Pretreatment with the ciclosporin derivative NIM811 reduces delayed neuronal death in the hippocampus after transient forebrain ischaemia

Journal of Pharmacy and Pharmacology

Volumn 62, Issue 4, 2010, Pages 485-490

  Hokari, Masaaki ^a   Kuroda, Satoshi ^a   Iwasaki, Yoshinobu ^a  

^a HOKKAIDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Delayed neuronal death; Hippocampus; NIM811; Reduced mitochondrial permeability transition; Transient forebrain ischaemia

Indexed keywords

5,5',6,6' TETRACHLORO 1,1',3,3' TETRAETHYLBENZIMIDAZOLOCARBOCYANINE IODIDE; CARBOCYANINE; CYCLOSPORIN A; CYCLOSPORIN A [4 N METHYLISOLEUCINE]; DNA NUCLEOTIDYLEXOTRANSFERASE; GLUTAMIC ACID; PHOSPHATE BUFFERED SALINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN REGION; C57BL 6 MOUSE; CAROTID ARTERY OBSTRUCTION; COMMON CAROTID ARTERY; CONTROLLED STUDY; HIPPOCAMPUS; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; NERVE CELL NECROSIS; NICK END LABELING; NONHUMAN; TRANSIENT ISCHEMIC ATTACK;

ANIMALS; APOPTOSIS; BENZIMIDAZOLES; CARBOCYANINES; CYCLOSPORINE; GLUTAMIC ACID; HIPPOCAMPUS; IN SITU NICK-END LABELING; ISCHEMIC ATTACK, TRANSIENT; MALE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; MICE, INBRED C57BL; MITOCHONDRIA; NEURONS; NEUROPROTECTIVE AGENTS; PERMEABILITY; PROSENCEPHALON;

EID: 77952814930     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/jpp.62.04.0011     Document Type: Article

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