메뉴 건너뛰기




Volumn 73, Issue 1, 2012, Pages 140-145

Effect of prolonged administration of clenbuterol on airway reactivity and sweating in horses with inflammatory airway disease

Author keywords

[No Author keywords available]

Indexed keywords

ADRENALIN; CLENBUTEROL; HISTAMINE;

EID: 84855275770     PISSN: 00029645     EISSN: None     Source Type: Journal    
DOI: 10.2460/ajvr.73.1.140     Document Type: Article
Times cited : (20)

References (52)
  • 1
    • 84988155794 scopus 로고
    • NAB 365, a beta2-receptor sympathomimetic agent: Clinical experiences in horses with lung disease
    • Sasse HH, Hagejer R. NAB 365, a beta2-receptor sympathomimetic agent: clinical experiences in horses with lung disease. J Vet Pharmacol Ther 1978;1:241-243.
    • (1978) J Vet Pharmacol Ther , vol.1 , pp. 241-243
    • Sasse, H.H.1    Hagejer, R.2
  • 2
    • 0028474719 scopus 로고
    • Clinical efficacy and safety of clenbuterol HCl when administered to effect in horses with chronic obstructive pulmonary disease (COPD)
    • Erichsen DF, Aviad AD, Schultz RH, et al. Clinical efficacy and safety of clenbuterol HCl when administered to effect in horses with chronic obstructive pulmonary disease (COPD). Equine Vet J 1994;26:331-336.
    • (1994) Equine Vet J , vol.26 , pp. 331-336
    • Erichsen, D.F.1    Aviad, A.D.2    Schultz, R.H.3
  • 3
    • 0030603393 scopus 로고    scopus 로고
    • Obstructive pulmonary disease in 18 horses at summer pasture
    • Mair TS. Obstructive pulmonary disease in 18 horses at summer pasture. Vet Rec 1996;138:89-91.
    • (1996) Vet Rec , vol.138 , pp. 89-91
    • Mair, T.S.1
  • 5
    • 0030604852 scopus 로고    scopus 로고
    • Respiratory disease in Thoroughbred horses in training: The relationships between disease and viruses, bacteria and environment
    • Burrell MH, Wood JL, Whitwell KE, et al. Respiratory disease in Thoroughbred horses in training: the relationships between disease and viruses, bacteria and environment. Vet Rec 1996;139:308-313.
    • (1996) Vet Rec , vol.139 , pp. 308-313
    • Burrell, M.H.1    Wood, J.L.2    Whitwell, K.E.3
  • 6
    • 0035956826 scopus 로고    scopus 로고
    • Coughing in Thoroughbred racehorses: Risk factors and tracheal endoscopic and cytological findings
    • Christley RM, Hodgson DR, Rose RJ, et al. Coughing in Thoroughbred racehorses: risk factors and tracheal endoscopic and cytological findings. Vet Rec 2001;148:99-104.
    • (2001) Vet Rec , vol.148 , pp. 99-104
    • Christley, R.M.1    Hodgson, D.R.2    Rose, R.J.3
  • 7
    • 18544388777 scopus 로고    scopus 로고
    • Inflammatory airway disease, nasal discharge and respiratory infections in young British racehorses
    • Wood JL, Newton JR, Chanter N, et al. Inflammatory airway disease, nasal discharge and respiratory infections in young British racehorses. Equine Vet J 2005;37:236-242.
    • (2005) Equine Vet J , vol.37 , pp. 236-242
    • Wood, J.L.1    Newton, J.R.2    Chanter, N.3
  • 8
    • 33751325028 scopus 로고    scopus 로고
    • Recovery from bronchoconstriction and bronchodilator tolerance
    • Haney S, Hancox RJ. Recovery from bronchoconstriction and bronchodilator tolerance. Clin Rev Allergy Immunol 2006;31:181-196.
    • (2006) Clin Rev Allergy Immunol , vol.31 , pp. 181-196
    • Haney, S.1    Hancox, R.J.2
  • 9
    • 33751347563 scopus 로고    scopus 로고
    • Clinical concerns with inhaled beta2-agonists: Adult asthma
    • Cockcroft DW. Clinical concerns with inhaled beta2-agonists: adult asthma. Clin Rev Allergy Immunol 2006;31:197-208.
