Neurotrophin-4 modulates the mechanotransducer Ca v3.2 T-type calcium current in mice down-hair neurons

Biochemical Journal

Volumn 441, Issue 1, 2012, Pages 463-471

  Hilaire, Cécile ^a,b   Lucas, Olivier ^a,b   Valmier, Jean ^a,b   Scamps, Frédérique ^a,b  

^a Montpellier University Medical Center   (France)

^b HÔPITAL SAINT ELOI   (France)

Author keywords

Dorsal root ganglion; Down hair neuron; Neurotrophin 4; Sensory neuron; T type Ca 2+ current

Indexed keywords

CALCIUM CHANNEL T TYPE; FLUOROGOLD; NEUROTROPHIN 4; PHOSPHATIDYLINOSITOL 3 KINASE; TROPOMYOSIN; TROPOMYOSIN RECEPTOR KINASE B; UNCLASSIFIED DRUG;

ABLATION THERAPY; AMPLITUDE MODULATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CALCIUM CURRENT; CONTROLLED STUDY; DOWN HAIR NEURON; ENZYME ACTIVATION; FEMALE; GENE DELETION; GENE LOSS; GENETIC TRANSCRIPTION; HAIR FOLLICLE; IMMUNOPOTENTIATION; INNERVATION; MECHANOTRANSDUCTION; MOUSE; NERVE CELL; NERVE FIBER TRANSECTION; NOCICEPTION; NONHUMAN; PERIPHERAL NERVE; POSTTRANSCRIPTIONAL GENE SILENCING; PRIORITY JOURNAL; PROTEIN EXPRESSION; SENSORY NERVE CELL; SPINAL GANGLION;

ANIMALS; CALCIUM; CALCIUM CHANNELS, T-TYPE; CALCIUM SIGNALING; FEMALE; GENE EXPRESSION REGULATION; HAIR; MEMBRANE POTENTIALS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NERVE GROWTH FACTORS; NEURONS;

EID: 84055219376     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20111147     Document Type: Article

References (29)

