Rapid detection of bla IMP-6 by amplification refractory mutation system

Journal of Microbiological Methods

Volumn 88, Issue 1, 2012, Pages 182-184

  Kayama, Shizuo ^a,b   Shigemoto, Norifumi ^a,b   Kuwahara, Ryuichi ^a,b   Onodera, Makoto ^a,c   Yokozaki, Michiya ^a,c   Ohge, Hiroki ^a,b,c   Kato, Fuminori ^a,b   Hisatsune, Jyunzo ^a,b   Sugai, Motoyuki ^a,b  

^a HIROSHIMA UNIVERSITY   (Japan)

^b HIROSHIMA UNIVERSITY   (Japan)

^c HIROSHIMA UNIVERSITY HOSPITAL   (Japan)

Author keywords

ARMS; BlaIMP 6; Klebsiella pneumoniae; Metallo lactamase; PCR

Indexed keywords

AMPLIFICATION REFRACTORY MUTATION SYSTEM; ARTICLE; BACTERIAL GENE; BLAIMP 1 GENE; BLAIMP 6 GENE; CONTROLLED STUDY; GENE AMPLIFICATION; GENE IDENTIFICATION; KLEBSIELLA PNEUMONIAE; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROCESS DEVELOPMENT; ANTIBIOTIC RESISTANCE; DRUG EFFECT; ENZYMOLOGY; EVALUATION; GENETICS; HUMAN; ISOLATION AND PURIFICATION; JAPAN; KLEBSIELLA INFECTION; METHODOLOGY; MICROBIOLOGICAL EXAMINATION; MICROBIOLOGY; MUTATION;

KLEBSIELLA; KLEBSIELLA PNEUMONIAE;

ANTIINFECTIVE AGENT; BACTERIAL PROTEIN; BETA LACTAMASE; IMIPENEM;

ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; BETA-LACTAMASES; DRUG RESISTANCE, BACTERIAL; HUMANS; IMIPENEM; JAPAN; KLEBSIELLA INFECTIONS; KLEBSIELLA PNEUMONIAE; MICROBIAL SENSITIVITY TESTS; MUTATION; POLYMERASE CHAIN REACTION;

EID: 83955163604     PISSN: 01677012     EISSN: 18728359     Source Type: Journal    
DOI: 10.1016/j.mimet.2011.10.022     Document Type: Article

References (18)

1. Carrer A., Poirel L., Yilmaz M., Akan O.A., Feriha C., Cuzon G. Spread of OXA-48-encoding plasmid in Turkey and beyond. Antimicrob. Agents Chemother. 2010, 54:1369-1373.
2. Clinical and Laboratory Standards Institute Performance standards for antimicrobial susceptibility testing. 20th Informational Supplement. M100-S20, CLSI, Wayne, PA 2010.
3. Donohoe G.G., Salomaki A., Lehtimaki T., Pulkki K., Kairisto V. Rapid identification of apolipoprotein E genotypes by multiplex amplification refractory mutation system PCR and capillary gel electrophoresis. Clin. Chem. 1999, 45:143-146.
4. Fan X.-Y., Hu Z.-Y., Xu F.-H., Yan Z.-Q., Guo S.-Q., Li Z.-M. Rapid detection of rpoB gene mutations in rifampin-resistant Mycobacterium tuberculosis isolates in Shanghai by using the amplification refractory mutation system. J. Clin. Microbiol. 2003, 41:993-997.
5. Ferrie R.M., Schwarz M.J., Robertson N.H., Vaudin S., Super M., Malone G., Little S. Development, multiplexing, and application of ARMS tests for common mutations in the CFTR gene. Am. J. Hum. Genet. 1992, 51:251-262.
6. Giakkoupi P., Tzouvelekis L.S., Daikos G.L., Miriagou V., Petrikkos G., Legakis N.J., Vatopoulos A.C. Discrepancies and interpretation problems in susceptibility testing of VIM-1-producing Klebsiella pneumoniae isolates. J. Clin. Microbiol. 2005, 43:494-496.
7. Kim S.-Y., Park Y.-J., Yu J.-K., Kim H.S., Park Y.S., Yoon J.-B., Yoo J.-Y., Lee K. Prevalence and mechanisms of decreased susceptibility to carbapenems in Klebsiella pneumoniae isolates. Diagn. Microbiol. Infect. Dis. 2007, 57:85-91.
8. Koh T.H., Sng L.-H., Babini G.S., Woodford N., Livermore D.M., Hall L.M.C. Carbapenem-resistant Klebsiella pneumoniae in Singapore producing IMP-1 ß-lactamase and lacking an outer membrane protein. Antimicrob. Agents Chemother. 2001, 45:1939-1940.
9. IMP-1 gene cassette in Hiroshima. J. Antimicrob. Chemother. 2009, 64:46-51.
10. Kumarasamy K.K., Toleman M.A., Walsh T.R., Bagaria J., Balakrishnan R. Emergence of a new antibiotic resistance mechanism in India, Pakistan, and the UK: a molecular, biological, and epidemiological study. Lancet Infect. Dis. 2010, 10:597-602.
11. Newton C.R., Graham A., Heptinstall L.E., Powell S.J., Summers C., Kalsheker N., Smith J.C., Markham A.F. Analysis of any point mutation in DNA. The amplification refractory mutation system (ARMS). Nucleic Acids Res. 1989, 17:2503-2516.
12. Nordmann P., Cuzon G., Naas T. Klebsiella pneumoniae carbapenemase-producing bacteria. Lancet Infect. Dis. 2009, 9:228-236.
13. Shigemoto, N., Kuwahara, R., Kayama, S., Shimizu, W., Onodera, M., Yokozaki, M., Hisatsune, J., Kato, F., Ohge, H., Sugai, M., (in press). Emergence in Japan of an imipenem-susceptible meropenem-resistant Klebsiella pneumoniae (ISMRK) carrying blaIMP-6. Diagn Microbiol. Infect. Dis. (2011 Nov 10, Electronic publication ahead of print). PMID: 22078906.
14. Tenover F.C., Kalsi R.K., Williams P.P., Carey R.B., Stocker S., Lonsway D., Rasheed J.K., Biddle J.W., McGowan J.E., Hanna B. Carbapenem resistance in Klebsiella pneumoniae not detected by automated susceptibility testing. Emerg. Infect. Dis. 2006, 12:1209-1213.
15. Vatopoulos A. High rates of metallo-ß-lactamase-producing Klebsiella pneumoniae in Greece - a review of the current evidence. Euro Surveill. 2008, 13:8023.
16. Weisenberg S.A., Morgan D.J., Espinal-Witter R., Larone D.H. Clinical outcomes of patients with Klebsiella pneumoniae carbapenemase-producing K. pneumoniae after treatment with imipenem or meropenem. Diagn. Microbiol. Infect. Dis. 2009, 64:233-235.
17. Woodford N., Eastaway A.T., Ford M., Leanord A., Keane C., Quayle R.M., Steer J.A., Jiancheng Z., Livermore D.M. Comparison of BD Phonix, Vitek 2, and MicoScan automated systems for detection and inference of mechanisms responsible for carbapenem resistance in Enterobacteriaceae. J. Clin. Microbiol. 2010, 48:2999-3002.
18. Yano H., Kuga A., Okamoto R., Kitasato H., Kobayashi T., Inoue M. Plasmid-encoded metallo-ß-lactamase (IMP-6) conferring resistance to carbapenems, especially meropenem. Antimicrob. Agents Chemother. 2001, 45:1343-1348.