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Volumn 28, Issue 2, 2012, Pages 118-123

Saturated fat and cardiovascular disease: The discrepancy between the scientific literature and dietary advice

Author keywords

Coronary heart disease; Dietary guidelines; European Food Safety Authority; Institute of Medicine; Stroke; U.S. Department of Agriculture

Indexed keywords

HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MONOUNSATURATED FATTY ACID; POLYUNSATURATED FATTY ACID; SATURATED FATTY ACID;

EID: 84855215993     PISSN: 08999007     EISSN: 18731244     Source Type: Journal    
DOI: 10.1016/j.nut.2011.08.017     Document Type: Review
Times cited : (80)

References (41)
  • 1
    • 0038135048 scopus 로고    scopus 로고
    • Effects of dietary fatty acids and carbohydrates on the ratio of serum total to HDL cholesterol and on serum lipids and apolipoproteins: a meta-analysis of 60 controlled trials
    • Mensink R.P., Zock P.L., Kester A.D., Katan M.B. Effects of dietary fatty acids and carbohydrates on the ratio of serum total to HDL cholesterol and on serum lipids and apolipoproteins: a meta-analysis of 60 controlled trials. Am J Clin Nutr 2003, 77:1146-1155.
    • (2003) Am J Clin Nutr , vol.77 , pp. 1146-1155
    • Mensink, R.P.1    Zock, P.L.2    Kester, A.D.3    Katan, M.B.4
  • 2
    • 36549034768 scopus 로고    scopus 로고
    • Blood cholesterol and vascular mortality byage, sex, and blood pressure: a meta-analysis of individual data from61 prospective studies with 55,000 vascular deaths
    • Prospective Studies Collaboration
    • Blood cholesterol and vascular mortality byage, sex, and blood pressure: a meta-analysis of individual data from61 prospective studies with 55,000 vascular deaths. Lancet 2007, 370:1829-1839. Prospective Studies Collaboration.
    • (2007) Lancet , vol.370 , pp. 1829-1839
  • 3
    • 84855219938 scopus 로고    scopus 로고
    • USDA and UDHHS. Report of the Dietary Guidelines Advisory Committee on the dietary guidelines for Americans, 2010. June 15, 2010. Available at: Accessed February 13
    • USDA and UDHHS. Report of the Dietary Guidelines Advisory Committee on the dietary guidelines for Americans, 2010. June 15, 2010. Available at: Accessed February 13, 2011. http://www.cnpp.usda.gov/DGAs2010-DGACReport.htm.
    • (2011)
  • 4
    • 77957286945 scopus 로고    scopus 로고
    • In the face of contradictory evidence: report of the Dietary Guidelines for Americans Committee
    • Hite A.H., Feinman R.D., Guzman G.E., Satin M., Schoenfeld P.A., Wood R.J. In the face of contradictory evidence: report of the Dietary Guidelines for Americans Committee. Nutrition 2010, 26:915-924.
    • (2010) Nutrition , vol.26 , pp. 915-924
    • Hite, A.H.1    Feinman, R.D.2    Guzman, G.E.3    Satin, M.4    Schoenfeld, P.A.5    Wood, R.J.6
  • 5
    • 84855228843 scopus 로고    scopus 로고
    • Institute of Medicine. Dietary fats: total fat and fatty acids. In: Dietary reference intakes for energy, carbohydrate, fiber, fat, fatty acids, cholesterol, protein, and amino acids (macronutrients); 2005. Available at: Accessed February 14
    • Institute of Medicine. Dietary fats: total fat and fatty acids. In: Dietary reference intakes for energy, carbohydrate, fiber, fat, fatty acids, cholesterol, protein, and amino acids (macronutrients); 2005. Available at: Accessed February 14, 2011. http://books.nap.edu/openbook.php?record_id=10490%26page=422.
