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Volumn 37, Issue 6, 2011, Pages 439-446

Schisandrin B enhances the glutathione redox cycling and protects against oxidant injury in different types of cultured cells

Author keywords

Antioxidant; Glutathione; Glutathione recovery capacity; Oxidative stress; Schisandrins

Indexed keywords

GLUTATHIONE; N,N' BIS(CHLOROETHYL) N NITROSOUREA; NITROSOUREA DERIVATIVE; SCHIZANDRIN A; SCHIZANDRIN B; SCHIZANDRIN C; UNCLASSIFIED DRUG;

EID: 84155162549     PISSN: 09516433     EISSN: 18728081     Source Type: Journal    
DOI: 10.1002/biof.179     Document Type: Article
Times cited : (14)

References (25)
  • 1
    • 0024789945 scopus 로고
    • Oxidative stress. Biochemistry and human disease
    • Bast, A. and Goris, R. J. ( 1989) Oxidative stress. Biochemistry and human disease. Pharm. Weekbl Sci. 11, 199-206.
    • (1989) Pharm. Weekbl Sci. , vol.11 , pp. 199-206
    • Bast, A.1    Goris, R.J.2
  • 2
    • 0025298097 scopus 로고
    • Glutathione-dependent protection against oxidative injury
    • Shan, X. Q., Aw, T. Y., and Jones, D. P. ( 1990) Glutathione-dependent protection against oxidative injury. Pharmacol. Ther. 47, 61-71.
    • (1990) Pharmacol. Ther. , vol.47 , pp. 61-71
    • Shan, X.Q.1    Aw, T.Y.2    Jones, D.P.3
  • 3
    • 0036719065 scopus 로고    scopus 로고
    • Early redox imbalance mediates hydroperoxide-induced apoptosis in mitotic competent undifferentiated PC-12 cells
    • Pias, E. K. and Aw, T. Y. ( 2002) Early redox imbalance mediates hydroperoxide-induced apoptosis in mitotic competent undifferentiated PC-12 cells. Cell Death Differ. 9, 1007-1016.
    • (2002) Cell Death Differ. , vol.9 , pp. 1007-1016
    • Pias, E.K.1    Aw, T.Y.2
  • 5
    • 65049089113 scopus 로고    scopus 로고
    • Regulation of glutathione synthesis
    • Lu, S. C. ( 2009) Regulation of glutathione synthesis. Mol. Aspects Med. 30, 42-59.
    • (2009) Mol. Aspects Med. , vol.30 , pp. 42-59
    • Lu, S.C.1
  • 6
    • 0032702088 scopus 로고    scopus 로고
    • Schisandra chinensis (Turcz) Baill
    • Hancke, J. L., Burgos, R. A., and Ahumada, F. ( 1999) Schisandra chinensis (Turcz) Baill. Fitotherapia 70, 451-471.
    • (1999) Fitotherapia , vol.70 , pp. 451-471
    • Hancke, J.L.1    Burgos, R.A.2    Ahumada, F.3
  • 7
    • 41849109537 scopus 로고    scopus 로고
    • Schisandrin B enhances renal mitochondrial antioxidant status, functional and structural integrity, and protects against gentamicin-induced nephrotoxicity in rats
    • Chiu, P. Y., Leung, H. Y., and Ko, K. M. ( 2008) Schisandrin B enhances renal mitochondrial antioxidant status, functional and structural integrity, and protects against gentamicin-induced nephrotoxicity in rats. Biol. Pharm. Bull. 31, 602-605.
    • (2008) Biol. Pharm. Bull. , vol.31 , pp. 602-605
    • Chiu, P.Y.1    Leung, H.Y.2    Ko, K.M.3
  • 8
    • 0036715310 scopus 로고    scopus 로고
    • Schisandrin B protects against tert-butylhydroperoxide induced cerebral toxicity by enhancing glutathione antioxidant status in mouse brain
    • Ko, K. M. and Lam, B. Y. ( 2002) Schisandrin B protects against tert-butylhydroperoxide induced cerebral toxicity by enhancing glutathione antioxidant status in mouse brain. Mol. Cell Biochem. 238, 181-186.
    • (2002) Mol. Cell Biochem. , vol.238 , pp. 181-186
    • Ko, K.M.1    Lam, B.Y.2
  • 9
    • 33747319849 scopus 로고    scopus 로고
    • Chronic schisandrin B treatment improves mitochondrial antioxidant status and tissue heat shock protein production in various tissues of young adult and middle-aged rats
    • Chiu, P. Y., Leung, H. Y., Poon, M. K., and Ko, K. M. ( 2006) Chronic schisandrin B treatment improves mitochondrial antioxidant status and tissue heat shock protein production in various tissues of young adult and middle-aged rats. Biogerontology 7, 199-210.
    • (2006) Biogerontology , vol.7 , pp. 199-210
