Liver-specific Commd1 knockout mice are susceptible to hepatic copper accumulation

PLoS ONE

Volumn 6, Issue 12, 2011, Pages

  Vonk, Willianne I M ^a   Bartuzi, Paulina ^b   de Bie, Prim ^a,d   Kloosterhuis, Niels ^b   Wichers, Catharina G K ^a   Berger, Ruud ^a   Haywood, Susan ^c   Klomp, Leo W J ^a   Wijmenga, Cisca ^a,b   van de Sluis, Bart ^b  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^c UNIVERSITY OF LIVERPOOL   (United Kingdom)

^d TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

CERULOPLASMIN; COPPER; METALLOTHIONEIN I; METALLOTHIONEIN II; WILSON DISEASE PROTEIN; COMMD1 PROTEIN, MOUSE; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

AGE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL FOOD; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHEMICAL ANALYSIS; COMMD1 GENE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; COPPER METABOLISM; DIETARY INTAKE; EMBRYO; FEMALE; GENE; GENE EXPRESSION; GENETIC SUSCEPTIBILITY; HISTOPATHOLOGY; KNOCKOUT MOUSE; LIVER FUNCTION; LIVER INJURY; LIVER TOXICITY; MALE; MOUSE; NONHUMAN; PHENOTYPE; PROTEIN STABILITY; PROTEIN SYNTHESIS; WILD TYPE; ANIMAL; GENETIC PREDISPOSITION; GENETICS; LIVER; METABOLISM; MOUSE MUTANT;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; COPPER; GENETIC PREDISPOSITION TO DISEASE; LIVER; MICE; MICE, KNOCKOUT;

EID: 84055207512     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0029183     Document Type: Article

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