Editorial: Observational studies in ADHD: The effects of switching to modified-release methylphenidate preparations on clinical outcomes and adherence

European Child and Adolescent Psychiatry

Volumn 20, Issue SUPPL. 2, 2011, Pages

  Rothenberger, Aribert ^a   Döpfner, Manfred ^b  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b UNIVERSITY OF COLOGNE   (Germany)

Author keywords

ADHD; Children; Methylphenidate; Observational trials; Switching

Indexed keywords

METHYLPHENIDATE;

ATTENTION DEFICIT DISORDER; DRUG EFFICACY; DRUG RESPONSE; DRUG SUBSTITUTION; DRUG TOLERABILITY; DRUG WITHDRAWAL; HUMAN; MORNING DOSAGE; OBSERVATIONAL STUDY; PATIENT ATTITUDE; PATIENT COMPLIANCE; PATIENT SATISFACTION; REVIEW; STUDY DESIGN; TREATMENT OUTCOME;

ADOLESCENT; ATTENTION DEFICIT DISORDER WITH HYPERACTIVITY; CENTRAL NERVOUS SYSTEM STIMULANTS; CHILD; CHILD WELFARE; DELAYED-ACTION PREPARATIONS; DRUG ADMINISTRATION SCHEDULE; HUMANS; MEDICATION ADHERENCE; METHYLPHENIDATE; PSYCHOMOTOR PERFORMANCE; RESEARCH DESIGN; TREATMENT OUTCOME;

EID: 84855212856     PISSN: 10188827     EISSN: 1435165X     Source Type: Journal    
DOI: 10.1007/s00787-011-0201-5     Document Type: Review

References (34)