    • (2011)
  • 6
    • 77954879552 scopus 로고    scopus 로고
    • Scientific opinion on dietary reference values for fats, including saturated fatty acids, polyunsaturated fatty acids, monounsaturated fatty acids, trans fatty acids, and cholesterol
    • EFSA Panel on Dietetic Products, Nutrition, and Allergies (NDA), Available at, Accessed February 14, 2011
    • Scientific opinion on dietary reference values for fats, including saturated fatty acids, polyunsaturated fatty acids, monounsaturated fatty acids, trans fatty acids, and cholesterol. EFSA J 2010, 8:1461. EFSA Panel on Dietetic Products, Nutrition, and Allergies (NDA), Available at, Accessed February 14, 2011. http://www.efsa.europa.eu/en/efsajournal/doc/1461.pdf.
    • (2010) EFSA J , vol.8 , pp. 1461
  • 7
    • 0026740415 scopus 로고
    • Effect of dietary fatty acids on serum lipids and lipoproteins. A meta-analysis of 27 trials
    • Mensink R.P., Katan M.B. Effect of dietary fatty acids on serum lipids and lipoproteins. A meta-analysis of 27 trials. Arterioscler Thromb 1992, 12:911-919.
    • (1992) Arterioscler Thromb , vol.12 , pp. 911-919
    • Mensink, R.P.1    Katan, M.B.2
  • 8
    • 36849009600 scopus 로고    scopus 로고
    • Comparison of monounsaturated fat with carbohydrates as a replacement for saturated fat in subjects with a high metabolic risk profile: studies in the fasting and postprandial states
    • Berglund L., Lefevre M., Ginsberg H.N., Kris-Etherton P.M., Elmer P.J., Stewart P.W., et al. Comparison of monounsaturated fat with carbohydrates as a replacement for saturated fat in subjects with a high metabolic risk profile: studies in the fasting and postprandial states. Am J Clin Nutr 2007, 86:1611-1620.
    • (2007) Am J Clin Nutr , vol.86 , pp. 1611-1620
    • Berglund, L.1    Lefevre, M.2    Ginsberg, H.N.3    Kris-Etherton, P.M.4    Elmer, P.J.5    Stewart, P.W.6
  • 9
  • 10
    • 0014882147 scopus 로고
    • The Oslo Diet-Heart Study. Eleven-year report
    • Leren P. The Oslo Diet-Heart Study. Eleven-year report. Circulation 1970, 42:935-942.
    • (1970) Circulation , vol.42 , pp. 935-942
    • Leren, P.1
  • 11
    • 0037203476 scopus 로고    scopus 로고
    • Randomized clinical trials on the effects of dietary fat and carbohydrate on plasma lipoproteins and cardiovascular disease
    • Sacks F.M., Katan M. Randomized clinical trials on the effects of dietary fat and carbohydrate on plasma lipoproteins and cardiovascular disease. Am J Med 2002, 113(suppl 9B):13S-24S.
    • (2002) Am J Med , vol.113 , Issue.SUPPL. 9B
    • Sacks, F.M.1    Katan, M.2
  • 12
    • 0001910476 scopus 로고
    • A controlled clinical trial of a diet high in unsaturated fat in preventing complications of atherosclerosis
    • Dayton S., Pearce M.L., Hashimoto S., Dixon W.J., Tomiyasu U. A controlled clinical trial of a diet high in unsaturated fat in preventing complications of atherosclerosis. Circulation 1969, 40(suppl 2):1-63.
    • (1969) Circulation , vol.40 , Issue.SUPPL. 2 , pp. 1-63
    • Dayton, S.1    Pearce, M.L.2    Hashimoto, S.3    Dixon, W.J.4    Tomiyasu, U.5
  • 13
    • 0014433318 scopus 로고
    • Controlled trial of soya-bean oil in myocardial infarction
    • Research Committee
    • Controlled trial of soya-bean oil in myocardial infarction. Lancet 1968, 2:693-699. Research Committee.
    • (1968) Lancet , vol.2 , pp. 693-699
  • 15
    • 70349269869 scopus 로고    scopus 로고
    • Dietary fat and coronary heart disease: summary of evidence from prospective cohort and randomised controlled trials
    • Skeaff C.M., Miller J. Dietary fat and coronary heart disease: summary of evidence from prospective cohort and randomised controlled trials. Ann Nutr Metab 2009, 55:173-201.
