Persistent Disruption of a Traumatic Memory by Postretrieval Inactivation of Glucocorticoid Receptors in the Amygdala

Biological Psychiatry

Volumn 62, Issue 1, 2007, Pages 33-39

  Tronel, Sophie ^a   Alberini, Cristina M ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

Amygdala; animal model; fear memory; glucocorticoid receptor; PTSD; reconsolidation

Indexed keywords

GLUCOCORTICOID RECEPTOR; GLUCOCORTICOID RECEPTOR ANTAGONIST; MIFEPRISTONE;

AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONDITIONING; CONTROLLED STUDY; FEAR; HISTOLOGY; MALE; MEMORY CONSOLIDATION; MEMORY DISORDER; NONHUMAN; POSTTRAUMATIC STRESS DISORDER; PRIORITY JOURNAL; RAT; TRAUMATIC MEMORY;

AMYGDALA; ANIMALS; CONDITIONING, CLASSICAL; DISEASE MODELS, ANIMAL; FEAR; HUMANS; MEMORY DISORDERS; MENTAL RECALL; RECEPTORS, GLUCOCORTICOID; STRESS DISORDERS, POST-TRAUMATIC;

EID: 34250199393     PISSN: 00063223     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biopsych.2006.09.009     Document Type: Article

References (65)

