Cytotoxicity and mode of action of four naturally occuring flavonoids from the genus dorstenia: Gancaonin Q, 4-hydroxylonchocarpin, 6-prenylapigenin, and 6,8-diprenyleriodictyol

Planta Medica

Volumn 77, Issue 18, 2011, Pages 1984-1989

  Kuete, Victor ^a,c   Ngameni, Bathelemy ^b   Wiench, Benjamin ^c   Krusche, Benjamin ^c   Horwedel, Cindy ^c   Ngadjui, Bonaventure T ^b   Efferth, Thomas ^c  

^a UNIVERSITY OF DSCHANG   (Cameroon)

^b UNIVERSITY OF YAOUNDÉ I   (Cameroon)

^c JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

angiogenesis; apoptosis; caspase; cytotoxicity; Dorstenia; flavonoids; Moraceae

Indexed keywords

4 HYDROXYLONCHOCARPIN; 6 PRENYLAPIGENIN; 6,8 DIPRENYLERIODICTYOL; FLAVONOID; GANCAONIN Q; UNCLASSIFIED DRUG;

ANTIANGIOGENIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CAPILLARY; CHORIOALLANTOIS; CONTROLLED STUDY; DORSTENIA; DRUG CYTOTOXICITY; DRUG MECHANISM; DRUG STRUCTURE; HUMAN; HUMAN CELL; IC 50; LIVER CELL; MEDICINAL PLANT;

ANGIOGENESIS INHIBITORS; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CASPASE 3; CASPASE 7; CELL CYCLE; CELL SURVIVAL; CHICK EMBRYO; CHORIOALLANTOIC MEMBRANE; DOXORUBICIN; ENZYME ACTIVATION; FLAVONES; FLAVONOIDS; HELA CELLS; HEPATOCYTES; HUMANS; INHIBITORY CONCENTRATION 50; MORACEAE; NEOVASCULARIZATION, PATHOLOGIC; OXAZINES; PLANT EXTRACTS; QUAIL; STRUCTURE-ACTIVITY RELATIONSHIP; TIME FACTORS; XANTHENES; ZYGOTE;

DORSTENIA; MORACEAE; PHASIANIDAE;

EID: 84155164754     PISSN: 00320943     EISSN: 14390221     Source Type: Journal    
DOI: 10.1055/s-0031-1280023     Document Type: Article

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