Thymidine kinase 2 deficiency-induced mitochondrial dna depletion causes abnormal development of adipose tissues and adipokine levels in mice

PLoS ONE

Volumn 6, Issue 12, 2011, Pages

  Villarroya, Joan ^a,b,c   Dorado, Beatriz ^d   Vilà, Maya R ^e   Garcia Arumí, Elena ^e,f   Domingo, Pere ^b   Giralt, Marta ^a,c   Hirano, Michio ^d   Villarroya, Francesc ^a,c  

^a UNIVERSITY OF BARCELONA   (Spain)

^b HOSPITAL DE LA SANTA CREU I SANT PAU   (Spain)

^c Instituto de Salud Carlos III   (Spain)

^d Department of Medicine   (United States)

^e HOSPITAL UNIVERSITARI VALL D HEBRON   (Spain)

^f INSTITUTO DE SALUD CARLOS III   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPOCYTOKINE; CASPASE 9; CYTOCHROME C OXIDASE; GLUTATHIONE PEROXIDASE; GROWTH HORMONE INDUCIBLE MEMBRANE PROTEIN; INITIATION FACTOR 2; INITIATION FACTOR 3; LEPTIN; MANGANESE SUPEROXIDE DISMUTASE; MEMBRANE PROTEIN; MESSENGER RNA; MITOCHONDRIAL DNA; MITOCHONDRIAL INNER MEMBRANE PROTEIN; MITOCHONDRIAL TRANSCRIPTION FACTOR A; MITOCHONDRIAL TRANSCRIPTION FACTOR B; MITOFUSIN 2; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); RESISTIN; THYMIDINE KINASE; THYMIDINE KINASE 2; UBIQUINOL CYTOCHROME C REDUCTASE; UNCLASSIFIED DRUG; UNCOUPLING PROTEIN 2; UNCOUPLING PROTEIN 3; PRIMER DNA;

ADIPOCYTE; ADIPOGENESIS; ADIPOSE TISSUE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BROWN ADIPOSE TISSUE; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ELECTRON MICROSCOPY; ENZYME ACTIVITY; ENZYME DEFICIENCY; GENE EXPRESSION; HYPOTROPHY; LIPID STORAGE; MITOCHONDRIAL DNA DEPLETION; MITOCHONDRIAL RESPIRATION; MOUSE; NEUROMUSCULAR DISEASE; NONHUMAN; OXIDATIVE PHOSPHORYLATION; THERMOGENESIS; WHITE ADIPOSE TISSUE; ANIMAL; ELECTRON TRANSPORT; GENETICS; METABOLISM; MITOCHONDRION; MUTATION; NUCLEOTIDE SEQUENCE; PATHOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSMISSION ELECTRON MICROSCOPY; WESTERN BLOTTING;

ADIPOKINES; ADIPOSE TISSUE; ANIMALS; BASE SEQUENCE; BLOTTING, WESTERN; DNA PRIMERS; DNA, MITOCHONDRIAL; ELECTRON TRANSPORT; MICE; MICROSCOPY, ELECTRON, TRANSMISSION; MITOCHONDRIA; MUTATION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; THYMIDINE KINASE;

EID: 84455190873     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0029691     Document Type: Article

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