Development of a new delivery system consisting in "drug - In cyclodextrin - In nanostructured lipid carriers" for ketoprofen topical delivery

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 80, Issue 1, 2012, Pages 46-53

  Cirri, M ^a   Bragagni, M ^a   Mennini, N ^a   Mura, P ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

Author keywords

Hydrogel; Ketoprofen; Nanostructured lipid carriers (NLC); Polymeric cyclodextrins; Topical formulation

Indexed keywords

CARBOXYMETHYL BETA CYCLODEXTRIN; CYCLODEXTRIN; EPICHLOROHYDRIN; GLYCEROL BEHENATE; KETOPROFEN; LABRAFAC; NANOMATERIAL; UNCLASSIFIED DRUG; XANTHAN;

ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG PENETRATION; DRUG RELEASE; DRUG SOLUBILITY; DRUG STABILITY; FREEZE DRYING; HYDROGEL; LIPID TRANSPORT; LIPOPHILICITY; NANOSTRUCTURED LIPID CARRIER; PARTICLE SIZE; PH; PHYSICAL CHEMISTRY; SKIN ABSORPTION;

ADMINISTRATION, TOPICAL; BETA-CYCLODEXTRINS; CHEMISTRY, PHARMACEUTICAL; CYCLODEXTRINS; DELAYED-ACTION PREPARATIONS; DRUG CARRIERS; DRUG STABILITY; EPICHLOROHYDRIN; FREEZE DRYING; HYDROGEL; KETOPROFEN; LIPIDS; NANOSTRUCTURES; PARTICLE SIZE; PERMEABILITY; POLYMERS; POLYSACCHARIDES, BACTERIAL; SOLUBILITY;

EID: 83955164252     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2011.07.015     Document Type: Article

References (38)

