Using DREADDs to isolate internal clocks

Frontiers in Integrative Neuroscience

Volumn , Issue DECEMBER, 2011, Pages

  Farrell, Martilias S ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DESIGNER RECEPTOR EXCLUSIVELY ACTIVATED BY DESIGNER DRUG; DREADD PROTEIN; RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; BEHAVIOR; BRAIN NERVE CELL; CELL SPECIFICITY; CELL SUBPOPULATION; CORPUS STRIATUM; PROTEIN EXPRESSION; STRIATAL MEDIUM SPINY NEURON; TIME PERCEPTION; TRANSGENICS;

EID: 84855290496     PISSN: 16625145     EISSN: None     Source Type: Journal    
DOI: 10.3389/fnint.2011.00087     Document Type: Article

References (27)

1. Agostino, P. V., Golombek, D. A., and Meck, W. H. (2011). Unwinding the molecular basis of interval and circadian timing. Front. Integr. Neurosci. 5:64. doi: 10.3389/fnint.2011.00064
2. Alexander, G. M., Rogan, S. C., Abbas, A. I., Armbruster, B. N., Pei, Y., Allen, J. A., Nonneman, R. J., Hartmann, J., Moy, S. S., Nicolelis, M. A., McNamara, J. O., and Roth, B. L. (2009). Remote control of neuronal activity in transgenic mice expressing evolved G protein-coupled receptors. Neuron 63, 27-39.
3. Allman, M. J., and Meck, W. H. (2011). Pathophysiological distortions in time perception and timed perfor-mance. Brain. doi: 10.1093/brain/awr21
4. Buhusi, C. V., and Meck, W. H. (2005). What makes us tick? Functional and neural mechanisms of interval timing. Nat. Rev. Neurosci. 6, 755-765.
5. Cheng, R. K., Jesuthasan, S., and Penney, T. B. (2011). Time for zebrafish. Front. Integr. Neurosci. 5:40. doi: 10.3389/fnint.2011.00040
6. Coull, J. T., Cheng, R. K., and Meck, W. H. (2011). Neuroanatomical and neurochemical substrates of timing. Neuropsychopharmacology 36, 3-25.
7. Ferguson, S. M., Eskenazi, D., Ishikawa, M., Wanat, M. J., Phillips, P. E., Dong, Y., Roth, B. L., and Neumaier, J. F. (2011). Transient neuronal inhibition reveals oppos-ing roles of indirect and direct pathways in sensitiza-tion. Nat. Neurosci. 14, 22-24.
8. Gibbon, J., Malapani, C., Dale, C. L., and Gallistel, C. (1997). Toward a neurobiology of temporal cogni-tion: advances and challenges. Curr. Opin. Neurobiol.7, 170-184.
9. Gu, B. M., Cheng, R. K., Yin, B., and Meck, W. H. (2011). Quinpirole-induced sensitization to noisy/sparse periodic input: temporal synchronization as a compo-nent of obsessive-compulsive disorder. Neuroscience 179, 143-150.
10. Guettier, J. M., Gautam, D., Scarselli, M., de Azua, I. R., Li, J. H., Rosemond, E., Ma, X., Gonzalez, F. J., Armbruster, B. N., Lu, H., Roth, B. L., and Wess, J. (2009). A chemical-genetic approach to study G pro-tein regulation of beta cell function in vivo. Proc. Natl. Acad. Sci. U.S.A. 106, 19197-19202.
11. Johnson, K. O. (2000). Neural coding. Neuron 26, 563-566.
12. Krashes, M. J., Koda, S., Ye, C., Rogan, S. C., Adams, A. C., Cusher, D. S., Maratos-Flier, E., Roth, B. L., and Lowell, B. B. (2011). Rapid, reversible activation of AgRP neurons drives feeding behavior in mice. J. Clin. Invest. 121, 1424-1428.
13. Matell, M. S., and Meck, W. H. (2004). Cortico-striatal circuits and interval timing: coincidence detection of oscillatory processes. Cogn. Brain Res. 21, 139-170.
14. Matell, M. S., Meck, W. H., and Nicolelis, M. A. L. (2003). Interval timing and the encoding of signal duration by ensembles of cortical and striatal neurons. Behav. Neurosci. 117, 760-773.
15. Meck, W. H. (1996). Neuropharmacology of timing and time perception. Cogn. Brain Res. 3, 227-242.
16. Meck, W. H. (2006a). Frontal cortex lesions eliminate the clock speed effect of dopaminergic drugs on interval timing. Brain Res. 1108, 157-167.
17. Meck, W. H. (2006b). Neuroanatomical localization of an internal clock: a functional link between mesolimbic, nigrostriatal, and mesocortical dopaminergic systems. Brain Res. 1109, 93-107.
18. Meck, W. H., Cheng, R. K., Macdonald, C. J., Gainetdinov, R. R., Caron, M. G., and Cevik, M. O. (2011). Genedose dependent effects of methamphetamine on interval timing in dopamine-transporter knockout mice. Neuropharmacology. doi: 10.1016.j.neuropharm.2011.01.042. [Epub ahead of print].
19. Meck, W. H., Penney, T. B., and Pouthas, V. (2008). Cortico-striatal representation of time in animals and humans. Curr. Opin. Neurobiol. 18, 145-152.
20. Oprisan, S. A., and Buhusi, C. V. (2011). Modeling phar-macological clock and memory patterns of interval timing in a striatal beat-frequency model with realistic, noisy neurons. Front. Integr. Neurosci. 5:52. doi: 10.3389/fnint.2011.00052
21. Pei, Y., Rogan, S. C., Yan, F., and Roth, B. L. (2008). Engineered GPCRs as tools to modulate signal trans-duction. Physiology 23, 313-321.
22. Ray, R. S., Corcoran, A. E., Brust, R. D., Kim, J. C., Richerson, G. B., Nattie, E., and Dymecki, S. M. (2011). Impaired respiratory and body temperature control upon acute serotonergic neuron inhibition. Science 333, 637-642.
23. Sasaki, K., Suzuki, M., Mieda, M., Tsujino, N., Roth, B., and Sakurai, T. (2011). Pharmacogenetic modulation of orexin neurons alters sleep/wakefulness states in mice. PLoS ONE 6, e20360. doi: 10.1371/journal.pone.0020360
24. Sysoeva, O. V., Tonevitsky, A. G., and Wackermann, J. (2010). Genetic determinants of time perception mediated by the serotonergic system. PLoS ONE 5, e12650. doi: 10.1371/journal.pone.0012650
25. Wiener, M., Lohoff, F. W., and Coslett, H. B. (2011). Double dissociation of dopamine genes and timing in humans. J. Cogn. Neurosci. 23, 2811-2821.
26. Wiener, M., Magaro, C. M., and Matell, M. S. (2008). Accurate timing but increased impulsivity follow-ing excitotoxic lesions of the subthalamic nucleus. Neurosci. Lett. 440, 176-180.
27. Yizhar, O., Fenno, L. E., Davidson, T. J., Mogri, M., and Deisseroth, K. (2011). Optogenetics in neural systems. Neuron 71, 9-34.