Role of MgADP in the development of diastolic dysfunction in the intact beating rat heart

Journal of Clinical Investigation

Volumn 99, Issue 4, 1997, Pages 745-751

  Tian, Rong ^a   Christe, Michael E ^a   Spindler, Matthias ^a   Hopkins, James C A ^a   Halow, Jessica M ^b   Camacho, S Albert ^c   Ingwall, Joanne S ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

ATP; calcium; cross bridge cycling; inorganic phosphate; relaxation

Indexed keywords

ADENOSINE DIPHOSPHATE; CALCIUM ION; MAGNESIUM ION;

ACTIN MYOSIN INTERACTION; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIASTOLE; GLYCOLYSIS; HEART LEFT VENTRICLE ENDDIASTOLIC PRESSURE; HEART LEFT VENTRICLE RELAXATION; HEART MUSCLE CONTRACTILITY; MALE; NONHUMAN; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; RAT; SARCOMERE;

EID: 0031035444     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI119220     Document Type: Article

References (35)

1. Taylor, E.W. 1979. Mechanism of actomyosin ATPase and the problem of muscle contraction. CRC Crit. Rev. Biochem. 7:103-164.
2. Eisenberg, E., and L.E. Greene. 1980. The relation between muscle physiology and muscle biochemistry. Annu. Rev. Physiol. 42:293-309.
3. Rayment, I., H.M. Holden, M. Whittaker, C.B. Yohn, M. Lorenz, K.C. Holmes, and R.A. Milligan. 1993. Structure of the actin-myosin complex and its implications for muscle contraction. Science (Wash. D.C.). 261:58-65.
4. Hibberd, M.G., and D.R. Trentham. 1986. Relationship between chemical and mechanical events during muscular contraction. Annu. Rev. Biophys. Chem. 15:119-161.
5. Dantzig, J.A., Y.E. Goldman, N.C. Millar, J. Laktis, and E. Homsher. 1992. Reversal of the cross-bridge force-generating transition by photogeneration of phosphate in rabbit psoas muscle fibers. J. Physiol (Lond.). 451:247-278.
6. Cooke, R., and E. Pate. 1985. The effects of ADP and phosphate on the contraction of muscle fibers. Biophys. J. 48:789-798.
7. Hamman, B.L., J.A. Bittl, W.E. Jacobus, P.D. Allen, R.S. Spencer, R. Tian, and J.S. Ingwall. 1995. Inhibition of creatine kinase reaction decreases the contractile reserve of isolated rat hearts. Am. J. Physiol. 269:H1030-H1036.
8. Tian, R., and J.S. Ingwall. 1996. Energetic basis for reduced contractile reserve in isolated rat hearts. Am. J. Physiol. 270:H1207-H1216.
9. Kagaya Y., E.O. Weinberg, N. Ito, T. Mochizuki, W.H. Barry, and B.H. Lorell. 1995. Glycolytic inhibition: effects on diastolic relaxation and intracellular calcium handling in hypertrophied rat ventricular myocytes. J. Clin. Invest. 95:2766-2776.
10. Polimeni, P.I., and S.I. Buraczewski. 1988. Expansion of extracellular tracer spaces in the isolated heart perfused with crystalloid solution: expansion of extracellular space, transsarcolemmal leakage, or both? J. Mol. Cell. Cardiol. 20:15-22.
11. eq of the creatine kinase reaction and other phosphate hydrolyses and phosphate transfer reactions. J. Biol. Chem. 254(14):6528-6537.
12. Tian, R., P. Gaudron, S. Neubauer, K. Hu, and G. Ertl. 1995. Alterations of performance and oxygen utilization in chronically infarcted rat hearts. J. Mol. Cell. Cardiol. 28:321-330.
13. Lowry, O.H., M.J. Rosebrough, A.L. Farr, and R.J. Randall. 1951. Protein measurement with the Phenol Folin reagent. J. Biol. Chem. 193:265-275.
14. Rosalki, S.P. 1967. An improved procedure for serum creatine phosphokinase determination. J. Lab. Clin. Med. 69:696-705.
