Head and neck lymphatic tumors and bony abnormalities: A clinical and molecular review

Lymphatic Research and Biology

Volumn 9, Issue 4, 2011, Pages 205-212

  Balakrishnan, Karthik ^a   Majesky, Mark ^a   Perkins, Jonathan A ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DISEASE ASSOCIATION; HEAD AND NECK TUMOR; LYMPHANGIOGENESIS; LYMPHATIC SYSTEM TUMOR; PRIORITY JOURNAL; REVIEW; SKELETON MALFORMATION;

BONE AND BONES; BONE DISEASES; ENDOTHELIAL CELLS; EXTRACELLULAR MATRIX; HEAD AND NECK NEOPLASMS; HUMANS; LYMPHATIC VESSEL TUMORS; SIGNAL TRANSDUCTION;

EID: 84555179034     PISSN: 15396851     EISSN: 15578585     Source Type: Journal    
DOI: 10.1089/lrb.2011.0018     Document Type: Review

References (59)

1. Perkins JA, Manning SC, Tempero RM, Cunningham MJ, Edmonds JL Jr, Hoffer FA, Egbert MA. Lymphatic mal-formations: Review of current treatment. Otolaryngol Head Neck Surg 2010;142:795-803.
2. Boyd JB, Mulliken JB, Kaban LB, Upton J III, Murray JE. Skeletal changes associated with vascular malformations. Plast Reconstr Surg 1984;74:789-795. (Pubitemid 15222804)
3. Lee S, Finn L, Sze RW, Perkins JA, Sie KC. Gorham Stout syndrome (disappearing bone disease): Two additional case reports and a review of the literature. Arch Otolaryngol Head Neck Surg 2003;129:1340-1343. (Pubitemid 37523111)
4. Osborne TE, Levin LS, Tilghman DM, Haller JA. Surgical correction of mandibulofacial deformities secondary to large cervical cystic hygromas. J Oral Maxillofac Surg 1987;45: 1015-1021. (Pubitemid 18032279)
5. Padwa BL, Hayward PG, Ferraro NF, Mulliken JB. Cervi-cofacial lymphatic malformation: Clinical course, surgical intervention, and pathogenesis of skeletal hypertrophy. Plast Reconstr Surg 1995;95:951-960.
6. Lu P, Takai K, Weaver VM, Werb Z. Extracellular matrix degradation and remodeling in development and disease. Cold Spring Harb Perspect Biol. 2011; Dec 1; 3(12). pii: a005058. doi: 10.1101/cghperspect.a005058.
7. Edwards JR, Williams K, Kindblom LG, Meis-Kindblom JM, Hogendoorn PC, Hughes D, Forsyth RG, Jackson D, Atha-nasou NA Lymphatics and bone. Hum Pathol 2008;39:49-55. (Pubitemid 350216159)
8. Jin ZW, Nakamura T, Yu HC, Kimura W, Murakami G, Cho BH. Fetal anatomy of peripheral lymphatic vessels: A D2-40 immunohistochemical study using an 18-week human fetus (CRL 155mm). J Anat 2010;216:671-682.
9. O TM, Kwak R, Portnof JE, Berke DM, Lipari B, Waner M. Analysis of skeletal mandibular abnormalities associated with cervicofacial lymphatic malformations. Laryngoscope 2011;121:91-101.
10. Zukerberg LR, Nickoloff BJ, Weiss SW. Kaposiform he-mangioendothelioma of infancy and childhood: An aggres-sive neoplasm associated with Kasabach-Merritt syndrome and lymphangiomatosis. Am J Surg Pathol 1993;17:321-328. (Pubitemid 23096821)
11. Franchi A, Bertoni F, Bacchini P, Mourmouras V, Miracco C. CD105/endoglin expression in Gorham disease of bone. J Clin Pathol 2009;62:163-167.
12. Cushing SL, Ishak G, Perkins JA, Rubinstein JT. Gorham-Stout syndrome of the petrous apex causing chronic cere-brospinal fluid leak. Otol Neurotol 2010;31:789-792.
13. Tempero RM, Hannibal M, Finn LS, Manning SC, Cun-ningham ML, Perkins JA. Lymphocytopenia in children with lymphatic malformations. Arch Otolaryngol Head Neck Surg 2006;132:93-97.
14. Perkins JA, Tempero RM, Hannibal MC, Manning SC Clinical outcomes in lymphocytopenic lymphatic mal-formation patients. Lymphat Res Biol 2007;5:169-174.
