Cardiac-oxidized antigens are targets of immune recognition by antibodies and potential molecular determinants in chagas disease pathogenesis

PLoS ONE

Volumn 7, Issue 1, 2012, Pages

  Dhiman, Monisha ^a   Zago, Maria Paola ^b   Nunez, Sonia ^c   Amoroso, Alejandro ^d   Rementeria, Hugo ^d   Dousset, Pierre ^d   Burgos, Federico Nunez ^c   Garg, Nisha Jain ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

^b UNIVERSIDAD NACIONAL DE SALTA   (Argentina)

^c Hospital Público de Gestión Descentralizada San Bernardo HPGDSA   (Argentina)

^d Hospital San Bernardo ^*  (Argentina)

Author keywords

[No Author keywords available]

Indexed keywords

3 NITROTYROSINE; 4 HYDROXYNONENAL; ANTIBODY; CARBONYL DERIVATIVE; CONNECTIN; HEART ANTIGEN; HYDROGEN PEROXIDE; MALONALDEHYDE; N TERT BUTYL ALPHA PHENYLNITRONE; REACTIVE OXYGEN METABOLITE; ANTIGEN; AUTOANTIBODY;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN RECOGNITION; ARTICLE; CHAGAS DISEASE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; HEART MUSCLE BIOPSY; HEART MUSCLE CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNE RESPONSE; IMMUNOGENICITY; IN VITRO STUDY; LD 50; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATION; PATHOGENESIS; PROTEIN TARGETING; RAT; TWO DIMENSIONAL GEL ELECTROPHORESIS; WESTERN BLOTTING; ANIMAL; ANTIBODY AFFINITY; C3H MOUSE; CLINICAL TRIAL (TOPIC); HEART; HEART MUSCLE; IMMUNOLOGY; METABOLISM; OXIDATION REDUCTION REACTION; PARASITOLOGY; PATHOLOGY; PROTEIN BINDING; SPRAGUE DAWLEY RAT; TRYPANOSOMA CRUZI;

MUS; RATTUS; RODENTIA; TRYPANOSOMA CRUZI;

ANIMALS; ANTIBODY AFFINITY; ANTIGENS; AUTOANTIBODIES; CHAGAS CARDIOMYOPATHY; CHAGAS DISEASE; CLINICAL TRIALS AS TOPIC; HEART; HUMANS; MICE; MICE, INBRED C3H; MYOCARDIUM; MYOCYTES, CARDIAC; OXIDATION-REDUCTION; PROTEIN BINDING; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; TRYPANOSOMA CRUZI;

EID: 84855391247     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0028449     Document Type: Article

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