The inhibitory effects of perfluoroalkyl substances on human and rat 11β-hydroxysteroid dehydrogenase 1

Chemico-Biological Interactions

Volumn 195, Issue 2, 2012, Pages 114-118

  Ye, Leping ^a,b   Zhao, Binghai ^c   Cai, Xiao Hong ^a   Chu, Yanhui ^c   Li, Changchong ^a   Ge, Ren Shan ^a,b  

^a WENZHOU MEDICAL UNIVERSITY   (China)

^b POPULATION COUNCIL   (United States)

^c Mu Dan Jiang Medical College   (China)

Author keywords

11 Hydroxysteroid dehydrogenase 1; Enzyme inhibition; PFOA; PFOS

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE 1; PERFLUORO COMPOUND; PERFLUOROALKYL SUBSTANCE; PERFLUOROOCTANESULFONIC ACID; PERFLUOROOCTANOIC ACID; POTASSIUM PERFLUOROBUTANESULFONATE; POTASSIUM PERFLUOROHEXANESULFONATE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN TISSUE; IC 50; LIVER; LUNG; MALE; NEWBORN; NONHUMAN; RAT;

11-BETA-HYDROXYSTEROID DEHYDROGENASES; ALKANESULFONATES; ALKANESULFONIC ACIDS; ANIMALS; BINDING, COMPETITIVE; ENZYME ACTIVATION; ENZYME INHIBITORS; FLUOROCARBONS; HUMANS; INHIBITORY CONCENTRATION 50; MALE; OCTANOIC ACIDS; RATS; SULFONIC ACIDS;

RATTUS; RODENTIA;

EID: 84455170934     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2011.11.007     Document Type: Article

References (28)

