Conformational studies of immunodominant myelin basic protein 1-11 analogues using NMR and molecular modeling

Journal of Computer-Aided Molecular Design

Volumn 25, Issue 11, 2011, Pages 1019-1032

  Laimou, Despina ^a   Lazoura, Eliada ^b   Troganis, Anastassios N ^c   Matsoukas, Minos Timotheos ^a   Deraos, Spyros N ^a   Katsara, Maria ^a,b   Matsoukas, John ^a   Apostolopoulos, Vasso ^b   Tselios, Theodore V ^a  

^a UNIVERSITY OF PATRAS   (Greece)

^b BURNET INSTITUTE   (Australia)

^c UNIVERSITY OF IOANNINA   (Greece)

Author keywords

Central nervous system; Experimental autoimmune encephalomyelitis; Multiple sclerosis; Myelin basic protein; T cell receptor; ajor histocompatibility complex class II

Indexed keywords

AMINO ACIDS; CELL MEMBRANES; CONFORMATIONS; EPITOPES; GOLD COMPOUNDS; MOLECULAR DYNAMICS; NUCLEAR MAGNETIC RESONANCE; T-CELLS;

CENTRAL NERVOUS SYSTEMS; CLASS II; COMPLEX CLASS; CONFORMATIONAL STUDY; EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS; HISTOCOMPATIBILITY COMPLEXES; MULTIPLE SCLEROSIS; MYELIN BASIC PROTEIN; T CELLS RECEPTORS; ΜAJOR HISTOCOMPATIBILITY COMPLEX CLASS II;

PEPTIDES;

ACETYLATED MYELIN BASIC PROTEIN[1-11]; ALANINE MYELIN BASIC PROTEIN[1-11]; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MYELIN BASIC PROTEIN; T LYMPHOCYTE RECEPTOR; TYROSINE MYELIN BASIC PROTEIN[1-11]; UNCLASSIFIED DRUG;

ALLERGIC ENCEPHALOMYELITIS; AMINO ACID SEQUENCE; ANTIGEN BINDING; ARTICLE; BINDING SITE; CALCULATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; HYDROGEN BOND; MOLECULAR DYNAMICS; MOLECULAR MODEL; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN INTERACTION;

EID: 84855188989     PISSN: 0920654X     EISSN: 15734951     Source Type: Journal    
DOI: 10.1007/s10822-011-9481-6     Document Type: Article

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