메뉴 건너뛰기




Volumn 113, Issue 12, 2009, Pages 2715-2722

Hypomethylating drugs convert HA-1 negative solid tumors into targets for stem cell based immunotherapy

Author keywords

[No Author keywords available]

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; DNA; HISTONE; TRICHOSTATIN A;

EID: 63849084718     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2008-05-158956     Document Type: Article
Times cited : (45)

References (43)
  • 1
    • 9444243905 scopus 로고    scopus 로고
    • Evidence for a graft-versus-tumor effect in a patient treated with marrow ablative chemotherapy and allogeneic bone marrow transplantation for breast cancer
    • Eibl B, Schwaighofer H, Nachbaur D, et al. Evidence for a graft-versus-tumor effect in a patient treated with marrow ablative chemotherapy and allogeneic bone marrow transplantation for breast cancer. Blood. 1996;88:1501-1508.
    • (1996) Blood , vol.88 , pp. 1501-1508
    • Eibl, B.1    Schwaighofer, H.2    Nachbaur, D.3
  • 2
    • 0036624786 scopus 로고    scopus 로고
    • Nonmyeloablative conditioning followed by hematopoietic cell allografting and donor lymphocyte infusions for patients with metastatic renal and breast cancer
    • Bregni M, Dodero A, Peccatori J, et al. Nonmyeloablative conditioning followed by hematopoietic cell allografting and donor lymphocyte infusions for patients with metastatic renal and breast cancer. Blood. 2002;99:4234-4236.
    • (2002) Blood , vol.99 , pp. 4234-4236
    • Bregni, M.1    Dodero, A.2    Peccatori, J.3
  • 3
    • 0034648702 scopus 로고    scopus 로고
    • Regression of metastatic renal-cell carcinoma after non-myeloablative allogeneic peripheral-blood stem-cell transplantation
    • Childs R, Chernoff A, Contentin N, et al. Regression of metastatic renal-cell carcinoma after non-myeloablative allogeneic peripheral-blood stem-cell transplantation. N Engl J Med. 2000;343:750-758.
    • (2000) N Engl J Med , vol.343 , pp. 750-758
    • Childs, R.1    Chernoff, A.2    Contentin, N.3
  • 4
    • 14844286852 scopus 로고    scopus 로고
    • Immunotherapy of cancer through targeting of minor histocompatibility antigens
    • Hambach L, Goulmy E. Immunotherapy of cancer through targeting of minor histocompatibility antigens. Curr Opin Immunol. 2005;17:202-210.
    • (2005) Curr Opin Immunol , vol.17 , pp. 202-210
    • Hambach, L.1    Goulmy, E.2
  • 5
    • 0029866282 scopus 로고    scopus 로고
    • Human minor histocompatibility antigens
    • Goulmy E. Human minor histocompatibility antigens. Curr Opin Immunol. 1996;8:75-81.
    • (1996) Curr Opin Immunol , vol.8 , pp. 75-81
    • Goulmy, E.1
  • 6
    • 0026728223 scopus 로고
    • Tissue distribution of human minor histocompatibility antigens: Ubiquitous versus restricted tissue distribution indicated heterogenity among human cytotoxic T lymphocyte-defined non-MHC antigens
    • de Bueger M, Bakker A, van Rood J, van der Woude F, Goulmy E. Tissue distribution of human minor histocompatibility antigens: ubiquitous versus restricted tissue distribution indicated heterogenity among human cytotoxic T lymphocyte-defined non-MHC antigens. J Immunol. 1992;149:1788-1794.
    • (1992) J Immunol , vol.149 , pp. 1788-1794
    • de Bueger, M.1    Bakker, A.2    van Rood, J.3    van der Woude, F.4    Goulmy, E.5
  • 7
    • 0036107517 scopus 로고    scopus 로고
    • In situ dissection of the graft-versus-host activities of cytotoxic T cells specific for minor histocompatibility antigens
    • Dickinson A, Wang X, Sviland L, et al. In situ dissection of the graft-versus-host activities of cytotoxic T cells specific for minor histocompatibility antigens. Nat Med. 2002;8:410-414.
