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Volumn 18, Issue 1 SUPPL., 2012, Pages

Emerging Therapies in Hematopoietic Stem Cell Transplantation

Author keywords

Allogeneic; Azacytidine; Bortezomib; HDAC; Hypomethylating agent; Proteasome; Review

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; AZACITIDINE; BORTEZOMIB; CYCLOSPORIN; FLUDARABINE; GIVINOSTAT; METHOTREXATE; TACROLIMUS; THALIDOMIDE; THYMOCYTE ANTIBODY; VORINOSTAT;

EID: 84855370552     PISSN: 10838791     EISSN: 15236536     Source Type: Journal    
DOI: 10.1016/j.bbmt.2011.10.022     Document Type: Article
Times cited : (7)

References (59)
  • 1
    • 79953109315 scopus 로고    scopus 로고
    • Comparative analysis of risk factors for acute graft-versus-host disease and for chronic graft-versus-host disease according to National Institutes of Health consensus criteria
    • Flowers M.E., Inamoto Y., Carpenter P.A., et al. Comparative analysis of risk factors for acute graft-versus-host disease and for chronic graft-versus-host disease according to National Institutes of Health consensus criteria. Blood 2011, 117:3214-3219.
    • (2011) Blood , vol.117 , pp. 3214-3219
    • Flowers, M.E.1    Inamoto, Y.2    Carpenter, P.A.3
  • 2
    • 0035760863 scopus 로고    scopus 로고
    • The history and future of T-cell depletion as graft-versus-host disease prophylaxis for allogeneic hematopoietic stem cell transplantation
    • Ho V.T., Soiffer R.J. The history and future of T-cell depletion as graft-versus-host disease prophylaxis for allogeneic hematopoietic stem cell transplantation. Blood 2001, 98:3192-3204.
    • (2001) Blood , vol.98 , pp. 3192-3204
    • Ho, V.T.1    Soiffer, R.J.2
  • 3
    • 79959496711 scopus 로고    scopus 로고
    • Impact of immune modulation with anti-T-cell antibodies on the outcome of reduced-intensity allogeneic hematopoietic stem cell transplantation for hematologic malignancies
    • Soiffer R.J., Lerademacher J., Ho V., et al. Impact of immune modulation with anti-T-cell antibodies on the outcome of reduced-intensity allogeneic hematopoietic stem cell transplantation for hematologic malignancies. Blood 2011, 117:6963-6970.
    • (2011) Blood , vol.117 , pp. 6963-6970
    • Soiffer, R.J.1    Lerademacher, J.2    Ho, V.3
  • 4
    • 33646042263 scopus 로고    scopus 로고
    • HLA-C mismatch is associated with inferior survival after unrelated donor non-myeloablative hematopoietic stem cell transplantation
    • Ho V.T., Kim H.T., Liney D., et al. HLA-C mismatch is associated with inferior survival after unrelated donor non-myeloablative hematopoietic stem cell transplantation. Bone Marrow Transplant 2006, 37:845-850.
    • (2006) Bone Marrow Transplant , vol.37 , pp. 845-850
    • Ho, V.T.1    Kim, H.T.2    Liney, D.3
  • 5
    • 0035300479 scopus 로고    scopus 로고
    • The proteasome inhibitor PS-341 inhibits growth, induces apoptosis, and overcomes drug resistance in human multiple myeloma cells
    • Hideshima T., Richardson P., Chauhan D., et al. The proteasome inhibitor PS-341 inhibits growth, induces apoptosis, and overcomes drug resistance in human multiple myeloma cells. Cancer Res 2001, 61:3071-3076.
    • (2001) Cancer Res , vol.61 , pp. 3071-3076
    • Hideshima, T.1    Richardson, P.2    Chauhan, D.3
  • 6
    • 0031897632 scopus 로고    scopus 로고
    • NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses
    • Ghosh S., May M.J., Kopp E.B. NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses. Annu Rev Immunol 1998, 16:225-260.
