Preparation and in vitro-in vivo evaluation of none gastric resident dipyridamole (DIP) sustained-release pellets with enhanced bioavailability

International Journal of Pharmaceutics

Volumn 422, Issue 1-2, 2012, Pages 9-16

  Xu, Lishuang ^a   Luo, Yanfei ^a   Feng, Jia ^a   Xu, Ming ^a   Tao, Xiaoguang ^a   He, Haibing ^a   Tang, Xing ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Bioavailability; Dipyridamole; pH dependence; Sustained release pellets

Indexed keywords

CITRIC ACID; DIPYRIDAMOLE; POLYMER;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DOG; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG PELLET; EVALUATION; GASTROINTESTINAL TRACT; IN VITRO STUDY; IN VIVO STUDY; MALE; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; PELLET EXTRUSION; PH; PRIORITY JOURNAL; SPHERONIZATION; SUSTAINED RELEASE PREPARATION; TIME TO MAXIMUM PLASMA CONCENTRATION;

ADMINISTRATION, ORAL; ANIMALS; BIOLOGICAL AVAILABILITY; CHEMISTRY, PHARMACEUTICAL; CITRIC ACID; DIPYRIDAMOLE; DOGS; DRUG COMPOUNDING; HYDROGEN-ION CONCENTRATION; METHACRYLATES; MICROSCOPY, ELECTRON, SCANNING; MODELS, BIOLOGICAL; PLATELET AGGREGATION INHIBITORS; POLYMERS; SOLUBILITY; SURFACE PROPERTIES; TABLETS, ENTERIC-COATED; TECHNOLOGY, PHARMACEUTICAL;

EID: 84655165086     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2011.10.014     Document Type: Article

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