COMMD1 downregulates the epithelial sodium channel through Nedd4-2

American Journal of Physiology - Renal Physiology

Volumn 298, Issue 6, 2010, Pages

  Ke, Ying ^a   Butt, A Grant ^a   Swart, Marianne ^a   Liu, Yong Feng ^a   McDonald, Fiona J ^a  

^a UNIVERSITY OF OTAGO   (New Zealand)

Author keywords

Akt1; Insulin; Kidney; SGK1

Indexed keywords

AMILORIDE; COPPER METABOLISM MURR1 DOMAIN CONTAINING PROTEIN 1; EPITHELIAL SODIUM CHANNEL; INSULIN; PROTEIN DERIVATIVE; PROTEIN KINASE B; SERUM AND GLUCOCORTICOID REGULATED KINASE 1; UBIQUITIN; UBIQUITIN PROTEIN LIGASE NEDD4; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL SURFACE; CONTROLLED STUDY; COPPER METABOLISM; ENZYME ACTIVATION; EPITHELIUM; KIDNEY CELL; KIDNEY MEDULLA; MAMMAL CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN MODIFICATION; RAT;

EID: 77952689891     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00257.2009     Document Type: Article

References (44)

1. Adams CM, Snyder PM, Welsh MJ. Interactions between subunits of the human epithelial sodium channel. J Biol Chem 272: 27295-27300, 1997. (Pubitemid 27452693)
2. Arteaga MF, Wang L, Ravid T, Hochstrasser M, Canessa CM. An amphipathic helix targets serum and glucocorticoid-induced kinase 1 to the endoplasmic reticulum-associated ubiquitin-conjugation machinery. Proc Natl Acad Sci USA 103: 11178-11183, 2006. (Pubitemid 44156492)
3. Belova L, Sharma S, Brickley DR, Nicolarsen JR, Patterson C, Conzen SD. Ubiquitin-proteasome degradation of serum- and glucocorticoid-regulated kinase-1 (SGK-1) is mediated by the chaperone-dependent E3 ligase CHIP. Biochem J 400: 235-244, 2006. (Pubitemid 44852037)
4. Biasio W, Chang T, McIntosh CJ, McDonald FJ. Identification of Murr1 as a regulator of the human delta epithelial sodium channel. J Biol Chem 279: 5429-5434, 2004. (Pubitemid 38220566)
5. Brickley DR, Mikosz CA, Hagan CR, Conzen SD. Ubiquitin modification of serum and glucocorticoid-induced protein kinase-1 (SGK-1). J Biol Chem 277: 43064-43070, 2002.
6. Burkhead JL, Morgan CT, Shinde U, Haddock G, Lutsenko S. COMMD1 forms oligomeric complexes targeted to the endocytic membranes via specific interactions with PtdIns(4,5)P2. J Biol Chem 284: 696-707, 2009.
7. Burstein E, Ganesh L, Dick RD, van De Sluis B, Wilkinson JC, Klomp LW, Wijmenga C, Brewer GJ, Nabel GJ, Duckett CS. A novel role for XIAP in copper homeostasis through regulation of MURR1. EMBO J 23: 244-254, 2004. (Pubitemid 38165764)
8. Burstein E, Hoberg JE, Wilkinson AS, Rumble JM, Csomos RA, Komarck CM, Maine GN, Wilkinson JC, Mayo MW, Duckett CS. COMMD proteins, a novel family of structural and functional homologs of MURR1. J Biol Chem 280: 22222-22232, 2005. (Pubitemid 40827879)
9. + channel is made of three homologous subunits. Nature 367: 463-467, 1994.
10. Chen SY, Bhargava A, Mastroberardino L, Meijer OC, Wang J, Buse P, Firestone GL, Verrey F, Pearce D. Epithelial sodium channel regulated by aldosterone-induced protein sgk. Proc Natl Acad Sci USA 96: 2514-2519, 1999. (Pubitemid 29117947)