15. Oblinger, M.M., L.G. Foe, D. Kwiatkoska, and R.G. Kemp. 1988. Phosphofructokinase in the rat nervous system: regional differences in activity and characteristics of axonal transport. J. Neurosci. Res. 21:25-34.
16. Bergmeyer, H.U. 1974. In Methods of Enzymatic Analysis. H.U. Bergmeyer and K. Gawehn, editors. Academic Press Inc., Orlando, FL. vol. 1:466-467.
17. Bernstein L.H., and J. Everse. 1975. Determination of the isoenzyme levels of lactate dehydrogenase. Methods Enzymol. 41:47-49.
18. 2+] in whole perfused rat hearts using indo-1 fluorometry. Biophys. J. 65:1973-1982.
19. 2+] in perfused hearts. Biophys. J. 65:1983-1993.
20. Figueredo, V.M., R. Brandes, M.W. Weiner, B.M. Massie, and S.A. Camacho. 1993. Endocardial versus epicardial differences of intracellular free calcium under normal and ischemic conditions in perfused rat hearts. Circ. Res. 72: 1082-1090.
21. 2+. Biophys. J. 70:2571-2580.
22. 2+ transient decline is an early manifestation of pressure overload hypertrophy in rat hearts. Am. J. Physiol. 271:H228-234.
23. Saddik, M., and G.D. Lopaschuk. 1991. Myocardial triglyceride turnover and contribution to energy substrate utilization in isolated working rat hearts. J. Biol. Chem. 266:8162-8170.
24. Cunningham, M.J., C.S. Apstein, E.O. Weinberg, W.M. Vogel, and B.H. Lorell. 1990. Influence of glucose and insulin on the exaggerated diastolic and systolic dysfunction of hypertrophied rat hearts during hypoxia. Circ. Res. 66: 406-415.
25. Bernard, M., S. Neubauer, and J.S. Ingwall. 1994. On the relations among ATP hydrolysis, cation accumulation and diastolic dysfunction. In Diastolic Relaxation of the Heart. B.H. Lorell, and W. Grossman, editors. Kluwer Academic Publishers, Norwell, MA. 73-78.
26. Siemankowski, R.F., M.O. Wiseman, and H.D. White. 1985. ADP dissociation from actomvosin subfragment 1 is sufficiently slow to limit the unloaded shortening velocity in vertebrate skeletal muscle. Proc. Natl. Acad. Sci. USA. 82:658-662.
27. Danztig, J.A., M.G. Hibberd, D.R. Trentham, and Y.E. Goldman. 1991. Cross-bridge kinetics in the presence of MgADP investigated by photolysis of caged ATP in rabbit psoas muscle fibers. J. Physiol. 432:639-680.
28. Ma, Y.Z., and E.W. Taylor. 1994. Kinetics mechanism of myofibril ATPase. Biophys. J. 66:1542-2553.
29. Chase P.B, and M.J. Kushmerick. 1995. Effect of physiological ADP concentration on contraction of single skinned fibers from rabbit fast and slow muscles. Am. J. Physiol. 268:C480-C489.
30. Yamashita H., M. Sata, S. Sugiura, S. Momomura, T. Serizawa, and M. Iizuka. 1994. ADP inhibits the sliding velocity of fluorescent actin filaments on cardiac and skeletal myosins. Circ. Res. 74:1027-1033.
31. Whittaker M., E.M. Wilson-Kubalek, J.E. Smith, L. Faust, R.A. Milligan, and H.L. Sweeney. 1995. A 35-A movement of smooth muscle myosin on ADP release. Nature (Lond.). 378:748-751.
32. Tian, R., L. Nascimben, E.O. Weinberg, J.S. Ingwall, and B.H. Lorell. 1995. Altered regulation of [ADP] in cardiac hypertrophy severely impairs diastolic function. Circulation. 92(suppl. 1):I-658 (Abstr.)
33. 2+ uptake, content and release. In Excitation-Contraction Coupling and Cardiac Contractile Force. Kluwer Academic Publishers Group, Dordrecht, The Netherlands. 93-118.
34. Kammermeier, H. 1987. High energy phosphate of the myocardium: concentration versus free energy change. Basic Res. Cardiol. 82:31-36.
35. Owen, P., S. Dennis, and L.H. Opie. 1990. Glucose flux rate regulates onset of ischemic contracture in globally underperfused rat hearts. Circ. Res. 66: 344-354.