15. Hall AP, Westwood FR, Wadsworth PF. Review of the ef-fects of anti-angiogenic compounds on the epiphyseal growth plate. Toxicol Pathol 2006;34:131-147
16. Daley WP, Peters SB, Larsen M. Extracellular matrix dy-namics in development and regenerative medicine. J Cell Sci 2007;121:255-264.
17. Davis GE, Senger DR. Endothelial extracellular matrix: Bio-synthesis, remodeling, and functions during vascular mor-phogenesis and neovessel stabilization. Circ Res 2055;97: 1093-1107.
18. Maes C, Kobayashi T, Selig MK, Torrekens S, Roth SI, Mackem S, Carmeliet G, Kronenberg HM. Osteoblast pre-cursors, but not mature osteoblasts, move into developing and fractured bones along with invading blood vessels. Dev Cell 2010;19:329-344.
19. Wilting J, Becker J. Two endothelial cell lines derived from the somite. Anat Embryol (Berl) 2006;211:57-63.
20. Dalal S, Berry AM, Cullinane CJ, Mangham DC, Grimer R, Lewis IJ, Johnston C, Laurence V, Burchill SA. Vascular endothelial growth factor: A therapeutic target for tumors of the Ewing's sarcoma family. Clin Cancer Res 2055;11:2364-2378.
21. Ria R, Vacca A, Russo F, Cirulli T, Massaia M, Tosi P, Cavo M, Guidolin D, Ribatti D, Dammacco F. A VEGF-dependent autocrine loop mediates proliferation and capillarogenesis in bone marrow endothelial cells of patients with multiple myeloma. Thromb Haemost 2004;92:1438-1445. (Pubitemid 39642557)
22. Reddy K, Cao Y, Zhou Z, Yu L, Jia SF, Kleinerman ES. VEGF165 expression in the tumor microenvironment influ-ences the differentiation of bone marrow-derived pericytes that contribute to the Ewing's sarcoma vasculature. Angio-genesis 2008;11:257-267.
23. Grunewald M, Avraham I, Dor Y, Bachar-Lustig E, Itin A, Yung S, Chimenti S, Landsman L, Abramovitch R, Keshet E. VEGF-induced adult neovascularization: Recruitment, re-tention, and role of accessory cells. Cell 2006;124:175-189. (Pubitemid 43069318)
24. Stratman AN, Davis MJ, Davis GE. VEGF and FGF prime vascular tube morphogenesis and sprouting directed by hematopoietic stem cell cytokines. Blood 2011;117:3709-3719.
25. Tanaka Y, Abe M, Hiasa M, Oda A, Amou H, Nakano A, Takeuchi K, Kitazoe K, Kido S, Inoue D, Moriyama K, Ha-shimoto T, Ozaki S, Matsumoto T. Myeloma cell-osteoclast interaction enhances angiogenesis together with bone re-sorption: A role for vascular endothelial cell growth factor and osteopontin. Clin Cancer Res 2007;13:816-823. (Pubitemid 46340354)
26. Jacobsen KA, Al-Aql ZS, Wan C, Fitch JL, Stapleton SN, Mason ZD, Cole RM, Gilbert SR, Clemens TL, Morgan EF, Einhorn TA, Gerstenfeld LC. Bone formation during dis-traction osteogenesis is dependent on both VEGFR1 and VEGFR2 signaling. J Bone Miner Res 2008;23:596-609. (Pubitemid 351575014)
27. Orlandino M, Spreafico A, Bardelli M, Rocchigiani M, Sala-meh A, Nucciotti S, Capperucci C, Frediani B, Oliviero S, Vascular endothelial growth factor-D activates VEGFR-3 expressed in osteoblasts inducing their differentiation. J Biol Chem 2006;281:17961-17967 (Pubitemid 44035595)
28. Rissanen TT, Markkanen JE, Gruchala M, Heikura T, Pur-anen A, Kettunen MI, Kholova I, Kauppinen RA, Achen MG, Stacker SA, Alitalo K, Yla-Herttuala S. VEGF-D is the strongest angiogenic and lymphangiogenic effector among VEGFs delivered into skeletal muscle via adenoviruses. Circ Res 2003;92:1098-106. (Pubitemid 36665855)
