Neurotrophin-4: A survival factor for adult sensory neurons

Current Biology

Volumn 12, Issue 16, 2002, Pages 1401-1404

  Stucky, Cheryl L ^a,b   Shin, Jung Bum ^a  

^a MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^b MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; NERVE GROWTH FACTOR; NEUROPROTECTIVE AGENT; NEUROTROPHIN 3; NEUROTROPHIN 4;

AGING; ANIMAL; APOPTOSIS; ARTICLE; CYTOLOGY; ELECTROPHYSIOLOGY; GENETICS; IN SITU HYBRIDIZATION; MECHANORECEPTOR; METABOLISM; MOUSE; MOUSE MUTANT; PHYSIOLOGY; SENSORY NERVE CELL;

AGING; ANIMALS; APOPTOSIS; ELECTROPHYSIOLOGY; IN SITU HYBRIDIZATION; MECHANORECEPTORS; MICE; MICE, KNOCKOUT; NERVE GROWTH FACTORS; NEURONS, AFFERENT; NEUROPROTECTIVE AGENTS; NEUROTROPHIN 3; RECEPTOR, TRKB; ANIMAL; SUPPORT, U.S. GOV'T, P.H.S.;

ANIMALIA;

EID: 0037143446     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(02)01072-2     Document Type: Article

References (25)

1. Neurotrophins: Roles in neuronal development and function
2. NT-3, BDNF, and NGF in the developing rat nervous system: Parallel as well as reciprocal patterns of expression
3. Regulation of NGF-family ligands and receptors in adulthood and senescence: Correlation to degenerative and regenerative changes in cutaneous innervation
4. Nerve growth factors (NGF, BDNF) enhance axonal regeneration but are not required for survival of adult sensory neurons
5. Specific subtypes of cutaneous mechanoreceptors require neurotrophin-3 following peripheral target innervation
6. Neurotrophin 4 is required for the survival of a subclass of hair follicle receptors
7. Point mutation in trkB causes loss of NT4-dependent neurons without major effects on diverse BDNF responses
8. Neurotrophins and the specification of neuronal phenotype
9. Sense and specificity: A molecular identity for nociceptors
10. Receptive properties of mouse sensory neurons innervating hairy skin
11. Loss of brain-derived neurotrophic factor-dependent neural crest-derived sensory neurons in neurotrophin-4 mutant mice
12. Attenuation of a caspase-3 dependent cell death in NT4- and p75-deficient embryonic sensory neurons
13. Requirement for nerve growth factor in the development of myelinated nociceptors in vivo
14. On the role of nerve growth factor in the development of myelinated nociceptors
15. Morphological and biochemical cell types of sensory neurons
16. Neurotrophin receptor genes are expressed in distinct patterns in developing dorsal root ganglia
17. A role for BDNF in mechanosensation
18. Overexpression of brain-derived neurotrophic factor enhances sensory innervation and selectively increases neuron number
19. Anatomical evidence supporting the potential for modulation by multiple neurotrophins in the majority of adult lumbar sensory neurons
20. Neurotrophin-4: The odd one out in the neurotrophin family
21. Neurotrophin switching: Where does it stand?
22. BDNF but not NT-4 is required for normal flexion reflex plasticity and function
23. Lack of neurotrophin-3 leads to deficiencies in the peripheral nervous system and loss of limb proprioceptive afferents
24. Sensory but not motor neuron deficits in mice lacking NT4 and BDNF
25. Stomatin, a MEC-2 like protein, is expressed by mammalian sensory neurons