    • (2009) Ann Nutr Metab , vol.55 , pp. 173-201
    • Skeaff, C.M.1    Miller, J.2
  • 16
    • 65249102362 scopus 로고    scopus 로고
    • A systematic review of the evidence supporting a causal link between dietary factors and coronary heart disease
    • Mente A. A systematic review of the evidence supporting a causal link between dietary factors and coronary heart disease. Arch Intern Med 2009, 169:659-669.
    • (2009) Arch Intern Med , vol.169 , pp. 659-669
    • Mente, A.1
  • 17
    • 77749292085 scopus 로고    scopus 로고
    • Meta-analysis of prospective cohort studies evaluating the association of saturated fat with cardiovascular disease
    • Siri-Tarino P.W., Sun Q., Hu F.B., Krauss R.M. Meta-analysis of prospective cohort studies evaluating the association of saturated fat with cardiovascular disease. Am J Clin Nutr 2010, 91:535-546.
    • (2010) Am J Clin Nutr , vol.91 , pp. 535-546
    • Siri-Tarino, P.W.1    Sun, Q.2    Hu, F.B.3    Krauss, R.M.4
  • 20
    • 0021345128 scopus 로고
    • Diet, prevalence and 10-year mortality from coronary heart disease in 871 middle-aged men. The Zutphen Study
    • Kromhout D., de Lezenne Coulander C. Diet, prevalence and 10-year mortality from coronary heart disease in 871 middle-aged men. The Zutphen Study. Am J Epidemiol 1984, 119:733-741.
    • (1984) Am J Epidemiol , vol.119 , pp. 733-741
    • Kromhout, D.1    de Lezenne Coulander, C.2
  • 21
    • 0029069165 scopus 로고
    • The protective effect of a small amount of fish on coronary heart disease mortality in an elderly population
    • Kromhout D., Feskens E.J., Bowles C.H. The protective effect of a small amount of fish on coronary heart disease mortality in an elderly population. Int J Epidemiol 1995, 24:340-345.
    • (1995) Int J Epidemiol , vol.24 , pp. 340-345
    • Kromhout, D.1    Feskens, E.J.2    Bowles, C.H.3
  • 22
    • 0043169427 scopus 로고    scopus 로고
    • Dietary fat predicts coronary heart disease events in subjects with type 2 diabetes
    • Soinio M., Laakso M., Lehto S., Hakala P., Rönnemaa T. Dietary fat predicts coronary heart disease events in subjects with type 2 diabetes. Diabetes Care 2003, 26:619-624.
    • (2003) Diabetes Care , vol.26 , pp. 619-624
    • Soinio, M.1    Laakso, M.2    Lehto, S.3    Hakala, P.4    Rönnemaa, T.5
  • 23
    • 0037831001 scopus 로고    scopus 로고
    • N-3 Fatty acids and 5-y risks of death and cardiovascular disease events in patients with coronary artery disease
    • Erkkilä A.T., Lehto S., Pyörälä K., Uusitupa M.I. n-3 Fatty acids and 5-y risks of death and cardiovascular disease events in patients with coronary artery disease. Am J Clin Nutr 2003, 78:65-71.
    • (2003) Am J Clin Nutr , vol.78 , pp. 65-71
    • Erkkilä, A.T.1    Lehto, S.2    Pyörälä, K.3    Uusitupa, M.I.4
  • 24
    • 21044434630 scopus 로고    scopus 로고
    • Diet in childhood and adult cardiovascular and all cause mortality: the Boyd Orr cohort
    • Ness A.R., Maynard M., Frankel S., Smith G.D., Frobisher C., Leary S.D. Diet in childhood and adult cardiovascular and all cause mortality: the Boyd Orr cohort. Heart 2005, 91:894-898.
    • (2005) Heart , vol.91 , pp. 894-898
    • Ness, A.R.1    Maynard, M.2    Frankel, S.3    Smith, G.D.4    Frobisher, C.5    Leary, S.D.6
  • 25
    • 52449090229 scopus 로고    scopus 로고
    • Dietary calcium intake and risks of stroke, its subtypes, and coronary heart disease in Japanese: the JPHC Study Cohort I
    • Umesawa M., Iso H., Ishihara J., Saito I., Kokubo Y., Inoue M. Dietary calcium intake and risks of stroke, its subtypes, and coronary heart disease in Japanese: the JPHC Study Cohort I. Stroke 2008, 39:2449-2456.