    • (2002) Nat Med , vol.8 , pp. 410-414
    • Dickinson, A.1    Wang, X.2    Sviland, L.3
  • 8
    • 0037025999 scopus 로고    scopus 로고
    • The hematopoietic system-specific minor histocompatibility antigen HA-1 shows aberrant expression in epithelial cancer cells
    • Klein C, Wilke M, Pool J, et al. The hematopoietic system-specific minor histocompatibility antigen HA-1 shows aberrant expression in epithelial cancer cells. J Exp Med. 2002;196:359-368.
    • (2002) J Exp Med , vol.196 , pp. 359-368
    • Klein, C.1    Wilke, M.2    Pool, J.3
  • 9
    • 0037091033 scopus 로고    scopus 로고
    • Expression of minor histocompatibility antigen, HA-1, in solid tumor cells
    • Fuji N, Hiraki A, Ikeda K, et al. Expression of minor histocompatibility antigen, HA-1, in solid tumor cells. Transplantation. 2002;73:1137-1141.
    • (2002) Transplantation , vol.73 , pp. 1137-1141
    • Fuji, N.1    Hiraki, A.2    Ikeda, K.3
  • 10
    • 5444224775 scopus 로고    scopus 로고
    • Allogeneic hematopoietic cell transplantation for metastatic renal cell carcinoma after nonmyeloablative conditioning: Toxicity, clinical response, and immunological response to minor histocompatibility antigens
    • Tykodi S, Warren E, Thompson J, et al. Allogeneic hematopoietic cell transplantation for metastatic renal cell carcinoma after nonmyeloablative conditioning: toxicity, clinical response, and immunological response to minor histocompatibility antigens. Clin Cancer Res. 2004;10:7799-7811.
    • (2004) Clin Cancer Res , vol.10 , pp. 7799-7811
    • Tykodi, S.1    Warren, E.2    Thompson, J.3
  • 11
    • 52649112078 scopus 로고    scopus 로고
    • Targeting a single mismatched minor histocompatibility antigen with tumor-restricted expression eradicates human solid tumors
    • Hambach L, Vermeij M, Buser A, et al. Targeting a single mismatched minor histocompatibility antigen with tumor-restricted expression eradicates human solid tumors. Blood. 2008;112:1844-1852.
    • (2008) Blood , vol.112 , pp. 1844-1852
    • Hambach, L.1    Vermeij, M.2    Buser, A.3
  • 12
    • 6844237658 scopus 로고    scopus 로고
    • The minor histocompatibility antigen HA-1: A diallelic gene with a single amino acid polymorphism
    • den Haan J, Meadows L, Wang W, et al. The minor histocompatibility antigen HA-1: a diallelic gene with a single amino acid polymorphism. Science. 1998;279:1054-1057.
    • (1998) Science , vol.279 , pp. 1054-1057
    • den Haan, J.1    Meadows, L.2    Wang, W.3
  • 13
    • 0031691483 scopus 로고    scopus 로고
    • Genomic Identification of the minor histocompatibility antigen HA-1 locus by allele-specific PCR
    • Wilke M, Pool J, den Haan J, Goulmy E. Genomic Identification of the minor histocompatibility antigen HA-1 locus by allele-specific PCR. Tissue Antigens. 1998;52:312-317.
    • (1998) Tissue Antigens , vol.52 , pp. 312-317
    • Wilke, M.1    Pool, J.2    den Haan, J.3    Goulmy, E.4
  • 14
    • 34347363145 scopus 로고    scopus 로고
    • Phenotype frequencies of autosomal minor histocompatibility antigens display significant differences among populations
    • Spierings E, Hendriks M, Absi L, et al. Phenotype frequencies of autosomal minor histocompatibility antigens display significant differences among populations. PLoS Genet. 2007;3:e103.
