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Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 1, 2012, Pages 493-496

Developing potent backbone cyclic peptides bearing the shared epitope sequence as rheumatoid arthritis drug-leads

(6) Naveh, Shirly a Tal Gan, Yftah a Ling, Song b Hoffman, Amnon c Holoshitz, Joseph b Gilon, Chaim a

a HEBREW UNIVERSITY OF JERUSALEM (Israel)

b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL (United States)

c HEBREW UNIVERSITY OF JERUSALEM (Israel)

Author keywords

Backbone cyclization; Peptidomimetics; Rheumatoid arthritis

Indexed keywords

C(HS2 4); C(HS4 4); C(HS6 4); CHYMOTRYPSIN; CYCLOPEPTIDE; EPITOPE; NITRIC OXIDE; TRYPSIN; UNCLASSIFIED DRUG;

ARTICLE; CIRCULAR DICHROISM; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DRUG DESIGN; ENZYME DEGRADATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; RHEUMATOID ARTHRITIS;

ARTHRITIS, RHEUMATOID; CHEMISTRY, PHARMACEUTICAL; CIRCULAR DICHROISM; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DESIGN; EPITOPES; HUMANS; INFLAMMATION; MODELS, CHEMICAL; NITRIC OXIDE; PEPTIDES; PEPTIDES, CYCLIC; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; TIME FACTORS;

EID: 84655161547 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2011.10.098 Document Type: Article

Times cited : (18)

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