Tumor necrosis factor (TNF) receptor shedding controls thresholds of innate immune activation that balance opposing TNF functions in infectious and inflammatory diseases

Journal of Experimental Medicine

Volumn 200, Issue 3, 2004, Pages 367-376

  Xanthoulea, Sofia ^a   Pasparakis, Manolis ^b   Kousteni, Stavroula ^c   Brakebusch, Cord ^d,f   Wallach, David ^d   Bauer, Jan ^e   Lassmann, Hans ^e   Kollias, George ^a  

^a BIOMEDICAL SCIENCES RESEARCH CENTER ALEXANDER FLEMING   (Greece)

^b EUROPEAN MOLECULAR BIOLOGY LABORATORY EMBL   (Italy)

^c UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^d WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^e UNIVERSITY OF VIENNA   (Austria)

^f MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

Author keywords

Arthritis; Chronic hepatitis; EAE; LPS toxicity; TRAPS

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; CELL SURFACE RECEPTOR; ETANERCEPT; NITRIC OXIDE; RECOMBINANT TUMOR NECROSIS FACTOR; RNA; TUMOR NECROSIS FACTOR RECEPTOR; TUMOR NECROSIS FACTOR RECEPTOR 1;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL CELL; ANIMAL MODEL; ARTHRITIS; ARTICLE; AUTOIMMUNE DISEASE; CHRONIC HEPATITIS; COLONY FORMING UNIT; DISEASE PREDISPOSITION; EMBRYO; ENZYME LINKED IMMUNOSORBENT ASSAY; FEVER; FIBROBLAST; FLOW CYTOMETRY; GENOTYPE; HISTOPATHOLOGY; IMMUNIZATION; IMMUNOHISTOCHEMISTRY; INFECTION; INFLAMMATION; LISTERIA MONOCYTOGENES; LYMPHOCYTE PROLIFERATION; MACROPHAGE; MOUSE; MULTIPLE SCLEROSIS; NONHUMAN; NORTHERN BLOTTING; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; T LYMPHOCYTE; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED PERIODIC SYNDROME;

AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, CD; ARTHRITIS; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; HEPATITIS, CHRONIC; IMMUNITY, NATURAL; LIPOPOLYSACCHARIDES; LISTERIA INFECTIONS; MICE; MICE, INBRED C57BL; MOLECULAR SEQUENCE DATA; RECEPTORS, TUMOR NECROSIS FACTOR; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE I; TUMOR NECROSIS FACTOR-ALPHA;

EID: 3543079892     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20040435     Document Type: Article

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