Serum protein levels of brain-derived neurotrophic factor and tropomyosin-related kinase B in bipolar disorder: Effects of mood stabilizers

Neuropsychobiology

Volumn 65, Issue 2, 2012, Pages 65-69

  Huang, Tiao Lai ^a,c   Hung, Yi Yung ^a   Lee, Chien Te ^b   Chen, Rong Fu ^c  

^a Department of Psychiatry ^*  (Taiwan)

^b Division of Nephrology   (Taiwan)

^c CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

Author keywords

Bipolar disorder; Brain derived neurotrophic factor; Tropomyosin related kinase B

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; CHLORPROMAZINE; CLOZAPINE; HALOPERIDOL; LITHIUM; LORAZEPAM; OLANZAPINE; QUETIAPINE; RISPERIDONE; VALPROIC ACID; ZOLPIDEM;

ADULT; ARTICLE; BIPOLAR I DISORDER; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG EFFECT; FEMALE; HUMAN; MALE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL;

ADULT; ANALYSIS OF VARIANCE; ANTIMANIC AGENTS; BIPOLAR DISORDER; BRAIN-DERIVED NEUROTROPHIC FACTOR; FEMALE; HUMANS; LITHIUM CHLORIDE; MALE; MIDDLE AGED; PROTEIN KINASES; RETROSPECTIVE STUDIES; VALPROIC ACID; YOUNG ADULT;

EID: 84855396303     PISSN: 0302282X     EISSN: 14230224     Source Type: Journal    
DOI: 10.1159/000328991     Document Type: Article

References (43)