29. Ji R.-C. Lymphatic endothelial cells, lymphangiogenesis, and extracellular matrix. Lymphat Res Biol 2006;4:83-100. (Pubitemid 44083659)
30. Lohela M, Bry M, Tammela T, Alitalo K. VEGFs and re-ceptors involved in angiogensis versus lymphangiogenesis. Curr Opin Cell Biol 2009;21:154-165.
31. Mishima K, Watabe T, Saito A, Yoshimatsu Y, Imaizumi N, Masui S, Hirashima M, Morisada T, Oike Y, Araie M, Niwa H, Kubo H, Suda T, Miyazono K. Prox1 induces lymphatic endothelial differentiation via integrin σ9 and other signal-ing cascades. Mol Biol Cell 2007;18:1421-1429. (Pubitemid 46626636)
32. Jussila L, Alitalo K. Vascular growth factors and lym-phangiogenesis. Physiol Rev 2002;82:673-700.
33. Salven P, Mustjoki S, Alitalo R, Alitalo K, Rafii S. VEGFR-3 and CD133 identify a population of CD34+ lymphatic/ vascular endothelial precursor cells. Blood 2003;101:168-172. (Pubitemid 36025904)
34. Ny A, Koch M, Vandevelde W, Schneider M, Fischer C, Diez-Juan A, Neven E, Geudens I, Maity S, Moons L, Plai-sance S, Lambrechts D, Carmeliet P, Dewerchin M. Role of VEGF-D and VEGFR-3 in developmental lymphangiogen-esis, a chemicogenetic study in Xenopus tadpoles. Blood 2008;112:1740-1749.
35. Cursiefen C, Chen L, Borges LP, Jackson D, Cao J, Radzie-jewski C, D'Amore PA. Dana MR, Wiegand SJ, Streilein JW. VEGF-A stimulates lymphangiogenesis and hemangiogen-esis in inflammatory neovascularization via macrophage recruitment. J Clin Invest 2004;113:1040-1050. (Pubitemid 38544126)
36. Kilic N, Oliveira-Ferrer L, Neshat 0, Vahid S, Irmak S, Obst-Pernberg K, Wurmbach J.-H, Loges S, Kilic E, Weil J, Lauke H, Tilki D, Singer BB, Ergun S. Lymphatic reprogramming of microvascular endothelial cells by CEA-related cell ad-hesion molecule-1 via interaction with VEGFR-3 and Prox1. Blood 2007;110:4223-4233. (Pubitemid 351377786)
37. Jell G, Kerjaschki D, Revell P, Al-Saffar N. Lymphangio-genesis in the bone-implant interface of orthopedic implants: Importance and consequence. J Biomed Mater Res 2006;77A: 119-127
38. Wilting J, Buttler K, Rossler J, Norgall S, Schweigerer L, Weich HA, Papoutsi M. Embryonic development and mal-formation of lymphatic vessels. Novartis Found Symp 2007; 283:220-227.
39. Kelly K, Hutchinson G, Nebenius-Oosthuizen D, Smith AJ, Bartsch JW, Horiuchi K, Rittger A, Manova K, Docherty AJ, Blobel CP. Metalloprotease- disintegrin ADAM8: Expression analysis and targeted deletion in mice. Dev Dyn 2005;232: 221-231. (Pubitemid 40070875)
40. Bennuru S, Nutman TB. Lymphangiogenesis and lymphatic remodeling induced by filarial parasites: Implications for pathogenesis. PLoS Pathog 2009;5:e1000688.
41. Marler JJ, Fishman SJ, Kilroy SM, Fang J, Upton J, Mulliken JB, Burrows PE, Zurakowski D, Folkman J, Moses MA. In-creased expression of urinary matrix metalloproteinases parallels the extent and activity of vascular anomalies. Pe-diatrics 2005;116:38-45.
42. Ortega N, Behonick D, Stickens D, Werb Z. How proteases regulate bone morphogenesis. Ann NY Acad Sci 2003;995: 109-116. (Pubitemid 36706618)
43. Lieu S, Hansen E, Dedini R, Behonick D, Werb Z, Miclau T, Marcucio R, Colnot C. Impaired remodeling phase of frac-ture repair in the absence of matrix metalloproteinase-2. Dis Model Mech 2011;4:203-211.
44. Cao X, Chen D. The BMP signaling and in vivo bone for-mation. Gene 2005;357:1-8. (Pubitemid 41267309)