    • Chiu, P.Y.1    Leung, H.Y.2    Poon, M.K.3    Ko, K.M.4
  • 10
    • 46449093978 scopus 로고    scopus 로고
    • Schisandrin B enhances cerebral mitochondrial antioxidant status and structural integrity, and protects against cerebral ischemia/reperfusion injury in rats
    • Chen, N., Chiu, P. Y., and Ko, K. M. ( 2008) Schisandrin B enhances cerebral mitochondrial antioxidant status and structural integrity, and protects against cerebral ischemia/reperfusion injury in rats. Biol. Pharm. Bull. 31, 1387-1391.
    • (2008) Biol. Pharm. Bull. , vol.31 , pp. 1387-1391
    • Chen, N.1    Chiu, P.Y.2    Ko, K.M.3
  • 11
    • 0032769002 scopus 로고    scopus 로고
    • Schisandrin B protects against myocardial ischemia-reperfusion injury by enhancing myocardial glutathione antioxidant status
    • Yim, T. K. and Ko, K. M. ( 1999) Schisandrin B protects against myocardial ischemia-reperfusion injury by enhancing myocardial glutathione antioxidant status. Mol. Cell Biochem. 196, 151-156.
    • (1999) Mol. Cell Biochem. , vol.196 , pp. 151-156
    • Yim, T.K.1    Ko, K.M.2
  • 12
    • 0032897109 scopus 로고    scopus 로고
    • Methylenedioxy group and cyclooctadiene ring as structural determinants of schisandrin in protecting against myocardial ischemia-reperfusion injury in rats
    • Yim, T. K. and Ko, K. M. ( 1999) Methylenedioxy group and cyclooctadiene ring as structural determinants of schisandrin in protecting against myocardial ischemia-reperfusion injury in rats. Biochem. Pharmacol. 57, 77-81.
    • (1999) Biochem. Pharmacol. , vol.57 , pp. 77-81
    • Yim, T.K.1    Ko, K.M.2
  • 14
    • 77952365301 scopus 로고    scopus 로고
    • Schisandrin B-induced glutathione antioxidant response and cardioprotection are mediated by reactive oxidant species production in rat hearts
    • Chen, N. and Ko, M. ( 2010) Schisandrin B-induced glutathione antioxidant response and cardioprotection are mediated by reactive oxidant species production in rat hearts. Biol. Pharm. Bull. 33, 825-829.
    • (2010) Biol. Pharm. Bull. , vol.33 , pp. 825-829
    • Chen, N.1    Ko, M.2
  • 15
    • 76449098446 scopus 로고    scopus 로고
    • Long-term schisandrin B treatment mitigates age-related impairments in mitochondrial antioxidant status and functional ability in various tissues, and improves the survival of aging C57BL/6J mice
    • Ko, K. M., Chen, N., Leung, H. Y., Leong, E. P., Poon, M. K., and Chiu, P. Y. ( 2008) Long-term schisandrin B treatment mitigates age-related impairments in mitochondrial antioxidant status and functional ability in various tissues, and improves the survival of aging C57BL/6J mice. Biofactors 34, 331-342.
    • (2008) Biofactors , vol.34 , pp. 331-342
    • Ko, K.M.1    Chen, N.2    Leung, H.Y.3    Leong, E.P.4    Poon, M.K.5    Chiu, P.Y.6
  • 16
    • 78549250675 scopus 로고    scopus 로고
    • Schisandrin B co-treatment ameliorates the impairment on mitochondrial antioxidant status in various tissues of long-term ethanol treated rats
    • Lam, P. Y., Chiu, P. Y., Leung, H. Y., Chen, N., Leong, P. K., and Ko, K. M. ( 2010) Schisandrin B co-treatment ameliorates the impairment on mitochondrial antioxidant status in various tissues of long-term ethanol treated rats. Fitoterapia 81, 1239-1245.
    • (2010) Fitoterapia , vol.81 , pp. 1239-1245
    • Lam, P.Y.1    Chiu, P.Y.2    Leung, H.Y.3    Chen, N.4    Leong, P.K.5    Ko, K.M.6
  • 17
    • 33748331142 scopus 로고    scopus 로고
    • (-)Schisandrin B is more potent than its enantiomer in enhancing cellular glutathione and heat shock protein production as well as protecting against oxidant injury in H9c2 cardiomyocytes
    • Chiu, P. Y., Leung, H. Y., Poon, M. K., Mak, D. H., and Ko, K. M. ( 2006) (-)Schisandrin B is more potent than its enantiomer in enhancing cellular glutathione and heat shock protein production as well as protecting against oxidant injury in H9c2 cardiomyocytes. Mol. Cell Biochem. 289, 185-191.