    • (1998) Annu Rev Immunol , vol.16 , pp. 225-260
    • Ghosh, S.1    May, M.J.2    Kopp, E.B.3
  • 7
    • 0031985626 scopus 로고    scopus 로고
    • Role of proteasomes in T cell activation and proliferation
    • Wang X., Luo H., Chen H., Duguid W., Wu J. Role of proteasomes in T cell activation and proliferation. J Immunol 1998, 160:788-801.
    • (1998) J Immunol , vol.160 , pp. 788-801
    • Wang, X.1    Luo, H.2    Chen, H.3    Duguid, W.4    Wu, J.5
  • 8
    • 0034902354 scopus 로고    scopus 로고
    • Novel proteasome inhibitor PS-341 inhibits activation of nuclear factor-kappa B, cell survival, tumor growth, and angiogenesis in squamous cell carcinoma
    • Sunwoo J.B., Chen Z., Dong G., et al. Novel proteasome inhibitor PS-341 inhibits activation of nuclear factor-kappa B, cell survival, tumor growth, and angiogenesis in squamous cell carcinoma. Clin Cancer Res 2001, 7:1419-1428.
    • (2001) Clin Cancer Res , vol.7 , pp. 1419-1428
    • Sunwoo, J.B.1    Chen, Z.2    Dong, G.3
  • 9
    • 0035889230 scopus 로고    scopus 로고
    • Inhibition of NF-kappaB-dependent T cell activation abrogates acute allograft rejection
    • Finn P.W., Stone J.R., Boothby M.R., Perkins D.L. Inhibition of NF-kappaB-dependent T cell activation abrogates acute allograft rejection. J Immunol 2001, 167:5994-6001.
    • (2001) J Immunol , vol.167 , pp. 5994-6001
    • Finn, P.W.1    Stone, J.R.2    Boothby, M.R.3    Perkins, D.L.4
  • 10
    • 33745932074 scopus 로고    scopus 로고
    • Proteasome inhibitor bortezomib modulates TLR4-induced dendritic cell activation
    • Nencioni A., Schwarzenberg K., Brauer K.M., et al. Proteasome inhibitor bortezomib modulates TLR4-induced dendritic cell activation. Blood 2006, 108:551-558.
    • (2006) Blood , vol.108 , pp. 551-558
    • Nencioni, A.1    Schwarzenberg, K.2    Brauer, K.M.3
  • 11
    • 78751522626 scopus 로고    scopus 로고
    • Bortezomib suppresses function and survival of plasmacytoid dendritic cells by targeting intracellular trafficking of Toll-like receptors and endoplasmic reticulum homeostasis
    • Hirai M., Kadowaki N., Kitawaki T., et al. Bortezomib suppresses function and survival of plasmacytoid dendritic cells by targeting intracellular trafficking of Toll-like receptors and endoplasmic reticulum homeostasis. Blood 2011, 117:500-509.
    • (2011) Blood , vol.117 , pp. 500-509
    • Hirai, M.1    Kadowaki, N.2    Kitawaki, T.3
  • 12
    • 33646421393 scopus 로고    scopus 로고
    • Bortezomib induces selective depletion of alloreactive T lymphocytes and decreases the production of Th1 cytokines
    • Blanco B., Perez-Simon J.A., Sanchez-Abarca L.I., et al. Bortezomib induces selective depletion of alloreactive T lymphocytes and decreases the production of Th1 cytokines. Blood 2006, 107:3575-3583.
    • (2006) Blood , vol.107 , pp. 3575-3583
    • Blanco, B.1    Perez-Simon, J.A.2    Sanchez-Abarca, L.I.3
  • 13
    • 2542599273 scopus 로고    scopus 로고
    • Inhibition of acute graft-versus-host disease with retention of graft-versus-tumor effects by the proteasome inhibitor bortezomib
    • Sun K., Welniak L.A., Panoskaltsis-Mortari A., et al. Inhibition of acute graft-versus-host disease with retention of graft-versus-tumor effects by the proteasome inhibitor bortezomib. Proc Natl Acad Sci U S A 2004, 101:8120-8125.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 8120-8125
    • Sun, K.1    Welniak, L.A.2    Panoskaltsis-Mortari, A.3
  • 14
    • 27644477944 scopus 로고    scopus 로고
    • Differential effects of proteasome inhibition by bortezomib on murine acute graft-versus-host disease (GVHD): delayed administration of bortezomib results in increased GVHD-dependent gastrointestinal toxicity
    • Sun K., Wilkins D.E., Anver M.R., et al. Differential effects of proteasome inhibition by bortezomib on murine acute graft-versus-host disease (GVHD): delayed administration of bortezomib results in increased GVHD-dependent gastrointestinal toxicity. Blood 2005, 106:3293-3299.