    • (2006) Clin Rev Allergy Immunol , vol.31 , pp. 197-208
    • Cockcroft, D.W.1
  • 10
    • 0025737495 scopus 로고
    • Adrenergic receptor activity in ponies with recurrent obstructive pulmonary disease
    • Scott JS, Berney CE, Derksen FJ, et al. β-Adrenergic receptor activity in ponies with recurrent obstructive pulmonary disease. Am J Vet Res 1991;52:1416-1422.
    • (1991) Am J Vet Res , vol.52 , pp. 1416-1422
    • Scott, J.S.1    Berney, C.E.2    Derksen, F.J.3
  • 11
    • 56349089917 scopus 로고    scopus 로고
    • Histamine bronchoprovocation does not affect bronchoalveolar lavage fluid cytology, gene expression and protein concentrations of IL-4, IL-8 and IFNgamma
    • Perkins GA, Viel L, Wagner B, et al. Histamine bronchoprovocation does not affect bronchoalveolar lavage fluid cytology, gene expression and protein concentrations of IL-4, IL-8 and IFNgamma. Vet Immunol Immunopathol 2008;126:230-235.
    • (2008) Vet Immunol Immunopathol , vol.126 , pp. 230-235
    • Perkins, G.A.1    Viel, L.2    Wagner, B.3
  • 12
    • 0031990496 scopus 로고    scopus 로고
    • Association between bronchoalveolar lavage cytologic features and airway reactivity in horses with a history of exercise intolerance
    • Hoffman AM, Mazan MR, Ellenberg S. Association between bronchoalveolar lavage cytologic features and airway reactivity in horses with a history of exercise intolerance. Am J Vet Res 1998;59:176-181.
    • (1998) Am J Vet Res , vol.59 , pp. 176-181
    • Hoffman, A.M.1    Mazan, M.R.2    Ellenberg, S.3
  • 13
    • 0032065524 scopus 로고    scopus 로고
    • Pulmonary eosinophilia associated with increased airway responsiveness in young racing horses
    • Hare JE, Viel L. Pulmonary eosinophilia associated with increased airway responsiveness in young racing horses. J Vet Intern Med 1998;12:163-170.
    • (1998) J Vet Intern Med , vol.12 , pp. 163-170
    • Hare, J.E.1    Viel, L.2
  • 14
    • 33645902178 scopus 로고    scopus 로고
    • The anti-inflammatory effects of IV administered clenbuterol in horses with recurrent airway obstruction
    • Laan TT, Bull S, Pirie RS, et al. The anti-inflammatory effects of IV administered clenbuterol in horses with recurrent airway obstruction. Vet J 2006;171:429-437.
    • (2006) Vet J , vol.171 , pp. 429-437
    • Laan, T.T.1    Bull, S.2    Pirie, R.S.3
  • 15
    • 33846838594 scopus 로고    scopus 로고
    • Clenbuterol affects the expression of messenger RNA for interleukin 10 inperipheral leukocytes from horses challenged intrabronchially with lipopolysaccharides
    • van den Hoven R, Duvigneau JC, Hartl RT, et al. Clenbuterol affects the expression of messenger RNA for interleukin 10 inperipheral leukocytes from horses challenged intrabronchially with lipopolysaccharides. Vet Res Commun 2006;30:921-928.
    • (2006) Vet Res Commun , vol.30 , pp. 921-928
    • van den Hoven, R.1    Duvigneau, J.C.2    Hartl, R.T.3
  • 16
    • 0017746446 scopus 로고
    • Identification of the receptor involved in adrenaline mediated sweating in the horse
    • Snow DH. Identification of the receptor involved in adrenaline mediated sweating in the horse. Res Vet Sci 1977;23:246-247.
    • (1977) Res Vet Sci , vol.23 , pp. 246-247
    • Snow, D.H.1
  • 17
    • 70449178337 scopus 로고
    • A histological study of the sweat glands of normal and dry-coated horses
    • Evans CL, Nisbet AM, Ross KA. A histological study of the sweat glands of normal and dry-coated horses. J Comp Pathol 1957;67:397-405.