1. Alberini C.M. Mechanisms of memory stabilization: Are consolidation and reconsolidation similar or distinct processes?. Trend Neurosci 28 (2005) 51-56
2. Allen B.D., Sutanto W., and Jones M.T. A correlative study of RU38486 biopotency and competition with [3H]dexamethasone for receptors in the rat central nervous system. J Steroid Biochem 30 (1988) 411-415
3. Anokhin K.V., Tiunova A.A., and Rose S.P. Reminder effects-reconsolidation or retrieval deficit?. Pharmacological dissection with protein synthesis inhibitors following reminder for a passive-avoidance task in young chicks. Eur J Neurosci 15 (2002) 1759-1765
4. Asnis G.M., Kohn S.R., Henderson M., and Brown N.L. SSRIs versus non-SSRIs in post-traumatic stress disorder: An update with recommendations. Drugs 64 (2004) 383-404
5. Bouton M.E. Context and behavioral processes in extinction. Learn Mem 11 (2004) 485-494
6. Brogden R.N., Goa K.L., and Faulds D. Mifepristone. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential. Drugs 45 (1993) 384-409 Erratum in: Drugs 1993, 46:268
7. Bustos S.G., Maldonado H., and Molina V.A. Midazolam disrupts fear memory reconsolidation. Neuroscience 139 (2006) 831-842
8. Deacon B.J., and Abramowitz J.S. Cognitive and behavioral treatments for anxiety disorders: A review of meta-analytic findings. J Clin Psychol 60 (2004) 429-441
9. DeBattista C., and Belanoff J. The use of mifepristone in the treatment of neuropsychiatric disorders. Trends Endocrinol Metab 17 (2006) 117-121
10. Debiec J., and LeDoux J.E. Disruption of reconsolidation but not consolidation of auditory fear conditioning by noradrenergic blockade in the amygdala. Neuroscience 129 (2004) 267-272
11. Debiec J., LeDoux J.E., and Nader K. Cellular and systems reconsolidation in the hippocampus. Neuron 36 (2002) 527-538
12. Donley M.P., Schulkin J., and Rosen J.B. Glucocorticoid receptor antagonism in the basolateral amygdala and ventral hippocampus interferes with long-term memory of contextual fear. Behav Brain Res 164 (2005) 197-205
13. Duvarci S., and Nader K. Characterization of fear memory reconsolidation. J Neurosci 24 (2004) 9269-9275
14. Elzinga B.M., and Bremner J.D. Are the neural substrates of memory the final common pathway in posttraumatic stress disorder (PTSD)?. J Affect Disord 70 (2002) 1-17
15. Flores B.H., Kenna H., Keller J., Solvason H.B., and Schatzberg A.F. Clinical and biological effects of mifepristone treatment for psychotic depression. Neuropsychopharmacology 31 (2006) 628-636
16. Foa E.B. Psychosocial therapy for posttraumatic stress disorder. J Clin Psychiatry 67 suppl 2 (2006) 40-45
17. Frenkel L., Maldonado H., and Delorenzi A. Memory strengthening by a real-life episode during reconsolidation: An outcome of water deprivation via brain angiotensin II. Eur J Neurosci 22 (2005) 1757-1766
18. Grillon C., Southwick S.M., and Charney D.S. The psychobiological basis of posttraumatic stress disorder. Mol Psychiatry 1 (1996) 278-297
19. Heikinheimo O., and Kekkonen R. Dose-response relationships of RU 486. Ann Med 25 (1993) 71-76
20. Jellestad F.K., and Bakke H.K. Passive avoidance after ibotenic acid and radio frequency lesions in the rat amygdala. Physiol Behav 34 (1985) 299-305
21. Judge M.E., and Quartermain D. Characteristics of retrograde amnesia following reactivation of memory in mice. Physiol Behav 28 (1982) 585-590
22. Lattal K.M., and Abel T. Behavioral impairments caused by injections of the protein synthesis inhibitor anisomycin after contextual retrieval reverse with time. Proc Natl Acad Sci U S A 101 (2004) 4667-4672
23. Lewis D.J. A cognitive approach to experimental amnesia. Am J Psychol 89 (1976) 51-80
24. Liberzon I., Taylor S.F., Amdur R., Jung T.D., Chamberlain K.R., Minoshima S., et al. Brain activation in PTSD in response to trauma-related stimuli. Biol Psychiatry 45 (1999) 817-826
25. Mactutus C.F., Ferek J.M., and Riccio D.C. Amnesia induced by hyperthermia: An unusually profound, yet reversible, memory loss. Behav Neural Biol 3 (1980) 260-277
26. Mactutus C.F., and Riccio D.C. Hypotermia-induced retrograde amnesia. Role of body temperature in memory retrieval. Physiol Psychol 6 (1978) 18-22
27. McGaugh J.L. The amygdala modulates the consolidation of memories of emotionally arousing experiences. Annu Rev Neurosci 27 (2004) 1-28
28. McGaugh J.L., and Roozendaal B. Role of adrenal stress hormones in forming lasting memories in the brain. Curr Opin Neurobiol 12 (2002) 205-210
29. Milekic M.H., Brown S.D., Castellini C., and Alberini C.M. Persistent disruption of an established morphine conditioned place preference. J Neurosci 26 (2006) 3010-3020
30. Miller M.M., and McEwen B.S. Establishing an agenda for translational research on PTSD. Ann N Y Acad Sci 1071 (2006) 294-312
31. Miller R.R., and Kraus J.N. Somatic and autonomic indexes of recovery from electroconvulsive shock-induced amnesia in rats. Physiol Psychol 91 (1977) 434-442
32. Millin P.M., Moody E.W., and Riccio D.C. Interpretations of retrograde amnesia: Old problems redux. Nat Rev Neurosci 2 (2001) 68-70
33. Nader K. Memory traces unbound. Trends Neurosci 26 (2003) 65-72
34. Nader K., Schafe G.E., and Le Doux J.E. Fear memories require protein synthesis in the amygdala for reconsolidation after retrieval. Nature 406 (2000) 722-726
35. Oitzl M.S., Fluttert M., Sutanto W., and de Kloet E.R. Continuous blockade of brain glucocorticoid receptors facilitates spatial learning and memory in rats. Eur J Neurosci 10 (1998) 3759-3766