    • (2005) Blood , vol.106 , pp. 3293-3299
    • Sun, K.1    Wilkins, D.E.2    Anver, M.R.3
  • 15
    • 30444458109 scopus 로고    scopus 로고
    • NF-kappaB as a target for the prevention of graft-versus-host disease: comparative efficacy of bortezomib and PS-1145
    • Vodanovic-Jankovic S., Hari P., Jacobs P., Komorowski R., Drobyski W.R. NF-kappaB as a target for the prevention of graft-versus-host disease: comparative efficacy of bortezomib and PS-1145. Blood 2006, 107:827-834.
    • (2006) Blood , vol.107 , pp. 827-834
    • Vodanovic-Jankovic, S.1    Hari, P.2    Jacobs, P.3    Komorowski, R.4    Drobyski, W.R.5
  • 16
    • 0038240386 scopus 로고    scopus 로고
    • The proteasome inhibitor PS-341 sensitizes neoplastic cells to TRAIL-mediated apoptosis by reducing levels of c-FLIP
    • Sayers T.J., Brooks A.D., Koh C.Y., et al. The proteasome inhibitor PS-341 sensitizes neoplastic cells to TRAIL-mediated apoptosis by reducing levels of c-FLIP. Blood 2003, 102:303-310.
    • (2003) Blood , vol.102 , pp. 303-310
    • Sayers, T.J.1    Brooks, A.D.2    Koh, C.Y.3
  • 17
    • 40449100492 scopus 로고    scopus 로고
    • Sensitization of tumor cells to NK cell-mediated killing by proteasome inhibition
    • Hallett W.H., Ames E., Motarjemi M., et al. Sensitization of tumor cells to NK cell-mediated killing by proteasome inhibition. JImmunol 2008, 180:163-170.
    • (2008) JImmunol , vol.180 , pp. 163-170
    • Hallett, W.H.1    Ames, E.2    Motarjemi, M.3
  • 18
    • 59649118271 scopus 로고    scopus 로고
    • Primitive quiescent CD34+ cells in chronic myeloid leukemia are targeted by invitro expanded natural killer cells, which are functionally enhanced by bortezomib
    • Yong A.S., Keyvanfar K., Hensel N., et al. Primitive quiescent CD34+ cells in chronic myeloid leukemia are targeted by invitro expanded natural killer cells, which are functionally enhanced by bortezomib. Blood 2009, 113:875-882.
    • (2009) Blood , vol.113 , pp. 875-882
    • Yong, A.S.1    Keyvanfar, K.2    Hensel, N.3
  • 19
    • 34250332128 scopus 로고    scopus 로고
    • The proteasome inhibitor PS-341 (bortezomib) up-regulates DR5 expression leading to induction of apoptosis and enhancement of TRAIL-induced apoptosis despite up-regulation of c-FLIP and survivin expression in human NSCLC cells
    • Liu X., Yue P., Chen S., et al. The proteasome inhibitor PS-341 (bortezomib) up-regulates DR5 expression leading to induction of apoptosis and enhancement of TRAIL-induced apoptosis despite up-regulation of c-FLIP and survivin expression in human NSCLC cells. Cancer Res 2007, 67:4981-4988.
    • (2007) Cancer Res , vol.67 , pp. 4981-4988
    • Liu, X.1    Yue, P.2    Chen, S.3
  • 20
    • 33645776929 scopus 로고    scopus 로고
    • Immunosensitization of tumor cells to dendritic cell-activated immune responses with the proteasome inhibitor bortezomib (PS-341, Velcade)
    • Schumacher L.Y., Vo D.D., Garban H.J., et al. Immunosensitization of tumor cells to dendritic cell-activated immune responses with the proteasome inhibitor bortezomib (PS-341, Velcade). JImmunol 2006, 176:4757-4765.
