High-throughput microtitre plate-based assay for DNA topoisomerases

Methods in Molecular Biology

Volumn 815, Issue , 2012, Pages 229-239

  Taylor, James A ^a   Burton, Nicolas P ^b   Maxwell, Anthony ^a  

^a JOHN INNES CENTRE   (United Kingdom)

^b NORWICH RESEARCH PARK   (United Kingdom)

Author keywords

DNA gyrase; High throughput screening; Relaxation; Supercoiling; Topoisomerase; Triplex formation

Indexed keywords

DNA; DNA TOPOISOMERASE (ATP HYDROLYSING); DNA TOPOISOMERASE INHIBITOR; ESCHERICHIA COLI PROTEIN; TRIPLEX DNA;

ARTICLE; CHEMISTRY; CONFORMATION; DNA SUPERCOILING; DRUG ANTAGONISM; ENZYME ASSAY; HIGH THROUGHPUT SCREENING; HUMAN; ISOLATION AND PURIFICATION; METHODOLOGY; MOLECULAR LIBRARY; PLASMID;

DNA; DNA GYRASE; DNA, SUPERHELICAL; ENZYME ASSAYS; ESCHERICHIA COLI PROTEINS; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; NUCLEIC ACID CONFORMATION; PLASMIDS; SMALL MOLECULE LIBRARIES; TOPOISOMERASE INHIBITORS;

EID: 84555189592     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-61779-424-7_17     Document Type: Article

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