1. Thoenen H: Neurotrophins and neuronal plasticity. Science 1995; 270: 593-598.
2. Valent A, Danglot G, Bernheim A: Mapping of the tyrosine kinase receptors trkA (NTRK1), trkB (NTRK2) and trkC(NTRK3) to human chromosomes 1q22, 9q22 and 15q25 by fluorescence in situ hybridization. Eur J Hum Genet 1997; 5: 102-104. (Pubitemid 27249967)
3. Schinder AF, Poo M: The neurotrophin hypothesis for synaptic plasticity. Trends Neurosci 2000; 23: 639-645. (Pubitemid 32007891)
4. Pencea V, Bingaman KD, Wiegand SJ, Luskin MB: Infusion of brain-derived neurotrophic factor into the lateral ventricle of the adult rat leads to new neurons in the parenchyma of the striatum, septum, thalamus, and hypothalamus. J Neurosci 2001; 21: 6706-6717. (Pubitemid 32781115)
5. Karege F, Perret G, Bondolfi G, Schwald M, Bertschy G, Aubry JM: Decreased serum brain-derived neurotrophic factor levels in major depressed patients. Psychiatry Res 2002; 109: 143-148. (Pubitemid 34258493)
6. Tsai SJ: Down-regulation of the Trk-B signal pathway: the possible pathogenesis of major depression. Med Hypotheses 2004; 62: 215-218.
7. Gonul AS, Akdeniz F, Taneli F, Donat O, Eker C, Vahip S: Effects of treatment on serum brain-derived neurotrophic factor levels in depressed patients. Eur Arch Psychiatry Clin Neurosci 2005; 255: 381-386. (Pubitemid 43029827)
8. Cunha AB, Frey BN, Andreazza AC, Goi JD, Rosa AR, Goncalves CA, Santin A, Kapczinski F: Serum brain-derived neurotrophic factor is decreased in bipolar disorder during depressive and manic episodes. Neurosci Lett 2006; 398: 215-219. (Pubitemid 43673698)
9. Brunoni AR, Lopes M, Fregni F: A systematic review and meta-analysis of clinical studies on major depression and BDNF levels: implications for the role of neuroplasticity in depression. Int J Neuropsychopharmacol 2008; 11: 1169-1180.
10. Huang TL, Lee CT, Liu YL: Serum brain-derived neurotrophic factor levels in patients with major depression: effects of antidepressants. J Psychiatric Res 2008; 42: 521-525.
11. Karege F, Schwald M, El Kouaissi R: Druginduced decrease of protein kinase a activity reveals alteration in BDNF expression of bipolar affective disorder. Neuropsychopharmacology 2004; 29: 805-812. (Pubitemid 38402489)
12. Karege F, Schwald M, Papadimitriou P, Lachausse C, Cisse M: The cAMP-dependent protein kinase A and brain-derived neurotrophic factor expression in lymphoblast cells of bipolar affective disorder. J Affect Disord 2004; 79: 187-192. (Pubitemid 38340542)
13. Frey BN, Andreazz AC, Cereser KM, Martins MR, Valvassori SS, Reus GZ, Quevedo J, Kapczinski F: Effects of mood stabilizers on hippocampus BDNF levels in an animal model of mania. Life Sci 2006; 79: 281-286. (Pubitemid 43782552)
14. Okada T, Hashimoto R, Numakawa T, Lijima Y, Kosuga A, Tatsumi M, Kamijima K, Kato T, Kunugi H: A complex polymorphic region in the brain-derived neurotrophic factor gene confers susceptibility to bipolar disorder and affects transcriptional activity. Mol Psychiatry 2006; 11: 695-703. (Pubitemid 43989816)
15. Tsai SJ: TrkB partial agonists: potential treatment strategy for epilepsy, mania, and autism. Med Hypotheses 2006; 66: 173-175.
16. Post RM: Role of BDNF in bipolar and unipolar disorder: clinical and theoretical implications. J Psychiatric Res 2007; 41: 979-990. (Pubitemid 47301944)
17. Kapczinski F, Frey BN, Kauer-Sant'Anna M, Grassi-Oliveira R: Brain-derived neurotrophic factor and neuroplasticity in bipolar disorder. Expert Rev Neurother 2008; 8: 1101-1113. (Pubitemid 351962077)
18. Lin PY: State-dependent decrease in levels of brain-derived neurotrophic factor in bipolar disorder: a meta-analytic study. Neurosci Lett 2009; 466: 139-143.
19. Tramontina JF, Andreazza AC, Kauer-Sant'anna M, Stertz L, Goi J, Chiarani F, Bock H, Saraiva-Pereira ML, Kapczinski F: Brain-derived neurotrophic factor serum levels before and after treatment for acute mania. Neurosci Lett 2009; 452: 111-113.
20. Fernandes BS, Gama CS, Kauer-Sant'Anna M, Lobato MI, Belmonte-de-Abreu P, Kapczinski F: Serum brain-derived neurotrophic factor in bipolar and unipolar depression: a potential adjunctive tool for differential diagnosis. J Psychiatric Res 2009; 43: 1200-1204.
21. Palomino A, Vallejo-Illarramendi A, González-Pinto A, Aldama A, González-Gómez C, Mosquera F, González-García G, Matute C: Decreased levels of plasma BDNF in first-episode schizophrenia and bipolar disorder patients. Schizophr Res 2006; 86: 321-322. (Pubitemid 44234056)
22. Yoshimura R, Nakano Y, Hori H, Ikenouchi A, Ueda N, Nakamura J: Effect of risperidone on plasma catecholamine metabolites and brain-derived neurotrophic factor in patients with bipolar disorders. Hum Psychopharmacol 2006; 21: 433-438. (Pubitemid 44660182)
