Bone marrow-derived monocyte lineage cells recruited by MIP-1β promote physiological revascularization in mouse model of oxygen-induced retinopathy

Laboratory Investigation

Volumn 92, Issue 1, 2012, Pages 91-101

  Ishikawa, Keijiro ^a   Yoshida, Shigeo ^a   Nakao, Shintaro ^a   Sassa, Yukio ^a   Asato, Ryo ^a   Kohno, Riichiro ^a   Arima, Mitsuru ^a   Kita, Takeshi ^a   Yoshida, Ayako ^a   Ohuchida, Kenoki ^a   Ishibashi, Tatsuro ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

angiogenesis; chemokines; inflammation; ischemic retinopathy; macrophage microglia

Indexed keywords

CHEMOKINE RECEPTOR CCR5; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; NEUTRALIZING ANTIBODY; OXYGEN; VASCULOTROPIN A; VASCULOTROPIN ANTIBODY;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW CELL; C57BL 6 MOUSE; CELL INFILTRATION; CELL LINEAGE; CONTROLLED STUDY; HYPOXIA; MONOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; RETINA; RETINA NEOVASCULARIZATION; RETINOPATHY; UPREGULATION;

ANIMALS; BONE MARROW CELLS; CELL LINEAGE; CELL MOVEMENT; CHEMOKINE CCL4; DISEASE MODELS, ANIMAL; MICE; MICE, INBRED C57BL; MONOCYTES; OXYGEN; RECEPTORS, CCR5; RETINA; RETINAL DISEASES; RETINAL NEOVASCULARIZATION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84855235596     PISSN: 00236837     EISSN: 15300307     Source Type: Journal    
DOI: 10.1038/labinvest.2011.141     Document Type: Article

References (39)