    • (2006) JImmunol , vol.176 , pp. 4757-4765
    • Schumacher, L.Y.1    Vo, D.D.2    Garban, H.J.3
  • 21
    • 33746917919 scopus 로고    scopus 로고
    • Bortezomib and depsipeptide sensitize tumors to tumor necrosis factor-related apoptosis-inducing ligand: a novel method to potentiate natural killer cell tumor cytotoxicity
    • Lundqvist A., Abrams S.I., Schrump D.S., et al. Bortezomib and depsipeptide sensitize tumors to tumor necrosis factor-related apoptosis-inducing ligand: a novel method to potentiate natural killer cell tumor cytotoxicity. Cancer Res 2006, 66:7317-7325.
    • (2006) Cancer Res , vol.66 , pp. 7317-7325
    • Lundqvist, A.1    Abrams, S.I.2    Schrump, D.S.3
  • 22
    • 0027980319 scopus 로고
    • Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules
    • Rock K.L., Gramm C., Rothstein L., et al. Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules. Cell 1994, 78:761-771.
    • (1994) Cell , vol.78 , pp. 761-771
    • Rock, K.L.1    Gramm, C.2    Rothstein, L.3
  • 23
    • 34249650184 scopus 로고    scopus 로고
    • Bortezomib enhances dendritic cell (DC)-mediated induction of immunity to human myeloma via exposure of cell surface heat shock protein 90 on dying tumor cells: therapeutic implications
    • Spisek R., Charalambous A., Mazumder A., Vesole D.H., Jagannath S., Dhodapkar M.V. Bortezomib enhances dendritic cell (DC)-mediated induction of immunity to human myeloma via exposure of cell surface heat shock protein 90 on dying tumor cells: therapeutic implications. Blood 2007, 109:4839-4845.
    • (2007) Blood , vol.109 , pp. 4839-4845
    • Spisek, R.1    Charalambous, A.2    Mazumder, A.3    Vesole, D.H.4    Jagannath, S.5    Dhodapkar, M.V.6
  • 24
    • 70449723162 scopus 로고    scopus 로고
    • Bortezomib, tacrolimus, and methotrexate for prophylaxis of graft-versus-host disease after reduced-intensity conditioning allogeneic stem cell transplantation from HLA-mismatched unrelated donors
    • Koreth J., Stevenson K.E., Kim H.T., et al. Bortezomib, tacrolimus, and methotrexate for prophylaxis of graft-versus-host disease after reduced-intensity conditioning allogeneic stem cell transplantation from HLA-mismatched unrelated donors. Blood 2009, 114:3956-3959.
    • (2009) Blood , vol.114 , pp. 3956-3959
    • Koreth, J.1    Stevenson, K.E.2    Kim, H.T.3
  • 25
    • 78649911512 scopus 로고    scopus 로고
    • Have we made progress in the management of chronic graft-vs-host disease?
    • Lee S.J. Have we made progress in the management of chronic graft-vs-host disease?. Best Pract Res Clin Haematol 2010, 23:529-535.
    • (2010) Best Pract Res Clin Haematol , vol.23 , pp. 529-535
    • Lee, S.J.1
  • 26
    • 33646685024 scopus 로고    scopus 로고
    • Bortezomib after dose-reduced allogeneic stem cell transplantation for multiple myeloma to enhance or maintain remission status
    • Kroger N., Zabelina T., Ayuk F., et al. Bortezomib after dose-reduced allogeneic stem cell transplantation for multiple myeloma to enhance or maintain remission status. Exp Hematol 2006, 34:770-775.
    • (2006) Exp Hematol , vol.34 , pp. 770-775
    • Kroger, N.1    Zabelina, T.2    Ayuk, F.3
  • 27
    • 51649122311 scopus 로고    scopus 로고
    • Differential effects of donor T-cell cytokines on outcome with continuous bortezomib administration after allogeneic bone marrow transplantation
    • Sun K., Li M., Sayers T.J., Welniak L.A., Murphy W.J. Differential effects of donor T-cell cytokines on outcome with continuous bortezomib administration after allogeneic bone marrow transplantation. Blood 2008, 112:1522-1529.