23. Machado-Vieira R, Dietrich MO, Leke R, Cereser VH, Zanatto V, Kapczinski F, Souza DO, Portela LV, Gentil V: Decreased plasma brain derived neurotrophic factor levels in unmedicated bipolar patients during manic episode. Biol Psychiatry 2007; 61: 142-144. (Pubitemid 46072782)
24. Dias VV, Brissos S, Frey BN, Andreazza AC, Cardoso C, Kapczinski F: Cognitive function and serum levels of brain-derived neurotrophic factor in patients with bipolar disorder. Bipolar Disord 2009; 11: 663-671.
25. Kauer-Sant'Anna M, Kapczinski F, Andreazza AC, Bond DJ, Lam RW, Young LT: Brainderived neurotrophic factor and inflammatory markers in patients with early-vs. late-stage bipolar disorder. Int J Neuropsychopharmacol 2009; 12: 447-458.
26. Monteleone P, Serritella C, Martiadis V, Maj M: Decreased levels of serum brain-derived neurotrophic factor in both depressed and euthymic patients with unipolar depression and in euthymic patients with bipolar I and II disorders. Bipolar Disord 2008; 10: 95-100.
27. Dwivedi Y, Rizavi HS, Conley RR, Roberts RC, Tamminga CA, Pandey GN: Altered gene expression of brain-derived neurotrophic factor and receptor tyrosine kinase B in postmortem brain of suicide subjects. Arch Gen Psychiatry 2003; 60: 804-815. (Pubitemid 36960912)
28. Dwivedi Y, Rizavi HS, Zhang H, Mondal AC, Roberts RC, Conley RR, Pandey GN: Neurotrophin receptor activation and expression in human postmortem brain: effect of suicide. Biol Psychiatry 2009; 65: 319-328.
29. Hung YY, Lin CJ, Huang TL: Higher serum tropomyosin-related kinase B protein level in major depression. Prog Neuropsychopharmacol Biol Psychiatry 2010; 34: 610-612.
30. First MB, Spitzer RL, Gibbon M, Williams JBW: User's Guide for the Structured Clinical Interview for DSM-IV Axis I Disorders-Clinician Version (SCID-CV). Washington, American Psychiatric Press, 1997.
31. Young RC, Biggs JT, Ziegler VE, Meyer DA: A rating scale for mania: reliability, validity and sensitivity. Br J Psychiatry 1978; 153: 429-435. (Pubitemid 9006756)
32. Chong MY, Wilkinson G: Validation of 30-and 12-item versions of the Chinese Health Questionnaire (CHQ) in patients admitted for general health screening. Psychol Med 1989; 19: 495-505. (Pubitemid 19176147)
33. Elfving B, Plougmann PH, Wegener G: Detection of brain-derived neurotrophic factor (BDNF) in rat blood and brain preparations using ELISA: pitfalls and solutions. J Neurosci Methods 2010; 187: 73-77.
34. Pan W, Banks WA, Fasold MB, Bluth J, Kastin AJ: Transport of brain-derived neurotrophic factor across the blood-brain barrier. Neuropharmacology 1998; 37: 1553-1561. (Pubitemid 28550429)
35. Karege F, Schwald M, Cisse M: Postnatal developmental profile of brain-derived neurotrophic factor in rat brain and platelets. Neurosci Lett 2002; 328: 261-264. (Pubitemid 34876661)
36. Elfving B, Plougmann PH, Müller HK, Mathé AA, Rosenberg R, Wegener G: Inverse correlation of brain and blood BDNF levels in a genetic rat model of depression. Int J Neuropsychopharmacol 2010; 13: 563-572.
37. Tsai SJ: Possible involvement of the BDNFdependent pathway in treatment-emergent suicidality or decreased response to antidepressants. Med Hypotheses 2005; 35: 942-946.
38. Jornada LK, Moretti M, Valvassori SS, Ferreira CL, Padilha PT, Arent CO, Fries GR, Kapczinski F, Quevedo J: Effects of mood stabilizers on hippocampus and amygdala BDNF levels in an animal model of mania induced by ouabain. J Psychiatric Res 2010; 44: 506-510.
39. Solum DT, Handa RJ: Estrogen regulates the development of brain derived neurotrophic factor mRNA and protein in the rat hippocampus. J Neurosci 2002; 22: 2650-2659. (Pubitemid 37465814)
40. Cavus I, Duman RS: Influence of estradiol, stress, and 5-HT 2A agonist treatment on brain-derived neurotrophic factor expression in female rats. Biol Psychiatry 2003; 54: 59-69. (Pubitemid 36776724)
41. Ren-Patterson RF, Cochran LW, Holmes A, Lesch KP, Lu B, Murphy DL: Gender-dependent modulation of brain monoamines and anxiety-like behaviors in mice with genetic serotonin transporter and BDNF deficiencies. Cell Mol Neurobiol 2006; 26: 755-780.
42. Haniu M, Montestruque S, Bures EJ, Talvenheimo J, Toso R, Lewis-Sandy S, Welcher AA, Rohde MF: Interactions between brainderived neurotrophic factor and the TRKB receptor: identification of two ligand binding domains in soluble TRKB by affinity separation and chemical cross-linking. J Biol Chem 1997; 272: 25296-25303. (Pubitemid 27415720)
43. Luberg K, Wong J, Weickert CS, Timmusk T: Human TrkB gene: novel alternative transcripts, protein isoforms and expression pattern in the prefrontal cerebral cortex during postnatal development. J Neurochem 2010; 113: 952-964.