Selective, cytotoxic organoruthenium(II) full-sandwich complexes: A structural, computational and in vitro biological study

Chemistry - An Asian Journal

Volumn 7, Issue 1, 2012, Pages 112-121

  Loughrey, Bradley T ^a   Cunning, Benjamin V ^a   Healy, Peter C ^a   Brown, Christopher L ^a   Parsons, Peter G ^b   Williams, Michael L ^a  

^a GRIFFITH UNIVERSITY   (Australia)

^b QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

Author keywords

arenes; cancer; cyclopentadienyl ligands; organometallic; ruthenium

Indexed keywords

ARENES; BIOLOGICAL STUDIES; CANCER; CATIONIC CHARGES; COMPUTATIONAL EXPERIMENT; CYCLOPENTADIENYL LIGANDS; CYCLOPENTADIENYLS; CYTOTOXIC; DIVERSE RANGE; ELECTROSPRAY MASS SPECTROMETRY; ELECTROSTATIC POTENTIALS; GROWTH INHIBITOR; HARTREE-FOCK THEORY; IN-VITRO; IR AND NMR SPECTROSCOPY; MACROPHAGE CELL LINE; NORMAL HUMAN FIBROBLAST; PERTURBATION THEORY; SECOND ORDERS; TUMORIGENIC CELLS; X-RAY STRUCTURAL DETERMINATION;

CARBON DIOXIDE; CELL CULTURE; CYTOTOXICITY; DYES; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; ORGANOMETALLICS; PERTURBATION TECHNIQUES; RUTHENIUM;

RUTHENIUM COMPOUNDS;

ANTINEOPLASTIC AGENT; ORGANOMETALLIC COMPOUND; RUTHENIUM;

ANIMAL; ARTICLE; CELL PROLIFERATION; CHEMICAL STRUCTURE; CHEMISTRY; CYTOLOGY; DRUG EFFECT; DRUG SCREENING; FIBROBLAST; HUMAN; MACROPHAGE; MOUSE; QUANTUM THEORY; STRUCTURE ACTIVITY RELATION; SYNTHESIS; TUMOR CELL CULTURE; X RAY CRYSTALLOGRAPHY;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL PROLIFERATION; CRYSTALLOGRAPHY, X-RAY; DRUG SCREENING ASSAYS, ANTITUMOR; FIBROBLASTS; HUMANS; MACROPHAGES; MICE; MODELS, MOLECULAR; MOLECULAR STRUCTURE; ORGANOMETALLIC COMPOUNDS; QUANTUM THEORY; RUTHENIUM; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 84255205585     PISSN: 18614728     EISSN: 1861471X     Source Type: Journal    
DOI: 10.1002/asia.201100637     Document Type: Article

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