Modulation of PGE 2-induced EP4 expression on Snail signaling and the impact on epithelial-mesenchymal transition: Significance of EP4 antagonism

Anticancer Research

Volumn 31, Issue 12, 2011, Pages 4347-4357

  Kim, Hye Na ^a   Narayanan, Narayanan K ^a   Lasano, Salamia ^a   Narayanan, Bhagavathi ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

EP4; Epithelial mesencymal transition; P Akt; PGE 2; Prostate cancer; Snail

Indexed keywords

6 ISOPROPOXY 9 OXO 2 XANTHENECARBOXYLIC ACID; 7 [5 (4 BIPHENYLYLMETHOXY) 2 MORPHOLINO 3 OXOCYCLOPENTYL] 4 HEPTENOIC ACID; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROSTAGLANDIN E RECEPTOR 4; PROTEIN KINASE B; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR SNAIL; ZINC FINGER PROTEIN; PROSTAGLANDIN E2; SNAIL FAMILY TRANSCRIPTION FACTORS; TRANSCRIPTION FACTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CANCER CELL; CANCER GROWTH; CELL CYCLE ARREST; CELL MIGRATION; DNA BINDING; EPITHELIAL MESENCHYMAL TRANSITION; FEMALE; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN EXPRESSION; ANIMAL; CELL MOTION; CELL PROLIFERATION; DISEASE COURSE; DRUG ANTAGONISM; ENZYME IMMUNOASSAY; FLUORESCENCE MICROSCOPY; MALE; METABOLISM; METHODOLOGY; MOUSE MUTANT; PROSTATE TUMOR; TUMOR CELL LINE;

ANIMALS; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; DINOPROSTONE; DISEASE PROGRESSION; EPITHELIAL-MESENCHYMAL TRANSITION; HUMANS; IMMUNOENZYME TECHNIQUES; MALE; MICE; MICE, KNOCKOUT; MICROSCOPY, FLUORESCENCE; PROSTATIC NEOPLASMS; RECEPTORS, PROSTAGLANDIN E, EP4 SUBTYPE; RNA, SMALL INTERFERING; TRANSCRIPTION FACTORS;

EID: 84855170459     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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