    • (1957) J Comp Pathol , vol.67 , pp. 397-405
    • Evans, C.L.1    Nisbet, A.M.2    Ross, K.A.3
  • 18
    • 0013891195 scopus 로고
    • Physiological mechanisms that underlie sweating in the horse
    • Evans CL. Physiological mechanisms that underlie sweating in the horse. Br Vet J 1966;122:117-123.
    • (1966) Br Vet J , vol.122 , pp. 117-123
    • Evans, C.L.1
  • 19
    • 0020172967 scopus 로고
    • Summertime plasma catecholamine concentrations in healthy and anhidrotic horses in Louisiana
    • Beadle RE, Norwood GL, Brencick VA. Summertime plasma catecholamine concentrations in healthy and anhidrotic horses in Louisiana. Am J Vet Res 1982;43:1446-1448.
    • (1982) Am J Vet Res , vol.43 , pp. 1446-1448
    • Beadle, R.E.1    Norwood, G.L.2    Brencick, V.A.3
  • 20
    • 2642649367 scopus 로고
    • Action of pilocarpine, arecoline and adrenaline on sweating in the horse
    • Langley JN, Bennett S. Action of pilocarpine, arecoline and adrenaline on sweating in the horse. J Physiol 1923;57:71-72.
    • (1923) J Physiol , vol.57 , pp. 71-72
    • Langley, J.N.1    Bennett, S.2
  • 21
    • 0031909651 scopus 로고    scopus 로고
    • Persistent desensitisation of the beta 2 adrenoceptors expressed by cultured equine sweat gland epithelial cells
    • Rakhit S, Murdoch R, Wilson SM. Persistent desensitisation of the beta 2 adrenoceptors expressed by cultured equine sweat gland epithelial cells. J Exp Biol 1998;201:259-266.
    • (1998) J Exp Biol , vol.201 , pp. 259-266
    • Rakhit, S.1    Murdoch, R.2    Wilson, S.M.3
  • 22
    • 33846030186 scopus 로고    scopus 로고
    • Equine sweating and anhidrosis part 2: Anhidrosis
    • Jenkinson DM, Elder HY, Bovell DL. Equine sweating and anhidrosis part 2: anhidrosis. Vet Dermatol 2007;18:2-11.
    • (2007) Vet Dermatol , vol.18 , pp. 2-11
    • Jenkinson, D.M.1    Elder, H.Y.2    Bovell, D.L.3
  • 23
    • 2442445245 scopus 로고    scopus 로고
    • Pharmacokinetics and disposition of clenbuterol in the horse
    • Soma LR, Uboh CE, Guan F, et al. Pharmacokinetics and disposition of clenbuterol in the horse. J Vet Pharmacol Ther 2004;27:71-77.
    • (2004) J Vet Pharmacol Ther , vol.27 , pp. 71-77
    • Soma, L.R.1    Uboh, C.E.2    Guan, F.3
  • 24
    • 67449085076 scopus 로고    scopus 로고
    • Reproducibility of airway responsiveness in horses using flowmetric plethysmography and histamine bronchoprovocation
    • Nolen-Walston RD, Kuehn H, Boston RD, et al. Reproducibility of airway responsiveness in horses using flowmetric plethysmography and histamine bronchoprovocation. J Vet Intern Med 2009;23:631-635.
    • (2009) J Vet Intern Med , vol.23 , pp. 631-635
    • Nolen-Walston, R.D.1    Kuehn, H.2    Boston, R.D.3
  • 25
    • 0035184511 scopus 로고    scopus 로고
    • Flowmetric comparison of respiratory inductance plethysmography and pneumotachography in horses
    • Hoffman A, Kuehn H, Riedelberger K, et al. Flowmetric comparison of respiratory inductance plethysmography and pneumotachography in horses. J Appl Physiol 2001;91:2767-2775.
