Human vascular smooth muscle cells from diabetic patients are resistant to induced apoptosis due to high Bcl-2 expression

Diabetes

Volumn 55, Issue 5, 2006, Pages 1243-1251

  Ruiz, Emilio ^a   Gordillo Moscoso, Antonio ^a   Padilla, Eugenia ^a   Redondo, Santiago ^a   Rodriguez, Enrique ^b   Reguillo, Fernando ^b   Briones, Ana M ^c   Van Breemen, Cornelis ^d   Okon, Elena ^d   Tejerina, Teresa ^a  

^a SCHOOL OF MEDICINE   (Spain)

^b HOSPITAL CLÍNICO SAN CARLOS   (Spain)

^c UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^d UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

CRP, C reactive protein; ERK1 2, extracellular signal related kinases 1 and 2; IMA, internal mammary artery; TBS T, Tris buffered saline with tween; VSMC, vascular smooth muscle cell

Indexed keywords

7BETA HYDROXYCHOLESTEROL; ANTIDIABETIC AGENT; C REACTIVE PROTEIN; CASPASE 3; COLLAGEN; DNA FRAGMENT; ELASTIN; GLUCOSE; HYDROGEN PEROXIDE; INSULIN; PROTEIN BCL 2; PROTEIN BCL XL; SMALL INTERFERING RNA; MANNITOL;

ADULT; AGED; APOPTOSIS; ARTICLE; CELL CULTURE; CELL ISOLATION; CELL PROLIFERATION; CONTROLLED STUDY; CORONARY ARTERY BYPASS GRAFT; DIABETES MELLITUS; DOSE RESPONSE; DRUG EFFECT; GENE OVEREXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; IMMUNOFLUORESCENCE TEST; INTERNAL MAMMARY ARTERY; ISOLATED ARTERY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN EXPRESSION; VASCULAR SMOOTH MUSCLE; WESTERN BLOTTING; CORONARY BLOOD VESSEL; DIABETIC ANGIOPATHY; FEMALE; GENE EXPRESSION REGULATION; GENETICS; HEART MUSCLE REVASCULARIZATION; MALE; MIDDLE AGED; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY;

AGED; APOPTOSIS; COLLAGEN; CORONARY VESSELS; DIABETIC ANGIOPATHIES; ELASTIN; FEMALE; GENE EXPRESSION REGULATION; GLUCOSE; HUMANS; INTERNAL MAMMARY-CORONARY ARTERY ANASTOMOSIS; MALE; MANNITOL; MIDDLE AGED; MUSCLE, SMOOTH, VASCULAR; PROTO-ONCOGENE PROTEINS C-BCL-2;

EID: 33745306974     PISSN: 00121797     EISSN: 00121797     Source Type: Journal    
DOI: 10.2337/db05-0949     Document Type: Article

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