567169 scopus 로고    scopus 로고
    • Activation of stress-related hypothalamic neuropeptide gene expression during morphine withdrawal
    • DOI 10.1111/j.1471-4159.2006.04421.x
    • C. Nez, A. Földes, M.L. Laorden, M.V. Milanes, K.J. Kovács Activation of stress-related hypothalamic neuropeptide gene expression during morphine withdrawal J Neurochem 101 2007 1060 1071 (Pubitemid 46683869)
    • (2007) Journal of Neurochemistry , vol.101 , Issue.4 , pp. 1060-1071
    • Nunez, C.1    Foldes, A.2    Laorden, M.L.3    Milanes, M.V.4    Kovacs, K.J.5
  • 39
    • 3843117595 scopus 로고    scopus 로고
    • Regulation of affect by the lateral septum: Implications for neuropsychiatry
    • DOI 10.1016/j.brainresrev.2004.04.009, PII S0165017304000529
    • T.P. Sheehan, R.A. Chambers, D.S. Russell Regulation of affect by the lateral septum: Implications for neuropsychiatry Brain Res Brain Res Rev 46 2004 71 117 (Pubitemid 39036164)
    • (2004) Brain Research Reviews , vol.46 , Issue.1 , pp. 71-117
    • Sheehan, T.P.1    Chambers, R.A.2    Russell, D.S.3
  • 40
    • 79951509897 scopus 로고    scopus 로고
    • The modulatory role of the lateral septum on neuroendocrine and behavioral stress responses
    • G.M. Singewald, A. Rjabokon, N. Singewald, K. Ebner The modulatory role of the lateral septum on neuroendocrine and behavioral stress responses Neuropsychopharmacology 36 2011 793 804
    • (2011) Neuropsychopharmacology , vol.36 , pp. 793-804
    • Singewald, G.M.1    Rjabokon, A.2    Singewald, N.3    Ebner, K.4
  • 41
    • 0032701199 scopus 로고    scopus 로고
    • Stimulation of nicotinic receptors in the lateral septal nucleus increases anxiety
    • DOI 10.1046/j.1460-9568.1999.00823.x
    • A.M. Ouagazzal, P.J. Kenny, S.E. File Stimulation of nicotinic receptors in the lateral septal nucleus increases anxiety Eur J Neurosci 11 1999 3957 3962 (Pubitemid 29537575)
    • (1999) European Journal of Neuroscience , vol.11 , Issue.11 , pp. 3957-3962
    • Ouagazzal, A.-M.1    Kenny, P.J.2    File, S.E.3
  • 42
    • 0033623289 scopus 로고    scopus 로고
    • The role of 5-HT1A receptors in mediating the anxiogenic effects of nicotine following lateral septal administration
    • S. Cheeta, P.J. Kenny, S.E. File The role of 5-HT1A receptors in mediating the anxiogenic effects of nicotine following lateral septal administration Eur J Neurosci 12 2000 3797 3802
    • (2000) Eur J Neurosci , vol.12 , pp. 3797-3802
    • Cheeta, S.1    Kenny, P.J.2    File, S.E.3
  • 44
    • 0034667242 scopus 로고    scopus 로고
    • Stimulation of in vivo dopamine transmission in the bed nucleus of stria terminalis by reinforcing drugs
    • E. Carboni, A. Silvagni, M.T. Rolando, G. Di Chiara Stimulation of in vivo dopamine transmission in the bed nucleus of stria terminalis by reinforcing drugs J Neurosci 20 2000 RC102
    • (2000) J Neurosci , vol.20 , pp. 102
    • Carboni, E.1    Silvagni, A.2    Rolando, M.T.3    Di Chiara, G.4
  • 45
    • 33646130602 scopus 로고    scopus 로고
    • Blockade of nicotinic acetylcholine or dopamine D1-like receptors in the central nucleus of the amygdala or the bed nucleus of the stria terminalis does not precipitate nicotine withdrawal in nicotine-dependent rats
    • S. Jonkman, A. Markou Blockade of nicotinic acetylcholine or dopamine D1-like receptors in the central nucleus of the amygdala or the bed nucleus of the stria terminalis does not precipitate nicotine withdrawal in nicotine-dependent rats Neurosci Lett 400 2006 140 145
    • (2006) Neurosci Lett , vol.400 , pp. 140-145
    • Jonkman, S.1    Markou, A.2
  • 46
    • 67349123847 scopus 로고    scopus 로고
    • Corticotropin-releasing factor within the central nucleus of the amygdala and the nucleus accumbens shell mediates the negative affective state of nicotine withdrawal in rats
    • C.A. Marcinkiewcz, M.M. Prado, S.K. Isaac, A. Marshall, D. Rylkova, A.W. Bruijnzeel Corticotropin-releasing factor within the central nucleus of the amygdala and the nucleus accumbens shell mediates the negative affective state of nicotine withdrawal in rats Neuropsycopharmacology 34 2009 1743 1752
    • (2009) Neuropsycopharmacology , vol.34 , pp. 1743-1752
    • Marcinkiewcz, C.A.1    Prado, M.M.2    Isaac, S.K.3    Marshall, A.4    Rylkova, D.5    Bruijnzeel, A.W.6
  • 47
    • 46149120544 scopus 로고    scopus 로고
    • A Role for Brain Stress Systems in Addiction
    • DOI 10.1016/j.neuron.2008.06.012, PII S0896627308005308
    • G. Koob A role for brain stress systems in addiction Neuron 59 2008 11 34 (Pubitemid 351905857)
    • (2008) Neuron , vol.59 , Issue.1 , pp. 11-34
    • Koob, G.F.1
  • 48
    • 0036788272 scopus 로고    scopus 로고
