AGMK CELL LINE;
ANIMAL CELL;
ANTIVIRAL ACTIVITY;
ARTICLE;
CONTROLLED STUDY;
DRUG CYTOTOXICITY;
DRUG SCREENING;
DRUG STRUCTURE;
DRUG SYNTHESIS;
ELEMENTAL ANALYSIS;
HUMAN ALPHAHERPESVIRUS 1;
IC50;
IN VITRO STUDY;
INFRARED SPECTROSCOPY;
MASS SPECTROMETRY;
NONHUMAN;
POLYMERIZATION;
PROTON NUCLEAR MAGNETIC RESONANCE;
Design, synthesis and biological evaluation of novel pyridine derivatives as anticancer agents and phosphodiesterase 3 inhibitors
Abadi AH, Ibrahim TM, Abouzid KM, Lehmann J, Tinsley HN, Gary BD, Piazza GA (2009) Design, synthesis and biological evaluation of novel pyridine derivatives as anticancer agents and phosphodiesterase 3 inhibitors. Bioorg Med Chem 17:5974–5982
Novel substituted and fused pyrrolizine derivatives: Synthesis, anti-inflammatory and ulcerogenecity studies
Abbas SE, Awadallah FM, Ibrahim NA, Gouda AM (2010) Novel substituted and fused pyrrolizine derivatives: synthesis, anti-inflammatory and ulcerogenecity studies. Eur J Med Chem 45: 482–491
Differential activities of 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine derivatives against different human immunodeficiency virus type 1 mutant strains
Balzarini J, Baba M, De Clerq E (1995) Differential activities of 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine derivatives against different human immunodeficiency virus type 1 mutant strains. Antimicrob Agents Chemother 39:998–1002
Synthesis, anti HSV-1 and cytotoxic activities of some new pyrazole- and isoxazole-based heterocycles
Dawood KM, Abdel-Gawad H, Mohamed HA, Badria FA (2010) Synthesis, anti HSV-1 and cytotoxic activities of some new pyrazole- and isoxazole-based heterocycles. Med Chem Res 20: 912–919
Synthesis, DNA-binding, and antiviral activity of certain pyrazolo[3,4-d]pyrimidine derivatives
El-Bendary ER, Badria FA (2000) Synthesis, DNA-binding, and antiviral activity of certain pyrazolo[3,4-d]pyrimidine derivatives. Arch. Pharm. (Weinheim) 333:99–103
Synthesis and biological evaluation of certain a,b-unsaturated ketones and their corresponding fused pyrimidines as antiviral and antitumer agents
El-Subbagh HI, Abu-Zaid SM, Mahran MA, Abdulrahman M, Badria FA (2000) Synthesis and biological evaluation of certain a,b-unsaturated ketones and their corresponding fused pyrimidines as antiviral and antitumer agents. J Med Chem 43:2915–2921
Synthesis and antiviral activity of new pyrazole and thiazole derivatives
El-Subbagh OI, Baraka MM, Ibrahim SM, Pannecouque C, Andrei G, Snoeck R, Balzarini J, Rashad AA (2009) Synthesis and antiviral activity of new pyrazole and thiazole derivatives. Eur J Med Chem 44:3746–3753
Novel 1,5-diphenylpyrazole non-nucleoside HIV-1 reverse transcriptase inhibitors with enhanced activity versus the delavirdine-resistant P236L mutant: Lead identification and SAR of 3- and 4-substituted derivatives
Genin MJ, Biles C, Keiser BJ, Poppe SM, Swaney SM, Tarpley WG, Yagi Y, Romero DL (2000) Novel 1,5-diphenylpyrazole non-nucleoside HIV-1 reverse transcriptase inhibitors with enhanced activity versus the delavirdine-resistant P236L mutant: lead identification and SAR of 3- and 4-substituted derivatives. J Med Chem 43:1034–1040
Cytotoxicity and utility of 1-indanone in the synthesis of some new heterocycles
Hegazi B, Mohamed HA, Dawood KM, Badria FA (2010) Cytotoxicity and utility of 1-indanone in the synthesis of some new heterocycles. Chem Pharm Bull 58:479–483
Synthesis and biological evaluation of some novel triazolopyrimidines as antimicrobial, antiviral and cytotoxic agents
Maarouf AR, Badria FA (2005) Synthesis and biological evaluation of some novel triazolopyrimidines as antimicrobial, antiviral and cytotoxic agents. MJPS 21:42–58
Synthesis and antiviral activity of novel pyrazole derivatives containing oxime esters group
Ouyang G, Chen Z, Cai XJ, Song BA, Bhadury PS, Yang S, Jin Xue LHW, Hu DY, Zeng S (2008) Synthesis and antiviral activity of novel pyrazole derivatives containing oxime esters group. Bioorg Med Chem 16:9699–9707
Antiviral activity of Win 41258-3, a pyrazole compound, against herpes simplex in mouse genital infection and in guinea pig skin infection
Pancic F, Steinberg BA, Diana GD, Carabateas PM, Gorman WG, Came PE (1981) Antiviral activity of Win 41258-3, a pyrazole compound, against herpes simplex in mouse genital infection and in guinea pig skin infection. Antimicrob Agents Chemother 19:470–476
New non-nucleoside reverse transcriptase inhibitors (NNRTIs) in development for the treatment of HIV infections
Pauwels R (2004) New non-nucleoside reverse transcriptase inhibitors (NNRTIs) in development for the treatment of HIV infections. Curr Opin Pharmacol 4:437–446
Preparation of 1,1-disubstituted cycloalkyl derivative as factor Xa inhibitors for treating a thromboembolic disorder. PCT Int Appl WO 03 99, 276
Qiao JX, Pinto DJ, Orwat MJ, Han W, Friedrich SR (2004) Preparation of 1,1-disubstituted cycloalkyl derivative as factor Xa inhibitors for treating a thromboembolic disorder. PCT Int Appl WO 03 99, 276, Chemical Abstracts 140, 16722g
Polysubstitut-ed pyrazoles, part 5. Synthesis of new 1-(4-chlorophenyl)-4-hydroxy-1H-pyrazole-3-carboxylic acid hydrazide analogs and some derived ring systems. A novel class of potential antitumor and anti-HCV agents
Rostom SAF, Shalaby MA, El-Demellawy MA (2003) Polysubstitut-ed pyrazoles, part 5. Synthesis of new 1-(4-chlorophenyl)-4-hydroxy-1H-pyrazole-3-carboxylic acid hydrazide analogs and some derived ring systems. A novel class of potential antitumor and anti-HCV agents. Eur J Med Chem 38:959–974
Efficient synthesis and utilization of phenyl-substituted heteroaromatic carboxylic acids as aryl diketo acid isosteres in the design of novel HIV-1 integrase inhibitors
Zeng L, Zhang H, Wang Y, Sanchez T, Zheng Y, Neamati N, Long Y (2008) Efficient synthesis and utilization of phenyl-substituted heteroaromatic carboxylic acids as aryl diketo acid isosteres in the design of novel HIV-1 integrase inhibitors. Bioorg Med Chem Lett 18:4521–4524
