Lymphocyte α-kinase is a gout-susceptible gene involved in monosodium urate monohydrate-induced inflammatory responses

Journal of Molecular Medicine

Volumn 89, Issue 12, 2011, Pages 1241-1251

  Wang, Shu Jung ^a   Tu, Hung Pin ^b   Ko, Albert Min Shan ^c   Chiang, Shang Lun ^b   Chiou, Shean Jaw ^b   Lee, Su Shin ^d   Tsai, Yi Shan ^a   Lee, Chi Pin ^b   Ko, Ying Chin ^a,b  

^a KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^b KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^c Max Planck Institute for Evolutionary Anthropology   (Germany)

^d KAOHSIUNG MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

ALPK1; Gout; Inflammatory responses; Monocytes; Monosodium urate monohydrate

Indexed keywords

CYTOKINE; INTERLEUKIN 1BETA; INTERLEUKIN 8; JANUS KINASE; LYMPHOCYTE ALPHA KINASE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHOTRANSFERASE; SYNAPTOPHYSIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; URATE;

ARTICLE; CELL LINE; CELL STRAIN HEK293; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; GENE EXPRESSION; GENE FUNCTION; GENE OVEREXPRESSION; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENETIC TRANSFECTION; GOUT; HUMAN; HUMAN CELL; MALE; MICROARRAY ANALYSIS; MONOCYTE; PATHOGENESIS; REAL TIME POLYMERASE CHAIN REACTION; RNA INTERFERENCE; WESTERN BLOTTING;

CELL LINE, TUMOR; ENZYME INDUCTION; GENE EXPRESSION PROFILING; GENETIC PREDISPOSITION TO DISEASE; GOUT; HEK293 CELLS; HUMANS; INFLAMMATION; MALE; PROTEIN KINASES; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER; URIC ACID;

EID: 84555196579     PISSN: 09462716     EISSN: 14321440     Source Type: Journal    
DOI: 10.1007/s00109-011-0796-5     Document Type: Article

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