    • (2001) J Appl Physiol , vol.91 , pp. 2767-2775
    • Hoffman, A.1    Kuehn, H.2    Riedelberger, K.3
  • 27
    • 0028891033 scopus 로고
    • Effect of clenbuterol on athletic performance
    • Spann C, Winter ME. Effect of clenbuterol on athletic performance. Ann Pharmacother 1995;29:75-77.
    • (1995) Ann Pharmacother , vol.29 , pp. 75-77
    • Spann, C.1    Winter, M.E.2
  • 28
    • 0024542809 scopus 로고
    • Beta-agonists as repartitioning agents: A review
    • Peters AR. Beta-agonists as repartitioning agents: a review. Vet Rec 1989;124:417-420.
    • (1989) Vet Rec , vol.124 , pp. 417-420
    • Peters, A.R.1
  • 29
    • 33144475944 scopus 로고    scopus 로고
    • Changes in adiponectin, leptin, and fat mass after clenbuterol treatment in horses
    • Kearns CF, McKeever KH, Malinowski K. Changes in adiponectin, leptin, and fat mass after clenbuterol treatment in horses. Med Sci Sports Exerc 2006;38:262-267.
    • (2006) Med Sci Sports Exerc , vol.38 , pp. 262-267
    • Kearns, C.F.1    McKeever, K.H.2    Malinowski, K.3
  • 30
    • 0034750183 scopus 로고    scopus 로고
    • Chronic administration of therapeutic levels of clenbuterol acts as a repartitioning agent
    • Kearns CF, McKeever KH, Malinowski K, et al. Chronic administration of therapeutic levels of clenbuterol acts as a repartitioning agent. J Appl Physiol 2001;91:2064-2070.
    • (2001) J Appl Physiol , vol.91 , pp. 2064-2070
    • Kearns, C.F.1    McKeever, K.H.2    Malinowski, K.3
  • 31
    • 0036118015 scopus 로고    scopus 로고
    • Chronic clenbuterol administration negatively alters cardiac function
    • Sleeper MM, Kearns CF, McKeever KH. Chronic clenbuterol administration negatively alters cardiac function. Med Sci Sports Exerc 2002;34:643-650.
    • (2002) Med Sci Sports Exerc , vol.34 , pp. 643-650
    • Sleeper, M.M.1    Kearns, C.F.2    McKeever, K.H.3
  • 32
    • 0036897813 scopus 로고    scopus 로고
    • Clenbuterol diminishes aerobic performance in horses
    • Kearns CF, McKeever KH. Clenbuterol diminishes aerobic performance in horses. Med Sci Sports Exerc 2002;34:1976-1985.
    • (2002) Med Sci Sports Exerc , vol.34 , pp. 1976-1985
    • Kearns, C.F.1    McKeever, K.H.2
  • 33
    • 0027442367 scopus 로고
    • Differential down-regulation of pulmonary beta 1-and beta 2-adrenoceptor messenger RNA with prolonged in vivo infusion of isoprenaline
    • Nishikawa M, Mak JC, Shirasaki H, et al. Differential down-regulation of pulmonary beta 1-and beta 2-adrenoceptor messenger RNA with prolonged in vivo infusion of isoprenaline. Eur J Pharmacol 1993;247:131-138.
    • (1993) Eur J Pharmacol , vol.247 , pp. 131-138
    • Nishikawa, M.1    Mak, J.C.2    Shirasaki, H.3
  • 34
    • 0029884416 scopus 로고    scopus 로고
    • Identification of the G protein-coupled receptor kinase phosphorylation sites in the human beta2-adrenergic receptor
    • Fredericks ZL, Pitcher JA, Lefkowitz RJ. Identification of the G protein-coupled receptor kinase phosphorylation sites in the human beta2-adrenergic receptor. J Biol Chem 1996;271:13796-13803.
    • (1996) J Biol Chem , vol.271 , pp. 13796-13803
    • Fredericks, Z.L.1    Pitcher, J.A.2    Lefkowitz, R.J.3
  • 35
    • 0025352299 scopus 로고
    • Beta-arrestin: A protein that regulates beta-adrenergic receptor function
    • Lohse MJ, Benovic JL, Codina J, et al. Beta-arrestin: a protein that regulates beta-adrenergic receptor function. Science 1990;248:1547-1550.