1. Antes G, Elm E (2008) Wie berichtet man eine Beobachtungsstudie? Deutsches Ärzteblatt 105:B6
2. Atzori P, Usala T, Carucci S, Danjou F, Zuddas A (2009) Predictive factors for persistent use and compliance of immediate-release methylphenidate: a 36-month naturalistic study. J Child Adolesc Psychopharmacol 19:673-681
3. Bakken RJ, Paczkowski M, Kramer HP, Axelson AA, Williams DW, Malcolm SK, Sumner CR, Kelsey DK (2008) Effects of atomoxetine on attention-deficit/ hyperactivity disorder in clinical pediatric treatment settings: a naturalistic study. Curr Med Res Opin 24:449-460 (Pubitemid 351294394)
4. Banaschewski T, Coghill D, Santosh P, Zuddas A, Asherson P, Buitelaar J, Danckaerts M, Dopfner M, Faraone SV, Rothenberger A, Sergeant J, Steinhausen HC, Sonuga-Barke EJ, Taylor E (2006) Long-acting medications for the hyperkinetic disorders. A systematic review and European treatment guideline. Eur Child Adolesc Psychiatry 15:476-495 (Pubitemid 46020533)
5. Banaschewski T, Rothenberger A (2010) Pharmakotherapie mit Stimulanzien bei Kindern und Jugendlichen. In: Steinhausen HC, Rothenberger A, Dopfner M (eds)) Handbuch ADHS. Kohlhammer, Stuttgart, pp 289-307
6. Becker A, Roessner V, Breuer D, Döpfner M, Rothenberger A (2011) Relationship between quality of life and psychopathological profile: data from an observational study in children with ADHD. Eur Child Adolesc Psychiatry. doi:10.1007/s00787-011-0204-2
7. Britton A, McKee M, Black N, McPherson K, Sanderson C, Bain C (1998) Choosing between randomised and non-randomised studies: a systematic review. Health Technol Assess 2:1-124
8. Chacko A, Newcorn JH, Feirsen N, Uderman JZ (2010) Improving medication adherence in chronic pediatric health conditions: a focus on ADHD in youth. Curr Pharm Des 16:2416-2423
9. Chou WJ, Chou MC, Tzang RF, Hsu YC, Gau SS, Chen SJ, Wu YY, Huang YF, Liang HY, Cheng H (2009) Better efficacy for the osmotic release oral system methylphenidate among poor adherents to immediate-release methylphenidate in the three ADHD subtypes. Psychiatry Clin Neurosci 63:167-175
10. Claudot F, Alla F, Fresson J, Calvez T, Coudane H, Bonaiti-Pellie C (2009) Ethics and observational studies in medical research: various rules in a common framework. Int J Epidemiol 38:1104-1108
11. Dirksen SJ, D'Imperio JM, Birdsall D, Hatch SJ (2002) A postmarketing clinical experience study of Metadate CD. Curr Med Res Opin 18:371-380 (Pubitemid 35448533)
12. Döpfner M, Görtz-Dorten A, Breuer D, Rothenberger A (2011) An observational study of once-daily modified-release methylphenidate in ADHD: effectiveness on symptoms and impairment, and safety. Eur Child Adolesc Psychiatry. doi:10.1007/s00787-011-0202-4
13. Döpfner M, Breuer D, Ose C, Fischer R (2011) Methylphenidat mit modifizierter Freisetzung in der Routineversorgung - Wirksamkeit und Verträglichkeit eines Methylphenidat-Retard Präparates im klinischen Urteil und im Elternurteil - eine offene multizentrische Studie an Kindern und Jugendlichen mit ADHS. Monatsschrift fur Kinderheilkunde. doi:10.1007/s00112- 011-2413-7
14. Döpfner M, Breuer D, Walter D, Rothenberger A (2011) An observational study of once-daily modified-release methylphenidate in ADHD: the effect of previous treatment on ADHD symptoms, other externalising symptoms and quality-of-life outcomes. Eur Child Adolesc Psychiatry. doi:10.1007/s00787-011- 0205-1
15. Döpfner M, Gerber WD, Banaschewski T, Breuer D, Freisleder FJ, Gerber-von MG, Gunter M, Hassler F, Ose C, Rothenberger A, Schmeck K, Sinzig J, Stadler C, Uebel H, Lehmkuhl G (2004) Comparative efficacy of once-a-day extended-release methylphenidate, two-times-daily immediate-release methylphenidate, and placebo in a laboratory school setting. Eur Child Adolesc Psychiatry 13(Suppl 1):93-101
16. Findling RL, Quinn D, Hatch SJ, Cameron SJ, DeCory HH, McDowell M (2006) Comparison of the clinical efficacy of twicedaily Ritalin and once-daily Equasym XL with placebo in children with Attention Deficit/Hyperactivity Disorder. Eur Child Adolesc Psychiatry 15:450-459 (Pubitemid 46020530)
17. Gau SS, Chen SJ, Chou WJ, Cheng H, Tang CS, Chang HL, Tzang RF, Wu YY, Huang YF, Chou MC, Liang HY, Hsu YC, Lu HH, Huang YS (2008) National survey of adherence, efficacy, and side effects of methylphenidate in children with attentiondeficit/ hyperactivity disorder in Taiwan. J Clin Psychiatry 69:131-140 (Pubitemid 351282007)
18. Gau SS, Shen HY, Soong WT, Gau CS (2006) An open-label, randomized, active-controlled equivalent trial of osmotic release oral system methylphenidate in children with attention-deficit/ hyperactivity disorder in Taiwan. J Child Adolesc Psychopharmacol 16:441-455 (Pubitemid 44681464)
19. Hammer GP, du Prel JB, Blettner M (2009) Vermeidung verzerrter Ergebnisse in Beobachtungsstudien. Deutsches Ä rzteblatt 41:664-668
20. Heger S, Trott GE, Meusers M, Schulz E, Rothenberger A, Rettig K, Medori R, Schreiner A, Remschmidt H (2006) Switching from a short-acting to a long-acting methylphenidate preparation: a multicentre, open study in children with ADHD. Z Kinder Jugendpsychiatr Psychother 34:257-265 (Pubitemid 44204675)
21. Hoare P, Remschmidt H, Medori R, Ettrich C, Rothenberger A, Santosh P, Schmit M, Spender Q, Tamhne R, Thompson M, Tinline C, Trott GE (2005) 12-month efficacy and safety of OROS MPH in children and adolescents with attention-deficit/ hyperactivity disorder switched from MPH. Eur Child Adolesc Psychiatry 14:305-309
22. Hoekstra PJ (2010) The need for a long-term perspective in child and adolescent psychiatry. Eur Child Adolesc Psychiatry 19:687-688
23. Hollingworth SA, Nissen LM, Stathis SS, Siskind DJ, Varghese JM, Scott JG (2011) Australian national trends in stimulant dispensing: 2002-2009. Aust N Z J Psychiatry 45:332-336
24. Maia CR, Matte BC, Ludwig HT, Rohde LA (2008) Switching from methylphenidate immediate release to MPH-SODAS in attention-deficit/ hyperactivity disorder. Eur Child Adolesc Psychiatry 17:133-142 (Pubitemid 351640934)
25. McKee M, Britton A, Black N, McPherson K, Sanderson C, Bain C (1999) Methods in health services research. Interpreting the evidence: choosing between randomised and non-randomised studies. BMJ 319:312-315 (Pubitemid 29353952)
26. Rapoport JL (2009) Personal reflections on observational and experimental research approaches to childhood psychopathology. J Child Psychol Psychiatry 50:36-43
27. Remschmidt H, Hoare P, Ettrich C, Rothenberger A, Santosh P, Schmidt M, Spender Q, Tamhne R, Thompson M, Tinline C, Trott GE, Medori R (2005) Symptom control in children and adolescents with attention-deficit/hyperactivity disorder on switching from immediate-release MPH to OROS MPH Results of a 3-week open-label study. Eur Child Adolesc Psychiatry 14:297-304
28. Rothenberger A, Becker A, Breuer D, Döpfner M (2011) An observational study of once-daily modified-release methylphenidate in ADHD: quality of life, satisfaction with treatment and adherence. Eur Child Adolesc Psychiatry. doi:10.1007/s00787-011-0203-3
29. Rothenberger A, Coghill D, Döpfner M, Falissard B, Steinhausen HC (2006) ADORE (Attention-Deficit/Hyperactivity Disorder Observational Research in Europe). Naturalistic-observational studies in the framework of ADHD health care. Eur Child Adolesc Psychiatry 15:1-3
30. Rothwell PM (2005) External validity of randomised controlled trials: "to whom do the results of this trial apply?". Lancet 365:82-93 (Pubitemid 40082150)
31. Spencer TJ, Biederman J, Ciccone PE, Madras BK, Dougherty DD, Bonab AA, Livni E, Parasrampuria DA, Fischman AJ (2006) PET study examining pharmacokinetics, detection and likeability, and dopamine transporter receptor occupancy of short- and longacting oral methylphenidate. Am J Psychiatry 163:387-395 (Pubitemid 44469379)
32. von Elm E, Altman DG, Egger M, Pocock SJ, Gotzsche PC, Vandenbroucke JP (2007) The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies. PLoS Med 4:e296
33. Winterstein AG, Gerhard T, Shuster J, Zito J, Johnson M, Liu H, Saidi A (2008) Utilization of pharmacologic treatment in youths with attention deficit/hyperactivity disorder in Medicaid database. Ann Pharmacother 42:24-31
34. Zoega H, Baldursson G, Halldorsson M (2007) Use of methylphenidate among children in Iceland 1989-2006. Laeknabladid 93:825-832