    • (2008) Stroke , vol.39 , pp. 2449-2456
    • Umesawa, M.1    Iso, H.2    Ishihara, J.3    Saito, I.4    Kokubo, Y.5    Inoue, M.6
  • 26
    • 65549104323 scopus 로고    scopus 로고
    • Major types of dietary fat and risk of coronary heart disease: a pooled analysis of 11 cohort studies
    • Jakobsen M.U., O'Reilly E.J., Heitmann B.L., Pereira M.A., Bälter K., Fraser G.E., et al. Major types of dietary fat and risk of coronary heart disease: a pooled analysis of 11 cohort studies. Am J Clin Nutr 2009, 89:1425-1432.
    • (2009) Am J Clin Nutr , vol.89 , pp. 1425-1432
    • Jakobsen, M.U.1    O'Reilly, E.J.2    Heitmann, B.L.3    Pereira, M.A.4    Bälter, K.5    Fraser, G.E.6
  • 29
    • 0032763263 scopus 로고    scopus 로고
    • Dietary saturated fats and their food sources in relation to the risk of coronary heart disease in women
    • Hu F.B., Stampfer M.J., Manson J.E., Ascherio A., Colditz G.A., Speizer F.E. Dietary saturated fats and their food sources in relation to the risk of coronary heart disease in women. Am J Clin Nutr 1999, 70:1001-1008.
    • (1999) Am J Clin Nutr , vol.70 , pp. 1001-1008
    • Hu, F.B.1    Stampfer, M.J.2    Manson, J.E.3    Ascherio, A.4    Colditz, G.A.5    Speizer, F.E.6
  • 30
    • 0033560104 scopus 로고    scopus 로고
    • Dietary fat and coronary heart disease: a comparison of approaches for adjusting for total energy intake and modeling repeated dietary measurements
    • Hu F.B., Stampfer M.J., Rimm E., Ascherio A., Rosner B.A., Spiegelman D. Dietary fat and coronary heart disease: a comparison of approaches for adjusting for total energy intake and modeling repeated dietary measurements. Am J Epidemiol 1999, 149:531-540.
    • (1999) Am J Epidemiol , vol.149 , pp. 531-540
    • Hu, F.B.1    Stampfer, M.J.2    Rimm, E.3    Ascherio, A.4    Rosner, B.A.5    Spiegelman, D.6
  • 31
    • 0021367565 scopus 로고
    • Ten-year incidence of coronary heart disease in the Honolulu Heart Program. Relationship to nutrient intake
    • McGee D.L., Reed D.M., Yano K., Kagan A., Tillotson J. Ten-year incidence of coronary heart disease in the Honolulu Heart Program. Relationship to nutrient intake. Am J Epidemiol 1984, 119:667-676.
    • (1984) Am J Epidemiol , vol.119 , pp. 667-676
    • McGee, D.L.1    Reed, D.M.2    Yano, K.3    Kagan, A.4    Tillotson, J.5
  • 32
    • 0030017720 scopus 로고    scopus 로고
    • Dietary fat and risk of coronary heart disease in men: cohort follow up study in the United States
    • Ascherio A., Rimm E.B., Giovannucci E.L., Spiegelman D., Stampfer M., Willett W.C. Dietary fat and risk of coronary heart disease in men: cohort follow up study in the United States. BMJ 1996, 313:84-90.
    • (1996) BMJ , vol.313 , pp. 84-90
    • Ascherio, A.1    Rimm, E.B.2    Giovannucci, E.L.3    Spiegelman, D.4    Stampfer, M.5    Willett, W.C.6
  • 33
    • 0027216026 scopus 로고
    • Factors predictive of long-term coronary heart disease mortality among 10,059 male Israeli civil servants and municipal employees. A 23-year mortality follow-up in the Israeli Ischemic Heart Disease Study
    • Goldbourt U., Yaari S., Medalie J.H. Factors predictive of long-term coronary heart disease mortality among 10,059 male Israeli civil servants and municipal employees. A 23-year mortality follow-up in the Israeli Ischemic Heart Disease Study. Cardiology 1993, 82:100-121.