    • (2007) PLoS Genet , vol.3
    • Spierings, E.1    Hendriks, M.2    Absi, L.3
  • 15
    • 0035839057 scopus 로고    scopus 로고
    • The role of DNA methylation in mammalian epigenetics
    • Jones PA, Takai D. The role of DNA methylation in mammalian epigenetics. Science. 2001;293:1068-1070.
    • (2001) Science , vol.293 , pp. 1068-1070
    • Jones, P.A.1    Takai, D.2
  • 16
    • 33947315736 scopus 로고    scopus 로고
    • Cancer epigenomics: DNA methylomes and histone-modification maps
    • Esteller M. Cancer epigenomics: DNA methylomes and histone-modification maps. Nat Rev Genet. 2007;8:286-298.
    • (2007) Nat Rev Genet , vol.8 , pp. 286-298
    • Esteller, M.1
  • 17
    • 2642531973 scopus 로고    scopus 로고
    • Epigenetics in human disease and prospects for epigenetic therapy
    • Egger G, Liang G, Aparicio A, Jones PA. Epigenetics in human disease and prospects for epigenetic therapy. Nature. 2004;429:457-463.
    • (2004) Nature , vol.429 , pp. 457-463
    • Egger, G.1    Liang, G.2    Aparicio, A.3    Jones, P.A.4
  • 18
    • 33644856123 scopus 로고    scopus 로고
    • Epigenetic therapy of cancer: Past, present and future
    • Yoo CB, Jones PA. Epigenetic therapy of cancer: past, present and future. Nat Rev Drug Discov. 2006;5:37-50.
    • (2006) Nat Rev Drug Discov , vol.5 , pp. 37-50
    • Yoo, C.B.1    Jones, P.A.2
  • 19
    • 10844289762 scopus 로고    scopus 로고
    • Intratumor heterogeneity of cancer/testis antigens expression in human cutaneous melanoma is methylation-regulated and functionally reverted by 5-aza-2′-deoxycytidine
    • Sigalotti L, Fratta E, Coral S, et al. Intratumor heterogeneity of cancer/testis antigens expression in human cutaneous melanoma is methylation-regulated and functionally reverted by 5-aza-2′-deoxycytidine. Cancer Res. 2004;64:9167-9171.
    • (2004) Cancer Res , vol.64 , pp. 9167-9171
    • Sigalotti, L.1    Fratta, E.2    Coral, S.3
  • 20
    • 0242539831 scopus 로고    scopus 로고
    • Epigenetic targets for immune intervention in human malignancies
    • Maio M, Coral S, Fratta E, Altomonte M, Sigalotti L. Epigenetic targets for immune intervention in human malignancies. Oncogene. 2003;22:6484-6488.
    • (2003) Oncogene , vol.22 , pp. 6484-6488
    • Maio, M.1    Coral, S.2    Fratta, E.3    Altomonte, M.4    Sigalotti, L.5
  • 21
    • 31544432509 scopus 로고    scopus 로고
    • De novo induction of a cancer/testis antigen by 5-aza-2′- deoxycytidine augments adoptive immunotherapy in a murine tumor model
    • Guo ZS, Hong JA, Irvine KR, et al. De novo induction of a cancer/testis antigen by 5-aza-2′- deoxycytidine augments adoptive immunotherapy in a murine tumor model. Cancer Res. 2006;66:1105-1113.
    • (2006) Cancer Res , vol.66 , pp. 1105-1113
    • Guo, Z.S.1    Hong, J.A.2    Irvine, K.R.3
  • 22
    • 50349087907 scopus 로고    scopus 로고
    • Intertumor and intratumor NY-ESO-1 expression heterogeneity is associated with promoter-specific and global DNA methylation status in ovarian cancer
    • Woloszynska-Read A, Mhawech-Fauceglia P, Yu J, Odunsi K, Karpf AR. Intertumor and intratumor NY-ESO-1 expression heterogeneity is associated with promoter-specific and global DNA methylation status in ovarian cancer. Clin Cancer Res. 2008;14:3283-3290.