    • (2008) Blood , vol.112 , pp. 1522-1529
    • Sun, K.1    Li, M.2    Sayers, T.J.3    Welniak, L.A.4    Murphy, W.J.5
  • 28
    • 67650355477 scopus 로고    scopus 로고
    • Bortezomib treatment and regulatory T-cell depletion enhance the antitumor effects of adoptively infused NK cells
    • Lundqvist A., Yokoyama H., Smith A., Berg M., Childs R. Bortezomib treatment and regulatory T-cell depletion enhance the antitumor effects of adoptively infused NK cells. Blood 2009, 113:6120-6127.
    • (2009) Blood , vol.113 , pp. 6120-6127
    • Lundqvist, A.1    Yokoyama, H.2    Smith, A.3    Berg, M.4    Childs, R.5
  • 29
    • 10744233452 scopus 로고    scopus 로고
    • Phase 1 study of low-dose prolonged exposure schedules of the hypomethylating agent 5-aza-2'-deoxycytidine (decitabine) in hematopoietic malignancies
    • Issa J.P., Garcia-Manero G., Giles F.J., et al. Phase 1 study of low-dose prolonged exposure schedules of the hypomethylating agent 5-aza-2'-deoxycytidine (decitabine) in hematopoietic malignancies. Blood 2004, 103:1635-1640.
    • (2004) Blood , vol.103 , pp. 1635-1640
    • Issa, J.P.1    Garcia-Manero, G.2    Giles, F.J.3
  • 30
    • 62849104641 scopus 로고    scopus 로고
    • Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes: a randomised, open-label, phase III study
    • Fenaux P., Mufti G.J., Hellstrom-Lindberg E., et al. Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes: a randomised, open-label, phase III study. Lancet Oncol 2009, 10:223-232.
    • (2009) Lancet Oncol , vol.10 , pp. 223-232
    • Fenaux, P.1    Mufti, G.J.2    Hellstrom-Lindberg, E.3
  • 31
    • 0344211845 scopus 로고    scopus 로고
    • Long-term follow-up of a phase I study of high-dose decitabine, busulfan, and cyclophosphamide plus allogeneic transplantation for the treatment of patients with leukemias
    • de Lima M., Ravandi F., Shahjahan M., et al. Long-term follow-up of a phase I study of high-dose decitabine, busulfan, and cyclophosphamide plus allogeneic transplantation for the treatment of patients with leukemias. Cancer 2003, 97:1242-1247.
    • (2003) Cancer , vol.97 , pp. 1242-1247
    • de Lima, M.1    Ravandi, F.2    Shahjahan, M.3
  • 32
    • 0021133490 scopus 로고
    • Modulation of HLA-DR antigens expression in human myeloid leukaemia cells by cytarabine and 5-aza-2'-deoxycytidine
    • Pinto A., Maio M., Attadia V., Zappacosta S., Cimino R. Modulation of HLA-DR antigens expression in human myeloid leukaemia cells by cytarabine and 5-aza-2'-deoxycytidine. Lancet 1984, 2:867-868.
    • (1984) Lancet , vol.2 , pp. 867-868
    • Pinto, A.1    Maio, M.2    Attadia, V.3    Zappacosta, S.4    Cimino, R.5
  • 33
    • 0021160287 scopus 로고
    • 5-Aza-2'-deoxycytidine induces terminal differentiation of leukemic blasts from patients with acute myeloid leukemias
    • Pinto A., Attadia V., Fusco A., Ferrara F., Spada O.A., Di Fiore P.P. 5-Aza-2'-deoxycytidine induces terminal differentiation of leukemic blasts from patients with acute myeloid leukemias. Blood 1984, 64:922-929.
    • (1984) Blood , vol.64 , pp. 922-929
    • Pinto, A.1    Attadia, V.2    Fusco, A.3    Ferrara, F.4    Spada, O.A.5    Di Fiore, P.P.6
  • 34
    • 63849084718 scopus 로고    scopus 로고
    • Hypomethylating drugs convert HA-1-negative solid tumors into targets for stem cell-based immunotherapy
    • Hambach L., Ling K.W., Pool J., et al. Hypomethylating drugs convert HA-1-negative solid tumors into targets for stem cell-based immunotherapy. Blood 2009, 113:2715-2722.