    • (1990) Science , vol.248 , pp. 1547-1550
    • Lohse, M.J.1    Benovic, J.L.2    Codina, J.3
  • 36
    • 0037210650 scopus 로고    scopus 로고
    • Dexamethasoneinduced increase in lymphocyte beta-adrenergic receptor density and cAMP formation in vivo
    • Abraham G, Schusser GF, Ungemach FR. Dexamethasoneinduced increase in lymphocyte beta-adrenergic receptor density and cAMP formation in vivo. Pharmacology 2003;67:1-5.
    • (2003) Pharmacology , vol.67 , pp. 1-5
    • Abraham, G.1    Schusser, G.F.2    Ungemach, F.R.3
  • 37
    • 0043263994 scopus 로고    scopus 로고
    • Pharmacological and biochemical characterization of the beta-adrenergic signal transduction pathway in different segments of the respiratory tract
    • Abraham G, Kottke C, Dhein S, et al. Pharmacological and biochemical characterization of the beta-adrenergic signal transduction pathway in different segments of the respiratory tract. Biochem Pharmacol 2003;66:1067-1081.
    • (2003) Biochem Pharmacol , vol.66 , pp. 1067-1081
    • Abraham, G.1    Kottke, C.2    Dhein, S.3
  • 38
    • 0027490144 scopus 로고
    • Regular inhaled salbutamol and airway responsiveness to allergen
    • Cockcroft DW, McParland CP, Britto SA, et al. Regular inhaled salbutamol and airway responsiveness to allergen. Lancet 1993;342:833-837.
    • (1993) Lancet , vol.342 , pp. 833-837
    • Cockcroft, D.W.1    McParland, C.P.2    Britto, S.A.3
  • 39
    • 0026786753 scopus 로고
    • Long-term effects of a long-acting beta 2-adrenoceptor agonist, salmeterol, on airway hyperresponsiveness in patients with mild asthma
    • Cheung D, Timmers MC, Zwinderman AH, et al. Long-term effects of a long-acting beta 2-adrenoceptor agonist, salmeterol, on airway hyperresponsiveness in patients with mild asthma. N Engl J Med 1992;327:1198-1203.
    • (1992) N Engl J Med , vol.327 , pp. 1198-1203
    • Cheung, D.1    Timmers, M.C.2    Zwinderman, A.H.3
  • 40
    • 0029145693 scopus 로고
    • Regular formoterol treatment in mild asthma. Effect on bronchial responsiveness during and after treatment
    • Yates DH, Sussman HS, Shaw MJ, et al. Regular formoterol treatment in mild asthma. Effect on bronchial responsiveness during and after treatment. Am J Respir Crit Care Med 1995;152:1170-1174.
    • (1995) Am J Respir Crit Care Med , vol.152 , pp. 1170-1174
    • Yates, D.H.1    Sussman, H.S.2    Shaw, M.J.3
  • 41
    • 0030042988 scopus 로고    scopus 로고
    • The effect of regular inhaled albuterol on exercise-induced bronchoconstriction
    • Inman MD, O'Byrne PM. The effect of regular inhaled albuterol on exercise-induced bronchoconstriction. Am J Respir Crit Care Med 1996;153:65-69.
    • (1996) Am J Respir Crit Care Med , vol.153 , pp. 65-69
    • Inman, M.D.1    O'Byrne, P.M.2
  • 42
    • 0035113199 scopus 로고    scopus 로고
    • Regular inhaled salbutamol: Effect on airway responsiveness to methacholine and adenosine 5′-monophosphate and tolerance to bronchoprotection
    • Jokic R, Swystun VA, Davis BE, et al. Regular inhaled salbutamol: effect on airway responsiveness to methacholine and adenosine 5′-monophosphate and tolerance to bronchoprotection. Chest 2001;119:370-375.
