Characterization of γ-carboxylated tryptic peptides by collision-induced dissociation and electron transfer dissociation mass spectrometry

European Journal of Mass Spectrometry

Volumn 17, Issue 5, 2011, Pages 497-506

  Ramström, Margareta ^a   Sandberg, Helena ^a  

^a Octapharma AB   (Sweden)

Author keywords

CID; ETD; Mass spectrometry; MS MS; Protein C; hydroxyaspartic acid; carboxyglutamic acid

Indexed keywords

AMINO ACIDS; CARBOXYLATION; DISSOCIATION; DRUG PRODUCTS; ELECTRON TRANSITIONS; GLYCOPROTEINS; ION CHROMATOGRAPHY; MASS SPECTROMETRY;

AMINO ACID RESIDUES; BIOPHARMACEUTICAL INDUSTRY; CARBOXYGLUTAMIC ACID; COLLISION INDUCED DISSOCIATION; ELECTRON-TRANSFER DISSOCIATION; MS/MS; PEPTIDE SEQUENCING; POST-TRANSLATIONAL MODIFICATIONS;

PEPTIDES;

EID: 84255201559     PISSN: 14690667     EISSN: None     Source Type: Journal    
DOI: 10.1255/ejms.1149     Document Type: Article

References (29)

1. G. Walsh and R. Jefferis, "Post-translational modifications in the context of therapeutic proteins", Nat. Biotechnol. 24, 1241 (2006). doi: 10.1038/nbt1252 (Pubitemid 44564769)
2. M.R. Larsen, M.B. Trelle, T.E. Thingholm and O.N. Jensen, "Analysis of posttranslational modifications of proteins by tandem mass spectrometry", Biotechniques 40, 790 (2006). doi: 10.2144/000112201 (Pubitemid 46534920)
3. L. Sleno and D.A. Volmer, "Ion activation methods for tandem mass spectrometry", J. Mass Spectrom. 39, 1091 (2004). doi: 10.1002/jms.703 (Pubitemid 39409895)
4. R.A. Zubarev, N.L. Kelleher and F.W. McLafferty, "Electron capture dissociation of multiply charged protein cations. A nonergodic process", J. Am. Chem. Soc. 120, 3265 (1998). doi: 10.1021/ja973478k
5. J.E. Syka, J.J. Coon, M.J. Schroeder, J. Shabanowitz and D.F. Hunt, "Peptide and protein sequence analysis by electron transfer dissociation mass spectrometry", Proc. Natl. Acad. Sci. USA 101, 9528 (2004). doi: 10.1073/pnas.0402700101 (Pubitemid 38869270)
6. R.G. Hartmer, D.A. Kaplan, C.R. Gebhardt, T. Ledertheil and A. Brekenfeld, "Multiple ion/ion reaction in the 3D ion trap: Selective reagent anion production for ETD and PTR from a single compound", Int. J. Mass Spectrom. 276, 82 (2008). doi: 10.1016/j.ijms.2008.05.002
7. P. Roepstorff and J. Fohlman, "Proposal for a common nomenclature for sequence ions in mass spectra of peptides", Biomed. Mass Spectrom. 11, 601 (1984). doi: 10.1002/bms.1200111109
8. L.M. Mikesh, B. Ueberheide, A. Chi, J.J. Coon, J.E. Syka, J. Shabanowitz and D.F. Hunt, "The utility of ETD mass spectrometry in proteomic analysis", Biochim. Biophys. Acta 1764, 1811 (2006). doi: 10.1016/j.bbapap. 2006.10.003
9. J. Wiesner, T. Premsler and A. Sickmann, "Application of electron transfer dissociation (ETD) for the analysis of posttranslational modifications", Proteomics 8, 4466 (2008). doi: 10.1002/pmic.200800329
10. A. Chi, C. Huttenhower, L.Y. Geer, J.J. Coon, J.E. Syka, D.L. Bai, J. Shabanowitz, D.J. Burke, O.G. Troyanskaya and D.F. Hunt, "Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry", Proc. Natl. Acad. Sci. USA 104, 2193 (2007). doi: 10.1073/pnas.0607084104 (Pubitemid 46391374)
11. Z. Darula, R.J. Chalkley, P. Baker, A.L. Burlingame and K.F. Medzihradszky, "Mass spectrometric analysis, automated identification and complete annotation of O-linked glycopeptides", Eur. J. Mass Spectrom. 16, 421 (2010). doi: 10.1255/ejms.1028
12. I. Perdivara, R. Petrovich, B. Allinquant, L.J. Deterding, K.B. Tomer and M. Przybylski, "Elucidation of O-glycosylation structures of the beta-amyloid precursor protein by liquid chromatography-mass spectrometry using electron transfer dissociation and collision induced dissociation", J. Proteome. Res. 8, 631 (2009). doi: 10.1021/pr800758g
13. F. Sobott, S.J. Watt, J. Smith, M.J. Edelmann, H.B. Kramer and B.M. Kessler, "Comparison of CID versus ETD based MS/MS fragmentation for the analysis of protein ubiquitination", J. Am. Soc. Mass Spectrom. 20, 1652 (2009). doi: 10.1016/j.jasms.2009.04.023
