High content live cell imaging for the discovery of new antimalarial marine natural products

BMC Infectious Diseases

Volumn 12, Issue , 2012, Pages

  Cervantes, Serena ^a   Stout, Paige E ^b   Prudhomme, Jacques ^a   Engel, Sebastian ^b   Bruton, Matthew ^a   Cervantes, Michael ^a   Carter, David ^a   Tae Chang, Young ^c,d   Hay, Mark E ^b   Aalbersberg, William ^e   Kubanek, Julia ^b   Le Roch, Karine G ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

^c AGENCY FOR SCIENCE   (Singapore)

^d AGENCY FOR SCIENCE   (Singapore)

^e UNIVERSITY OF THE SOUTH PACIFIC   (Fiji)

Author keywords

Antimalarial; Drug screening; High throughput screening; Natural products; Plasmodium falciparum

Indexed keywords

ANTIMALARIAL AGENT; BROMOPHYCOLIDE A; NATURAL PRODUCT; UNCLASSIFIED DRUG; BIOLOGICAL PRODUCT;

ANTIMALARIAL ACTIVITY; ARTICLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG SCREENING; ERYTHROCYTE; FLUORESCENCE; HIGH CONTENT LIVE CELL IMAGING; IC 50; IMAGE ANALYSIS; IMAGING; IN VITRO STUDY; MARINE SPECIES; NONHUMAN; PHENOTYPE; PLASMODIUM FALCIPARUM; CYTOLOGY; DRUG EFFECT; GROWTH, DEVELOPMENT AND AGING; HUMAN; IMAGE PROCESSING; ISOLATION AND PURIFICATION; METHODOLOGY; PARASITOLOGY; VALIDATION STUDY;

ANTIMALARIALS; BIOLOGICAL AGENTS; CYTOLOGICAL TECHNIQUES; DRUG EVALUATION, PRECLINICAL; ERYTHROCYTES; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; PLASMODIUM FALCIPARUM;

EID: 84855212751     PISSN: None     EISSN: 14712334     Source Type: Journal    
DOI: 10.1186/1471-2334-12-1     Document Type: Article

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