    • (1993) Cardiology , vol.82 , pp. 100-121
    • Goldbourt, U.1    Yaari, S.2    Medalie, J.H.3
  • 34
    • 0031009308 scopus 로고    scopus 로고
    • Intake of fatty acids and risk of coronary heart disease in a cohort of Finnish men. The Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study
    • Pietinen P., Ascherio A., Korhonen P., Hartman A.M., Willett W.C., Albanes D. Intake of fatty acids and risk of coronary heart disease in a cohort of Finnish men. The Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study. Am J Epidemiol 1997, 145:876-887.
    • (1997) Am J Epidemiol , vol.145 , pp. 876-887
    • Pietinen, P.1    Ascherio, A.2    Korhonen, P.3    Hartman, A.M.4    Willett, W.C.5    Albanes, D.6
  • 35
    • 0035076645 scopus 로고    scopus 로고
    • Types of dietary fat and risk of coronary heart disease: a critical review
    • Hu F.B., Manson J.E., Willett W.C. Types of dietary fat and risk of coronary heart disease: a critical review. J Am Coll Nutr 2001, 20:5-19.
    • (2001) J Am Coll Nutr , vol.20 , pp. 5-19
    • Hu, F.B.1    Manson, J.E.2    Willett, W.C.3
  • 36
    • 0141639681 scopus 로고    scopus 로고
    • Dietary fat intake and risk of stroke in male US healthcare professionals: 14 year prospective cohort study
    • He K., Merchant A., Rimm E.B., Rosner B.A., Stampfer M.J., Willet W.C. Dietary fat intake and risk of stroke in male US healthcare professionals: 14 year prospective cohort study. BMJ 2003, 327:777-782.
    • (2003) BMJ , vol.327 , pp. 777-782
    • He, K.1    Merchant, A.2    Rimm, E.B.3    Rosner, B.A.4    Stampfer, M.J.5    Willet, W.C.6
  • 37
    • 77950651061 scopus 로고    scopus 로고
    • Effects on coronary heart disease of increasing polyunsaturated fat in place of saturated fat: a systematic review and meta-analysis of randomized controlled trials
    • Mozaffarian D., Micha R., Wallace S. Effects on coronary heart disease of increasing polyunsaturated fat in place of saturated fat: a systematic review and meta-analysis of randomized controlled trials. PLoS Med 2010, 7:e1000252.
    • (2010) PLoS Med , vol.7
    • Mozaffarian, D.1    Micha, R.2    Wallace, S.3
  • 38
    • 78650012956 scopus 로고    scopus 로고
    • N-6 fatty acid-specific andmixed polyunsaturated dietary interventions have different effects onCHD risk: a meta-analysis of randomised controlled trials
    • Ramsden C.E., Hibbeln J.R., Majchrzak S.F., Davis J.M. N-6 fatty acid-specific andmixed polyunsaturated dietary interventions have different effects onCHD risk: a meta-analysis of randomised controlled trials. Br J Nutr 2010, 104:1586-1600.
    • (2010) Br J Nutr , vol.104 , pp. 1586-1600
    • Ramsden, C.E.1    Hibbeln, J.R.2    Majchrzak, S.F.3    Davis, J.M.4
  • 39
  • 40
    • 0029893967 scopus 로고    scopus 로고
    • Dietary fatty acids and progression of coronary artery disease in men
    • Watts G.F., Jackson P., Burke V., Lewis B. Dietary fatty acids and progression of coronary artery disease in men. Am J Clin Nutr 1996, 64:202-209.
    • (1996) Am J Clin Nutr , vol.64 , pp. 202-209
    • Watts, G.F.1    Jackson, P.2    Burke, V.3    Lewis, B.4
  • 41
    • 0013976945 scopus 로고
    • The effect of plasma cholesterol lowering diet in male survivors of myocardial infarction. A controlled clinical trial
    • Leren P. The effect of plasma cholesterol lowering diet in male survivors of myocardial infarction. A controlled clinical trial. Acta Med Scand Suppl 1966, 466:1-92.
    • (1966) Acta Med Scand Suppl , vol.466 , pp. 1-92
    • Leren, P.1


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