    • (2008) Clin Cancer Res , vol.14 , pp. 3283-3290
    • Woloszynska-Read, A.1    Mhawech-Fauceglia, P.2    Yu, J.3    Odunsi, K.4    Karpf, A.R.5
  • 23
    • 0035886022 scopus 로고    scopus 로고
    • Reexpression of HLA class I antigens and restoration of antigen-specific CTL response in melanoma cells following 5-aza-2′-deoxycytidinetreatment
    • Serrano A, Tanzarella S, Lionello I, et al. Reexpression of HLA class I antigens and restoration of antigen-specific CTL response in melanoma cells following 5-aza-2′-deoxycytidinetreatment. Int J Cancer. 2001;94:243-251.
    • (2001) Int J Cancer , vol.94 , pp. 243-251
    • Serrano, A.1    Tanzarella, S.2    Lionello, I.3
  • 24
    • 34250621776 scopus 로고    scopus 로고
    • Functional up-regulation of human leukocyte antigen class I antigens expression by 5-aza-2′- deoxycytidine in cutaneous melanoma: Immunotherapeutic implications
    • Fonsatti E, Nicolay HJ, Sigalotti L, et al. Functional up-regulation of human leukocyte antigen class I antigens expression by 5-aza-2′- deoxycytidine in cutaneous melanoma: immunotherapeutic implications. Clin Cancer Res. 2007;13:3333-3338.
    • (2007) Clin Cancer Res , vol.13 , pp. 3333-3338
    • Fonsatti, E.1    Nicolay, H.J.2    Sigalotti, L.3
  • 25
    • 20844456960 scopus 로고    scopus 로고
    • Discovery of epigenetically masked tumor suppressor genes in endometrial cancer
    • Takai N, Kawamata N, Walsh CS, et al. Discovery of epigenetically masked tumor suppressor genes in endometrial cancer. Mol Cancer Res. 2005;3:261-269.
    • (2005) Mol Cancer Res , vol.3 , pp. 261-269
    • Takai, N.1    Kawamata, N.2    Walsh, C.S.3
  • 26
    • 34347206256 scopus 로고    scopus 로고
    • Auniform genomic minor histocompatibility antigen typing methodology and database designed to facilitate clinical applications
    • Spierings E, Drabbels J, Hendriks M, et al. Auniform genomic minor histocompatibility antigen typing methodology and database designed to facilitate clinical applications. PLoS ONE. 2006;1:e42.
    • (2006) PLoS ONE , vol.1
    • Spierings, E.1    Drabbels, J.2    Hendriks, M.3
  • 27
    • 0033120425 scopus 로고    scopus 로고
    • Feasibility of immunotherapy of relapsed leukemia with ex vivo-generated cytotoxic T lymphocytes specific for hematopoietic system-restricted minor histocompatibility antigens
    • Mutis T, Verdijk R, Schrama E, et al. Feasibility of immunotherapy of relapsed leukemia with ex vivo-generated cytotoxic T lymphocytes specific for hematopoietic system-restricted minor histocompatibility antigens. Blood. 1999;93:2336-2341.
    • (1999) Blood , vol.93 , pp. 2336-2341
    • Mutis, T.1    Verdijk, R.2    Schrama, E.3
  • 28
    • 0041966026 scopus 로고    scopus 로고
    • Identification of HLA class II-restricted H-Y specific T helper epitope evoking CD4+ T-helper cells in H-Y-mismatched transplantation
    • Spierings E, Vermeulen C, Vogt M, et al. Identification of HLA class II-restricted H-Y specific T helper epitope evoking CD4+ T-helper cells in H-Y-mismatched transplantation. Lancet. 2003;362:590-591.
    • (2003) Lancet , vol.362 , pp. 590-591
    • Spierings, E.1    Vermeulen, C.2    Vogt, M.3
  • 29
    • 0030608273 scopus 로고    scopus 로고
    • Nagase T, Seki N, Ishikawa K, et al. Prediction of the coding sequences of unidentified human genes, VI: The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain. DNA Res. 1996;3:321-354.