    • (2009) Blood , vol.113 , pp. 2715-2722
    • Hambach, L.1    Ling, K.W.2    Pool, J.3
  • 35
    • 65649120045 scopus 로고    scopus 로고
    • Low-dose azacitidine after allogeneic stem cell transplantation for acute leukemia
    • Jabbour E., Giralt S., Kantarjian H., et al. Low-dose azacitidine after allogeneic stem cell transplantation for acute leukemia. Cancer 2009, 115:1899-1905.
    • (2009) Cancer , vol.115 , pp. 1899-1905
    • Jabbour, E.1    Giralt, S.2    Kantarjian, H.3
  • 36
    • 34249289754 scopus 로고    scopus 로고
    • Simultaneously optimizing dose and schedule of a new cytotoxic agent
    • Braun T.M., Thall P.F., Nguyen H., de Lima M. Simultaneously optimizing dose and schedule of a new cytotoxic agent. Clin Trials 2007, 4:113-124.
    • (2007) Clin Trials , vol.4 , pp. 113-124
    • Braun, T.M.1    Thall, P.F.2    Nguyen, H.3    de Lima, M.4
  • 37
    • 79956017109 scopus 로고    scopus 로고
    • Clofarabine +/- fludarabine with once daily i.v. busulfan as pretransplant conditioning therapy for advanced myeloid leukemia and MDS
    • Andersson B.S., Valdez B.C., de Lima M., et al. Clofarabine +/- fludarabine with once daily i.v. busulfan as pretransplant conditioning therapy for advanced myeloid leukemia and MDS. Biol Blood Marrow Transplant 2010, 17:893-900.
    • (2010) Biol Blood Marrow Transplant , vol.17 , pp. 893-900
    • Andersson, B.S.1    Valdez, B.C.2    de Lima, M.3
  • 38
    • 84858002418 scopus 로고    scopus 로고
    • Azacitidine for treatment of imminent relapse in MDS or AML patients after allogeneic HSCT: results of the RELAZA trial
    • Platzbecker U., Wermke M., Radke J., et al. Azacitidine for treatment of imminent relapse in MDS or AML patients after allogeneic HSCT: results of the RELAZA trial. Leukemia 2011.
    • (2011) Leukemia
    • Platzbecker, U.1    Wermke, M.2    Radke, J.3
  • 39
    • 74949115148 scopus 로고    scopus 로고
    • Immunomodulatory effect of 5-azacytidine (5-azaC): potential role in the transplantation setting
    • Sanchez-Abarca L.I., Gutierrez-Cosio S., Santamaria C., et al. Immunomodulatory effect of 5-azacytidine (5-azaC): potential role in the transplantation setting. Blood 2010, 115:107-121.
    • (2010) Blood , vol.115 , pp. 107-121
    • Sanchez-Abarca, L.I.1    Gutierrez-Cosio, S.2    Santamaria, C.3
  • 40
    • 77955900102 scopus 로고    scopus 로고
    • Invivo administration of hypomethylating agents mitigate graft-versus-host disease without sacrificing graft-versus-leukemia
    • Choi J., Ritchey J., Prior J.L., et al. Invivo administration of hypomethylating agents mitigate graft-versus-host disease without sacrificing graft-versus-leukemia. Blood 2010, 116:129-139.
    • (2010) Blood , vol.116 , pp. 129-139
    • Choi, J.1    Ritchey, J.2    Prior, J.L.3
  • 41
    • 0035839136 scopus 로고    scopus 로고
    • Translating the histone code
    • Jenuwein T., Allis C.D. Translating the histone code. Science 2001, 293:1074-1080.
    • (2001) Science , vol.293 , pp. 1074-1080
    • Jenuwein, T.1    Allis, C.D.2
  • 43
    • 39749127166 scopus 로고    scopus 로고
    • The Rpd3/Hda1 family of lysine deacetylases: from bacteria and yeast to mice and men
    • Yang X.J., Seto E. The Rpd3/Hda1 family of lysine deacetylases: from bacteria and yeast to mice and men. Nat Rev Mol Cell Biol 2008, 9:206-218.