36. Orr S.P., Metzger L.J., and Pitman R.K. Psychophysiology of post-traumatic stress disorder. Psychiatr Clin North Am 25 (2002) 271-293
37. Paxinos G., and Watson C. The Rat Brain in Stereotactic Coordinates (1998), Academic, New York
38. Pedreira M.E., and Maldonado H. Protein synthesis subserves reconsolidation or extinction depending on reminder duration. Neuron 38 (2003) 863-869
39. Prado-Alcala R.A., Diaz Del Guante M.A., Garin-Aguilar M.E., Diaz-Trujillo A., Quirarte G.L., and McGaugh J.L. Amygdala or hippocampus inactivation after retrieval induces temporary memory deficit. Neurobiol Learn Mem 86 2 (2006) 144-149
40. Protopopescu X., Pan H., Tuescher O., Cloitre M., Goldstein M., Engelien W., et al. Differential time courses and specificity of amygdala activity in posttraumatic stress disorder subjects and normal control subjects. Biol Psychiatry 57 (2005) 464-473
41. Przybyslawski J., Roullet P., and Sara S.J. Attenuation of emotional and nonemotional memories after their reactivation: Role of beta adrenergic receptors. J Neurosci 19 (1999) 6623-6628
42. Quirk G.J., Garcia R., and Gonzalez-Lima F. Prefrontal mechanisms in extinction of conditioned fear. Biol Psychiatry 60 4 (2006) 337-343
43. Rasmusson A.M., and Charney D.S. Animal models of relevance to PTSD. Ann N Y Acad Sci 821 (1997) 332-351
44. Rau V., DeCola J.P., and Fanselow M.S. Stress-induced enhancement of fear learning: An animal model of posttraumatic stress disorder. Neurosci Biobehav Rev 29 (2005) 1207-1223
45. Ressler K.J., Rothbaum B.O., Tannenbaum L., Anderson P., Graap K., Zimand E., et al. Cognitive enhancers as adjuncts to psychotherapy: Use of D-cycloserine in phobic individuals to facilitate extinction of fear. Arch Gen Psychiatry 61 (2004) 1136-1144
46. Roozendaal B. 1999 Curt P. Richter award. Glucocorticoids and the regulation of memory consolidation. Psychoneuroendocrinology 25 (2000) 213-238
47. Roozendaal B. Stress and memory: Opposing effects of glucocorticoids on memory consolidation and memory retrieval. Neurobiol Learn Mem 78 (2002) 578-595
48. Roozendaal B., and McGaugh J.L. Glucocorticoid receptor agonist and antagonist administration into the basolateral but not central amygdala modulates memory storage. Neurobiol Learn Mem 67 (1997) 176-179
49. Roozendaal B., Williams C.L., and McGaugh J.L. Glucocorticoid receptor activation in the rat nucleus of the solitary tract facilitates memory consolidation: Involvement of the basolateral amygdala. Eur J Neurosci 11 (1999) 1317-1323
50. Rothbaum B.O., Astin M.C., and Marsteller F. Prolonged exposure versus eye movement desensitization and reprocessing (EMDR) for PTSD rape victims. J Trauma Stress 18 (2005) 607-616
51. Salinska E., Bourne R.C., and Rose S.P. Reminder effects: The molecular cascade following a reminder in young chicks does not recapitulate that following training on a passive avoidance task. Eur J Neurosci 19 (2004) 3042-3047
52. Sandi C. The role and mechanisms of action of glucocorticoid involvement in memory storage. Neural Plast 6 (1998) 41-52
53. Sandi C., and Rose S.P. Corticosteroid receptor antagonists are amnestic for passive avoidance learning in day-old chicks. Eur J Neurosci 6 (1994) 1292-1297
54. Sara S.J. Retrieval and reconsolidation: Toward a neurobiology of remembering. Learn Mem 7 (2000) 73-84
55. Shalev A.Y., Ragel-Fuchs Y., and Pitman R.K. Conditioned fear and psychological trauma. Biol Psychiatry 31 (1992) 863-865
56. Sherry J.M., Hale M.W., and Crowe S.F. The effects of the dopamine D1 receptor antagonist SCH23390 on memory reconsolidation following reminder-activated retrieval in day-old chicks. Neurobiol Learn Mem 83 (2005) 104-112
57. Shin L.M., Kosslyn S.M., McNally R.J., Alpert N.M., Thompson W.L., Rauch S.L., et al. Visual imagery and perception in posttraumatic stress disorder. A positron emission tomographic investigation. Arch Gen Psychiatry 54 (1997) 233-241
58. Shin L.M., Wright C.I., Cannistraro P.A., Wedig M.M., McMullin K., Martis B., et al. A functional magnetic resonance imaging study of amygdala and medial prefrontal cortex responses to overtly presented fearful faces in posttraumatic stress disorder. Arch Gen Psychiatry 62 (2005) 273-281
59. Siegmund A., and Wotjak C.T. Toward an animal model of posttraumatic stress disorder. Ann N Y Acad Sci 1071 (2006) 324-334
60. Teutsch G., Costerousse G., Deraedt R., Benzoni J., Fortin M., and Philibert D. 17 alpha-alkynyl-11 beta, 17-dihydroxyandrostane derivatives: A new class of potent glucocorticoids. Steroids 38 (1981) 651-665
61. Tronel S., Milekic M.H., and Alberini C.M. Linking new information to a reactivated memory requires consolidation and not reconsolidation mechanisms. PLoS Biol 3 (2005) e293
62. Tronson N.C., Wiseman S.L., Olausson P., and Taylor J.R. Bidirectional behavioral plasticity of memory reconsolidation depends on amygdalar protein kinase A. Nat Neurosci 9 (2006) 167-169
63. Vianna M.R., Izquierdo L.A., Barros D.M., de Souza M.M., Rodrigues C., Sant'Anna M.K., et al. Pharmacological differences between memory consolidation of habituation to an open field and inhibitory avoidance learning. Braz J Med Biol Res 34 (2001) 233-240
64. Yang Y.L., Chao P.K., and Lu K.T. Systemic and intra-amygdala administration of glucocorticoid agonist and antagonist modulate extinction of conditioned fear. Neuropsychopharmacology 31 (2006) 912-924
65. Yehuda R. Biology of posttraumatic stress disorder. J Clin Psychiatry 62 suppl 17 (2001) 41-46