1. Martin, J. H. and Jessell, T. M. (1992) Modality coding in the somatic sensory system. In Sensory Neurons, Diversity, Development, and Plasticity (Scott, S. K., ed.), pp. 341-352, Oxford University Press, New York
2. Tsunozaki, M. and Bautista, D. M. (2009) Mammalian somatosensory mechanotransduction. Curr. Opin. Neurobiol. 19, 362-369
3. Stucky, C. L., Shin, J. B. and Lewin, G. R. (2002) Neurotrophin-4: a survival factor for adult sensory neurons. Curr. Biol. 12, 1401-1404 (Pubitemid 34915542)
4. Shin, J.-B., Martinez-Salgado, C., Heppenstall, P. A. and Lewin, G. R. (2003) A T-type calcium channel required for normal function of a mammalian mechanoreceptor. Nat. Neurosci. 6, 1-7
5. Dubreuil, A. S., Boukhaddaoui, H., Desmadryl, G., Martinez-Salgado, C., Moshourab, R., Lewin, G. R., Carroll, P., Valmier, J. and Scamps, F. (2004) Role of T-type calcium current in identified D-hair mechanoreceptor neurons studied in vitro. J. Neurosci. 24, 8480-8484 (Pubitemid 39313770)
6. 2+ current is a molecular determinant of excitatory effects of GABA in adult sensory neurons. Mol. Cell. Neurosci. 36, 293-303
7. Mcallister, A. K., Katz, L. C. and Lo, D. C. (1999) Neurotrophins and synaptic plasticity. Annu. Rev. Neurosci. 22, 295-318 (Pubitemid 29144890)
8. Carroll, P., Lewin, G. R., Koltzenburg, M., Toyka, K. V. and Thoenen, H. (1998) A role for BDNF in mechanosensation. Nat. Neurosci. 1, 42-46 (Pubitemid 128652640)
9. McIlwrath, S. L., Hu, J., Anirudhan, G., Shin, J. B. and Lewin, G. R. (2005) The sensory mechanotransduction ion channel ASIC2 (acid sensitive ion channel 2) is regulated by neurotrophin availability. Neuroscience 131, 499-511 (Pubitemid 40222457)
10. Lechner, S. G., Frenzel, H., Wang, R. and Lewin, G. R. (2009) Developmental waves of mechanosensitivity acquisition in sensory neuron subtypes during embryonic development. EMBO J. 28, 1479-1491
11. 2+ channels in mechanosensation. Cell Calcium 40, 165-174
12. 2+ channels. Science 302, 1416-1418
13. Conover, J. C., Erickson, J. T., Katz, D. M., Bianchi, L. M., Poueymirou, W. T., McClain, J., Pan, L., Helgren, M., Ip, N. Y., Boland, P. et al. (1995) Neuronal deficits, not involving motor neurons, in mice lacking BDNF and/or NT4. Nature 375, 235-238
14. Andre, S., Boukhaddaoui, H., Campo, B., Al-Jumaily, M., Mayeux, V., Greuet, D., Valmier, J. and Scamps, F. (2003) Axotomy-induced expression of calcium-activated chloride current in subpopulations of mouse dorsal root ganglion neurons. J. Neurophysiol. 90, 3764-3773 (Pubitemid 37541909)
15. Pieraut, S., Laurent-Matha, V., Sar, C., Hubert, T., Mechaly, I., Hilaire, C., Mersel, M., Delpire, E., Valmier, J. and Scamps, F. (2007) NKCC1 phosphorylation stimulates neurite growth of injured adult sensory neurons. J. Neurosci. 27, 6751-6759 (Pubitemid 46983429)
16. Jagodic, M. M., Pathirathna, S., Nelson, M. T., Mancuso, S., Joksovic, P. M., Rosenberg, E. R., Bayliss, D. A., Jevtovic-Todorovic, V. and Todorovic, S. M. (2007) Cell-specific alterations of T-type calcium current in painful diabetic neuropathy enhance excitability of sensory neurons. J. Neurosci. 27, 3305-3316 (Pubitemid 46474118)
17. Stucky, C. L., DeChiara, T., Lindsay, R. M., Yancopoulos, G. D. and Koltzenburg, M. (1998) Neurotrophin 4 is required for the survival of a subclass of hair follicle receptors. J. Neurosci. 18, 7040-7046 (Pubitemid 28388033)
18. Obata, K., Katsura, H., Sakurai, J., Kobayashi, K., Yamanaka, H., Dai, Y., Fukuoka, T. and Noguchi, K. (2006) Suppression of the p75 neurotrophin receptor in uninjured sensory neurons reduces neuropathic pain after nerve injury. J. Neurosci. 26, 11974-11986 (Pubitemid 44772108)
19. Bonilla, I. E., Tanabe, K. and Strittmatter, S. M. (2002) Small proline-rich repeat protein 1A is expressed by axotomized neurons and promotes axonal outgrowth. J. Neurosci. 22, 1303-1315 (Pubitemid 34163732)
20. 2+ channels in the rat and mouse thalamus. J. Physiol. 574, 415-430
21. Chemin, J., Monteil, A., Dubel, S., Nargeot, J. and Lory, P. (2001) The α1I T-type calcium channel exhibits faster gating properties when overexpressed in neuroblastoma/glioma NG 108-15 cells. Eur. J. Neurosci. 14, 1678-1686 (Pubitemid 35478036)
22. Chemin, J., Nargeot, J. and Lory, P. (2002) Neuronal T-type α1H calcium channels induce neuritogenesis and expression of high-voltage-activated calcium channels in the NG108-15 cell line. J. Neurosci. 22, 6856-6862 (Pubitemid 35379143)
23. Wang, R. and Lewin, G. R. (2011) The Cav3.2 T-type calcium channel regulates temporal coding in mouse mechanoreceptors. J. Physiol. 589, 2229-2243
24. Botchkarev, V. A., Botchkareva, N. V., Peters, E. M. and Paus, R. (2004) Epithelial growth control by neurotrophins: leads and lessons from the hair follicle. Prog. Brain Res 146, 493-513 (Pubitemid 37541401)
25. Krimm, R. F., Davis, B. M., Noel, T. and Albers, K. M. (2006) Overexpression of neurotrophin 4 in skin enhances myelinated sensory endings but does not influence sensory neuron number. J. Comp. Neurol. 498, 455-465 (Pubitemid 44232687)
26. Stucky, C. L. and Koltzenburg, M. (1997) The low-affinity neurotrophin receptor p75 regulates the function but not the selective survival of specific subpopulations of sensory neurons. J. Neurosci. 17, 4398-4405 (Pubitemid 27220630)
27. Huang, E. J. and Reichardt, L. F. (2003) Trk receptors: roles in neuronal signal transduction. Annu. Rev. Biochem. 72, 609-642 (Pubitemid 36930455)
28. 2+channel expression in chick nodose ganglion neurons. Dev. Neurobiol. 67, 1915-1931
29. 2+channels: a paradigm for childhood absence epilepsy mutations. J. Neurosci. 27, 322-330