45. Boyd NL, Dhara SK, Rekaya R, Godbey EA, Hasneen K, Rao RR, West FD III, Gerwe BA, Stice SL. BMP4 promotes for-mation of primitive vascular networks in human embryonic stem cell-derived embryoid bodies. Exp Biol Med 2007;232: 833-843. (Pubitemid 46827826)
46. Bressan M, Davis P, Timmer J, Herzlinger D, Mikawa T. Notochord-derived BMP antagonists inhibit endothelial cell generation and network formation. Dev Biol 2009;326:101-111.
47. Kloen P, DiPaola M, Borens O, Richmond J, Perino G, Helfet DL, Goumans MJ. BMP signaling components are expressed in human fracture callus. Bone 2003;33:362-371. (Pubitemid 37103253)
48. Lesiak M, Augusciak-Duma A, Szydlo A, Sieron A. Block-ing angiogenesis with peptides that inhibit the activity of procollagen C-endopeptidase. Pharmacol Rep 2009;61: 468-476.
49. Zhao M, Harris SE, Horn D, Geng Z, Nishimura R, Mundy G, Chen D. Bone morphogenetic protein receptor signaling is necessary for normal murine postnatal bone formation. J Cell Biol 2002;157:1049-1060. (Pubitemid 34839779)
50. Wigle JT, Oliver G. Prox1 function is required for the de-velopment of the murine lymphatic system. Cell 1999;98: 769-778. (Pubitemid 29446894)
51. Hong Y-K, Harvey N, Noh Y-H, Schacht V, Hirakawa S, Detmar M, Oliver G. Prox1 is a master control gene in the program specifying lymphatic endothelial cell fate. Dev Dyn 2002;225:351-357. (Pubitemid 35265813)
52. Yoshimatsu Y, Yamazaki T, Mihira H, Itoh T, Suehiro J, Yuki K, Harada K, Morikawa M, Iwata C, Minami T, Morishita Y, Kodama T, Miyazono K, Watabe T. Ets family members induce lymphangiogenesis through physical and functional interaction with Prox1. J Cell Sci 2011;124:2753-2762.
53. Harvey NL, Srinivasan RS, Dillard ME, Johnson NC, Witte MH, Boyd K, Sleeman MW, Oliver G. Lymphatic vascular defects promoted by Prox1 haploinsufficiency cause adult-onset obesity. Nat Genet 2005;37:1072-1081. (Pubitemid 41486659)
54. Maruyaama K, Asai J, Ii M, Thorne T, Losordo DW, D'Amore PA. Decreased macrophage number and activa-tion lead to reduced lymphatic vessel formation and con-tribute to impaired diabetic wound healing. Am J Pathol 2007;1270:1178-1191. (Pubitemid 47339326)
55. Murakami M, Zheng Y, Hirashima M, Suda T, Morita Y, Ooehara J, Ema H, Fong G-H, Shibuya M. VEGFR1 tyrosine kinase signaling promotes lymphangiogenesis as well as angiogenesis indirectly via macrophage recruitment. Arter-ioscler Thromb Vasc Biol 2008;28 658-664. (Pubitemid 351651323)
56. De Benedetti F. The impact of chronic inflammation on the growing skeleton: Lessons from interleukin-6 transgenic mice. Horm Res 2009;72:26-29.
57. Toben D, Schroeder I, El Khassawna T, Mehta M, Hoffmann JE, Frisch JT, Schell H, Lienau J, Serra A, Radbruch A, Duda GN. Fracture healing is accelerated in the absence of the adaptive immune system. J Bone Miner Res 2011;26:113-124.
58. Aikawa E, Nahrendorf M, Figueiredo JL, Swirski FK, Shtatland T, Kohler RH, Jaffer FA, Aikawa M, Weissleder R. Osteogenesis associates with inflammation in early-stage atherosclerosis evaluated by molecular imaging in vivo. Circulation 2007;116:2841-2850. (Pubitemid 350301146)
59. Rajamannan NM, Nealis TB, Subramaniam M, Pandya S, Stock SR, Ignatiev CI, Sebo TJ, Rosengart TK, Edwards WD, McCarthy PM, Bonow RO, Spelsberg TC. Calcified rheu-matic valve neoangiogenesis is associated with vascular endothelial growth factor expression and osteoblast-like bone formation. Circulation 2005;111:3296-3301. (Pubitemid 40875003)