Effects of hydrogen sulfide on rat pancreatic stellate cells

Pancreas

Volumn 41, Issue 1, 2012, Pages 74-83

  Schwer, Christian I ^a   Stoll, Patrick ^a   Goebel, Ulrich ^a   Buerkle, Hartmut ^a   Hoetzel, Alexander ^a   Schmidt, Rene ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

Author keywords

heme oxygenase 1; hydrogen sulfide; migration; pancreatic fibrosis; pancreatic stellate cells; proliferation

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; BROXURIDINE; CASPASE 3; COLLAGEN TYPE 1; FIBRONECTIN; HEME OXYGENASE 1; HEME OXYGENASE 2; HYDROGEN SULFIDE; LACTATE DEHYDROGENASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; SMALL INTERFERING RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CELL COUNT; CELL CYCLE PROGRESSION; CELL DEATH; CELL ISOLATION; CELL MIGRATION; CELL PROLIFERATION; CELL TRANSDIFFERENTIATION; CONTROLLED STUDY; CYTOTOXICITY; DRUG INHIBITION; EXTRACELLULAR MATRIX; FLOW CYTOMETRY; GENETIC TRANSFECTION; MALE; NONHUMAN; PANCREATIC STELLATE CELL; PRIORITY JOURNAL; RAT; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WOUND HEALING;

ACTINS; ANIMALS; BLOTTING, WESTERN; CELL MOVEMENT; CELL PROLIFERATION; CELLS, CULTURED; COLLAGEN TYPE I; EXTRACELLULAR MATRIX; FIBRONECTINS; GENE EXPRESSION; HEME OXYGENASE-1; HYDROGEN SULFIDE; MALE; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASES; PANCREATIC STELLATE CELLS; RATS; RATS, WISTAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SULFIDES;

EID: 84655167117     PISSN: 08853177     EISSN: 15364828     Source Type: Journal    
DOI: 10.1097/MPA.0b013e318223645b     Document Type: Article

References (38)