    • Nagase T, Seki N, Ishikawa K, et al. Prediction of the coding sequences of unidentified human genes, VI: The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain. DNA Res. 1996;3:321-354.
  • 30
    • 0034736108 scopus 로고    scopus 로고
    • Genomic organization of the human cholesterol-responsive ABC transporter ABCA7: Tandem linkage with the minor histocompatibility antigen HA-1 gene
    • Kaminski WE, Piehler A, Schmitz G. Genomic organization of the human cholesterol-responsive ABC transporter ABCA7: tandem linkage with the minor histocompatibility antigen HA-1 gene. Biochem Biophys Res Commun. 2000;278:782-789.
    • (2000) Biochem Biophys Res Commun , vol.278 , pp. 782-789
    • Kaminski, W.E.1    Piehler, A.2    Schmitz, G.3
  • 31
    • 0037133565 scopus 로고    scopus 로고
    • Comprehensive analysis of CpG islands in human chromosomes 21 and 22
    • Takai D, Jones PA. Comprehensive analysis of CpG islands in human chromosomes 21 and 22. Proc Natl Acad Sci USA. 2002;99:3740-3745.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 3740-3745
    • Takai, D.1    Jones, P.A.2
  • 32
    • 0345603004 scopus 로고    scopus 로고
    • The CpG island searcher: A new WWW resource
    • Takai D, Jones PA. The CpG island searcher: a new WWW resource. In Silico Biol. 2003;3:235-240.
    • (2003) In Silico Biol , vol.3 , pp. 235-240
    • Takai, D.1    Jones, P.A.2
  • 33
    • 33745125037 scopus 로고    scopus 로고
    • The diallelic locus encoding the minor histocompatibility antigen HA-1 is evolutionarily conserved
    • Wieles B, Pool J, Wilke M, et al. The diallelic locus encoding the minor histocompatibility antigen HA-1 is evolutionarily conserved. Tissue Antigens. 2006;68:62-65.
    • (2006) Tissue Antigens , vol.68 , pp. 62-65
    • Wieles, B.1    Pool, J.2    Wilke, M.3
  • 34
    • 37549060948 scopus 로고    scopus 로고
    • Concordant epigenetic silencing of transforming growth factor-beta signaling pathway genes occurs early in breast carcinogenesis
    • Hinshelwood RA, Huschtscha LI, Melki J, et al. Concordant epigenetic silencing of transforming growth factor-beta signaling pathway genes occurs early in breast carcinogenesis. Cancer Res. 2007;67:11517-11527.
    • (2007) Cancer Res , vol.67 , pp. 11517-11527
    • Hinshelwood, R.A.1    Huschtscha, L.I.2    Melki, J.3
  • 35
    • 0037112369 scopus 로고    scopus 로고
    • Histone H3-lysine 9 methylation is associated with aberrant gene silencing in cancer cells and is rapidly reversed by 5-aza-2'-deoxycytidine
    • Nguyen CT, Weisenberger DJ, Velicescu M, et al. Histone H3-lysine 9 methylation is associated with aberrant gene silencing in cancer cells and is rapidly reversed by 5-aza-2'-deoxycytidine. Cancer Res. 2002;62:6456-6461.
    • (2002) Cancer Res , vol.62 , pp. 6456-6461
    • Nguyen, C.T.1    Weisenberger, D.J.2    Velicescu, M.3
  • 36
    • 10744233452 scopus 로고    scopus 로고
    • Phase 1 study of low-dose prolonged exposure schedules of the hypomethylating agent 5-aza-2′- deoxycytidine (decitabine) in hematopoietic malignancies
    • Issa JP, Garcia-Manero G, Giles FJ, et al. Phase 1 study of low-dose prolonged exposure schedules of the hypomethylating agent 5-aza-2′- deoxycytidine (decitabine) in hematopoietic malignancies. Blood. 2004;103:1635-1640.
