Calcium homeostasis in vascular smooth muscle cells is altered in type 2 diabetes by BCL-2 protein modulation of insP 3R calcium release channels

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 302, Issue 1, 2012, Pages

  Velmurugan, Gopal V ^a   White, Carl ^a  

^a ROSALIND FRANKLIN UNIVERSITY OF MEDICINE AND SCIENCE   (United States)

Author keywords

ABT 737; BCL XL; DB DB mice; Inositol 1,4,5 trisphosphate receptor; Pressure myography

Indexed keywords

4 [4 (4' CHLORO 2 BIPHENYLYLMETHYL) 1 PIPERAZINYL] N [4 [3 DIMETHYLAMINO 1 (PHENYLTHIOMETHYL)PROPYLAMINO] 3 NITROBENZENESULFONYL]BENZAMIDE; INOSITOL 1,4,5 TRISPHOSPHATE RECEPTOR; PROTEIN BCL 2; PROTEIN BCL XL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CONTROLLED STUDY; MALE; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SARCOPLASMIC RETICULUM; SMOOTH MUSCLE CONTRACTILITY; STEADY STATE; VASCULAR SMOOTH MUSCLE;

ANIMALS; AORTA, THORACIC; BCL-X PROTEIN; BIPHENYL COMPOUNDS; BLOOD GLUCOSE; CALCIUM; CALCIUM SIGNALING; CELLS, CULTURED; DIABETES MELLITUS, TYPE 2; DIABETIC ANGIOPATHIES; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; HOMEOSTASIS; INOSITOL 1,4,5-TRISPHOSPHATE; INOSITOL 1,4,5-TRISPHOSPHATE RECEPTORS; MALE; MICE; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; NITROPHENOLS; PIPERAZINES; PROTO-ONCOGENE PROTEINS C-BCL-2; SARCOPLASMIC RETICULUM; SULFONAMIDES; TIME FACTORS; UP-REGULATION; VASOCONSTRICTION;

EID: 84255171053     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00218.2011     Document Type: Article

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