    • (2008) Nat Rev Mol Cell Biol , vol.9 , pp. 206-218
    • Yang, X.J.1    Seto, E.2
  • 44
    • 36148950997 scopus 로고    scopus 로고
    • FDA approval summary: vorinostat for treatment of advanced primary cutaneous T-cell lymphoma
    • Mann B.S., Johnson J.R., Cohen M.H., Justice R., Pazdur R. FDA approval summary: vorinostat for treatment of advanced primary cutaneous T-cell lymphoma. Oncologist 2007, 12:1247-1252.
    • (2007) Oncologist , vol.12 , pp. 1247-1252
    • Mann, B.S.1    Johnson, J.R.2    Cohen, M.H.3    Justice, R.4    Pazdur, R.5
  • 45
    • 33845996135 scopus 로고    scopus 로고
    • Phase 2 trial of oral vorinostat (suberoylanilide hydroxamic acid, SAHA) for refractory cutaneous T-cell lymphoma (CTCL)
    • Duvic M., Talpur R., Ni X., et al. Phase 2 trial of oral vorinostat (suberoylanilide hydroxamic acid, SAHA) for refractory cutaneous T-cell lymphoma (CTCL). Blood 2007, 109:31-39.
    • (2007) Blood , vol.109 , pp. 31-39
    • Duvic, M.1    Talpur, R.2    Ni, X.3
  • 46
    • 0037022598 scopus 로고    scopus 로고
    • The antitumor histone deacetylase inhibitor suberoylanilide hydroxamic acid exhibits antiinflammatory properties via suppression of cytokines
    • Leoni F., Zaliani A., Bertolini G., et al. The antitumor histone deacetylase inhibitor suberoylanilide hydroxamic acid exhibits antiinflammatory properties via suppression of cytokines. Proc Natl Acad Sci USA 2002, 99:2995-3000.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 2995-3000
    • Leoni, F.1    Zaliani, A.2    Bertolini, G.3
  • 47
    • 33646495294 scopus 로고    scopus 로고
    • The histone deacetylase inhibitor ITF2357 reduces production of pro-inflammatory cytokines invitro and systemic inflammation invivo
    • Leoni F., Fossati G., Lewis E.C., et al. The histone deacetylase inhibitor ITF2357 reduces production of pro-inflammatory cytokines invitro and systemic inflammation invivo. Mol Med 2005, 11:1-15.
    • (2005) Mol Med , vol.11 , pp. 1-15
    • Leoni, F.1    Fossati, G.2    Lewis, E.C.3
  • 48
    • 1642415712 scopus 로고    scopus 로고
    • Histone deacetylase inhibitor suberoylanilide hydroxamic acid reduces acute graft-versus-host disease and preserves graft-versus-leukemia effect
    • Reddy P., Maeda Y., Hotary K., et al. Histone deacetylase inhibitor suberoylanilide hydroxamic acid reduces acute graft-versus-host disease and preserves graft-versus-leukemia effect. Proc Natl Acad Sci USA 2004, 101:3921-3926.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 3921-3926
    • Reddy, P.1    Maeda, Y.2    Hotary, K.3
  • 49
    • 46749144173 scopus 로고    scopus 로고
    • Histone deacetylase inhibition modulates indoleamine 2,3-dioxygenase-dependent DC functions and regulates experimental graft-versus-host disease in mice
    • Reddy P., Sun Y., Toubai T., et al. Histone deacetylase inhibition modulates indoleamine 2,3-dioxygenase-dependent DC functions and regulates experimental graft-versus-host disease in mice. J Clin Invest 2008, 118:2562-2573.
    • (2008) J Clin Invest , vol.118 , pp. 2562-2573
    • Reddy, P.1    Sun, Y.2    Toubai, T.3
  • 50
    • 0037330279 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors modulate renal disease in the MRL-lpr/lpr mouse
    • Mishra N., Reilly C.M., Brown D.R., Ruiz P., Gilkeson G.S. Histone deacetylase inhibitors modulate renal disease in the MRL-lpr/lpr mouse. J Clin Invest 2003, 111:539-552.
