High-throughput screening for various classes of doping agents using a new 'dilute-and-shoot' liquid chromatography-tandem mass spectrometry multi-target approach

Drug Testing and Analysis

Volumn 3, Issue 11-12, 2011, Pages 836-850

  Guddat, S ^a   Solymos, E ^b   Orlovius, A ^a,c   Thomas, A ^a   Sigmund, G ^a   Geyer, H ^a   Thevis, M ^a   Schanzer W ^a  

^a GERMAN SPORT UNIVERSITY COLOGNE   (Germany)

^b EÖTVÖS LORÁND UNIVERSITY   (Hungary)

^c UNIVERSITY OF BONN   (Germany)

Author keywords

DEHP glucuronides; Dilute and shoot; High throughput screening; LC MS MS; Plasma volume expanders; Sports drug testing

Indexed keywords

BIOMOLECULES; CONTROLLED DRUG DELIVERY; DEXTRAN; DIRECT INJECTION; DRUG PRODUCTS; ELECTROSPRAY IONIZATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; SCREENING; SOLVENTS; SPORTS; STARCH; THROUGHPUT;

DI(2-ETHYLHEXYL)PHTHALATE; DI(2-ETHYLHEXYL)PHTHALATE GLUCURONIDE; DILUTE-AND-SHOOT; DRUG TESTING; GLUCURONIDES; HIGH THROUGHPUT SCREENING; LC-MS-MS; LC.MS/MS; PLASMA VOLUME; PLASMA VOLUME EXPANDER; SPORT DRUG TESTING;

METABOLITES;

5 AMINO 4 IMIDAZOLECARBOXAMIDE RIBOSIDE; ANDARINE; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; CENTRAL STIMULANT AGENT; DEXTRAN; DIURETIC AGENT; HETASTARCH; NARCOTIC AGENT; PHTHALIC ACID BIS(2 ETHYLHEXYL) ESTER; PLASMA SUBSTITUTE; SELECTIVE ANDROGEN RECEPTOR MODULATOR; UNCLASSIFIED DRUG; URICOSURIC AGENT;

ACCURACY; ARTICLE; BLOOD TRANSFUSION; CONTROLLED STUDY; DOPING; DRUG SCREENING; HIGH THROUGHPUT SCREENING; HUMAN; LIQUID CHROMATOGRAPHY; PRIORITY JOURNAL; QUALITATIVE ANALYSIS; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY; URINALYSIS;

EID: 84855237947     PISSN: 19427603     EISSN: 19427611     Source Type: Journal    
DOI: 10.1002/dta.372     Document Type: Article

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