14. R. Srikanth, J. Wilson and R.W. Vachet, "Correct identification of oxidized histidine residues using electron-transfer dissociation", J. Mass Spectrom. 44, 755 (2009). doi: 10.1002/jms.1552
15. D.M. Good, M. Wirtala, G.C. McAlister and J.J. Coon, "Performance characteristics of electron transfer dissociation mass spectrometry", Mol. Cell Proteomics 6, 1942 (2007). doi: 10.1074/mcp.M700073-MCP200 (Pubitemid 350213868)
16. S. Gillis, B.C. Furie, B. Furie, H. Patel, M.C. Huberty, M. Switzer, W.B. Foster, H.A. Scoble and M.D. Bond, "Gamma-carboxyglutamic acids 36 and 40 do not contribute to human factor IX function", Protein Sci. 6, 185 (1997). doi: 10.1002/pro.5560060121
17. M. Napolitano, G. Mariani and M. Lapecorella, "Hereditary combined deficiency of the vitamin K-dependent clotting factors", Orphanet. J. Rare. Dis. 5, 21 (2010). doi: 10.1186/1750-1172-5-21
18. K. Hansson and J. Stenflo, "Post-translational modifications in proteins involved in blood coagulation", J. Thromb. Haemost. 3, 2633 (2005). doi: 10.1111/j.1538-7836.2005.01478.x (Pubitemid 41819790)
19. K.E. Van Cott and A. Oomen, "Characterization of gamma-carboxyglutamate-containing peptides using CID MS-MS and discovery of a new site of gamma-carboxylation in factor IX", Poster presentation, ASMS 2007.
20. N.L. Kelleher, R.A. Zubarev, K. Bush, B. Furie, B.C. Furie, F.W. McLafferty and C.T. Walsh, "Localization of labile posttranslational modifications by electron capture dissociation: the case of gamma- carboxyglutamic acid", Anal. Chem. 71, 4250 (1999). doi: 10.1021/ac990684x (Pubitemid 29466405)
21. H. Niiranen, B.A. Budnik, R.A. Zubarev, S. Auriola and S. Lapinjoki, "High-performance liquid chromatography- mass spectrometry and electron-capture dissociation tandem mass spectrometry of osteocalcin. Determination of gamma-carboxyglutamic acid residues", J. Chromatogr. A 962, 95 (2002). doi: 10.1016/S0021-9673(02)00451-X (Pubitemid 34655745)
22. D.C. Foster, S. Yoshitake and E.W. Davie, "The nucleotide sequence of the gene for human protein C", Proc. Natl. Acad. Sci. USA 82, 4673 (1985). doi: 10.1073/pnas.82.14.4673 (Pubitemid 16239625)
23. W. Kisiel, "Human plasma protein C: isolation, characterization and mechanism of activation by alpha-thrombin", J. Clin. Invest. 64, 761 (1979). doi: 10.1172/JCI109521
24. S. Ruggeberg, P. Horn, X. Li, P. Vajkoczy and T. Franz, "Detection of a gamma-carboxy-glutamate as novel post-translational modification of human transthyretin", Protein Pept. Lett. 15, 43 (2008). doi: 10.2174/092986608783330297 (Pubitemid 351206475)
25. M. Bond, M. Jankowski, H. Patel, S. Karnik, A. Strang, B. Xu, J. Rouse, S. Koza, B. Letwin, J. Steckert, G. Amphlett and H. Scoble, "Biochemical characterization of recombinant factor IX", Semin. Hematol. 35, 11 (1998).
26. S.A. Carr, P.V. Hauschka and K. Biemann, "Gas chromatographic mass spectrometric sequence determination of osteocalcin, a gamma-carboxyglutamic acid-containing protein from chicken bone", J. Biol. Chem. 256, 9944 (1981).
27. D.L. Coutu, J.H. Wu, A. Monette, G.E. Rivard, M.D. Blostein and J. Galipeau, "Periostin, a member of a novel family of vitamin K-dependent proteins, is expressed by mesenchymal stromal cells", J. Biol. Chem. 283, 17991 (2008). doi: 10.1074/jbc.M708029200
28. G.C. McAlister, D. Phanstiel, D.M. Good, W.T. Berggren and J.J. Coon, "Implementation of electron-transfer dissociation on a hybrid linear ion trap-orbitrap mass spectrometer", Anal. Chem. 79, 3525 (2007). doi: 10.1021/ac070020k (Pubitemid 46799044)
29. R.G. Hartmer, D.A. Kaplan, C. Stoermer, M. Lubeck and M.A. Park, "Data-dependent electron transfer dissociation of large peptides and medium size proteins in a QTOF instrument on a liquid chromatography timescale", Rapid Commun. Mass Spectrom. 23, 2273 (2009). doi: 10.1002/rcm.4145