    • (2004) Blood , vol.103 , pp. 1635-1640
    • Issa, J.P.1    Garcia-Manero, G.2    Giles, F.J.3
  • 37
    • 33846011361 scopus 로고    scopus 로고
    • Results of a randomized study of 3 schedules of low-dose decitabine in higher-risk myelodysplastic syndrome and chronic myelomonocytic leukemia
    • Kantarjian H, Oki Y, Garcia-Manero G, et al. Results of a randomized study of 3 schedules of low-dose decitabine in higher-risk myelodysplastic syndrome and chronic myelomonocytic leukemia. Blood. 2007;109:52-57.
    • (2007) Blood , vol.109 , pp. 52-57
    • Kantarjian, H.1    Oki, Y.2    Garcia-Manero, G.3
  • 38
    • 55749110754 scopus 로고    scopus 로고
    • Demethylating agents in myeloid malignancies
    • Garcia-Manero G. Demethylating agents in myeloid malignancies. Curr Opin Oncol. 2008;20:705-710.
    • (2008) Curr Opin Oncol , vol.20 , pp. 705-710
    • Garcia-Manero, G.1
  • 39
    • 0344990164 scopus 로고    scopus 로고
    • Phase I trial of continuous infusion 5-aza-2′-deoxycytidine
    • Aparicio A, Eads CA, Leong LA, et al. Phase I trial of continuous infusion 5-aza-2′-deoxycytidine. Cancer Chemother Pharmacol. 2003;51:231-239.
    • (2003) Cancer Chemother Pharmacol , vol.51 , pp. 231-239
    • Aparicio, A.1    Eads, C.A.2    Leong, L.A.3
  • 40
    • 21244449980 scopus 로고    scopus 로고
    • Evaluation of a 7-day continuous intravenous infusion of decitabine: Inhibition of promoter-specific and global genomic DNA methylation
    • Samlowski WE, Leachman SA, Wade M, et al. Evaluation of a 7-day continuous intravenous infusion of decitabine: inhibition of promoter-specific and global genomic DNA methylation. J Clin Oncol. 2005;23:3897-3905.
    • (2005) J Clin Oncol , vol.23 , pp. 3897-3905
    • Samlowski, W.E.1    Leachman, S.A.2    Wade, M.3
  • 41
    • 63849282054 scopus 로고    scopus 로고
    • Bast R, Lyer R, Hu W, et al. A phase IIa study of a sequential regimen using azacitidine to reverse platinum resistance to carboplatin in patients with platinum resistant or refractory epithelial ovarian cancer [abstract]. J Clin Oncol. 2008;26:Abstract 3500.
    • Bast R, Lyer R, Hu W, et al. A phase IIa study of a sequential regimen using azacitidine to reverse platinum resistance to carboplatin in patients with platinum resistant or refractory epithelial ovarian cancer [abstract]. J Clin Oncol. 2008;26:Abstract 3500.
  • 42
    • 33750326078 scopus 로고    scopus 로고
    • Phase I study of decitabine-mediated gene expression in patients with cancers involving the lungs, esophagus, or pleura
    • Schrump DS, Fischette MR, Nguyen DM, et al. Phase I study of decitabine-mediated gene expression in patients with cancers involving the lungs, esophagus, or pleura. Clin Cancer Res. 2006;12:5777-5785.
    • (2006) Clin Cancer Res , vol.12 , pp. 5777-5785
    • Schrump, D.S.1    Fischette, M.R.2    Nguyen, D.M.3
  • 43
    • 0032920527 scopus 로고    scopus 로고
    • Prolonged up-regulation of the expression of HLA class I antigens and costimulatory molecules on melanoma cells treated with 5-aza-2′-deoxycytidine (5-AZA-CdR)
    • Coral S, Sigalotti L, Gasparollo A, et al. Prolonged up-regulation of the expression of HLA class I antigens and costimulatory molecules on melanoma cells treated with 5-aza-2′-deoxycytidine (5-AZA-CdR). J Immunother. 1999;22:16-24.
    • (1999) J Immunother , vol.22 , pp. 16-24
    • Coral, S.1    Sigalotti, L.2    Gasparollo, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.