11. De Bie P, van de Sluis B, Burstein E, van de Berghe PV, Muller P, Berger R, Gitlin JD, Wijmenga C, Klomp LW. Distinct Wilson's disease mutations in ATP7B are associated with enhanced binding to COMMD1 and reduced stability of ATP7B. Gastroenterology 133: 1316-1326, 2007. (Pubitemid 47494457)
12. + channel cell surface expression. EMBO J 20: 7052-7059, 2001.
13. Ganesh L, Burstein E, Guha-Niyogi A, Louder MK, Mascola JR, Klomp LW, Wijmenga C, Duckett CS, Nabel GJ. The gene product Murr1 restricts HIV-1 replication in resting CD4+ lymphocytes. Nature 426: 853-857, 2003. (Pubitemid 38056872)
14. Garty H, Palmer LG. Epithelial sodium channels: function, structure, and regulation. Physiol Rev 77: 359-396, 1997. (Pubitemid 27184343)
15. Lang F, Bohmer C, Palmada M, Seebohm G, Strutz-Seebohm N, Vallon V. (Patho)physiological significance of the serum- and glucocorticoid-inducible kinase isoforms. Physiol Rev 86: 1151-1178, 2006. (Pubitemid 44521650)
16. Lee IH, Campbell CR, Song SH, Day ML, Kumar S, Cook DI, Dinudom A. The activity of the epithelial sodium channels is regulated by Caveolin-1 via a Nedd4-2-dependent mechanism. J Biol Chem 284: 12663-12669, 2009.
17. Lee IH, Dinudom A, Sanchez-Perez A, Kumar S, Cook DI. Akt mediates the effect of insulin on epithelial sodium channels by inhibiting Nedd4-2. J Biol Chem 282: 29866-29873, 2007. (Pubitemid 350035273)
18. Liang X, Peters KW, Butterworth MB, Frizzell RA. 14-3-3 Isoforms are induced by aldosterone and participate in its regulation of epithelial sodium channels. J Biol Chem 281: 16323-16332, 2006. (Pubitemid 43909581)
19. Loffing J, Flores SY, Staub O. SGK kinases and their role in epithelial transport. Annu Rev Physiol 68: 461-490, 2006.
20. Maine GN, Burstein E. COMMD proteins: COMMing to the scene. Cell Mol Life Sci 64: 1997-2005, 2007.
21. Maine GN, Mao X, Komarck CM, Burstein E. COMMD1 promotes the ubiquitination of NF-κB subunits through a cullin-containing ubiquitin ligase. EMBO J 26: 436-447, 2007. (Pubitemid 46160944)
22. McDonald FJ, Price MP, Snyder PM, Welsh MJ. Cloning and expression of the β- and γ-subunits of the human epithelial sodium channel. Am J Physiol Cell Physiol 268: C1157-C1163, 1995.
23. + channel in mice: hyperkalemia and neonatal death associated with a pseudohypoaldosteronism phenotype. Proc Natl Acad Sci USA 96: 1727-1731, 1999.
24. Medina EA, Afsari RR, Ravid T, Castillo SS, Erickson KL, Goldkorn T. Tumor necrosis factor-α decreases Akt protein levels in 3T3-L1 adipocytes via the caspase-dependent ubiquitination of Akt. Endocrinology 146: 2726-2735, 2005. (Pubitemid 40695576)
25. Naray-Fejes-Toth A, Fejes-Toth G. The sgk, an aldosterone-induced gene in mineralocorticoid target cells, regulates the epithelial sodium channel. Kidney Int 57: 1290-1294, 2000. (Pubitemid 30207880)
26. Park J, Leong ML, Buse P, Maiyar AC, Firestone GL, Hemmings BA. Serum and glucocorticoid-inducible kinase (SGK) is a target of the PI 3-kinase-stimulated signaling pathway. EMBO J 18: 3024-3033, 1999. (Pubitemid 29255611)