1. R.H. Müller, K. Mäder, and S. Gohla Solid lipid nanoparticles (SLN) for controlled drug delivery - a review of the state of the art Eur. J. Pharm. Biopharm. 50 2000 161 177 (Pubitemid 30326695)
2. W. Mehnert, and K. Mäder Solid lipid nanoparticles: production, characterization and applications Adv. Drug Deliv. Rev. 47 2001 165 196 (Pubitemid 32324113)
3. J. Pardeike, A. Hommoss, and R.H. Müller Lipid nanoparticles (SLN, LNC) in cosmetic and pharmaceutical dermal products Int. J. Pharm. 366 2009 170 184
4. R.H. Müller Lipid nanoparticles: recent advances Adv. Drug Del. Rev. 59 2007 375 376 (Pubitemid 47260708)
5. R.H. Müller, M. Radtke, and S.A. Wissing Nanostructured lipid matrices for improved microencapsulation of drug Int. J. Pharm. 242 2002 121 128
6. E.B. Souto, and R.H. Müller Polymorphic behaviour of Compritol 888 ATO as bulk lipid and as SLN and NLC J. Microencapsul. 23 2006 377 388
7. A. Brioschi, F. Zenga, G.P. Zara, M.R. Gasco, A. Ducati, and A. Mauro Solid lipid nanoparticles: could they help to improve the efficacy of pharmacologic treatments for brain tumors? Neurol. Res. 29 2007 324 330 (Pubitemid 46802372)
8. M. Schäfer-Korting, W. Mehnert, and H.C. Korting Lipid nanoparticles for improved topical application of drugs for skin diseases Adv. Drug Deliv. Rev. 59 2007 427 443 (Pubitemid 47259224)
9. L. Priano, D. Esposti, R. Esposti, G. Castagna, C. De Medici, F. Fraschini, M.R. Gasco, and A. Mauro Solid lipid nanoparticles incorporating melatonin as new model for sustained oral and transdermal delivery systems J. Nanosci. Nanotechnol. 7 2007 3596 3601
10. Z. Mei, H. Chen, T. Weng, Y. Yang, and X. Yang Solid lipid nanoparticle and microemulsion for topical delivery of triptolide Eur. J. Pharm. Biopharm. 56 2003 189 196 (Pubitemid 37072102)
11. M. Joshi, and V. Patravale Nanostructured lipid carrier (NLC) based gel of celecoxib Int. J. Pharm. 346 2008 124 132 (Pubitemid 350110507)
12. C. Puglia, P. Blasi, L. Rizza, A. Schoubben, F. Bonina, C. Rossi, and M. Ricci Lipid nanoparticles for prolonged topical delivery: an in vitro and in vivo investigation Int. J. Pharm. 357 2008 295 304
13. Y. Nakai, K. Yamamoto, K. Terada, and K. Akimoto The dispersed states of medicinal molecules in ground mixtures with α- or β-cyclodextrin Chem. Pharm. Bull. 32 1984 685 690
14. P. Mura, G.P. Bettinetti, A. Manderioli, M.T. Faucci, G. Bramanti, and M. Sorrenti Interactions of ketoprofen and ibuprofen with β-cyclodextrins in solution and in the solid state Int. J. Pharm. 166 1998 189 203 (Pubitemid 28255226)
15. P. Mura, M.T. Faucci, P.L. Parrini, S. Furlanetto, and S. Pinzauti Influence of the preparation method on the physicochemical properties of ketoprofen-cyclodextrin binary systems Int. J. Pharm. 179 1999 117 128 (Pubitemid 29115066)
16. J. Rautio, T. Nevalainen, H. Taipale, J. Vepsalainen, J. Gynther, K. Laine, and T. Jarvinen Piperazinylalkyl prodrugs of naproxen improve in vitro skin permeation Eur. J. Pharm. Sci. 11 2000 157 163 (Pubitemid 30479857)
17. F. Bonina, C. Puglia, T. Barbuzzi, P. De Caprariis, F. Palagiano, M.G. Rimoli, and A. Saija In vitro and in vivo evaluation of polyoxyethylene esters as dermal prodrugs of ketoprofen, naproxen and diclofenac Eur. J. Pharm. Sci. 14 2001 123 134
18. F. Maestrelli, M.L. Gonzlez-Rodrguez, A.M. Rabasco, and P. Mura Preparation and characterisation of liposomes encapsulating ketoprofen- cyclodextrin complexes for transdermal drug delivery Int. J. Pharm. 298 2005 55 67 (Pubitemid 40834315)
19. L. Szente, and J. Szejtli Highly soluble cyclodextrin derivatives: chemistry, properties, and trends in development Adv. Drug Deliv. Rev. 36 1999 17 28 (Pubitemid 29074474)
20. A.M. Layre, N.M. Gosselet, E. Renard, B. Sebille, and C. Amiel Comparison of the complexation of cosmetic and pharmaceutical compounds with γ-cyclodextrin, 2-hydroxypropyl-β-cyclodextrin and water-soluble β-cyclodextrin-co-epichlorohydrin polymers J. Incl. Phenom. Macrocycl. Chem. 43 2002 311 317 (Pubitemid 38075764)
21. M. Ricci, C. Puglia, F. Bonina, C. Di Giovanni, S. Giovagnoli, and C. Rossi Evaluation of indomethacin percutaneous absorption from nanostructured lipid carriers (NLC): in vitro and in vivo studies J. Pharm. Sci. 94 2005 1149 1159 (Pubitemid 40780779)
22. H.A. Barnes, J.F. Hutton, and K. Walters An Introduction to Rheology 1989 Elsevier Science Amsterdam
23. P. Mura, L. Celesti, D. Proietti, S. Corsi, S. Furlanetto, and P. Corti In vitro studies of simulated percutaneous absorption: influence of artificial membrane impregnation agent Acta Technol. Leg. Med. 4 1993 121 136
24. M. Cirri, F. Maestrelli, S. Furlanetto, and P. Mura Solid-state characterization of glyburide-cyclodextrin co-ground products J. Therm. Anal. Calorim. 77 2004 413 422
25. A. Wongmekiat, Y. Tozuka, T. Oguchi, and K. Yamamoto Formation of fine drug particle by cogrinding with cyclodextrins. Part II. The influence of moisture condition during cogrinding process on fine particle formation Int. J. Pharm. 265 2003 85 93 (Pubitemid 37176949)
26. A. Wongmekiat, s. Yoshimatsu, Y. Tozuka, K. Moribe, and K. Yamamoto Investigation of drug nanoparticle formation by co-grinding with cyclodextrins: studies for indomethacin, furosemide and naproxen J. Incl. Phenom. Macroc. Chem. 56 2009 29 32
27. N. Ogawa, K. Higashi, H. Nagase, T. Endo, K. Moribe, T. Loftsson, K. Yamamoto, and H. Ueda Effects of cogrinding with β-cyclodextrin on the solid state of fentanyl J. Pharm. Sci. 99 2010 5019 5029
28. G.G. Liversidge Analytical Profiles of Drug Substances K. Florey, 1981 Academic Press New York 443 471
29. P. Briard, and J.C. Rossi Ketoprofen Acta Crystallogr. Sect. C 46 1990 1036 1038
30. E.B. Souto, S.A. Wissing, C.M. Barbosa, and R.H. Müller Development of a controlled release formulation based on SLN and NLC for topical clotrimazole delivery Int. J. Pharm. 278 2004 1 7
31. R. Cavalli, E. Peira, O. Caputo, and M.R. Gasco Solid lipid nanoparticles as carriers of hydrocortisone and progesterone complexes with β-cyclodextrins Int. J. Pharm. 182 1999 59 69 (Pubitemid 29229795)
32. A. Lippacher, R.H. Müller, and K. Mäder Semisolid SLN dispersions for topical application: influence of formulation and production parameters on viscoelastic properties Eur. J. Pharm. Biopharm. 53 2002 155 160 (Pubitemid 34189788)
33. K.A. Shah, A.A. Date, M.D. Joshi, and V.B. Patravale Solid lipid nanoparticles (SLN) of tretinoin: potential in topical delivery Int. J. Pharm. 345 2007 163 171 (Pubitemid 350087549)
34. J. Houk, and R.H. Guy Membrane models for skin penetration studies Chem. Rev. 88 1988 455 471
35. M.M. Feldstein, I.M. Raigorodskii, A.L. Iordanskii, and J. Hadgraft Modeling of percutaneous drug transport in vitro using skin-imitating Carbosil membrane J. Control. Release 52 1998 25 40 (Pubitemid 28123170)
36. H. Dureja, A.K. Tiwary, and S. Gupta Simulation of skin permeability in chitosan membranes Int. J. Pharm. 213 2001 193 198 (Pubitemid 32119475)
37. F. Maestrelli, M.L. Gonzlez-Rodrguez, A.M. Rabasco, and P. Mura Effect of preparation of preparation technique on the properties of liposomes encapsulating ketoprofen-cyclodextrin complexes aimed for transdermal drug delivery Int. J. Pharm. 312 2006 53 60
38. V.M. Rao, J.L. Haslam, and V.J. Stella Controlled and complete release of a model poorly water-soluble drug, prednisolone, from hydroxypropyl methylcellulose matrix tablets using (SBE)-beta-cyclodextrin as a solubilizing agent J. Pharm. Sci. 90 2001 807 816 (Pubitemid 32645939)