    • (2001) Chest , vol.119 , pp. 370-375
    • Jokic, R.1    Swystun, V.A.2    Davis, B.E.3
  • 43
    • 0023112091 scopus 로고
    • Effect of clenbuterol on histamine-induced airway obstruction in ponies
    • Derksen FJ, Scott JS, Slocombe RF, et al. Effect of clenbuterol on histamine-induced airway obstruction in ponies. Am J Vet Res 1987;48:423-426.
    • (1987) Am J Vet Res , vol.48 , pp. 423-426
    • Derksen, F.J.1    Scott, J.S.2    Slocombe, R.F.3
  • 44
    • 51349148013 scopus 로고    scopus 로고
    • Guidelines for asthma management: A review and comparison of 5 current guidelines
    • Myers TR. Guidelines for asthma management: a review and comparison of 5 current guidelines. Respir Care 2008;53:751-767.
    • (2008) Respir Care , vol.53 , pp. 751-767
    • Myers, T.R.1
  • 45
    • 69249222635 scopus 로고    scopus 로고
    • Inhaled corticosteroids as combination therapy with beta-adrenergic agonists in airways disease: Present and future
    • Chung KF, Caramori G, Adcock IM. Inhaled corticosteroids as combination therapy with beta-adrenergic agonists in airways disease: present and future. Eur J Clin Pharmacol 2009;65:853-871.
    • (2009) Eur J Clin Pharmacol , vol.65 , pp. 853-871
    • Chung, K.F.1    Caramori, G.2    Adcock, I.M.3
  • 46
    • 0036716214 scopus 로고    scopus 로고
    • Regulation of equine lymphocyte beta-adrenoceptors under the influence of clenbuterol and dexamethasone
    • Abraham G, Brodde OE, Ungemach FR. Regulation of equine lymphocyte beta-adrenoceptors under the influence of clenbuterol and dexamethasone. Equine Vet J 2002;34:587-593.
    • (2002) Equine Vet J , vol.34 , pp. 587-593
    • Abraham, G.1    Brodde, O.E.2    Ungemach, F.R.3
  • 47
    • 0026667741 scopus 로고
    • Effects of xylazine on airway function in ponies with recurrent airway obstruction
    • Broadstone RV, Gray PR, Robinson NE, et al. Effects of xylazine on airway function in ponies with recurrent airway obstruction. Am J Vet Res 1992;53:1813-1817.
    • (1992) Am J Vet Res , vol.53 , pp. 1813-1817
    • Broadstone, R.V.1    Gray, P.R.2    Robinson, N.E.3
  • 48
    • 0021348048 scopus 로고
    • Predominantly beta-adrenergic control of equine sweating
    • Bijman J, Quinton PM. Predominantly beta-adrenergic control of equine sweating. Am J Physiol 1984;246:R349-R353.
    • (1984) Am J Physiol , vol.246
    • Bijman, J.1    Quinton, P.M.2
  • 49
    • 0027674151 scopus 로고
    • Investigation of stimulussecretion coupling in equine sweat gland epithelia using cell culture techniques
    • Wilson SM, Pediani JD, Ko WH, et al. Investigation of stimulussecretion coupling in equine sweat gland epithelia using cell culture techniques. J Exp Biol 1993;183:279-299.
    • (1993) J Exp Biol , vol.183 , pp. 279-299
    • Wilson, S.M.1    Pediani, J.D.2    Ko, W.H.3
  • 50
    • 0020803437 scopus 로고
    • Composition of sweat of the horse during prolonged epinephrine (adrenaline) infusion, heat exposure, and exercise
    • Kerr MG, Snow DH. Composition of sweat of the horse during prolonged epinephrine (adrenaline) infusion, heat exposure, and exercise. Am J Vet Res 1983;44:1571-1577.
    • (1983) Am J Vet Res , vol.44 , pp. 1571-1577
    • Kerr, M.G.1    Snow, D.H.2
  • 51
  • 52
    • 47049100680 scopus 로고    scopus 로고
    • Quantitative intradermal terbutaline sweat test in horses
    • MacKay RJ. Quantitative intradermal terbutaline sweat test in horses. Equine Vet J 2008;40:518-520.
    • (2008) Equine Vet J , vol.40 , pp. 518-520
    • Mackay, R.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.