Increased P-glycoprotein expression in mitochondria is related to acquired multidrug resistance in human hepatoma cells depleted of mitochondrial DNA

International Journal of Oncology

Volumn 40, Issue 1, 2012, Pages 109-118

  Ling, Xianlong ^a   He, Yuqi ^a   Zhang, Guoqiao ^a   Zhou, Yuan ^a   Yan, Bin ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Mitochondrial DNA; Multidrug resistance; P glycoprotein; Tumor

Indexed keywords

CISPLATIN; DOXORUBICIN; ETHIDIUM BROMIDE; FLUOROURIDINE; GLYCOPROTEIN P; MITOCHONDRIAL DNA; MITOCHONDRIAL PROTEIN; VINCRISTINE;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; CYBRID; CYTOSOL; GENE OVEREXPRESSION; HEPATOMA CELL; HUMAN; HUMAN TISSUE; MULTIDRUG RESISTANCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BLOTTING, WESTERN; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; DNA, MITOCHONDRIAL; DOXORUBICIN; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; FLOW CYTOMETRY; HUMANS; LIVER NEOPLASMS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICROSCOPY, FLUORESCENCE; MITOCHONDRIA, LIVER; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; P-GLYCOPROTEIN; PROTO-ONCOGENE PROTEINS C-BCL-2; REACTIVE OXYGEN SPECIES;

EID: 84455163094     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2011.1181     Document Type: Article

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