27. Shi PP, Cao XR, Sweezer EM, Kinney TS, Williams NR, Husted RF, Nair R, Weiss RM, Williamson RA, Sigmund CD, Snyder PM, Staub O, Stokes JB, Yang B. Salt-sensitive hypertension and cardiac hypertrophy in mice deficient in the ubiquitin ligase Nedd4-2. Am J Physiol Renal Physiol 295: F462-F470, 2008.
28. Shimkets RA, Warnock DG, Bositis CM, Nelson-Williams C, Hansson JH, Schambelan M, Gill JR Jr, Ulick S, Milora RV, Findling JW. Liddle's syndrome: heritable human hypertension caused by mutations in the beta subunit of the epithelial sodium channel. Cell 79: 407-414, 1994. (Pubitemid 24346056)
29. + channel to the cell surface. J Clin Invest 105: 45-53, 2000.
30. + channel trafficking. Endocrinology 146: 5079-5085, 2005.
31. + channel through convergent phosphorylation of Nedd4-2. J Biol Chem 279: 45753-45758, 2004.
32. + channel by human Nedd4. J Biol Chem 276: 28321-28326, 2001.
33. + channel. J Biol Chem 277: 5-8, 2002.
34. Snyder PM, Steines JC, Olson DR. Relative contribution of Nedd4 and Nedd4-2 to ENaC regulation in epithelia determined by RNA interference. J Biol Chem 279: 5042-5046, 2004.
35. Staub O, Rotin D. Role of ubiquitylation in cellular membrane transport. Physiol Rev 86: 669-707, 2006.
36. Tanzi RE, Petrukhin K, Chernov I, Pellequer JL, Wasco W, Ross B, Romano DM, Parano E, Pavone L, Brzustowicz LM, Devoto M, Peppercorn J, Bush AI, Sternlieb I, Pirastu M, Gusella JF, Evgrafov O, Penchaszadeh GK, Honig B, Edelman IS, Soares MB, Scheinberg IH, Gilliam TC. The Wilson disease gene is a copper transporting ATPase with homology to the Menkes disease gene. Nat Genet 5: 344-350, 1993.
37. Van de Sluis B, Muller P, Duran K, Chen A, Groot AJ, Klomp LW, Liu PP, Wijmenga C. Increased activity of hypoxia-inducible factor 1 is associated with early embryonic lethality in Commd1 null mice. Mol Cell Biol 27: 4142-4156, 2007.
38. Van De Sluis B, Rothuizen J, Pearson PL, van Oost BA, Wijmenga C. Identification of a new copper metabolism gene by positional cloning in a purebred dog population. Hum Mol Genet 11: 165-173, 2002.
39. Wang J, Barbry P, Maiyar AC, Rozansky DJ, Bhargava A, Leong M, Firestone GL, Pearce D. SGK integrates insulin and mineralocorticoid regulation of epithelial sodium transport. Am J Physiol Renal Physiol 280: F303-F313, 2001.
40. Wang J, Knight ZA, Fiedler D, Williams O, Shokat KM, Pearce D. Activity of the p110-α subunit of phosphatidylinositol-3-kinase is required for activation of epithelial sodium transport. Am J Physiol Renal Physiol 295: F843-F850, 2008.
41. + currents in Xenopus laevis oocytes and fisher rat thyroid cells. J Biol Chem 282: 28264-28273, 2007.
42. Wulff P, Vallon V, Huang DY, Volkl H, Yu F, Richter K, Jansen M, Schlunz M, Klingel K, Loffing J, Kauselmann G, Bosl MR, Lang F, Kuhl D. Impaired renal Na+ retention in the sgk1-knockout mouse. J Clin Invest 110: 1263-1268, 2002.
43. Zhou R, Patel SV, Snyder PM. Nedd4-2 catalyzes ubiquitination and degradation of cell surface ENaC. J Biol Chem 282: 20207-20212, 2007.
44. Zhou R, Snyder PM. Nedd4-2 phosphorylation induces serum and glucocorticoid-regulated kinase (SGK) ubiquitination and degradation. J Biol Chem 280: 4518-4523, 2005.