    • (2006) Mol. Cell Biochem. , vol.289 , pp. 185-191
    • Chiu, P.Y.1    Leung, H.Y.2    Poon, M.K.3    Mak, D.H.4    Ko, K.M.5
  • 18
    • 33744815331 scopus 로고    scopus 로고
    • Effects of schisandrin B enantiomers on cellular glutathione and menadione toxicity in AML12 hepatocytes
    • Chiu, P. Y., Leung, H. Y., Poon, M. K., Mak, D. H., and Ko, K. M. ( 2006) Effects of schisandrin B enantiomers on cellular glutathione and menadione toxicity in AML12 hepatocytes. Pharmacology 77, 63-70.
    • (2006) Pharmacology , vol.77 , pp. 63-70
    • Chiu, P.Y.1    Leung, H.Y.2    Poon, M.K.3    Mak, D.H.4    Ko, K.M.5
  • 19
    • 79951662032 scopus 로고    scopus 로고
    • (-)Schisandrin B ameliorates paraquat-induced oxidative stress by suppressing glutathione depletion and enhancing glutathione recovery in differentiated PC12 cells
    • Lam, P. Y. and Ko, K. M. ( 2011) (-)Schisandrin B ameliorates paraquat-induced oxidative stress by suppressing glutathione depletion and enhancing glutathione recovery in differentiated PC12 cells. Biofactors 37, 51-57.
    • (2011) Biofactors , vol.37 , pp. 51-57
    • Lam, P.Y.1    Ko, K.M.2
  • 20
    • 0028970756 scopus 로고
    • Effect of schisandrin B on hepatic glutathione antioxidant system in mice: protection against carbon tetrachloride toxicity
    • Ip, S. P., Poon, M. K., Wu, S. S., Che, C. T., Ng, K. H., Kong, Y. C., and Ko, K. M. ( 1995) Effect of schisandrin B on hepatic glutathione antioxidant system in mice: protection against carbon tetrachloride toxicity. Planta. Med. 61, 398-401.
    • (1995) Planta. Med. , vol.61 , pp. 398-401
    • Ip, S.P.1    Poon, M.K.2    Wu, S.S.3    Che, C.T.4    Ng, K.H.5    Kong, Y.C.6    Ko, K.M.7
  • 21
    • 9444228870 scopus 로고    scopus 로고
    • Schisandrin B protects myocardial ischemia-reperfusion injury partly by inducing Hsp25 and Hsp70 expression in rats
    • Chiu, P. Y. and Ko, K. M. ( 2004) Schisandrin B protects myocardial ischemia-reperfusion injury partly by inducing Hsp25 and Hsp70 expression in rats. Mol. Cell Biochem. 266, 139-144.
    • (2004) Mol. Cell Biochem. , vol.266 , pp. 139-144
    • Chiu, P.Y.1    Ko, K.M.2
  • 22
    • 43049084732 scopus 로고    scopus 로고
    • Schisandrin B stereoisomers protect against hypoxia/reoxygenation-induced apoptosis and inhibit associated changes in Ca2+-induced mitochondrial permeability transition and mitochondrial membrane potential in H9c2 cardiomyocytes
    • Chiu, P. Y., Luk, K. F., Leung, H. Y., Ng, K. M., and Ko, K. M. ( 2008) Schisandrin B stereoisomers protect against hypoxia/reoxygenation-induced apoptosis and inhibit associated changes in Ca2+-induced mitochondrial permeability transition and mitochondrial membrane potential in H9c2 cardiomyocytes. Life Sci. 82, 1092-1101.
    • (2008) Life Sci. , vol.82 , pp. 1092-1101
    • Chiu, P.Y.1    Luk, K.F.2    Leung, H.Y.3    Ng, K.M.4    Ko, K.M.5
  • 23
    • 36749096845 scopus 로고    scopus 로고
    • Schisandrin B prevents doxorubicin-induced cardiotoxicity via enhancing glutathione redox cycling
    • Li, L., Pan, Q., Han, W., Liu, Z., Li, L., and Hu, X. ( 2007) Schisandrin B prevents doxorubicin-induced cardiotoxicity via enhancing glutathione redox cycling. Clin. Cancer Res. 13, 6753-6760.
    • (2007) Clin. Cancer Res. , vol.13 , pp. 6753-6760
    • Li, L.1    Pan, Q.2    Han, W.3    Liu, Z.4    Li, L.5    Hu, X.6
  • 24
    • 0033231162 scopus 로고    scopus 로고
    • Biologic and pharmacologic regulation of mammalian glutathione synthesis
    • Griffith, O. W. ( 1999) Biologic and pharmacologic regulation of mammalian glutathione synthesis. Free Radic. Biol Med. 27, 922-935.
    • (1999) Free Radic. Biol Med. , vol.27 , pp. 922-935
    • Griffith, O.W.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.