1. A.A. Jensen, and H. Leffers Emerging endocrine disrupters: perfluoroalkylated substances Int. J. Androl. 31 2 2008 161 169 (Pubitemid 351341398)
2. J.P. Giesy, and K. Kannan Perfluorochemical surfactants in the environment Environ. Sci. Technol. 36 7 2002 146A 152A (Pubitemid 34279825)
3. C. Lau, K. Anitole, C. Hodes, D. Lai, A. Pfahles-Hutchens, and J. Seed Perfluoroalkyl acids: a review of monitoring and toxicological findings Toxicol. Sci. 99 2 2007 366 394 (Pubitemid 351753056)
4. K.S. Betts Perfluoroalkyl acids: what is the evidence telling us? Environ. Health Perspect. 115 5 2007 A250 256
5. B.J. Apelberg, F.R. Witter, J.B. Herbstman, A.M. Calafat, R.U. Halden, L.L. Needham, and L.R. Goldman Cord serum concentrations of perfluorooctane sulfonate (PFOS) and perfluorooctanoate (PFOA) in relation to weight and size at birth Environ. Health Perspect. 115 11 2007 1670 1676
6. J.L. Butenhoff, D.J. Ehresman, S.C. Chang, G.A. Parker, and D.G. Stump Gestational and lactational exposure to potassium perfluorooctanesulfonate (K + PFOS) in rats: developmental neurotoxicity Reprod. Toxicol. 27 3-4 2009 319 330
7. L. Cui, Q.F. Zhou, C.Y. Liao, J.J. Fu, and G.B. Jiang Studies on the toxicological effects of PFOA and PFOS on rats using histological observation and chemical analysis Arch. Environ. Contam. Toxicol. 56 2 2009 338 349
8. M.B. Rosen, J.E. Schmid, K.P. Das, C.R. Wood, R.D. Zehr, and C. Lau Gene expression profiling in the liver and lung of perfluorooctane sulfonate-exposed mouse fetuses: comparison to changes induced by exposure to perfluorooctanoic acid Reprod. Toxicol. 27 3-4 2009 278 288
9. D. Yahia, C. Tsukuba, M. Yoshida, I. Sato, and S. Tsuda Neonatal death of mice treated with perfluorooctane sulfonate J. Toxicol. Sci. 33 2 2008 219 226 (Pubitemid 351872363)
10. R.C. Grasty, J.A. Bjork, K.B. Wallace, D.C. Wolf, C.S. Lau, and J.M. Rogers Effects of prenatal perfluorooctane sulfonate (PFOS) exposure on lung maturation in the perinatal rat Birth Defects Res. B Dev. Reprod. Toxicol. 74 5 2005 405 416 (Pubitemid 41579584)
11. B. Zhao, Q.Q. Lian, Y. Chu, D.O. Hardy, X.K. Li, and R.S. Ge The inhibition of human and rat 11 beta-hydroxysteroid dehydrogenase 2 by perfluoroalkylated substances J. Steroid. Biochem. Mol. Biol. 125 1-2 2011 143 147
12. R.J. Bolt, M.M. van Weissenbruch, and H.N. Lafeber H.A. Delemarre-van de Waal, Glucocorticoids and lung development in the fetus and preterm infant Pediatr. Pulmonol. 32 1 2001 76 91
13. S. Suzuki, H. Tsubochi, A. Darnel, T. Suzuki, H. Sasano, Z.S. Krozowski, and T. Kondo Expression of 11 beta-hydroxysteroid dehydrogenase type 1 in alveolar epithelial cells in rats Endocr. J. 50 4 2003 445 451 (Pubitemid 37129038)
14. S. Hundertmark, V. Ragosch, B. Schein, H. Buhler, M. Fromm, U. Lorenz, and H.K. Weitzel 11-Beta-hydroxysteroid dehydrogenase of rat lung: enzyme kinetic, oxidase-reductase ratio, electrolyte and trace element dependence Enzyme Protein 47 2 1993 83 91 (Pubitemid 24054040)
15. T.E. Nicholas, and M.A. Lugg The physiological significance of 11 beta-hydroxysteroid dehydrogenase in the rat lung J. Steroid Biochem. 17 1 1982 113 118 (Pubitemid 13228693)
16. S. Hundertmark, A. Dill, A. Ebert, B. Zimmermann, Y.V. Kotelevtsev, J.J. Mullins, and J.R. Seckl Foetal lung maturation in 11 beta-hydroxysteroid dehydrogenase type 1 knockout mice Horm. Metab. Res. 34 10 2002 545 549 (Pubitemid 35370362)
17. V. Lakshmi, and C. Monder Extraction of 11 beta-hydroxysteroid dehydrogenase from rat liver microsomes by detergents J Steroid Biochem 22 3 1985 331 340 (Pubitemid 15089135)
18. R.S. Ge, H.B. Gao, V.L. Nacharaju, G.L. Gunsalus, and M.P. Hardy Identification of a kinetically distinct activity of 11 beta-hydroxysteroid dehydrogenase in rat Leydig cells Endocrinology 138 6 1997 2435 2442 (Pubitemid 27215247)
19. C. Frick, A.G. Atanasov, P. Arnold, J. Ozols, and A. Odermatt Appropriate function of 11 beta-hydroxysteroid dehydrogenase type 1 in the endoplasmic reticulum lumen is dependent on its N-terminal region sharing similar topological determinants with 50-kDa esterase J. Biol. Chem. 279 30 2004 31131 31138 (Pubitemid 39037775)
20. S. Arampatzis, B. Kadereit, D. Schuster, Z. Balazs, R.A. Schweizer, F.J. Frey, T. Langer, and A. Odermatt Comparative enzymology of 11 beta-hydroxysteroid dehydrogenase type 1 from six species J. Mol. Endocrinol. 35 1 2005 89 101 (Pubitemid 41167628)
21. W. Hu, P.D. Jones, W. DeCoen, L. King, P. Fraker, J. Newsted, and J.P. Giesy Alterations in cell membrane properties caused by perfluorinated compounds Comp. Biochem. Physiol. C: Toxicol. Pharmacol. 135 1 2003 77 88 (Pubitemid 36644994)
22. S.A. Rooney, S.L. Young, and C.R. Mendelson Molecular and cellular processing of lung surfactant FASEB J. 8 12 1994 957 967 (Pubitemid 24286859)
23. C.R. Mendelson, E. Gao, J. Li, P.P. Young, L.F. Michael, and J.L. Alcorn Regulation of expression of surfactant protein-A Biochim. Biophys. Acta 1408 2-3 1998 132 149 (Pubitemid 28517862)
24. A.K. Agarwal, F.M. Rogerson, T. Mune, and P.C. White Analysis of the human gene encoding the kidney isozyme of 11 beta-hydroxysteroid dehydrogenase J. Steroid Biochem. Mol. Biol. 55 5-6 1995 473 479 (Pubitemid 26022381)
25. Y. Jin, N. Saito, K.H. Harada, K. Inoue, and A. Koizumi Historical trends in human serum levels of perfluorooctanoate and perfluorooctane sulfonate in Shenyang, China Tohoku J. Exp. Med. 212 1 2007 63 70 (Pubitemid 46711727)
26. N. Yabaluri, and M.D. Bashyam Hormonal regulation of gluconeogenic gene transcription in the liver J. Biosci. 35 3 2010 473 484
27. G.W. Olsen, D.C. Mair, T.R. Church, M.E. Ellefson, W.K. Reagen, T.M. Boyd, R.M. Herron, Z. Medhdizadehkashi, J.B. Nobiletti, J.A. Rios, J.L. Butenhoff, and L.R. Zobel Decline in perfluorooctanesulfonate and other polyfluoroalkyl chemicals in American Red Cross adult blood donors, 2000-2006 Environ. Sci. Technol. 42 13 2008 4989 4995 (Pubitemid 351956443)
28. K. Ward, DuPont finds high C8 in Chinese workers, The Charleston Gazette, 2008.