    • (2003) J Clin Invest , vol.111 , pp. 539-552
    • Mishra, N.1    Reilly, C.M.2    Brown, D.R.3    Ruiz, P.4    Gilkeson, G.S.5
  • 51
    • 0037441885 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors: a new class of immunosuppressors targeting a novel signal pathway essential for CD154 expression
    • Skov S., Rieneck K., Bovin L.F., et al. Histone deacetylase inhibitors: a new class of immunosuppressors targeting a novel signal pathway essential for CD154 expression. Blood 2003, 101:1430-1438.
    • (2003) Blood , vol.101 , pp. 1430-1438
    • Skov, S.1    Rieneck, K.2    Bovin, L.F.3
  • 52
    • 33645775726 scopus 로고    scopus 로고
    • Histone hyperacetylation is associated with amelioration of experimental colitis in mice
    • Glauben R., Batra A., Fedke I., et al. Histone hyperacetylation is associated with amelioration of experimental colitis in mice. JImmunol 2006, 176:5015-5022.
    • (2006) JImmunol , vol.176 , pp. 5015-5022
    • Glauben, R.1    Batra, A.2    Fedke, I.3
  • 53
    • 42549114401 scopus 로고    scopus 로고
    • Histone deacetylases: novel targets for prevention of colitis-associated cancer in mice
    • Glauben R., Batra A., Stroh T., et al. Histone deacetylases: novel targets for prevention of colitis-associated cancer in mice. Gut 2008, 57:613-622.
    • (2008) Gut , vol.57 , pp. 613-622
    • Glauben, R.1    Batra, A.2    Stroh, T.3
  • 54
    • 35948980739 scopus 로고    scopus 로고
    • Deacetylase inhibition promotes the generation and function of regulatory T cells
    • Tao R., de Zoeten E.F., Ozkaynak E., et al. Deacetylase inhibition promotes the generation and function of regulatory T cells. Nat Med 2007, 13:1299-1307.
    • (2007) Nat Med , vol.13 , pp. 1299-1307
    • Tao, R.1    de Zoeten, E.F.2    Ozkaynak, E.3
  • 55
    • 33646710170 scopus 로고    scopus 로고
    • Reduction of graft-versus-host disease by histone deacetylase inhibitor suberonylanilide hydroxamic acid is associated with modulation of inflammatory cytokine milieu and involves inhibition of STAT1
    • Leng C., Gries M., Ziegler J., et al. Reduction of graft-versus-host disease by histone deacetylase inhibitor suberonylanilide hydroxamic acid is associated with modulation of inflammatory cytokine milieu and involves inhibition of STAT1. Exp Hematol 2006, 34:776-787.
    • (2006) Exp Hematol , vol.34 , pp. 776-787
    • Leng, C.1    Gries, M.2    Ziegler, J.3
  • 56
    • 34247573902 scopus 로고    scopus 로고
    • Graft-versus-host disease
    • Shlomchik W.D. Graft-versus-host disease. Nat Rev Immunol 2007, 7:340-352.
    • (2007) Nat Rev Immunol , vol.7 , pp. 340-352
    • Shlomchik, W.D.1
  • 58
    • 70349737858 scopus 로고    scopus 로고
    • Cutting edge: negative regulation of dendritic cells through acetylation of the nonhistone protein STAT-3
    • Sun Y., Chin Y.E., Weisiger E., et al. Cutting edge: negative regulation of dendritic cells through acetylation of the nonhistone protein STAT-3. J Immunol 2009, 182:5899-5903.
    • (2009) J Immunol , vol.182 , pp. 5899-5903
    • Sun, Y.1    Chin, Y.E.2    Weisiger, E.3
  • 59
    • 0141537035 scopus 로고    scopus 로고
    • Lowered-intensity preparative regimen for allogeneic stem cell transplantation delays acute graft-versus-host disease but does not improve outcome for advanced hematologic malignancy
    • Levine J.E., Uberti J.P., Ayash L., et al. Lowered-intensity preparative regimen for allogeneic stem cell transplantation delays acute graft-versus-host disease but does not improve outcome for advanced hematologic malignancy. Biol Blood Marrow Transplant 2003, 9:189-197.
    • (2003) Biol Blood Marrow Transplant , vol.9 , pp. 189-197
    • Levine, J.E.1    Uberti, J.P.2    Ayash, L.3


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