1. Apte MV, Pirola RC, Wilson JS. Battle-scarred pancreas: role of alcohol and pancreatic stellate cells in pancreatic fibrosis. J Gastroenterol Hepatol. 2006;21(suppl 3):S97-S101. (Pubitemid 44266561)
2. Omary MB, Lugea A, Lowe AW, et al. The pancreatic stellate cell: a star on the rise in pancreatic diseases. J Clin Invest. 2007;117:50-59. (Pubitemid 46048449)
3. Masamune A, Watanabe T, Kikuta K, et al. Roles of pancreatic stellate cells in pancreatic inflammation and fibrosis. Clin Gastroenterol Hepatol. 2009;7:S48-S54.
4. Haber PS, Keogh GW, Apte MV, et al. Activation of pancreatic stellate cells in human and experimental pancreatic fibrosis. Am J Pathol. 1999;155:1087-1095. (Pubitemid 29488916)
5. Apte MV, Haber PS, Applegate TL, et al. Periacinar stellate shaped cells in rat pancreas: identification, isolation, and culture. Gut. 1998;43:128-133. (Pubitemid 28335501)
6. Bachem MG, Schneider E, Gross H, et al. Identification, culture, and characterization of pancreatic stellate cells in rats and humans. Gastroenterology. 1998;115:421-432.
7. Shimizu K, Kobayashi M, Tahara J, et al. Cytokines and peroxisome proliferatorYactivated receptor γ ligand regulate phagocytosis by pancreatic stellate cells. Gastroenterology. 2005;128:2105-2118. (Pubitemid 40824717)
8. Apte MV, Haber PS, Darby SJ, et al. Pancreatic stellate cells are activated by proinflammatory cytokines: implications for pancreatic fibrogenesis. Gut. 1999;44:534-541. (Pubitemid 29169954)
9. 2S be the third endogenous gaseous transmitter? FASEB J. 2002;16:1792-1798.
10. Wang R. The gasotransmitter role of hydrogen sulfide. Antioxid Redox Signal. 2003;5:493-501. (Pubitemid 37087410)
11. Kim HP, Ryter SW, Choi AM. CO as a cellular signaling molecule. Annu Rev Pharmacol Toxicol. 2006;46:411-449. (Pubitemid 43271196)
12. Schwer CI, Mutschler M, Stoll P, et al. Carbon monoxide releasing molecule-2 inhibits pancreatic stellate cell proliferation by activating p38 mitogen-activated protein kinase/heme oxygenase-1 signaling. Mol Pharmacol. 2010;77:660-669.
13. Smith RP, Gosselin RE. Hydrogen sulfide poisoning. J Occup Med. 1979;21:93-97. (Pubitemid 9120131)
14. Zhao W, Zhang J, Lu Y, et al. The vasorelaxant effect of H(2)S as a novel endogenous gaseous K(ATP) channel opener. EMBO J. 2001;20:6008-6016. (Pubitemid 33049276)
15. Bhatia M, Wong FL, Fu D, et al. Role of hydrogen sulfide in acute pancreatitis and associated lung injury. FASEB J. 2005;19:623-625. (Pubitemid 40471265)
16. Eto K, Kimura H. The production of hydrogen sulfide is regulated by testosterone and S-adenosyl-L-methionine in mouse brain. J Neurochem. 2002;83:80-86.
17. Cip/WAK-1. J Biol Chem. 2004;279: 49199-49205. (Pubitemid 39625803)
18. Valitutti S, Castellino F, Musiani P. Effect of sulfurous (thermal) water on T lymphocyte proliferative response. Ann Allergy. 1990;65:463-468.
19. 2S regulates perfusion pressure in both the isolated and perfused normal rat liver and in cirrhosis. Hepatology. 2005;42:539-548. (Pubitemid 41233646)
20. 2S, endoplasmic reticulum stress, and apoptosis of insulin-secreting β cells. J Biol Chem. 2007;282:16567-16576. (Pubitemid 47100397)
21. 2S-induced pancreatic acinar cell apoptosis is mediated via JNK and p38 MAP kinase. J Cell Mol Med. 2008;12:1374-1383.
22. Nishimura S, Fukushima O, Ishikura H, et al. Hydrogen sulphide as a novel mediator for pancreatic pain in rodents. Gut. 2009;58:762-770.
23. 1, type I collagen, and CTGF in primary culture or freshly isolated cells. Acta Med Okayama. 2002;56:211-218. (Pubitemid 135689620)
24. Szabo C. Hydrogen sulphide and its therapeutic potential. Nat Rev Drug Discov. 2007;6:917-935. (Pubitemid 350042399)
25. Li L, Bachem MG, Zhou S, et al. Pancreatitis-associated protein inhibits human pancreatic stellate cell MMP-1 and -2, TIMP-1 and -2 secretion and RECK expression. Pancreatology. 2009;9:99-110.
26. Li L, Bimmler D, Graf R, et al. PSP/reg inhibits cultured pancreatic stellate cell and regulates MMP/ TIMP ratio. Eur J Clin Invest. 2011;41(2):151-158.
27. Rockey DC, Housset CN, Friedman SL. Activation-dependent contractility of rat hepatic lipocytes in culture and in vivo. J Clin Invest. 1993;92:1795-1804. (Pubitemid 23304545)
28. Schwer CI, Guerrero AM, Humar M, et al. Heme oxygenase-1 inhibits the proliferation of pancreatic stellate cells by repression of the extracellular signalYregulated kinase1/2 pathway. J Pharmacol Exp Ther. 2008;327:863-871.
29. Yang GD, Wang R. H(2)S and cellular proliferation and apoptosis. Sheng Li Xue Bao. 2007;59:133-140.
30. Du J, Hui Y, Cheung Y, et al. The possible role of hydrogen sulphide as a smooth muscle cell proliferation inhibitor in rat cultured cells. Heart Vessels. 2004;19:75-80. (Pubitemid 38489034)
31. Deplancke B, Gaskins HR. Hydrogen sulfide induces serum-independent cell cycle entry in nontransformed rat intestinal epithelial cells. FASEB J. 2003;17:1310-1312.
32. Cai WJ, Wang MJ, Ju LH, et al. Hydrogen sulfide induces human colon cancer cell proliferation: role of Akt, ERK and p21. Cell Biol Int. 2010;34:565-572.
33. Baskar R, Li L, Moore PK. Hydrogen sulfide-induces DNA damage and changes in apoptotic gene expression in human lung fibroblast cells. FASEB J. 2007;21:247-255. (Pubitemid 46052563)
34. Wang R. Hydrogen sulfide: a new EDRF. Kidney Int. 2009; 76:700-704.
35. Oh GS, Pae HO, Lee BS, et al. Hydrogen sulfide inhibits nitric oxide production and nuclear factor-JB via heme oxygenase-1 expression in RAW264.7 macrophages stimulated with lipopolysaccharide. Free Radic Biol Med. 2006;41:106-119.
36. Taille C, Almolki A, Benhamed M, et al. Heme oxygenase inhibits human airway smooth muscle proliferation via a bilirubin-dependent modulation of ERK1/2 phosphorylation. J Biol Chem. 2003;278: 27160-27168. (Pubitemid 36876872)
37. Durante W, Peyton KJ, Schafer AI. Platelet-derived growth factor stimulates heme oxygenase-1 gene expression and carbon monoxide production in vascular smooth muscle cells. Arterioscler Thromb Vasc Biol. 1999;19:2666-2672. (Pubitemid 29536041)
38. Maines MD, Trakshel GM. Differential regulation of heme oxygenase isozymes by Sn- and Zn-protoporphyrins: possible releVance to suppression of hyperbilirubinemia. Biochim Biophys Acta. 1992;1131:166-174.