    • Morphine withdrawal-induced c-fos expression in the hypothalamic paraventricular nucleus is dependent on the activation of catecholaminergic neurones
    • M.L. Laorden, C. Nez, P. Almela, M.V. Milanés Morphine withdrawal-induced c-fos expression in the hypothalamic paraventricular nucleus is dependent on the activation of catecholaminergic neurones J Neurochem 83 2002 132 140
    • (2002) J Neurochem , vol.83 , pp. 132-140
    • Laorden, M.L.1    Nez, C.2    Almela, P.3    Milanés, M.V.4
  • 50
    • 79251484353 scopus 로고    scopus 로고
    • CRF2 mediates the increased noradrenergic activity in the hypothalamic paraventricular nucleus and the negative state of morphine withdrawal in rats
    • J. Navarro-Zaragoza, C. Nez, J. Ruiz-Medina, M.L. Laorden, O. Valverde, M.V. Milanés CRF2 mediates the increased noradrenergic activity in the hypothalamic paraventricular nucleus and the negative state of morphine withdrawal in rats Br J Pharmacol 162 2011 851 862
    • (2011) Br J Pharmacol , vol.162 , pp. 851-862
    • Navarro-Zaragoza, J.1    Nez, C.2    Ruiz-Medina, J.3    Laorden, M.L.4    Valverde, O.5    Milanés, M.V.6
  • 52
    • 33846786970 scopus 로고    scopus 로고
    • 1 Receptor Stress System Exacerbates the Somatic Signs of Opiate Withdrawal
    • DOI 10.1016/j.neuron.2007.01.022, PII S0896627307000633
    • F. Papaleo, P. Kitchener, A. Contarino Disruption of the CFR/CRF1 receptor stress system exacerbates the somatic signs of opiate withdrawal Neuron 53 2007 577 589 (Pubitemid 46216753)
    • (2007) Neuron , vol.53 , Issue.4 , pp. 577-589
    • Papaleo, F.1    Kitchener, P.2    Contarino, A.3
  • 53
    • 77951055922 scopus 로고    scopus 로고
    • Effects of corticotropin-releasing factor receptor-1 antagonists on the brain stress system responses to morphine withdrawal
    • J. Navarro-Zaragoza, C. Nez, M.L. Laorden, M.V. Milanés Effects of corticotropin-releasing factor receptor-1 antagonists on the brain stress system responses to morphine withdrawal Mol Pharmacol 77 2010 864 873
    • (2010) Mol Pharmacol , vol.77 , pp. 864-873
    • Navarro-Zaragoza, J.1    Nez, C.2    Laorden, M.L.3    Milanés, M.V.4
  • 54
    • 29744457095 scopus 로고    scopus 로고
    • The corticotrophin-releasing factor/hypocretin circuitry
    • R. Winsky-Sommerer, B. Boutrel, L. de Lecea The corticotrophin-releasing factor/hypocretin circuitry Mol Neurobiol 32 2005 285 294
    • (2005) Mol Neurobiol , vol.32 , pp. 285-294
    • Winsky-Sommerer, R.1    Boutrel, B.2    De Lecea, L.3
  • 56
    • 0037086828 scopus 로고    scopus 로고
    • Orexin actions in hypothalamic paraventricular nucleus: Physiological consequences and cellular correlates
    • DOI 10.1016/S0167-0115(01)00353-6, PII S0167011501003536
    • W.K. Samson, M.M. Taylor, M. Follwell, A.V. Ferguson Orexin actions in hypothalamic paraventricular nucleus: Physiological consequences and cellular correlates Regul Pept 104 2002 97 103 (Pubitemid 34119379)
    • (2002) Regulatory Peptides , vol.104 , Issue.1-3 , pp. 97-103
    • Samson, W.K.1    Taylor, M.M.2    Follwell, M.3    Ferguson, A.V.4
  • 57
    • 0037115276 scopus 로고    scopus 로고
    • Cellular mechanisms of orexin actions on paraventricular nucleus neurones in rat hypothalamus
    • DOI 10.1113/jphysiol.2002.030049
    • M.J. Follwell, A.V. Ferguson Cellular mechanisms of orexin actions on paraventricular nucleus neurones in rat hypothalamus J Physiol 545 2002 855 867 (Pubitemid 36024425)
    • (2002) Journal of Physiology , vol.545 , Issue.3 , pp. 855-867
    • Follwell, M.J.1    Ferguson, A.V.2
  • 58
    • 67651111836 scopus 로고    scopus 로고
    • Characterization of the projections to the hypothalamic paraventricular and periventricular nuclei in the female sheep brain, using retrograde tracing and immunohistochemistry
    • Y. Qi, M.R. Namavar, J. Iqbal, B.J. Oldfield, I.J. Clarke Characterization of the projections to the hypothalamic paraventricular and periventricular nuclei in the female sheep brain, using retrograde tracing and immunohistochemistry Neuroendocrinology 90 2009 31 53
    • (2009) Neuroendocrinology , vol.90 , pp. 31-53
    • Qi, Y.1    Namavar, M.R.2    Iqbal, J.3    Oldfield, B.J.4    Clarke, I.J.5
  • 59
    • 0030822801 scopus 로고    scopus 로고
    • Physiological evidence for local excitatory synaptic circuits in the rat hypothalamus
    • C. Boudaba, L.A. Schrader, J.G. Tasker Physiological evidence for local excitatory synaptic circuits in the rat hypothalamus J Neurophysiol 77 1997 3396 3400 (Pubitemid 27290904)
    • (1997) Journal of Neurophysiology , vol.77 , Issue.6 , pp. 3396-3400
    • Boudaba, C.1    Schrader, L.A.2    Tasker, J.G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.