1. Ishikawa K, Yoshida S, Kadota K, et al. Gene expression profile of hyperoxic and hypoxic retinas in a mouse model of oxygen-induced retinopathy. Invest Ophthalmol Vis Sci 2010;51:4307-4319.
2. Schall TJ, Bacon KB. Chemokines, leukocyte trafficking, and inflammation. Curr Opin Immunol 1994;6:865-873.
3. Wolpe SD, Davatelis G, Sherry B, et al. Macrophages secrete a novel heparin-binding protein with inflammatory and neutrophil chemokinetic properties. J Exp Med 1988;167:570-581. (Pubitemid 18073655)
4. Koch AE, Kunkel SL, Shah MR, et al. Macrophage inflammatory protein- 1 beta: a C-C chemokine in osteoarthritis. Clin Immunol Immunopathol 1995;77:307-314.
5. O'Grady NP, Tropea M, Preas II HL, et al. Detection of macrophage inflammatory protein (MIP)-1alpha and MIP-1beta during experimental endotoxemia and human sepsis. J Infect Dis 1999;179:136-141. (Pubitemid 29028348)
6. Hasegawa M, Sato S, Takehara K. Augmented production of chemokines (monocyte chemotactic protein-1 (MCP-1), macrophage inflammatory protein-1alpha (MIP-1alpha) and MIP-1beta) in patients with systemic sclerosis: MCP-1 and MIP-1alpha may be involved in the development of pulmonary fibrosis. Clin Exp Immunol 1999;117:159-165. (Pubitemid 29292792)
7. Jo N, Wu GS, Rao NA. Upregulation of chemokine expression in the retinal vasculature in ischemia-reperfusion injury. Invest Ophthalmol Vis Sci 2003;44:4054-4060. (Pubitemid 37047982)
8. Ambati BK, Anand A, Joussen AM, et al. Sustained inhibition of corneal neovascularization by genetic ablation of CCR5. Invest Ophthalmol Vis Sci 2003;44:590-593. (Pubitemid 36159703)
9. Aiello LP, Avery RL, Arrigg PG, et al. Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders. N Engl J Med 1994;331:1480-1487. (Pubitemid 24356306)
10. Gragoudas ES, Adamis AP, Cunningham Jr ET, et al. Pegaptanib for neovascular age-related macular degeneration. N Engl J Med 2004;351:2805-2816. (Pubitemid 40051904)
11. Shimura M, Yasuda K. Macular ischaemia after intravitreal bevacizumab injection in patients with central retinal vein occlusion and a history of diabetes and vascular disease. Br J Ophthalmol 2010;94:381-383.
12. Saint-Geniez M, Maharaj AS, Walshe TE, et al. Endogenous VEGF is required for visual function: evidence for a survival role on muller cells and photoreceptors. PLoS One 2008;3:e3554.
13. Polverini PJ, Cotran PS, Gimbrone Jr MA, et al. Activated macrophages induce vascular proliferation. Nature 1977;269:804-806. (Pubitemid 8208827)
14. Ishida S, Usui T, Yamashiro K, et al. VEGF164-mediated inflammation is required for pathological, but not physiological, ischemia-induced retinal neovascularization. J Exp Med 2003;198:483-489. (Pubitemid 36976059)
15. Lima e Silva R, Shen J, Hackett SF, et All rights reserved. The SDF-1/CXCR4 ligand/ receptor pair is an important contributor to several types of ocular neovascularization. FASEB J 2007 21: 3219-3230. (Pubitemid 47565540)
16. Ritter MR, Banin E, Moreno SK, et al. Myeloid progenitors differentiate into microglia and promote vascular repair in a model of ischemic retinopathy. J Clin Invest 2006;116:3266-3276. (Pubitemid 44878641)
17. Smith LE, Wesolowski E, McLellan A, et al. Oxygen-induced retinopathy in the mouse. Invest Ophthalmol Vis Sci 1994;35:101-111. (Pubitemid 24046832)
18. Tachikawa T, Irie T. A new molecular biology approach in morphology: basic method and application of laser microdissection. Med Electron Microsc 2004;37:82-88. (Pubitemid 38980908)
19. Yoshida S, Yoshida A, Ishibashi T, et al. Role of MCP-1 and MIP-1alpha in retinal neovascularization during postischemic inflammation in a mouse model of retinal neovascularization. J Leukoc Biol 2003;73:137-144. (Pubitemid 36125684)
20. Yoshida S, Ogura A, Ishikawa K, et al. Gene expression profile of fibrovascular membranes from patients with proliferative diabetic retinopathy. Br J Ophthalmol 2009;94:795-801.
21. Connor KM, Krah NM, Dennison RJ, et al. Quantification of oxygeninduced retinopathy in the mouse: a model of vessel loss, vessel regrowth and pathological angiogenesis. Nat Protoc 2009;4: 1565-1573.
22. Pierce EA, Avery RL, Foley ED, et al. Vascular endothelial growth factor/ vascular permeability factor expression in a mouse model of retinal neovascularization. Proc Natl Acad Sci USA 1995;92:905-909.
23. Soulet D, Rivest S. Bone-marrow-derived microglia: myth or reality? Curr Opin Pharmacol 2008;8:508-518.
24. Sata M, Saiura A, Kunisato A, et al. Hematopoietic stem cells differentiate into vascular cells that participate in the pathogenesis of atherosclerosis. Nat Med 2002;8:403-409. (Pubitemid 34407037)
25. Rajantie I, Ilmonen M, Alminaite A, et al. Adult bone marrow-derived cells recruited during angiogenesis comprise precursors for periendothelial vascular mural cells. Blood 2004;104:2084-2086. (Pubitemid 39297861)
26. Mabuchi T, Kitagawa K, Ohtsuki T, et al. Contribution of microglia/ macrophages to expansion of infarction and response of oligodendrocytes after focal cerebral ischemia in rats. Stroke 2000;31:1735-1743. (Pubitemid 30437531)
27. Buttini M, Appel K, Sauter A, et al. Expression of tumor necrosis factor alpha after focal cerebral ischaemia in the rat. Neuroscience 1996;71: 1-16. (Pubitemid 26041886)
28. Elkabes S, DiCicco-Bloom EM, Black IB. Brain microglia/macrophages express neurotrophins that selectively regulate microglial proliferation and function. J Neurosci 1996;16:2508-2521. (Pubitemid 26122673)
29. Lange C, Ehlken C, Stahl A, et al. Kinetics of retinal vaso-obliteration and neovascularisation in the oxygen-induced retinopathy (OIR) mouse model. Graefes Arch Clin Exp Ophthalmol 2009;247:1205-1211.
30. Ozaki H, Yu AY, Della N, et al. Hypoxia inducible factor-1alpha is increased in ischemic retina: temporal and spatial correlation with VEGF expression. Invest Ophthalmol Vis Sci 1999;40:182-189. (Pubitemid 29029587)
31. Davies MH, Eubanks JP, Powers MR. Microglia and macrophages are increased in response to ischemia-induced retinopathy in the mouse retina. Mol Vis 2006;12:467-477.
32. Stahl A, Connor KM, Sapieha P, et al. The mouse retina as an angiogenesis model. Invest Ophthalmol Vis Sci 2010;51:2813-2826.
33. Bosco MC, Reffo G, Puppo M, et al. Hypoxia inhibits the expression of the CCR5 chemokine receptor in macrophages. Cell Immunol 2004;228:1-7. (Pubitemid 38760116)
34. Uguccioni M, D'Apuzzo M, Loetscher M, et al. Actions of the chemotactic cytokines MCP-1, MCP-2, MCP-3, RANTES, MIP-1 alpha and MIP-1 beta on human monocytes. Eur J Immunol 1995; 25:64-68.
35. Davies MH, Stempel AJ, Powers MR. MCP-1 deficiency delays regression of pathologic retinal neovascularization in a model of ischemic retinopathy. Invest Ophthalmol Vis Sci 2008;49:4195-4202.
36. Bosco MC, Puppo M, Blengio F, et al. Monocytes and dendritic cells in a hypoxic environment: spotlights on chemotaxis and migration. Immunobiology 2008;213:733-749.
37. Zou H, Otani A, Oishi A, et al. Bone marrow-derived cells are differentially involved in pathological and physiological retinal angiogenesis in mice. Biochem Biophys Res Commun 2010;391: 1268-1273.
38. Penn JS, Tolman BL, Henry MM. Oxygen-induced retinopathy in the rat: relationship of retinal nonperfusion to subsequent neovascularization. Invest Ophthalmol Vis Sci 1994;35:3429-3435. (Pubitemid 24337949)
39. Aiello LP, Pierce EA, Foley ED, et al. Suppression of retinal neovascularization in vivo by inhibition of vascular endothelial growth factor (VEGF) using soluble VEGF-receptor chimeric proteins. Proc Natl Acad Sci USA 1995;92:10457-10461.