A complex polymorphic region in the brain-derived neurotrophic factor (BDNF) gene confers susceptibility to bipolar disorder and affects transcriptional activity

Molecular Psychiatry

Volumn 11, Issue 7, 2006, Pages 695-703

  Okada, T ^a   Hashimoto, R ^a   Numakawa, T ^a   Iijima, Y ^a   Kosuga, A ^b   Tatsumi, M ^b,c   Kamijima, K ^b   Kato, T ^d   Kunugi, H ^a  

^a NATIONAL INSTITUTE OF NEUROSCIENCE   (Japan)

^b SHOWA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c Yokohama Shinryo Clinic   (Japan)

^d RIKEN BRAIN SCIENCE INSTITUTE   (Japan)

Author keywords

Association study; Bipolar disorder; Brain derived neurotrophic factor (BDNF); Polymorphism; Susceptibility; Transcriptional activity

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; DINUCLEOTIDE; DNA; LUCIFERASE; NUCLEOTIDE;

ADULT; ALLELE; ANIMAL CELL; ARTICLE; BIPOLAR DISORDER; CONTROLLED STUDY; DINUCLEOTIDE REPEAT; DISEASE ASSOCIATION; DISEASE PREDISPOSITION; DNA SEQUENCE; FEMALE; GENE; GENE LINKAGE DISEQUILIBRIUM; GENE SEQUENCE; GENETIC TRANSCRIPTION; HUMAN; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RAT; TRANSLATION INITIATION;

ADULT; ALLELES; AMINO ACID SUBSTITUTION; ANIMALS; BASE SEQUENCE; BIPOLAR DISORDER; BRAIN-DERIVED NEUROTROPHIC FACTOR; CASE-CONTROL STUDIES; CELLS, CULTURED; DINUCLEOTIDE REPEATS; FEMALE; GENE FREQUENCY; GENES, REPORTER; GENETIC PREDISPOSITION TO DISEASE; HUMANS; JAPAN; LINKAGE DISEQUILIBRIUM; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; MUTATION, MISSENSE; NEURONS; POINT MUTATION; POLYMORPHISM, GENETIC; RATS; RECOMBINANT FUSION PROTEINS; TRANSCRIPTION, GENETIC;

EID: 33745622389     PISSN: 13594184     EISSN: 14765578     Source Type: Journal    
DOI: 10.1038/sj.mp.4001822     Document Type: Article

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